-
1
-
-
0020595851
-
Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity
-
Rogers GN, Paulson JC, Daniels RS, Skehel JJ, Wilson IA, Wiley DC. 1983. Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity. Nature 304:76-78. http://dx.doi.org/10.1038/304076a0.
-
(1983)
Nature
, vol.304
, pp. 76-78
-
-
Rogers, G.N.1
Paulson, J.C.2
Daniels, R.S.3
Skehel, J.J.4
Wilson, I.A.5
Wiley, D.C.6
-
2
-
-
0033783032
-
Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin
-
Skehel JJ, Wiley DC. 2000. Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. Annu Rev Biochem 69:531-569. http://dx.doi.org/10.1146/annurev.biochem.69.1.531.
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 531-569
-
-
Skehel, J.J.1
Wiley, D.C.2
-
3
-
-
0028855669
-
Electron microscopy of antibody complexes of influenza virus haemagglutinin in the fusion pH conformation
-
Wharton SA, Calder LJ, Ruigrok RW, Skehel JJ, Steinhauer DA, Wiley DC. 1995. Electron microscopy of antibody complexes of influenza virus haemagglutinin in the fusion pH conformation. EMBO J 14:240-246.
-
(1995)
EMBO J
, vol.14
, pp. 240-246
-
-
Wharton, S.A.1
Calder, L.J.2
Ruigrok, R.W.3
Skehel, J.J.4
Steinhauer, D.A.5
Wiley, D.C.6
-
4
-
-
34447299235
-
Orthomyxoviridae: the viruses and their replication
-
Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (ed), 5th ed, Lippincott Williams & Wilkins, Philadelphia, PA
-
Palese P, Shaw ML. 2007. Orthomyxoviridae: the viruses and their replication, p 1648-1689. In Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (ed), Fields virology, 5th ed, vol 2. Lippincott Williams & Wilkins, Philadelphia, PA.
-
(2007)
Fields virology
, vol.2
, pp. 1648-1689
-
-
Palese, P.1
Shaw, M.L.2
-
5
-
-
0027103930
-
Influence of amantadine resistance mutations on the pH regulatory function of the M2 protein of influenza A viruses
-
Grambas S, Bennett MS, Hay AJ. 1992. Influence of amantadine resistance mutations on the pH regulatory function of the M2 protein of influenza A viruses. Virology 191:541-549. http://dx.doi.org/10.1016/0042-6822(92)90229-I.
-
(1992)
Virology
, vol.191
, pp. 541-549
-
-
Grambas, S.1
Bennett, M.S.2
Hay, A.J.3
-
6
-
-
0026772384
-
Evidence that the amantadine-induced, M2-mediated conversion of influenza A virus hemagglutinin to the low pH conformation occurs in an acidic trans Golgi compartment
-
Ciampor F, Bayley PM, Nermut MV, Hirst EM, Sugrue RJ, Hay AJ. 1992. Evidence that the amantadine-induced, M2-mediated conversion of influenza A virus hemagglutinin to the low pH conformation occurs in an acidic trans Golgi compartment. Virology 188:14-24. http://dx.doi.org/10.1016/0042-6822(92)90730-D.
-
(1992)
Virology
, vol.188
, pp. 14-24
-
-
Ciampor, F.1
Bayley, P.M.2
Nermut, M.V.3
Hirst, E.M.4
Sugrue, R.J.5
Hay, A.J.6
-
7
-
-
0029929748
-
The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus
-
Sakaguchi T, Leser GP, Lamb RA. 1996. The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus. J Cell Biol 133:733-747. http://dx.doi.org/10.1083/jcb.133.4.733.
-
(1996)
J Cell Biol
, vol.133
, pp. 733-747
-
-
Sakaguchi, T.1
Leser, G.P.2
Lamb, R.A.3
-
8
-
-
0028177960
-
Influenza virus M2 protein ion channel activity stabilizes the native form of fowl plague virus hemagglutinin during intracellular transport
-
Takeuchi K, Lamb RA. 1994. Influenza virus M2 protein ion channel activity stabilizes the native form of fowl plague virus hemagglutinin during intracellular transport. J Virol 68:911-919.
-
(1994)
J Virol
, vol.68
, pp. 911-919
-
-
Takeuchi, K.1
Lamb, R.A.2
-
9
-
-
0026787707
-
Maturation of influenza A virus hemagglutinin-estimates of the pH encountered during transport and its regulation by the M2 protein
-
Grambas S, Hay AJ. 1992. Maturation of influenza A virus hemagglutinin-estimates of the pH encountered during transport and its regulation by the M2 protein. Virology 190:11-18. http://dx.doi.org/10.1016/0042-6822(92)91187-Y.
-
(1992)
Virology
, vol.190
, pp. 11-18
-
-
Grambas, S.1
Hay, A.J.2
-
10
-
-
33645767668
-
Influenza M2 envelope protein augments avian influenza hemagglutinin pseudotyping of lentiviral vector
-
McKay TM, Patel M, Pickles RJ, Johnson LG, Olsen JC. 2006. Influenza M2 envelope protein augments avian influenza hemagglutinin pseudotyping of lentiviral vector. Gene Ther 13:715-724. http://dx.doi.org/10.1038/sj.gt.3302715.
-
(2006)
Gene Ther
, vol.13
, pp. 715-724
-
-
McKay, T.M.1
Patel, M.2
Pickles, R.J.3
Johnson, L.G.4
Olsen, J.C.5
-
11
-
-
0028081894
-
Rescue of vector-expressed fowl plague virus hemagglutinin in biologically active form by acidotropic agents and coexpressed M2 protein
-
Ohuchi M, Cramer A, Vey M, Ohuchi R, Garten W, Klenk HD. 1994. Rescue of vector-expressed fowl plague virus hemagglutinin in biologically active form by acidotropic agents and coexpressed M2 protein. J Virol 68:920-926.
-
(1994)
J Virol
, vol.68
, pp. 920-926
-
-
Ohuchi, M.1
Cramer, A.2
Vey, M.3
Ohuchi, R.4
Garten, W.5
Klenk, H.D.6
-
12
-
-
0026343370
-
Amantadine selection of a mutant influenza virus containing an acidstable hemagglutinin glycoprotein: evidence for virus-specific regulation of the pH of glycoprotein transport vesicles
-
Steinhauer DA, Wharton SA, Skehel JJ, Wiley DC, Hay AJ. 1991. Amantadine selection of a mutant influenza virus containing an acidstable hemagglutinin glycoprotein: evidence for virus-specific regulation of the pH of glycoprotein transport vesicles. Proc Natl Acad Sci USA 88:11525-11529. http://dx.doi.org/10.1073/pnas.88.24.11525.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 11525-11529
-
-
Steinhauer, D.A.1
Wharton, S.A.2
Skehel, J.J.3
Wiley, D.C.4
Hay, A.J.5
-
13
-
-
0345734193
-
Restrictions to the adaptation of influenza A virus H5 hemagglutinin to the human host
-
Harvey R, Martin AC, Zambon M, Barclay WS. 2004. Restrictions to the adaptation of influenza A virus H5 hemagglutinin to the human host. J Virol 78:502-507. http://dx.doi.org/10.1128/JVI.78.1.502-507.2004.
-
(2004)
J Virol
, vol.78
, pp. 502-507
-
-
Harvey, R.1
Martin, A.C.2
Zambon, M.3
Barclay, W.S.4
-
14
-
-
77956637693
-
Influenza virus M2 protein mediates ESCRT-independent membrane scission
-
Rossman JS, Jing X, Leser GP, Lamb RA. 2010. Influenza virus M2 protein mediates ESCRT-independent membrane scission. Cell 142:902-913. http://dx.doi.org/10.1016/j.cell.2010.08.029.
-
(2010)
Cell
, vol.142
, pp. 902-913
-
-
Rossman, J.S.1
Jing, X.2
Leser, G.P.3
Lamb, R.A.4
-
15
-
-
79952069060
-
Influenza virus assembly and budding
-
Rossman JS, Lamb RA. 2011. Influenza virus assembly and budding. Virology 41:229-236. http://dx.doi.org/10.1016/j.virol.2010.12.003.
-
(2011)
Virology
, vol.41
, pp. 229-236
-
-
Rossman, J.S.1
Lamb, R.A.2
-
16
-
-
53749092893
-
The influenza virus M2 protein cytoplasmic tail interacts with the M1 protein and influences virus assembly at the site of virus budding
-
Chen BJ, Leser GP, Jackson D, Lamb RA. 2008. The influenza virus M2 protein cytoplasmic tail interacts with the M1 protein and influences virus assembly at the site of virus budding. J Virol 82:10059-10070. http://dx.doi.org/10.1128/JVI.01184-08.
-
(2008)
J Virol
, vol.82
, pp. 10059-10070
-
-
Chen, B.J.1
Leser, G.P.2
Jackson, D.3
Lamb, R.A.4
-
17
-
-
77951437276
-
Influenza virus M2 ion channel protein is necessary for filamentous virion formation
-
Rossman JS, Jing X, Leser GP, Balannik V, Pinto LH, Lamb RA. 2010. Influenza virus M2 ion channel protein is necessary for filamentous virion formation. J Virol 84:5078-5088. http://dx.doi.org/10.1128/JVI.00119-10.
-
(2010)
J Virol
, vol.84
, pp. 5078-5088
-
-
Rossman, J.S.1
Jing, X.2
Leser, G.P.3
Balannik, V.4
Pinto, L.H.5
Lamb, R.A.6
-
18
-
-
77957688042
-
A mutation in the receptor binding site enhances infectivity of 2009 H1N1 influenza hemagglutinin pseudotypes without changing antigenicity
-
Wang W, Castelán-Vega JA, Jiménez-Alberto A, Vassell R, Ye Z, Weiss CD. 2010. A mutation in the receptor binding site enhances infectivity of 2009 H1N1 influenza hemagglutinin pseudotypes without changing antigenicity. Virology 407:374-380. http://dx.doi.org/10.1016/j.virol.2010.08.027.
-
(2010)
Virology
, vol.407
, pp. 374-380
-
-
Wang, W.1
Castelán-Vega, J.A.2
Jiménez-Alberto, A.3
Vassell, R.4
Ye, Z.5
Weiss, C.D.6
-
19
-
-
79952702297
-
Antigenic stability of H1N1 pandemic vaccines correlates with vaccine strain
-
Farnsworth A, Cyr TD, Li C, Wang J, Li X. 2011. Antigenic stability of H1N1 pandemic vaccines correlates with vaccine strain. Vaccine 29:1529-1533. http://dx.doi.org/10.1016/j.vaccine.2010.12.120.
-
(2011)
Vaccine
, vol.29
, pp. 1529-1533
-
-
Farnsworth, A.1
Cyr, T.D.2
Li, C.3
Wang, J.4
Li, X.5
-
20
-
-
84867898126
-
Pandemic influenza vaccine: characterization of A/California/07/2009 (H1N1) recombinant hemagglutinin protein and insights into H1N1 antigen stability
-
Feshchenko E, Rhodes DG, Felberbaum R, McPherson C, Rininger JA, Post P, Cox MM. 2012. Pandemic influenza vaccine: characterization of A/California/07/2009 (H1N1) recombinant hemagglutinin protein and insights into H1N1 antigen stability. BMC Biotechnol 12:77. http://dx.doi.org/10.1186/1472-6750-12-77.
-
(2012)
BMC Biotechnol
, vol.12
, pp. 77
-
-
Feshchenko, E.1
Rhodes, D.G.2
Felberbaum, R.3
McPherson, C.4
Rininger, J.A.5
Post, P.6
Cox, M.M.7
-
21
-
-
84897557489
-
Structural stability of influenza A(H1N1)pdm09 virus hemagglutinins
-
Yang H, Chang JC, Guo Z, Carney PJ, Shore DA, Donis RO, Cox NJ, Villanueva JM, Klimov AI, Stevens J. 2014. Structural stability of influenza A(H1N1)pdm09 virus hemagglutinins. J Virol 88:4828-4838. http://dx.doi.org/10.1128/JVI.02278-13.
-
(2014)
J Virol
, vol.88
, pp. 4828-4838
-
-
Yang, H.1
Chang, J.C.2
Guo, Z.3
Carney, P.J.4
Shore, D.A.5
Donis, R.O.6
Cox, N.J.7
Villanueva, J.M.8
Klimov, A.I.9
Stevens, J.10
-
22
-
-
79959842089
-
Cross-neutralizing antibodies to pandemic 2009 H1N1 and recent seasonal H1N1 influenza A strains influenced by a mutation in hemagglutinin subunit 2
-
Wang W, Anderson CM, De Feo CJ, Zhuang M, Yang H, Vassell R, Xie H, Ye Z, Scott D, Weiss CD. 2011. Cross-neutralizing antibodies to pandemic 2009 H1N1 and recent seasonal H1N1 influenza A strains influenced by a mutation in hemagglutinin subunit 2. PLoS Pathog 7:e1002081. http://dx.doi.org/10.1371/journal.ppat.1002081.
-
(2011)
PLoS Pathog
, vol.7
-
-
Wang, W.1
Anderson, C.M.2
De Feo, C.J.3
Zhuang, M.4
Yang, H.5
Vassell, R.6
Xie, H.7
Ye, Z.8
Scott, D.9
Weiss, C.D.10
-
23
-
-
0030819379
-
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
-
Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D. 1997. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat Biotechnol 15:871-875. http://dx.doi.org/10.1038/nbt0997-871.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 871-875
-
-
Zufferey, R.1
Nagy, D.2
Mandel, R.J.3
Naldini, L.4
Trono, D.5
-
24
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini L, Blömer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D. 1996. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272:263-267. http://dx.doi.org/10.1126/science.272.5259.263.
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blömer, U.2
Gallay, P.3
Ory, D.4
Mulligan, R.5
Gage, F.H.6
Verma, I.M.7
Trono, D.8
-
25
-
-
84862909153
-
Selection with a peptide fusion inhibitor corresponding to the first heptad repeat of HIV-1 gp41 identifies two genetic pathways conferring cross-resistance to peptide fusion inhibitors corresponding to the first and second heptad repeats (HR1 and HR2) of gp41
-
Wang W, De Feo CJ, Zhuang M, Vassell R, Weiss CD. 2011. Selection with a peptide fusion inhibitor corresponding to the first heptad repeat of HIV-1 gp41 identifies two genetic pathways conferring cross-resistance to peptide fusion inhibitors corresponding to the first and second heptad repeats (HR1 and HR2) of gp41. J Virol 85:12929-12938. http://dx.doi.org/10.1128/JVI.05391-11.
-
(2011)
J Virol
, vol.85
, pp. 12929-12938
-
-
Wang, W.1
De Feo, C.J.2
Zhuang, M.3
Vassell, R.4
Weiss, C.D.5
-
26
-
-
20444477097
-
Cell signaling through the protein kinases cAMP-dependent protein kinase, protein kinase Cepsilon, and RAF-1 regulates amphotropic murine leukemia virus envelope protein-induced syncytium formation
-
Wang W, Jobbagy Z, Bird TH, Eiden MV, Anderson WB. 2005. Cell signaling through the protein kinases cAMP-dependent protein kinase, protein kinase Cepsilon, and RAF-1 regulates amphotropic murine leukemia virus envelope protein-induced syncytium formation. J Biol Chem 280:16772-16783. http://dx.doi.org/10.1074/jbc.M411537200.
-
(2005)
J Biol Chem
, vol.280
, pp. 16772-16783
-
-
Wang, W.1
Jobbagy, Z.2
Bird, T.H.3
Eiden, M.V.4
Anderson, W.B.5
-
27
-
-
1142287424
-
Ligand-modified vesicular stomatitis virus glycoprotein displays a temperature-sensitive intracellular trafficking and virus assembly phenotype
-
Guibinga GH, Hall FL, Gordon EM, Ruoslahti E, Friedmann T. 2004. Ligand-modified vesicular stomatitis virus glycoprotein displays a temperature-sensitive intracellular trafficking and virus assembly phenotype. Mol Ther 9:76-84. http://dx.doi.org/10.1016/j.ymthe.2003.09.018.
-
(2004)
Mol Ther
, vol.9
, pp. 76-84
-
-
Guibinga, G.H.1
Hall, F.L.2
Gordon, E.M.3
Ruoslahti, E.4
Friedmann, T.5
-
28
-
-
1342300737
-
Alphacomplementation assay for HIV envelope glycoprotein-mediated fusion
-
Holland AU, Munk C, Lucero GR, Nguyen LD, Landau NR. 2004. Alphacomplementation assay for HIV envelope glycoprotein-mediated fusion. Virology 319:343-352. http://dx.doi.org/10.1016/j.virol.2003.11.012.
-
(2004)
Virology
, vol.319
, pp. 343-352
-
-
Holland, A.U.1
Munk, C.2
Lucero, G.R.3
Nguyen, L.D.4
Landau, N.R.5
-
29
-
-
84876495377
-
Neutralizing and protective epitopes of the 2009 pandemic influenza H1N1 hemagglutinin
-
Schmeisser F, Friedman R, Besho J, Lugovtsev V, Soto J, Wang W, Weiss C, Williams O, Xie H, Ye Z, Weir JP. 2013. Neutralizing and protective epitopes of the 2009 pandemic influenza H1N1 hemagglutinin. Influenza Other Respir Viruses 7:480-490. http://dx.doi.org/10.1111/irv.12029.
-
(2013)
Influenza Other Respir Viruses
, vol.7
, pp. 480-490
-
-
Schmeisser, F.1
Friedman, R.2
Besho, J.3
Lugovtsev, V.4
Soto, J.5
Wang, W.6
Weiss, C.7
Williams, O.8
Xie, H.9
Ye, Z.10
Weir, J.P.11
-
30
-
-
53049089447
-
Establishment of retroviral pseudotypes with influenza hemagglutinins from H1, H3, and H5 subtypes for sensitive and specific detection of neutralizing antibodies
-
Wang W, Butler EN, Veguilla V, Vassell R, Thomas JT, Moos M, Jr, Ye Z, Hancock K, Weiss CD. 2008. Establishment of retroviral pseudotypes with influenza hemagglutinins from H1, H3, and H5 subtypes for sensitive and specific detection of neutralizing antibodies. J Virol Methods 153: 111-119. http://dx.doi.org/10.1016/j.jviromet.2008.07.015.
-
(2008)
J Virol Methods
, vol.153
, pp. 111-119
-
-
Wang, W.1
Butler, E.N.2
Veguilla, V.3
Vassell, R.4
Thomas, J.T.5
Moos Jr., M.6
Ye, Z.7
Hancock, K.8
Weiss, C.D.9
-
31
-
-
0030738524
-
Monitoring protein-protein interactions in intact eukaryotic cells by beta-galactosidase complementation
-
Rossi F, Charlton CA, Blau HM. 1997. Monitoring protein-protein interactions in intact eukaryotic cells by beta-galactosidase complementation. Proc Natl Acad Sci USA 94:8405-8410. http://dx.doi.org/10.1073/pnas.94.16.8405.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8405-8410
-
-
Rossi, F.1
Charlton, C.A.2
Blau, H.M.3
-
32
-
-
0020035202
-
Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion
-
Skehel JJ, Bayley PM, Brown EB, Martin SR, Waterfield MD, White JM, Wilson IA, Wiley DC. 1982. Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion. Proc Natl Acad Sci USA 79:968-972. http://dx.doi.org/10.1073/pnas.79.4.968.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 968-972
-
-
Skehel, J.J.1
Bayley, P.M.2
Brown, E.B.3
Martin, S.R.4
Waterfield, M.D.5
White, J.M.6
Wilson, I.A.7
Wiley, D.C.8
-
33
-
-
0021750873
-
Changes in the morphology of influenza particles induced at low pH
-
Ruigrok RW, Cremers AF, Beyer WE, de Ronde-Verloop FM. 1984. Changes in the morphology of influenza particles induced at low pH. Arch Virol 82:181-194. http://dx.doi.org/10.1007/BF01311162.
-
(1984)
Arch Virol
, vol.82
, pp. 181-194
-
-
Ruigrok, R.W.1
Cremers, A.F.2
Beyer, W.E.3
de Ronde-Verloop, F.M.4
-
34
-
-
0023403269
-
The influenza hemagglutinin precursor as an acid-sensitive probe of the biosynthetic pathway
-
Boulay F, Doms RW, Wilson I, Helenius A. 1987. The influenza hemagglutinin precursor as an acid-sensitive probe of the biosynthetic pathway. EMBO J 6:2643-2650.
-
(1987)
EMBO J
, vol.6
, pp. 2643-2650
-
-
Boulay, F.1
Doms, R.W.2
Wilson, I.3
Helenius, A.4
-
35
-
-
0031460632
-
Influenza hemagglutinin is springloaded by a metastable native conformation
-
Carr CM, Chaudhry C, Kim PS. 1997. Influenza hemagglutinin is springloaded by a metastable native conformation. Proc Natl Acad Sci USA 94:14306-14313. http://dx.doi.org/10.1073/pnas.94.26.14306.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14306-14313
-
-
Carr, C.M.1
Chaudhry, C.2
Kim, P.S.3
-
36
-
-
77950840696
-
Novel inhibitors of influenza virus fusion: structure-activity relationship and interaction with the viral hemagglutinin
-
Vanderlinden E, Goktas F, Cesur Z, Froeyen M, Reed ML, Russell CJ, Cesur N, Naesens L. 2010. Novel inhibitors of influenza virus fusion: structure-activity relationship and interaction with the viral hemagglutinin. J Virol 84:4277-4288. http://dx.doi.org/10.1128/JVI.02325-09.
-
(2010)
J Virol
, vol.84
, pp. 4277-4288
-
-
Vanderlinden, E.1
Goktas, F.2
Cesur, Z.3
Froeyen, M.4
Reed, M.L.5
Russell, C.J.6
Cesur, N.7
Naesens, L.8
-
37
-
-
79955373167
-
Structural characterization of an early fusion intermediate of influenza virus hemagglutinin
-
Xu R, Wilson IA. 2011. Structural characterization of an early fusion intermediate of influenza virus hemagglutinin. J Virol 85:5172-5182. http://dx.doi.org/10.1128/JVI.02430-10.
-
(2011)
J Virol
, vol.85
, pp. 5172-5182
-
-
Xu, R.1
Wilson, I.A.2
-
38
-
-
68949192806
-
Influenza virus morphogenesis and budding
-
Nayak DP, Balogun RA, Yamada H, Zhou ZH, Barman S. 2009. Influenza virus morphogenesis and budding. Virus Res 143:147-161. http://dx.doi.org/10.1016/j.virusres.2009.05.010.
-
(2009)
Virus Res
, vol.143
, pp. 147-161
-
-
Nayak, D.P.1
Balogun, R.A.2
Yamada, H.3
Zhou, Z.H.4
Barman, S.5
-
39
-
-
33646718791
-
The cytoplasmic tail of the influenza A virus M2 protein plays a role in viral assembly
-
Iwatsuki-Horimoto K, Horimoto T, Noda T, Kiso M, Maeda J, Watanabe S, Muramoto Y, Fujii K, Kawaoka Y. 2006. The cytoplasmic tail of the influenza A virus M2 protein plays a role in viral assembly. J Virol 80:5233-5240. http://dx.doi.org/10.1128/JVI.00049-06.
-
(2006)
J Virol
, vol.80
, pp. 5233-5240
-
-
Iwatsuki-Horimoto, K.1
Horimoto, T.2
Noda, T.3
Kiso, M.4
Maeda, J.5
Watanabe, S.6
Muramoto, Y.7
Fujii, K.8
Kawaoka, Y.9
-
40
-
-
0028181687
-
Influenza A virus M2 ion channel protein: a structure-function analysis
-
Holsinger LJ, Nichani D, Pinto L, Lamb RA. 1994. Influenza A virus M2 ion channel protein: a structure-function analysis. J Virol 68:1551-1563.
-
(1994)
J Virol
, vol.68
, pp. 1551-1563
-
-
Holsinger, L.J.1
Nichani, D.2
Pinto, L.3
Lamb, R.A.4
-
41
-
-
0027185716
-
Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block
-
Wang C, Takeuchi K, Pinto LH, Lamb RA. 1993. Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block. J Virol 67:5585-5594.
-
(1993)
J Virol
, vol.67
, pp. 5585-5594
-
-
Wang, C.1
Takeuchi, K.2
Pinto, L.H.3
Lamb, R.A.4
-
42
-
-
38749106195
-
Structure and mechanism of the M2 proton channel of influenza A virus
-
Schnell JR, Chou JJ. 2008. Structure and mechanism of the M2 proton channel of influenza A virus. Nature 451:591-595. http://dx.doi.org/10.1038/nature06531.
-
(2008)
Nature
, vol.451
, pp. 591-595
-
-
Schnell, J.R.1
Chou, J.J.2
-
43
-
-
77956996035
-
Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus
-
Acharya R, Carnevale V, Fiorin G, Levine BG, Polishchuk AL, Balannik V, Samish I, Lamb RA, Pinto LH, DeGrado WF, Klein ML. 2010. Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus. Proc Natl Acad Sci USA 107: 15075-15080. http://dx.doi.org/10.1073/pnas.1007071107.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15075-15080
-
-
Acharya, R.1
Carnevale, V.2
Fiorin, G.3
Levine, B.G.4
Polishchuk, A.L.5
Balannik, V.6
Samish, I.7
Lamb, R.A.8
Pinto, L.H.9
DeGrado, W.F.10
Klein, M.L.11
-
44
-
-
38749151911
-
Structural basis for the function and inhibition of an influenza virus proton channel
-
Stouffer AL, Acharya R, Salom D, Levine AS, Di Costanzo L, Soto CS, Tereshko V, Nanda V, Stayrook S, DeGrado WF. 2008. Structural basis for the function and inhibition of an influenza virus proton channel. Nature 451:596-599. http://dx.doi.org/10.1038/nature06528.
-
(2008)
Nature
, vol.451
, pp. 596-599
-
-
Stouffer, A.L.1
Acharya, R.2
Salom, D.3
Levine, A.S.4
Di Costanzo, L.5
Soto, C.S.6
Tereshko, V.7
Nanda, V.8
Stayrook, S.9
DeGrado, W.F.10
-
45
-
-
78650290518
-
Resistance characteristics of influenza to amino-adamantyls
-
Astrahan P, Arkin IT. 2011. Resistance characteristics of influenza to amino-adamantyls. Biochim Biophys Acta 1808:547-553. http://dx.doi.org/10.1016/j.bbamem.2010.06.018.
-
(2011)
Biochim Biophys Acta
, vol.1808
, pp. 547-553
-
-
Astrahan, P.1
Arkin, I.T.2
-
46
-
-
75149171465
-
Functional studies and modeling of porelining residue mutants of the influenza A virus M2 ion channel
-
Balannik V, Carnevale V, Fiorin G, Levine BG, Lamb RA, Klein ML, Degrado WF, Pinto LH. 2010. Functional studies and modeling of porelining residue mutants of the influenza A virus M2 ion channel. Biochemistry 49:696-708. http://dx.doi.org/10.1021/bi901799k.
-
(2010)
Biochemistry
, vol.49
, pp. 696-708
-
-
Balannik, V.1
Carnevale, V.2
Fiorin, G.3
Levine, B.G.4
Lamb, R.A.5
Klein, M.L.6
Degrado, W.F.7
Pinto, L.H.8
-
47
-
-
84902455679
-
Aminoadamantanes with persistent in vitro efficacy against H1N1 (2009) influenza A
-
Kolocouris A, Tzitzoglaki C, Johnson FB, Zell R, Wright AK, Cross TA, Tietjen I, Fedida D, Busath DD. 2014. Aminoadamantanes with persistent in vitro efficacy against H1N1 (2009) influenza A. J Med Chem 57: 4629-4639. http://dx.doi.org/10.1021/jm500598u.
-
(2014)
J Med Chem
, vol.57
, pp. 4629-4639
-
-
Kolocouris, A.1
Tzitzoglaki, C.2
Johnson, F.B.3
Zell, R.4
Wright, A.K.5
Cross, T.A.6
Tietjen, I.7
Fedida, D.8
Busath, D.D.9
-
48
-
-
12944314951
-
Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations
-
Abed Y, Goyette N, Boivin G. 2005. Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations. Antimicrob Agents Chemother 49:556-559. http://dx.doi.org/10.1128/AAC.49.2.556-559.2005.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 556-559
-
-
Abed, Y.1
Goyette, N.2
Boivin, G.3
-
49
-
-
53249142257
-
Adamantane resistance in influenza A(H1) viruses increased in 2007 in South East Asia but decreased in Australia and some other countries
-
Barr IG, Deng YM, Iannello P, Hurt AC, Komadina N. 2008. Adamantane resistance in influenza A(H1) viruses increased in 2007 in South East Asia but decreased in Australia and some other countries. Antiviral Res 80:200-205. http://dx.doi.org/10.1016/j.antiviral.2008.06.008.
-
(2008)
Antiviral Res
, vol.80
, pp. 200-205
-
-
Barr, I.G.1
Deng, Y.M.2
Iannello, P.3
Hurt, A.C.4
Komadina, N.5
-
50
-
-
34447271704
-
Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide
-
Deyde VM, Xu X, Bright RA, Shaw M, Smith CB, Zhang Y, Shu Y, Gubareva LV, Cox NJ, Klimov AI. 2007. Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide. J Infect Dis 196:249-257. http://dx.doi.org/10.1086/518936.
-
(2007)
J Infect Dis
, vol.196
, pp. 249-257
-
-
Deyde, V.M.1
Xu, X.2
Bright, R.A.3
Shaw, M.4
Smith, C.B.5
Zhang, Y.6
Shu, Y.7
Gubareva, L.V.8
Cox, N.J.9
Klimov, A.I.10
-
51
-
-
40049108736
-
Increased incidence of adamantane-resistant influenza A(H1N1) and A(H3N2) viruses during the 2006-2007 influenza season in Japan
-
Saito R, Suzuki Y, Li D, Zaraket H, Sato I, Masaki H, Kawashima T, Hibi S, Sano Y, Shobugawa Y, Oguma T, Suzuki H. 2008. Increased incidence of adamantane-resistant influenza A(H1N1) and A(H3N2) viruses during the 2006-2007 influenza season in Japan. J Infect Dis 197: 630-632. http://dx.doi.org/10.1086/525055.
-
(2008)
J Infect Dis
, vol.197
, pp. 630-632
-
-
Saito, R.1
Suzuki, Y.2
Li, D.3
Zaraket, H.4
Sato, I.5
Masaki, H.6
Kawashima, T.7
Hibi, S.8
Sano, Y.9
Shobugawa, Y.10
Oguma, T.11
Suzuki, H.12
-
52
-
-
0037951723
-
Frequency of amantadine-resistant influenzaAviruses during two seasons featuring cocirculation of H1N1 and H3N2
-
Saito R, Sakai T, Sato I, Sano Y, Oshitani H, Sato M, Suzuki H. 2003. Frequency of amantadine-resistant influenzaAviruses during two seasons featuring cocirculation of H1N1 and H3N2. J Clin Microbiol 41:2164-2165. http://dx.doi.org/10.1128/JCM.41.5.2164-2165.2003.
-
(2003)
J Clin Microbiol
, vol.41
, pp. 2164-2165
-
-
Saito, R.1
Sakai, T.2
Sato, I.3
Sano, Y.4
Oshitani, H.5
Sato, M.6
Suzuki, H.7
-
53
-
-
67449100802
-
Oseltamivir-and amantadine-resistant influenza viruses A (H1N1)
-
Cheng PK, Leung TW, Ho EC, Leung PC, Ng AY, Lai MY, Lim WW. 2009. Oseltamivir-and amantadine-resistant influenza viruses A (H1N1). Emerg Infect Dis 15:966-968. http://dx.doi.org/10.3201/eid1506.081357.
-
(2009)
Emerg Infect Dis
, vol.15
, pp. 966-968
-
-
Cheng, P.K.1
Leung, T.W.2
Ho, E.C.3
Leung, P.C.4
Ng, A.Y.5
Lai, M.Y.6
Lim, W.W.7
-
54
-
-
77953473847
-
Quantitative thin-layer chromatographic method for determination of amantadine hydrochloride
-
Askal HF, Khedr AS, Darwish IA, Mahmoud RM. 2008. Quantitative thin-layer chromatographic method for determination of amantadine hydrochloride. Int J Biomed Sci 4:155-160.
-
(2008)
Int J Biomed Sci
, vol.4
, pp. 155-160
-
-
Askal, H.F.1
Khedr, A.S.2
Darwish, I.A.3
Mahmoud, R.M.4
-
55
-
-
49449093199
-
Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel
-
Jing X, Ma C, Ohigashi Y, Oliveira FA, Jardetzky TS, Pinto LH, Lamb RA. 2008. Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel. Proc Natl Acad SciUS A 105:10967-10972. http://dx.doi.org/10.1073/pnas.0804958105.
-
(2008)
Proc Natl Acad SciUS A
, vol.105
, pp. 10967-10972
-
-
Jing, X.1
Ma, C.2
Ohigashi, Y.3
Oliveira, F.A.4
Jardetzky, T.S.5
Pinto, L.H.6
Lamb, R.A.7
-
56
-
-
46049110693
-
The interplay of functional tuning, drug resistance, and thermodynamic stability in the evolution of the M2 proton channel from the influenza A virus
-
Stouffer AL, Ma C, Cristian L, Ohigashi Y, Lamb RA, Lear JD, Pinto LH, DeGrado WF. 2008. The interplay of functional tuning, drug resistance, and thermodynamic stability in the evolution of the M2 proton channel from the influenza A virus. Structure 16:1067-1076. http://dx.doi.org/10.1016/j.str.2008.04.011.
-
(2008)
Structure
, vol.16
, pp. 1067-1076
-
-
Stouffer, A.L.1
Ma, C.2
Cristian, L.3
Ohigashi, Y.4
Lamb, R.A.5
Lear, J.D.6
Pinto, L.H.7
DeGrado, W.F.8
-
57
-
-
77951983109
-
Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors
-
Böttcher-Friebertshäuser E, Freuer C, Sielaff F, Schmidt S, Eickmann M, Uhlendorff J, Steinmetzer T, Klenk HD, Garten W. 2010. Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors. J Virol 84:5605-5614. http://dx.doi.org/10.1128/JVI.00140-10.
-
(2010)
J Virol
, vol.84
, pp. 5605-5614
-
-
Böttcher-Friebertshäuser, E.1
Freuer, C.2
Sielaff, F.3
Schmidt, S.4
Eickmann, M.5
Uhlendorff, J.6
Steinmetzer, T.7
Klenk, H.D.8
Garten, W.9
-
58
-
-
84874761652
-
Influenza HA subtypes demonstrate divergent phenotypes for cleavage activation and pH of fusion: implications for host range and adaptation
-
Galloway SE, Reed ML, Russell CJ, Steinhauer DA. 2013. Influenza HA subtypes demonstrate divergent phenotypes for cleavage activation and pH of fusion: implications for host range and adaptation. PLoS Pathog 9:e1003151. http://dx.doi.org/10.1371/journal.ppat.1003151.
-
(2013)
PLoS Pathog
, vol.9
-
-
Galloway, S.E.1
Reed, M.L.2
Russell, C.J.3
Steinhauer, D.A.4
-
59
-
-
84857067845
-
Enhanced growth of influenza vaccine seed viruses in Vero cells mediated by broadening the optimal pH range for virus membrane fusion
-
Murakami S, Horimoto T, Ito M, Takano R, Katsura H, Shimojima M, Kawaoka Y. 2012. Enhanced growth of influenza vaccine seed viruses in Vero cells mediated by broadening the optimal pH range for virus membrane fusion. J Virol 86:1405-1410. http://dx.doi.org/10.1128/JVI.06009-11.
-
(2012)
J Virol
, vol.86
, pp. 1405-1410
-
-
Murakami, S.1
Horimoto, T.2
Ito, M.3
Takano, R.4
Katsura, H.5
Shimojima, M.6
Kawaoka, Y.7
-
60
-
-
84893787458
-
A single amino acid in the stalk region of the H1N1pdm influenza virusHAprotein affects viral fusion, stability and infectivity
-
Cotter CR, Jin H, Chen Z. 2014. A single amino acid in the stalk region of the H1N1pdm influenza virusHAprotein affects viral fusion, stability and infectivity. PLoS Pathog 10:e1003831. http://dx.doi.org/10.1371/journal.ppat.1003831.
-
(2014)
PLoS Pathog
, vol.10
-
-
Cotter, C.R.1
Jin, H.2
Chen, Z.3
-
61
-
-
79954993737
-
Mutations affecting the stability of the haemagglutinin molecule impair the immunogenicity of live attenuated H3N2 intranasal influenza vaccine candidates lacking NS1
-
Nakowitsch S, Wolschek M, Morokutti A, Ruthsatz T, Krenn BM, Ferko B, Ferstl N, Triendl A, Muster T, Egorov A, Romanova J. 2011. Mutations affecting the stability of the haemagglutinin molecule impair the immunogenicity of live attenuated H3N2 intranasal influenza vaccine candidates lacking NS1. Vaccine 29:3517-3524. http://dx.doi.org/10.1016/j.vaccine.2011.02.100.
-
(2011)
Vaccine
, vol.29
, pp. 3517-3524
-
-
Nakowitsch, S.1
Wolschek, M.2
Morokutti, A.3
Ruthsatz, T.4
Krenn, B.M.5
Ferko, B.6
Ferstl, N.7
Triendl, A.8
Muster, T.9
Egorov, A.10
Romanova, J.11
-
62
-
-
84897609583
-
Egg-or cell culture-derived hemagglutinin mutations impair virus stability and antigen content of inactivated influenza vaccines
-
Nakowitsch S, Waltenberger AM, Wressnigg N, Ferstl N, Triendl A, Kiefmann B, Montomoli E, Lapini G, Sergeeva M, Muster T, Romanova JR. 2014. Egg-or cell culture-derived hemagglutinin mutations impair virus stability and antigen content of inactivated influenza vaccines. Biotechnol J 9:405-414. http://dx.doi.org/10.1002/biot.201300225.
-
(2014)
Biotechnol J
, vol.9
, pp. 405-414
-
-
Nakowitsch, S.1
Waltenberger, A.M.2
Wressnigg, N.3
Ferstl, N.4
Triendl, A.5
Kiefmann, B.6
Montomoli, E.7
Lapini, G.8
Sergeeva, M.9
Muster, T.10
Romanova, J.R.11
-
63
-
-
0007600773
-
Adaptation of egg-grown and transfectant influenza viruses for growth in mammalian cells: selection of hemagglutinin mutants with elevated pH of membrane fusion
-
Lin YP, Wharton SA, Martin J, Skehel JJ, Wiley DC, Steinhauer DA. 1997. Adaptation of egg-grown and transfectant influenza viruses for growth in mammalian cells: selection of hemagglutinin mutants with elevated pH of membrane fusion. Virology 233:402-410. http://dx.doi.org/10.1006/viro.1997.8626.
-
(1997)
Virology
, vol.233
, pp. 402-410
-
-
Lin, Y.P.1
Wharton, S.A.2
Martin, J.3
Skehel, J.J.4
Wiley, D.C.5
Steinhauer, D.A.6
-
64
-
-
79954514108
-
Single HA2 mutation increases the infectivity and immunogenicity of a live attenuated H5N1 intranasal influenza vaccine candidate lacking NS1
-
Krenn BM, Egorov A, Romanovskaya-Romanko E, Wolschek M, Nakowitsch S, Ruthsatz T, Kiefmann B, Morokutti A, Humer J, Geiler J, Cinatl J, Michaelis M, Wressnigg N, Sturlan S, Ferko B, Batishchev OV, Indenbom AV, Zhu R, Kastner M, Hinterdorfer P, Kiselev O, Muster T, Romanova J. 2011. Single HA2 mutation increases the infectivity and immunogenicity of a live attenuated H5N1 intranasal influenza vaccine candidate lacking NS1. PLoS One 6:e18577. http://dx.doi.org/10.1371/journal.pone.0018577.
-
(2011)
PLoS One
, vol.6
-
-
Krenn, B.M.1
Egorov, A.2
Romanovskaya-Romanko, E.3
Wolschek, M.4
Nakowitsch, S.5
Ruthsatz, T.6
Kiefmann, B.7
Morokutti, A.8
Humer, J.9
Geiler, J.10
Cinatl, J.11
Michaelis, M.12
Wressnigg, N.13
Sturlan, S.14
Ferko, B.15
Batishchev, O.V.16
Indenbom, A.V.17
Zhu, R.18
Kastner, M.19
Hinterdorfer, P.20
Kiselev, O.21
Muster, T.22
Romanova, J.23
more..
-
65
-
-
64049092310
-
Amino acid residues in the fusion peptide pocket regulate the pH of activation of the H5N1 influenza virus hemagglutinin protein
-
Reed ML, Yen HL, DuBois RM, Bridges OA, Salomon R, Webster RG, Russell CJ. 2009. Amino acid residues in the fusion peptide pocket regulate the pH of activation of the H5N1 influenza virus hemagglutinin protein. J Virol 83:3568-3580. http://dx.doi.org/10.1128/JVI.02238-08.
-
(2009)
J Virol
, vol.83
, pp. 3568-3580
-
-
Reed, M.L.1
Yen, H.L.2
DuBois, R.M.3
Bridges, O.A.4
Salomon, R.5
Webster, R.G.6
Russell, C.J.7
-
66
-
-
73949160128
-
The pH of activation of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity and transmissibility in ducks
-
Reed ML, Bridges OA, Seiler P, Kim JK, Yen HL, Salomon R, Govorkova EA, Webster RG, Russell CJ. 2010. The pH of activation of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity and transmissibility in ducks. J Virol 84:1527-1535. http://dx.doi.org/10.1128/JVI.02069-09.
-
(2010)
J Virol
, vol.84
, pp. 1527-1535
-
-
Reed, M.L.1
Bridges, O.A.2
Seiler, P.3
Kim, J.K.4
Yen, H.L.5
Salomon, R.6
Govorkova, E.A.7
Webster, R.G.8
Russell, C.J.9
-
67
-
-
30344461926
-
Comparison of in vitro replication features of H7N3 influenza viruses from wild ducks and turkeys: potential implications for interspecies transmission
-
Giannecchini S, Campitelli L, Calzoletti L, De Marco MA, Azzi A, Donatelli I. 2006. Comparison of in vitro replication features of H7N3 influenza viruses from wild ducks and turkeys: potential implications for interspecies transmission. J Gen Virol 87:171-175. http://dx.doi.org/10.1099/vir.0.81187-0.
-
(2006)
J Gen Virol
, vol.87
, pp. 171-175
-
-
Giannecchini, S.1
Campitelli, L.2
Calzoletti, L.3
De Marco, M.A.4
Azzi, A.5
Donatelli, I.6
-
68
-
-
84861394598
-
Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets
-
Imai M, Watanabe T, Hatta M, Das SC, Ozawa M, Shinya K, Zhong G, Hanson A, Katsura H, Watanabe S, Li C, Kawakami E, Yamada S, Kiso M, Suzuki Y, Maher EA, Neumann G, Kawaoka Y. 2012. Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets. Nature 486:420-428. http://dx.doi.org/10.1038/nature10831.
-
(2012)
Nature
, vol.486
, pp. 420-428
-
-
Imai, M.1
Watanabe, T.2
Hatta, M.3
Das, S.C.4
Ozawa, M.5
Shinya, K.6
Zhong, G.7
Hanson, A.8
Katsura, H.9
Watanabe, S.10
Li, C.11
Kawakami, E.12
Yamada, S.13
Kiso, M.14
Suzuki, Y.15
Maher, E.A.16
Neumann, G.17
Kawaoka, Y.18
-
69
-
-
84862618108
-
Airborne transmission of influenza A/H5N1 virus between ferrets
-
Herfst S, Schrauwen EJ, Linster M, Chutinimitkul S, de Wit E, Munster VJ, Sorrell EM, Bestebroer TM, Burke DF, Smith DJ, Rimmelzwaan GF, Osterhaus AD, Fouchier RA. 2012. Airborne transmission of influenza A/H5N1 virus between ferrets. Science 336:1534-1541. http://dx.doi.org/10.1126/science.1213362.
-
(2012)
Science
, vol.336
, pp. 1534-1541
-
-
Herfst, S.1
Schrauwen, E.J.2
Linster, M.3
Chutinimitkul, S.4
de Wit, E.5
Munster, V.J.6
Sorrell, E.M.7
Bestebroer, T.M.8
Burke, D.F.9
Smith, D.J.10
Rimmelzwaan, G.F.11
Osterhaus, A.D.12
Fouchier, R.A.13
-
70
-
-
84907977986
-
The matrix gene segment destabilizes the acid and thermal stability of the hemagglutinin of pandemic live attenuated influenza virus vaccines
-
O'Donnell CD, Vogel L, Matsuoka Y, Jin H, Subbarao K. 2014. The matrix gene segment destabilizes the acid and thermal stability of the hemagglutinin of pandemic live attenuated influenza virus vaccines. J Virol 88:12374-12384. http://dx.doi.org/10.1128/JVI.01107-14.
-
(2014)
J Virol
, vol.88
, pp. 12374-12384
-
-
O'Donnell, C.D.1
Vogel, L.2
Matsuoka, Y.3
Jin, H.4
Subbarao, K.5
|