Adipocytes cause leukemia cell resistance to l-asparaginase via release of glutamine

Cancer Research

Volumn 73, Issue 10, 2013, Pages 2998-3006

  Ehsanipour, Ehsan A ^a   Sheng, Xia ^a   Behan, James W ^a   Wang, Xingchao ^c   Butturini, Anna ^a,b,d,f   Avramis, Vassilios I ^a,b,d,f   Mittelman, Steven D ^a,d,e,f  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b Hematology and Oncology ^*  (United States)

^c University of Colorado Anschutz Medical Campus   (United States)

^d UMHC   (United States)

^e Physiology and Biophysics   (United States)

^f UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINASE; ASPARAGINE; GLUTAMATE AMMONIA LIGASE; GLUTAMINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADIPOCYTE; ADULT; AMINO ACID BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CHEMOTHERAPY; CANCER RESISTANCE; CELL COUNT; CELL FUNCTION; CELL PROTECTION; CHILD; CLINICAL ARTICLE; COCULTURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; HUMAN; HUMAN TISSUE; LEUKEMIA CELL; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; SCHOOL CHILD; SINGLE DRUG DOSE; TUMOR MICROENVIRONMENT;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; ASPARAGINASE; GLUTAMINE; HUMANS; LEUKEMIA; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; OBESITY; TUMOR MICROENVIRONMENT;

EID: 84877845591     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-4402     Document Type: Article

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