메뉴 건너뛰기




Volumn 205, Issue 4, 2016, Pages 381-395

PA-X-associated early alleviation of the acute lung injury contributes to the attenuation of a highly pathogenic H5N1 avian influenza virus in mice

Author keywords

ALI; Highly pathogenic H5N1 AIV; Mice; PA X; Pathogenesis

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C5A; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PROTEIN MX 1; PROTEIN PA X; RANTES; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS PROTEIN; COMPLEMENT; PA-X PROTEIN, INFLUENZA A VIRUS; REPRESSOR PROTEIN; VIRAL PROTEIN;

EID: 84978148936     PISSN: 03008584     EISSN: 14321831     Source Type: Journal    
DOI: 10.1007/s00430-016-0461-2     Document Type: Article
Times cited : (22)

References (89)
  • 2
    • 0017326035 scopus 로고
    • The genes of influenza virus
    • COI: 1:CAS:528:DyaE2sXhtFOgsrk%3D, PID: 837439
    • Palese P (1977) The genes of influenza virus. Cell 10(1):1–10. doi:10.1016/0092-8674(77)90133-7
    • (1977) Cell , vol.10 , Issue.1 , pp. 1-10
    • Palese, P.1
  • 3
    • 0018973537 scopus 로고
    • Sequence of interrupted and uninterrupted mRNAs and cloned DNA coding for the two overlapping nonstructural proteins of influenza virus
    • COI: 1:CAS:528:DyaL3MXht1KitA%3D%3D, PID: 7407920
    • Lamb RA, Lai CJ (1980) Sequence of interrupted and uninterrupted mRNAs and cloned DNA coding for the two overlapping nonstructural proteins of influenza virus. Cell 21(2):475–485. doi:10.1016/0092-8674(80)90484-5
    • (1980) Cell , vol.21 , Issue.2 , pp. 475-485
    • Lamb, R.A.1    Lai, C.J.2
  • 5
    • 67749133883 scopus 로고    scopus 로고
    • A complicated message: Identification of a novel PB1-related protein translated from influenza A virus segment 2 mRNA
    • COI: 1:CAS:528:DC%2BD1MXpsFOlt7w%3D, PID: 19494001
    • Wise HM, Foeglein A, Sun J, Dalton RM, Patel S, Howard W, Anderson EC, Barclay WS, Digard P (2009) A complicated message: Identification of a novel PB1-related protein translated from influenza A virus segment 2 mRNA. J Virol 83(16):8021–8031. doi:10.1128/JVI.00826-09
    • (2009) J Virol , vol.83 , Issue.16 , pp. 8021-8031
    • Wise, H.M.1    Foeglein, A.2    Sun, J.3    Dalton, R.M.4    Patel, S.5    Howard, W.6    Anderson, E.C.7    Barclay, W.S.8    Digard, P.9
  • 8
    • 84874044936 scopus 로고    scopus 로고
    • Adaptive mutation in influenza A virus non-structural gene is linked to host switching and induces a novel protein by alternative splicing
    • Selman M, Dankar SK, Forbes NE, Jia J-J, Brown EG (2012) Adaptive mutation in influenza A virus non-structural gene is linked to host switching and induces a novel protein by alternative splicing. Emerg Microb Infect 1(11):e42. doi:10.1038/emi.2012.38
    • (2012) Emerg Microb Infect , vol.1 , Issue.11 , pp. 42
    • Selman, M.1    Dankar, S.K.2    Forbes, N.E.3    Jia, J.-J.4    Brown, E.G.5
  • 9
    • 84874676641 scopus 로고    scopus 로고
    • Identification of novel influenza A virus proteins translated from PA mRNA
    • COI: 1:CAS:528:DC%2BC3sXltVOjsbY%3D, PID: 23236060
    • Muramoto Y, Noda T, Kawakami E, Akkina R, Kawaoka Y (2013) Identification of novel influenza A virus proteins translated from PA mRNA. J Virol 87(5):2455–2462. doi:10.1128/JVI.02656-12
    • (2013) J Virol , vol.87 , Issue.5 , pp. 2455-2462
    • Muramoto, Y.1    Noda, T.2    Kawakami, E.3    Akkina, R.4    Kawaoka, Y.5
  • 10
    • 84953889017 scopus 로고    scopus 로고
    • Identification of A novel viral protein expressed from the PB2 segment of influenza A virus
    • Yamayoshi S, Watanabe M, Goto H, Kawaoka Y (2015) Identification of A novel viral protein expressed from the PB2 segment of influenza A virus. J Virol. doi:10.1128/JVI.02175-15
    • (2015) J Virol
    • Yamayoshi, S.1    Watanabe, M.2    Goto, H.3    Kawaoka, Y.4
  • 11
    • 84929576523 scopus 로고    scopus 로고
    • Influenza A virus protein PA-X contributes to viral growth and suppression of the host antiviral and immune responses
    • COI: 1:CAS:528:DC%2BC2MXpsFCqsrk%3D, PID: 25855745
    • Hayashi T, MacDonald LA, Takimoto T (2015) Influenza A virus protein PA-X contributes to viral growth and suppression of the host antiviral and immune responses. J Virol 89(12):6442–6452. doi:10.1128/JVI.00319-15
    • (2015) J Virol , vol.89 , Issue.12 , pp. 6442-6452
    • Hayashi, T.1    MacDonald, L.A.2    Takimoto, T.3
  • 12
    • 84921643356 scopus 로고    scopus 로고
    • Influenza virus M2 protein ion channel activity helps to maintain pandemic 2009 H1N1 virus hemagglutinin fusion competence during transport to the cell surface
    • PID: 25473053
    • Alvarado-Facundo E, Gao Y, Ribas-Aparicio RM, Jimenez-Alberto A, Weiss CD, Wang W (2015) Influenza virus M2 protein ion channel activity helps to maintain pandemic 2009 H1N1 virus hemagglutinin fusion competence during transport to the cell surface. J Virol 89(4):1975–1985. doi:10.1128/JVI.03253-14
    • (2015) J Virol , vol.89 , Issue.4 , pp. 1975-1985
    • Alvarado-Facundo, E.1    Gao, Y.2    Ribas-Aparicio, R.M.3    Jimenez-Alberto, A.4    Weiss, C.D.5    Wang, W.6
  • 14
    • 84938145002 scopus 로고    scopus 로고
    • Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity
    • COI: 1:CAS:528:DC%2BC28Xis1Khurg%3D, PID: 25877935
    • Gao H, Sun H, Hu J, Qi L, Wang J, Xiong X, Wang Y, He Q, Lin Y, Kong W, Seng LG, Pu J, Chang KC, Liu X, Liu J, Sun Y (2015) Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity. J Gen Virol 96(8):2036–2049. doi:10.1099/vir.0.000143
    • (2015) J Gen Virol , vol.96 , Issue.8 , pp. 2036-2049
    • Gao, H.1    Sun, H.2    Hu, J.3    Qi, L.4    Wang, J.5    Xiong, X.6    Wang, Y.7    He, Q.8    Lin, Y.9    Kong, W.10    Seng, L.G.11    Pu, J.12    Chang, K.C.13    Liu, X.14    Liu, J.15    Sun, Y.16
  • 15
    • 84925424679 scopus 로고    scopus 로고
    • PA-X decreases the pathogenicity of highly pathogenic H5N1 influenza A virus in avian species by inhibiting virus replication and host response
    • COI: 1:CAS:528:DC%2BC2MXlvVWltLg%3D, PID: 25631083
    • Hu J, Mo Y, Wang X, Gu M, Hu Z, Zhong L, Wu Q, Hao X, Hu S, Liu W, Liu H, Liu X (2015) PA-X decreases the pathogenicity of highly pathogenic H5N1 influenza A virus in avian species by inhibiting virus replication and host response. J Virol 89(8):4126–4142. doi:10.1128/JVI.02132-14
    • (2015) J Virol , vol.89 , Issue.8 , pp. 4126-4142
    • Hu, J.1    Mo, Y.2    Wang, X.3    Gu, M.4    Hu, Z.5    Zhong, L.6    Wu, Q.7    Hao, X.8    Hu, S.9    Liu, W.10    Liu, H.11    Liu, X.12
  • 16
    • 84874699713 scopus 로고    scopus 로고
    • Identification of the N-terminal domain of the influenza virus PA responsible for the suppression of host protein synthesis
    • COI: 1:CAS:528:DC%2BC3sXlsV2hsr8%3D, PID: 23283952
    • Desmet EA, Bussey KA, Stone R, Takimoto T (2013) Identification of the N-terminal domain of the influenza virus PA responsible for the suppression of host protein synthesis. J Virol 87(6):3108–3118. doi:10.1128/JVI.02826-12
    • (2013) J Virol , vol.87 , Issue.6 , pp. 3108-3118
    • Desmet, E.A.1    Bussey, K.A.2    Stone, R.3    Takimoto, T.4
  • 17
    • 84905371432 scopus 로고    scopus 로고
    • Influenza a virus host shutoff disables antiviral stress-induced translation arrest
    • PID: 25010204
    • Khaperskyy DA, Emara MM, Johnston BP, Anderson P, Hatchette TF, McCormick C (2014) Influenza a virus host shutoff disables antiviral stress-induced translation arrest. PLoS Pathog 10(7):e1004217. doi:10.1371/journal.ppat.1004217
    • (2014) PLoS Pathog , vol.10 , Issue.7 , pp. 1004217
    • Khaperskyy, D.A.1    Emara, M.M.2    Johnston, B.P.3    Anderson, P.4    Hatchette, T.F.5    McCormick, C.6
  • 18
    • 84938149452 scopus 로고    scopus 로고
    • Mapping of a region of the PA-X protein of influenza A virus that is important for its shutoff activity
    • COI: 1:CAS:528:DC%2BC2MXht12hsbbL, PID: 26041295
    • Oishi K, Yamayoshi S, Kawaoka Y (2015) Mapping of a region of the PA-X protein of influenza A virus that is important for its shutoff activity. J Virol 89(16):8661–8665. doi:10.1128/Jvi.01132-15
    • (2015) J Virol , vol.89 , Issue.16 , pp. 8661-8665
    • Oishi, K.1    Yamayoshi, S.2    Kawaoka, Y.3
  • 19
    • 84930892539 scopus 로고    scopus 로고
    • Timing is everything: coordinated control of host shutoff by influenza A virus NS1 and PA-X proteins
    • COI: 1:CAS:528:DC%2BC2MXhtVGntrjM, PID: 25878098
    • Khaperskyy DA, McCormick C (2015) Timing is everything: coordinated control of host shutoff by influenza A virus NS1 and PA-X proteins. J Virol 89(13):6528–6531. doi:10.1128/Jvi.00386-15
    • (2015) J Virol , vol.89 , Issue.13 , pp. 6528-6531
    • Khaperskyy, D.A.1    McCormick, C.2
  • 20
    • 84939215721 scopus 로고    scopus 로고
    • Impact of influenza PA-X on host response
    • PID: 26305985
    • Hayashi T, Chaimayo C, Takimoto T (2015) Impact of influenza PA-X on host response. Oncotarget 6(23):19364–19365. doi:10.18632/oncotarget.5127
    • (2015) Oncotarget , vol.6 , Issue.23 , pp. 19364-19365
    • Hayashi, T.1    Chaimayo, C.2    Takimoto, T.3
  • 21
    • 84959423192 scopus 로고    scopus 로고
    • The novel influenza A virus protein PA-X and its naturally deleted variant show different enzymatic properties in comparison to the viral endonuclease PA
    • COI: 1:CAS:528:DC%2BC28XosVCiu7k%3D, PID: 26384413
    • Bavagnoli L, Cucuzza S, Campanini G, Rovida F, Paolucci S, Baldanti F, Maga G (2015) The novel influenza A virus protein PA-X and its naturally deleted variant show different enzymatic properties in comparison to the viral endonuclease PA. Nucleic Acids Res 43(19):9405–9417. doi:10.1093/nar/gkv926
    • (2015) Nucleic Acids Res , vol.43 , Issue.19 , pp. 9405-9417
    • Bavagnoli, L.1    Cucuzza, S.2    Campanini, G.3    Rovida, F.4    Paolucci, S.5    Baldanti, F.6    Maga, G.7
  • 23
    • 84888583372 scopus 로고    scopus 로고
    • Caspase-1 deficient mice are more susceptible to influenza A virus infection with PA variation
    • COI: 1:CAS:528:DC%2BC3sXhslajtb3F, PID: 23901080
    • Huang CH, Chen CJ, Yen CT, Yu CP, Huang PN, Kuo RL, Lin SJ, Chang CK, Shih SR (2013) Caspase-1 deficient mice are more susceptible to influenza A virus infection with PA variation. J Infect Dis 208(11):1898–1905. doi:10.1093/infdis/jit381
    • (2013) J Infect Dis , vol.208 , Issue.11 , pp. 1898-1905
    • Huang, C.H.1    Chen, C.J.2    Yen, C.T.3    Yu, C.P.4    Huang, P.N.5    Kuo, R.L.6    Lin, S.J.7    Chang, C.K.8    Shih, S.R.9
  • 24
    • 79952774962 scopus 로고    scopus 로고
    • High genetic compatibility and increased pathogenicity of reassortants derived from avian H9N2 and pandemic H1N1/2009 influenza viruses
    • COI: 1:CAS:528:DC%2BC3MXjsF2ntb4%3D, PID: 21368167
    • Sun Y, Qin K, Wang J, Pu J, Tang Q, Hu Y, Bi Y, Zhao X, Yang H, Shu Y, Liu J (2011) High genetic compatibility and increased pathogenicity of reassortants derived from avian H9N2 and pandemic H1N1/2009 influenza viruses. Proc Natl Acad Sci USA 108(10):4164–4169. doi:10.1073/pnas.1019109108
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.10 , pp. 4164-4169
    • Sun, Y.1    Qin, K.2    Wang, J.3    Pu, J.4    Tang, Q.5    Hu, Y.6    Bi, Y.7    Zhao, X.8    Yang, H.9    Shu, Y.10    Liu, J.11
  • 25
    • 77955609166 scopus 로고    scopus 로고
    • Antineoplastic effects of gamma linolenic Acid on hepatocellular carcinoma cell lines
    • COI: 1:CAS:528:DC%2BC3cXhtFKjsrrP, PID: 20664735
    • Itoh S, Taketomi A, Harimoto N, Tsujita E, Rikimaru T, Shirabe K, Shimada M, Maehara Y (2010) Antineoplastic effects of gamma linolenic Acid on hepatocellular carcinoma cell lines. J Clin Biochem Nutr 47(1):81–90. doi:10.3164/jcbn.10-24
    • (2010) J Clin Biochem Nutr , vol.47 , Issue.1 , pp. 81-90
    • Itoh, S.1    Taketomi, A.2    Harimoto, N.3    Tsujita, E.4    Rikimaru, T.5    Shirabe, K.6    Shimada, M.7    Maehara, Y.8
  • 26
    • 33947417049 scopus 로고    scopus 로고
    • Role of host cytokine responses in the pathogenesis of avian H5N1 influenza viruses in mice
    • COI: 1:CAS:528:DC%2BD2sXjt1GrsbY%3D, PID: 17182684
    • Szretter KJ, Gangappa S, Lu X, Smith C, Shieh WJ, Zaki SR, Sambhara S, Tumpey TM, Katz JM (2007) Role of host cytokine responses in the pathogenesis of avian H5N1 influenza viruses in mice. J Virol 81(6):2736–2744. doi:10.1128/JVI.02336-06
    • (2007) J Virol , vol.81 , Issue.6 , pp. 2736-2744
    • Szretter, K.J.1    Gangappa, S.2    Lu, X.3    Smith, C.4    Shieh, W.J.5    Zaki, S.R.6    Sambhara, S.7    Tumpey, T.M.8    Katz, J.M.9
  • 27
    • 50849097044 scopus 로고    scopus 로고
    • H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice
    • PID: 18670648
    • Perrone LA, Plowden JK, Garcia-Sastre A, Katz JM, Tumpey TM (2008) H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice. PLoS Pathog 4(8):e1000115. doi:10.1371/journal.ppat.1000115
    • (2008) PLoS Pathog , vol.4 , Issue.8 , pp. 1000115
    • Perrone, L.A.1    Plowden, J.K.2    Garcia-Sastre, A.3    Katz, J.M.4    Tumpey, T.M.5
  • 31
    • 84883146711 scopus 로고    scopus 로고
    • Inhibition of complement activation alleviates acute lung injury induced by highly pathogenic avian influenza H5N1 virus infection
    • COI: 1:CAS:528:DC%2BC3sXht1elt7zO, PID: 23526211
    • Sun S, Zhao G, Liu C, Wu X, Guo Y, Yu H, Song H, Du L, Jiang S, Guo R, Tomlinson S, Zhou Y (2013) Inhibition of complement activation alleviates acute lung injury induced by highly pathogenic avian influenza H5N1 virus infection. Am J Respir Cell Mol Biol 49(2):221–230. doi:10.1165/rcmb.2012-0428OC
    • (2013) Am J Respir Cell Mol Biol , vol.49 , Issue.2 , pp. 221-230
    • Sun, S.1    Zhao, G.2    Liu, C.3    Wu, X.4    Guo, Y.5    Yu, H.6    Song, H.7    Du, L.8    Jiang, S.9    Guo, R.10    Tomlinson, S.11    Zhou, Y.12
  • 32
    • 84928879766 scopus 로고    scopus 로고
    • The role of C5a in acute lung injury induced by highly pathogenic viral infections
    • COI: 1:CAS:528:DC%2BC2MXotVCjsLc%3D
    • Wang R, Xiao H, Guo R, Li Y, Shen B (2015) The role of C5a in acute lung injury induced by highly pathogenic viral infections. Emerg Microb Infect 4(5):e28. doi:10.1038/emi.2015.28
    • (2015) Emerg Microb Infect , vol.4 , Issue.5 , pp. 28
    • Wang, R.1    Xiao, H.2    Guo, R.3    Li, Y.4    Shen, B.5
  • 36
    • 17444403917 scopus 로고    scopus 로고
    • C5a negatively regulates toll-like receptor 4-induced immune responses
    • COI: 1:CAS:528:DC%2BD2MXktFKru78%3D, PID: 15845447
    • Hawlisch H, Belkaid Y, Baelder R, Hildeman D, Gerard C, Kohl J (2005) C5a negatively regulates toll-like receptor 4-induced immune responses. Immunity 22(4):415–426. doi:10.1016/j.immuni.2005.02.006
    • (2005) Immunity , vol.22 , Issue.4 , pp. 415-426
    • Hawlisch, H.1    Belkaid, Y.2    Baelder, R.3    Hildeman, D.4    Gerard, C.5    Kohl, J.6
  • 39
    • 0029958972 scopus 로고    scopus 로고
    • Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals
    • COI: 1:CAS:528:DyaK28XhvVSktLk%3D, PID: 8637894
    • Akaike T, Noguchi Y, Ijiri S, Setoguchi K, Suga M, Zheng YM, Dietzschold B, Maeda H (1996) Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci USA 93(6):2448–2453
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.6 , pp. 2448-2453
    • Akaike, T.1    Noguchi, Y.2    Ijiri, S.3    Setoguchi, K.4    Suga, M.5    Zheng, Y.M.6    Dietzschold, B.7    Maeda, H.8
  • 40
    • 0025193910 scopus 로고
    • Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice
    • COI: 1:CAS:528:DyaK3cXhslKgsr0%3D, PID: 2155924
    • Akaike T, Ando M, Oda T, Diii T, Ijiri S, Araki S, Maeda H (1990) Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice. J Clin Invest 85(3):739–745. doi:10.1172/JCI114499
    • (1990) J Clin Invest , vol.85 , Issue.3 , pp. 739-745
    • Akaike, T.1    Ando, M.2    Oda, T.3    Diii, T.4    Ijiri, S.5    Araki, S.6    Maeda, H.7
  • 41
    • 0026050165 scopus 로고
    • Oxygen free radicals as pathogenic molecules in viral diseases
    • COI: 1:CAS:528:DyaK3MXmsFejs78%3D, PID: 1656471
    • Maeda H, Akaike T (1991) Oxygen free radicals as pathogenic molecules in viral diseases. Proc Soc Exp Biol Med 198(2):721–727
    • (1991) Proc Soc Exp Biol Med , vol.198 , Issue.2 , pp. 721-727
    • Maeda, H.1    Akaike, T.2
  • 43
    • 84855779811 scopus 로고    scopus 로고
    • Suppressing production of reactive oxygen species (ROS) for influenza A virus therapy
    • COI: 1:CAS:528:DC%2BC38XovFektw%3D%3D, PID: 21962460
    • Vlahos R, Stambas J, Selemidis S (2012) Suppressing production of reactive oxygen species (ROS) for influenza A virus therapy. Trends Pharmacol Sci 33(1):3–8. doi:10.1016/j.tips.2011.09.001
    • (2012) Trends Pharmacol Sci , vol.33 , Issue.1 , pp. 3-8
    • Vlahos, R.1    Stambas, J.2    Selemidis, S.3
  • 44
    • 84887132810 scopus 로고    scopus 로고
    • Oxygen free radical involvement in acute lung injury induced by H5N1 virus in mice
    • COI: 1:CAS:528:DC%2BC3sXhslCrsbrM, PID: 23336583
    • He G, Dong C, Luan Z, McAllan BM, Xu T, Zhao L, Qiao J (2013) Oxygen free radical involvement in acute lung injury induced by H5N1 virus in mice. Influenza Other Respir Viruses 7(6):945–953. doi:10.1111/irv.12067
    • (2013) Influenza Other Respir Viruses , vol.7 , Issue.6 , pp. 945-953
    • He, G.1    Dong, C.2    Luan, Z.3    McAllan, B.M.4    Xu, T.5    Zhao, L.6    Qiao, J.7
  • 45
    • 84923064735 scopus 로고    scopus 로고
    • Inhibition of reactive oxygen species production ameliorates inflammation induced by influenza A viruses via upregulation of SOCS1 and SOCS3
    • PID: 25520513
    • Ye S, Lowther S, Stambas J (2015) Inhibition of reactive oxygen species production ameliorates inflammation induced by influenza A viruses via upregulation of SOCS1 and SOCS3. J Virol 89(5):2672–2683. doi:10.1128/JVI.03529-14
    • (2015) J Virol , vol.89 , Issue.5 , pp. 2672-2683
    • Ye, S.1    Lowther, S.2    Stambas, J.3
  • 46
    • 84921856790 scopus 로고    scopus 로고
    • NADPH oxidases as novel pharmacologic targets against influenza A virus infection
    • PID: 25301784
    • Vlahos R, Selemidis S (2014) NADPH oxidases as novel pharmacologic targets against influenza A virus infection. Mol Pharmacol 86(6):747–759. doi:10.1124/mol.114.095216
    • (2014) Mol Pharmacol , vol.86 , Issue.6 , pp. 747-759
    • Vlahos, R.1    Selemidis, S.2
  • 47
    • 84926363335 scopus 로고    scopus 로고
    • Oxidative stress and free radicals in COPD implications and relevance for treatment
    • COI: 1:CAS:528:DC%2BC2cXitFGgsLrO
    • Domej W, Oettl K, Renner W (2014) Oxidative stress and free radicals in COPD implications and relevance for treatment. Int J Chronic Obstr 9:1207–1224. doi:10.2147/Copd.S51226
    • (2014) Int J Chronic Obstr , vol.9 , pp. 1207-1224
    • Domej, W.1    Oettl, K.2    Renner, W.3
  • 51
    • 67650930744 scopus 로고    scopus 로고
    • Association of increased pathogenicity of Asian H5N1 highly pathogenic avian influenza viruses in chickens with highly efficient viral replication accompanied by early destruction of innate immune responses
    • COI: 1:CAS:528:DC%2BD1MXovFensbo%3D, PID: 19457987
    • Suzuki K, Okada H, Itoh T, Tada T, Mase M, Nakamura K, Kubo M, Tsukamoto K (2009) Association of increased pathogenicity of Asian H5N1 highly pathogenic avian influenza viruses in chickens with highly efficient viral replication accompanied by early destruction of innate immune responses. J Virol 83(15):7475–7486. doi:10.1128/JVI.01434-08
    • (2009) J Virol , vol.83 , Issue.15 , pp. 7475-7486
    • Suzuki, K.1    Okada, H.2    Itoh, T.3    Tada, T.4    Mase, M.5    Nakamura, K.6    Kubo, M.7    Tsukamoto, K.8
  • 52
    • 84875015344 scopus 로고    scopus 로고
    • Lessons learned and concepts formed from study of the pathogenesis of the two negative-strand viruses lymphocytic choriomeningitis and influenza
    • COI: 1:CAS:528:DC%2BC3sXmtV2rtbo%3D, PID: 23341590
    • Oldstone MB (2013) Lessons learned and concepts formed from study of the pathogenesis of the two negative-strand viruses lymphocytic choriomeningitis and influenza. Proc Natl Acad Sci USA 110(11):4180–4183. doi:10.1073/pnas.1222025110
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.11 , pp. 4180-4183
    • Oldstone, M.B.1
  • 53
    • 84902012250 scopus 로고    scopus 로고
    • Early cytokine dysregulation and viral replication are associated with mortality during lethal influenza infection
    • COI: 1:CAS:528:DC%2BC2cXptVansb4%3D, PID: 24787235
    • Vogel AJ, Harris S, Marsteller N, Condon SA, Brown DM (2014) Early cytokine dysregulation and viral replication are associated with mortality during lethal influenza infection. Viral Immunol 27(5):214–224. doi:10.1089/vim.2013.0095
    • (2014) Viral Immunol , vol.27 , Issue.5 , pp. 214-224
    • Vogel, A.J.1    Harris, S.2    Marsteller, N.3    Condon, S.A.4    Brown, D.M.5
  • 54
    • 0028278094 scopus 로고
    • Apoptosis: a mechanism of cell killing by influenza A and B viruses
    • COI: 1:CAS:528:DyaK2cXjt1Snurw%3D, PID: 8189504
    • Hinshaw VS, Olsen CW, Dybdahl-Sissoko N, Evans D (1994) Apoptosis: a mechanism of cell killing by influenza A and B viruses. J Virol 68(6):3667–3673
    • (1994) J Virol , vol.68 , Issue.6 , pp. 3667-3673
    • Hinshaw, V.S.1    Olsen, C.W.2    Dybdahl-Sissoko, N.3    Evans, D.4
  • 55
    • 0034975633 scopus 로고    scopus 로고
    • Human lymphocyte apoptosis after exposure to influenza A virus
    • COI: 1:CAS:528:DC%2BD3MXksFGmt78%3D, PID: 11390593
    • Nichols JE, Niles JA, Roberts NJ Jr (2001) Human lymphocyte apoptosis after exposure to influenza A virus. J Virol 75(13):5921–5929. doi:10.1128/JVI.73.13.5921-5929.2001
    • (2001) J Virol , vol.75 , Issue.13 , pp. 5921-5929
    • Nichols, J.E.1    Niles, J.A.2    Roberts, N.J.3
  • 56
    • 40149111112 scopus 로고    scopus 로고
    • Avian influenza virus A/HK/483/97(H5N1) NS1 protein induces apoptosis in human airway epithelial cells
    • COI: 1:CAS:528:DC%2BD1cXjtVart7c%3D, PID: 18199656
    • Lam WY, Tang JW, Yeung AC, Chiu LC, Sung JJ, Chan PK (2008) Avian influenza virus A/HK/483/97(H5N1) NS1 protein induces apoptosis in human airway epithelial cells. J Virol 82(6):2741–2751. doi:10.1128/JVI.01712-07
    • (2008) J Virol , vol.82 , Issue.6 , pp. 2741-2751
    • Lam, W.Y.1    Tang, J.W.2    Yeung, A.C.3    Chiu, L.C.4    Sung, J.J.5    Chan, P.K.6
  • 57
    • 0030704753 scopus 로고    scopus 로고
    • Differential induction of cytotoxicity and apoptosis by influenza virus strains of differing virulence
    • COI: 1:CAS:528:DyaK2sXntVyhsLo%3D, PID: 9367368
    • Price GE, Smith H, Sweet C (1997) Differential induction of cytotoxicity and apoptosis by influenza virus strains of differing virulence. J Gen Virol 78(Pt 11):2821–2829
    • (1997) J Gen Virol , vol.78 , pp. 2821-2829
    • Price, G.E.1    Smith, H.2    Sweet, C.3
  • 58
    • 0034872412 scopus 로고    scopus 로고
    • Influenza virus ns1 protein induces apoptosis in cultured cells
    • COI: 1:CAS:528:DC%2BD3MXmtFejt7w%3D, PID: 11483732
    • Schultz-Cherry S, Dybdahl-Sissoko N, Neumann G, Kawaoka Y, Hinshaw VS (2001) Influenza virus ns1 protein induces apoptosis in cultured cells. J Virol 75(17):7875–7881
    • (2001) J Virol , vol.75 , Issue.17 , pp. 7875-7881
    • Schultz-Cherry, S.1    Dybdahl-Sissoko, N.2    Neumann, G.3    Kawaoka, Y.4    Hinshaw, V.S.5
  • 59
    • 23744512890 scopus 로고    scopus 로고
    • Role of apoptosis and cytokines in influenza virus morbidity
    • COI: 1:CAS:528:DC%2BD2MXos1WktLg%3D, PID: 16102605
    • Brydon EW, Morris SJ, Sweet C (2005) Role of apoptosis and cytokines in influenza virus morbidity. FEMS Microbiol Rev 29(4):837–850. doi:10.1016/j.femsre.2004.12.003
    • (2005) FEMS Microbiol Rev , vol.29 , Issue.4 , pp. 837-850
    • Brydon, E.W.1    Morris, S.J.2    Sweet, C.3
  • 60
    • 0034051290 scopus 로고    scopus 로고
    • Depletion of lymphocytes and diminished cytokine production in mice infected with a highly virulent influenza A (H5N1) virus isolated from humans
    • COI: 1:CAS:528:DC%2BD3cXkt1eiu7s%3D, PID: 10846094
    • Tumpey TM, Lu X, Morken T, Zaki SR, Katz JM (2000) Depletion of lymphocytes and diminished cytokine production in mice infected with a highly virulent influenza A (H5N1) virus isolated from humans. J Virol 74(13):6105–6116
    • (2000) J Virol , vol.74 , Issue.13 , pp. 6105-6116
    • Tumpey, T.M.1    Lu, X.2    Morken, T.3    Zaki, S.R.4    Katz, J.M.5
  • 61
    • 33750523632 scopus 로고    scopus 로고
    • NF-kappa B activation by reactive oxygen species: fifteen years later
    • COI: 1:CAS:528:DC%2BD28XhtFOjtrfK, PID: 16723122
    • Gloire G, Legrand-Poels S, Piette J (2006) NF-kappa B activation by reactive oxygen species: fifteen years later. Biochem Pharmacol 72(11):1493–1505. doi:10.1016/j.bcp.2006.04.011
    • (2006) Biochem Pharmacol , vol.72 , Issue.11 , pp. 1493-1505
    • Gloire, G.1    Legrand-Poels, S.2    Piette, J.3
  • 62
    • 0031036917 scopus 로고    scopus 로고
    • An essential role for free radicals and derived species in signal transduction
    • COI: 1:CAS:528:DyaK2sXhtlGntL0%3D, PID: 9039953
    • Lander HM (1997) An essential role for free radicals and derived species in signal transduction. FASEB J 11(2):118–124
    • (1997) FASEB J , vol.11 , Issue.2 , pp. 118-124
    • Lander, H.M.1
  • 63
    • 0031435786 scopus 로고    scopus 로고
    • Oxidative stress in human immunodeficiency virus infection
    • COI: 1:CAS:528:DyaK1cXhsVWmsQ%3D%3D, PID: 9447238
    • Israel N, Gougerot-Pocidalo MA (1997) Oxidative stress in human immunodeficiency virus infection. Cell Mol Life Sci 53(11–12):864–870
    • (1997) Cell Mol Life Sci , vol.53 , Issue.11-12 , pp. 864-870
    • Israel, N.1    Gougerot-Pocidalo, M.A.2
  • 64
    • 33645459044 scopus 로고    scopus 로고
    • Biomarkers of oxidative damage in human disease
    • COI: 1:CAS:528:DC%2BD28Xjt1Gruro%3D, PID: 16484333
    • Dalle-Donne I, Rossi R, Colombo R, Giustarini D, Milzani A (2006) Biomarkers of oxidative damage in human disease. Clin Chem 52(4):601–623. doi:10.1373/clinchem.2005.061408
    • (2006) Clin Chem , vol.52 , Issue.4 , pp. 601-623
    • Dalle-Donne, I.1    Rossi, R.2    Colombo, R.3    Giustarini, D.4    Milzani, A.5
  • 65
    • 0027297036 scopus 로고
    • Apoptosis in AIDS
    • COI: 1:STN:280:DyaK3s3mt1CrsA%3D%3D, PID: 8098552
    • Gougeon ML, Montagnier L (1993) Apoptosis in AIDS. Science 260(5112):1269–1270
    • (1993) Science , vol.260 , Issue.5112 , pp. 1269-1270
    • Gougeon, M.L.1    Montagnier, L.2
  • 66
    • 0029162485 scopus 로고
    • The role of oxidative stress in HIV disease
    • COI: 1:CAS:528:DyaK2MXnsVynu74%3D, PID: 7590404
    • Pace GW, Leaf CD (1995) The role of oxidative stress in HIV disease. Free Radic Biol Med 19(4):523–528. doi:10.1016/0891-5849(95)00047-2
    • (1995) Free Radic Biol Med , vol.19 , Issue.4 , pp. 523-528
    • Pace, G.W.1    Leaf, C.D.2
  • 68
    • 0024294357 scopus 로고
    • Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor
    • COI: 1:CAS:528:DyaL1cXktlaqu7s%3D, PID: 3129195
    • Baeuerle PA, Baltimore D (1988) Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor. Cell 53(2):211–217. doi:10.1016/0092-8674(88)90382-0
    • (1988) Cell , vol.53 , Issue.2 , pp. 211-217
    • Baeuerle, P.A.1    Baltimore, D.2
  • 69
    • 0025677250 scopus 로고
    • Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus
    • COI: 1:CAS:528:DyaK3MXls12juw%3D%3D, PID: 2263644
    • Staal FJ, Roederer M, Herzenberg LA (1990) Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus. Proc Natl Acad Sci USA 87(24):9943–9947
    • (1990) Proc Natl Acad Sci USA , vol.87 , Issue.24 , pp. 9943-9947
    • Staal, F.J.1    Roederer, M.2    Herzenberg, L.A.3
  • 70
    • 0031569468 scopus 로고    scopus 로고
    • Direct demonstration of delayed eosinophil apoptosis as a mechanism causing tissue eosinophilia
    • COI: 1:CAS:528:DyaK2sXisFCltLY%3D, PID: 9103460
    • Simon HU, Yousefi S, Schranz C, Schapowal A, Bachert C, Blaser K (1997) Direct demonstration of delayed eosinophil apoptosis as a mechanism causing tissue eosinophilia. J Immunol 158(8):3902–3908
    • (1997) J Immunol , vol.158 , Issue.8 , pp. 3902-3908
    • Simon, H.U.1    Yousefi, S.2    Schranz, C.3    Schapowal, A.4    Bachert, C.5    Blaser, K.6
  • 71
    • 0033539507 scopus 로고    scopus 로고
    • Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation
    • COI: 1:CAS:528:DyaK1MXns1Gmt7c%3D
    • Dibbert B, Weber M, Nikolaizik WH, Vogt P, Schoni MH, Blaser K, Simon HU (1999) Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation. P Natl Acad Sci USA 96(23):13330–13335. doi:10.1073/pnas.96.23.13330
    • (1999) P Natl Acad Sci USA , vol.96 , Issue.23 , pp. 13330-13335
    • Dibbert, B.1    Weber, M.2    Nikolaizik, W.H.3    Vogt, P.4    Schoni, M.H.5    Blaser, K.6    Simon, H.U.7
  • 72
    • 0028556421 scopus 로고
    • Neutrophils, host defense, and inflammation: a double-edged sword
    • COI: 1:CAS:528:DyaK2MXis1Kgtr0%3D, PID: 7996043
    • Smith JA (1994) Neutrophils, host defense, and inflammation: a double-edged sword. J Leukoc Biol 56(6):672–686
    • (1994) J Leukoc Biol , vol.56 , Issue.6 , pp. 672-686
    • Smith, J.A.1
  • 73
    • 79952213095 scopus 로고    scopus 로고
    • Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation
    • COI: 1:CAS:528:DC%2BC3MXitVGgsLg%3D, PID: 21304882
    • Vlahos R, Stambas J, Bozinovski S, Broughton BR, Drummond GR, Selemidis S (2011) Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation. PLoS Pathog 7(2):e1001271. doi:10.1371/journal.ppat.1001271
    • (2011) PLoS Pathog , vol.7 , Issue.2 , pp. 1001271
    • Vlahos, R.1    Stambas, J.2    Bozinovski, S.3    Broughton, B.R.4    Drummond, G.R.5    Selemidis, S.6
  • 74
    • 84875983841 scopus 로고    scopus 로고
    • Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress
    • COI: 1:CAS:528:DC%2BC3sXmtlSmt7o%3D, PID: 23577160
    • Selemidis S, Seow HJ, Broughton BR, Vinh A, Bozinovski S, Sobey CG, Drummond GR, Vlahos R (2013) Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress. PLoS One 8(4):e60792. doi:10.1371/journal.pone.0060792
    • (2013) PLoS One , vol.8 , Issue.4 , pp. 60792
    • Selemidis, S.1    Seow, H.J.2    Broughton, B.R.3    Vinh, A.4    Bozinovski, S.5    Sobey, C.G.6    Drummond, G.R.7    Vlahos, R.8
  • 75
    • 0036104834 scopus 로고    scopus 로고
    • Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection
    • COI: 1:CAS:528:DC%2BD38XivVGmtb4%3D, PID: 11927943
    • Kopf M, Abel B, Gallimore A, Carroll M, Bachmann MF (2002) Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection. Nat Med 8(4):373–378. doi:10.1038/nm0402-373
    • (2002) Nat Med , vol.8 , Issue.4 , pp. 373-378
    • Kopf, M.1    Abel, B.2    Gallimore, A.3    Carroll, M.4    Bachmann, M.F.5
  • 76
    • 5444259851 scopus 로고    scopus 로고
    • The complement system in regulation of adaptive immunity
    • COI: 1:CAS:528:DC%2BD2cXnvFCgsrk%3D, PID: 15454921
    • Carroll MC (2004) The complement system in regulation of adaptive immunity. Nat Immunol 5(10):981–986. doi:10.1038/ni1113ni1113
    • (2004) Nat Immunol , vol.5 , Issue.10 , pp. 981-986
    • Carroll, M.C.1
  • 78
    • 79952073504 scopus 로고    scopus 로고
    • Complement and viral pathogenesis
    • COI: 1:CAS:528:DC%2BC3MXjs1Kjsrw%3D, PID: 21292294
    • Stoermer KA, Morrison TE (2011) Complement and viral pathogenesis. Virology 411(2):362–373. doi:10.1016/j.virol.2010.12.045
    • (2011) Virology , vol.411 , Issue.2 , pp. 362-373
    • Stoermer, K.A.1    Morrison, T.E.2
  • 79
    • 0034861323 scopus 로고    scopus 로고
    • Anaphylatoxins and infectious and non-infectious inflammatory diseases
    • COI: 1:CAS:528:DC%2BD3MXmt1GmsLc%3D, PID: 11532279
    • Kohl J (2001) Anaphylatoxins and infectious and non-infectious inflammatory diseases. Mol Immunol 38(2–3):175–187. doi:10.1016/S0161-5890(01)00041-4
    • (2001) Mol Immunol , vol.38 , Issue.2-3 , pp. 175-187
    • Kohl, J.1
  • 80
    • 11144224478 scopus 로고    scopus 로고
    • An interferon-gamma-related cytokine storm in SARS patients
    • COI: 1:CAS:528:DC%2BD2MXntFyhsw%3D%3D, PID: 15602737
    • Huang KJ, Su IJ, Theron M, Wu YC, Lai SK, Liu CC, Lei HY (2005) An interferon-gamma-related cytokine storm in SARS patients. J Med Virol 75(2):185–194. doi:10.1002/jmv.20255
    • (2005) J Med Virol , vol.75 , Issue.2 , pp. 185-194
    • Huang, K.J.1    Su, I.J.2    Theron, M.3    Wu, Y.C.4    Lai, S.K.5    Liu, C.C.6    Lei, H.Y.7
  • 81
    • 84898850857 scopus 로고    scopus 로고
    • Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis
    • COI: 1:CAS:528:DC%2BC2cXmsFeqs7g%3D, PID: 24065148
    • Zhou J, Chu H, Li C, Wong BH, Cheng ZS, Poon VK, Sun T, Lau CC, Wong KK, Chan JY, Chan JF, To KK, Chan KH, Zheng BJ, Yuen KY (2014) Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis. J Infect Dis 209(9):1331–1342. doi:10.1093/infdis/jit504
    • (2014) J Infect Dis , vol.209 , Issue.9 , pp. 1331-1342
    • Zhou, J.1    Chu, H.2    Li, C.3    Wong, B.H.4    Cheng, Z.S.5    Poon, V.K.6    Sun, T.7    Lau, C.C.8    Wong, K.K.9    Chan, J.Y.10    Chan, J.F.11    To, K.K.12    Chan, K.H.13    Zheng, B.J.14    Yuen, K.Y.15
  • 82
    • 0038371106 scopus 로고    scopus 로고
    • Threonine 157 of influenza virus PA polymerase subunit modulates RNA replication in infectious viruses
    • COI: 1:CAS:528:DC%2BD3sXjs1Oksb4%3D, PID: 12719592
    • Huarte M, Falcon A, Nakaya Y, Ortin J, Garcia-Sastre A, Nieto A (2003) Threonine 157 of influenza virus PA polymerase subunit modulates RNA replication in infectious viruses. J Virol 77(10):6007–6013
    • (2003) J Virol , vol.77 , Issue.10 , pp. 6007-6013
    • Huarte, M.1    Falcon, A.2    Nakaya, Y.3    Ortin, J.4    Garcia-Sastre, A.5    Nieto, A.6
  • 83
    • 40349113426 scopus 로고    scopus 로고
    • Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus
    • PID: 18248089
    • Gabriel G, Herwig A, Klenk HD (2008) Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus. PLoS Pathog 4(2):e11. doi:10.1371/journal.ppat.0040011
    • (2008) PLoS Pathog , vol.4 , Issue.2 , pp. 11
    • Gabriel, G.1    Herwig, A.2    Klenk, H.D.3
  • 84
    • 84886932306 scopus 로고    scopus 로고
    • The PA and HA gene-mediated high viral load and intense innate immune response in the brain contribute to the high pathogenicity of H5N1 avian influenza virus in mallard ducks
    • COI: 1:CAS:528:DC%2BC3sXhsF2ksr3E, PID: 23926340
    • Hu J, Hu Z, Mo Y, Wu Q, Cui Z, Duan Z, Huang J, Chen H, Chen Y, Gu M, Wang X, Hu S, Liu H, Liu W, Liu X (2013) The PA and HA gene-mediated high viral load and intense innate immune response in the brain contribute to the high pathogenicity of H5N1 avian influenza virus in mallard ducks. J Virol 87(20):11063–11075. doi:10.1128/JVI.00760-13
    • (2013) J Virol , vol.87 , Issue.20 , pp. 11063-11075
    • Hu, J.1    Hu, Z.2    Mo, Y.3    Wu, Q.4    Cui, Z.5    Duan, Z.6    Huang, J.7    Chen, H.8    Chen, Y.9    Gu, M.10    Wang, X.11    Hu, S.12    Liu, H.13    Liu, W.14    Liu, X.15
  • 85
    • 34848897191 scopus 로고    scopus 로고
    • Influenza A virus PB1-F2: a small protein with a big punch
    • COI: 1:CAS:528:DC%2BD2sXht1CntLvO, PID: 18005736
    • Conenello GM, Palese P (2007) Influenza A virus PB1-F2: a small protein with a big punch. Cell Host Microbe 2(4):207–209. doi:10.1016/j.chom.2007.09.010
    • (2007) Cell Host Microbe , vol.2 , Issue.4 , pp. 207-209
    • Conenello, G.M.1    Palese, P.2
  • 87
    • 82955168464 scopus 로고    scopus 로고
    • The influenza A virus protein PB1-F2: killing two birds with one stone?
    • PID: 21971186
    • Varga ZT, Palese P (2011) The influenza A virus protein PB1-F2: killing two birds with one stone? Virulence 2(6):542–546. doi:10.4161/viru.2.6.17812
    • (2011) Virulence , vol.2 , Issue.6 , pp. 542-546
    • Varga, Z.T.1    Palese, P.2
  • 88
    • 84876793270 scopus 로고    scopus 로고
    • An insight into the PB1F2 protein and its multifunctional role in enhancing the pathogenicity of the influenza A viruses
    • COI: 1:CAS:528:DC%2BC3sXltVCrsbc%3D, PID: 23545143
    • Chakrabarti AK, Pasricha G (2013) An insight into the PB1F2 protein and its multifunctional role in enhancing the pathogenicity of the influenza A viruses. Virology 440(2):97–104. doi:10.1016/j.virol.2013.02.025
    • (2013) Virology , vol.440 , Issue.2 , pp. 97-104
    • Chakrabarti, A.K.1    Pasricha, G.2
  • 89
    • 84884337399 scopus 로고    scopus 로고
    • The multifaceted effect of PB1-F2 specific antibodies on influenza A virus infection
    • COI: 1:CAS:528:DC%2BC3sXhs1yqt7fE, PID: 24210094
    • Kosik I, Krejnusova I, Praznovska M, Russ G (2013) The multifaceted effect of PB1-F2 specific antibodies on influenza A virus infection. Virology 447(1–2):1–8. doi:10.1016/j.virol.2013.08.022
    • (2013) Virology , vol.447 , Issue.1-2 , pp. 1-8
    • Kosik, I.1    Krejnusova, I.2    Praznovska, M.3    Russ, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.