The PA and HA gene-mediated high viral load and intense innate immune response in the brain contribute to the high pathogenicity of H5N1 avian influenza virus in mallard ducks

Journal of Virology

Volumn 87, Issue 20, 2013, Pages 11063-11075

  Hu, Jiao ^a   Hu, Zenglei ^a   Mo, Yiqun ^a   Wu, Qiwen ^a   Cui, Zhu ^a   Duan, Zhiqiang ^a   Huang, Junqing ^a   Chen, Hongzhi ^a   Chen, Yuxin ^a   Gu, Min ^a   Wang, Xiaoquan ^a   Hu, Shunlin ^a   Liu, Huimou ^a   Liu, Wenbo ^a   Liu, Xiaowen ^a   Liu, Xiufan ^a  

^a YANGZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HEMAGGLUTININ;

ANAS PLATYRHYNCHOS; ANIMAL CELL; ARTICLE; BRAIN; CONTROLLED STUDY; DUCK; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; GENETIC REASSORTMENT; GENETIC SIMILARITY; HUMAN; HUMAN CELL; INFLUENZA VIRUS A H5N1; INNATE IMMUNITY; LUNG; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SPLEEN; VIRUS GENE; VIRUS ISOLATION; VIRUS LOAD; VIRUS MUTANT; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; DNA MUTATIONAL ANALYSIS; DUCKS; GENETIC ENGINEERING; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; IMMUNITY, INNATE; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA IN BIRDS; REASSORTANT VIRUSES; RNA REPLICASE; VIRAL LOAD; VIRAL PROTEINS; VIRULENCE; VIRULENCE FACTORS; VIRUS REPLICATION;

EID: 84886932306     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00760-13     Document Type: Article

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