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Volumn 32, Issue 4, 2008, Pages 209-218

Plant sterols: Cardiovascular risk factors?;Pflanzliche Sterole: Risikofaktoren für kardiovaskuleire Erkrankungen?

Author keywords

campesterol; Campesterol; cholestanol; Cholestanol; Cholesterinabsorption; Cholesterinsenkung; Cholesterinstoffwechsel; Cholesterinsynthese; cholesterol absorption; cholesterol lowering; cholesterol metabolism; Functional Food; Lathosterol; Margarine; Pflanzliche Sterole; Sitosterol; Sitosterolaimie

Indexed keywords


EID: 84977925106     PISSN: 03423026     EISSN: 14390477     Source Type: Journal    
DOI: 10.1515/JLM.2008.040     Document Type: Article
Times cited : (8)

References (106)
  • 2
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group.
    • Shepherd, J, Cobbe, S.M., Ford, I, Isles, C.G., Lorimer, A.R., Mac Farlane, P.W., et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. N Engl J Med 1995;333:1301-7.
    • (1995) N Engl J Med , vol.333
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3    Isles, C.G.4    Lorimer, A.R.5    Mac Farlane, P.W.6
  • 5
    • 0037126526 scopus 로고    scopus 로고
    • National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III).
    • Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report.
    • National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002;106:3143-421.
    • (2002) Circulation , vol.106
  • 6
    • 0036403449 scopus 로고    scopus 로고
    • Phytosterols in human nutrition.
    • Ostlund, R.E. Jr. Phytosterols in human nutrition. Annu Rev Nutr 2002;22:533-49.
    • (2002) Annu Rev Nutr , vol.22
    • Ostlund, R.E.1
  • 7
    • 33947253738 scopus 로고
    • Reducton of blood cholesterol in man.
    • Pollak, O.J. Reducton of blood cholesterol in man. Circulation 1953;7:702-6.
    • (1953) Circulation , vol.7
    • Pollak, O.J.1
  • 8
    • 0034712522 scopus 로고    scopus 로고
    • Plant sterol and stanol margarines and health.
    • Law, M. Plant sterol and stanol margarines and health. Br Med J 2000;320:861-4.
    • (2000) Br Med J , vol.320
    • Law, M.1
  • 9
    • 34247154875 scopus 로고    scopus 로고
    • Regarding the potential perils of phytosterols.
    • Brendsel, J, Green, S.J., Regarding the potential perils of phytosterols. Atherosclerosis 2007;192:227-9.
    • (2007) Atherosclerosis , vol.192
    • Brendsel, J.1    Green, S.J.2
  • 10
    • 0003854857 scopus 로고    scopus 로고
    • FDA authorizes new coronary heart disease health claim for plant sterol and plant stanol esters. T00-40. Print Media: Ruth Welch, 202-205-4144; September 5, 2000; Consumer Inquiries 888-INFOFDA; Food and Drug Administration; US Department of Health and Human Services; 5600 Fisherslane Rockville MD 20857.
    • FDA Talk Paper. FDA authorizes new coronary heart disease health claim for plant sterol and plant stanol esters. T00-40. Print Media: Ruth Welch, 202-205-4144; September 5, 2000; Consumer Inquiries 888-INFOFDA; Food and Drug Administration; US Department of Health and Human Services; 5600 Fisherslane Rockville MD 20857.
    • FDA Talk Paper.
  • 11
    • 0036403449 scopus 로고    scopus 로고
    • Phytosterols in human nutrition.
    • Ostlund, R. Jr. Phytosterols in human nutrition. Annu Rev Nutr 2002;22:533-49.
    • (2002) Annu Rev Nutr , vol.22
    • Ostlund, R.1
  • 12
    • 0025156823 scopus 로고
    • Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population.
    • Miettinen, T.A., Tilvis, R.S., Kesämiemi, Y.A. Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population. Am J Epidemiol 1990;131:20–31.
    • (1990) Am J Epidemiol , vol.131 , pp. 20-31
    • Miettinen, T.A.1    Tilvis, R.S.2    Kesämiemi, Y.A.3
  • 13
    • 0024509148 scopus 로고
    • Serum cholestanol and plant sterol levels in relation to cholesterol metabolism in middle-aged men.
    • Miettinen, T.A., Tilvis, R.S., Kesaniemi, Y.A. Serum cholestanol and plant sterol levels in relation to cholesterol metabolism in middle-aged men. Metabolism 1989;38:136-40.
    • (1989) Metabolism , vol.38
    • Miettinen, T.A.1    Tilvis, R.S.2    Kesaniemi, Y.A.3
  • 15
    • 0031888994 scopus 로고    scopus 로고
    • Lipoprotein metabolism.
    • Beisiegel, U. Lipoprotein metabolism. Eur Heart J 1998; 19:A20-A23.
    • (1998) Eur Heart J , vol.19
    • Beisiegel, U.1
  • 17
    • 0030951706 scopus 로고    scopus 로고
    • Theoretical considerations of what regulates low-density lipoprotein cholesterol.
    • Dietschy, J.M. Theoretical considerations of what regulates low-density lipoprotein cholesterol. Am J Clin Nutr 1997; 65:1581-9.
    • (1997) Am J Clin Nutr , vol.65
    • Dietschy, J.M.1
  • 18
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway.
    • Goldstein, J.L., Brown, M.S. Regulation of the mevalonate pathway. Nature 1990;343:425-30.
    • (1990) Nature , vol.343
    • Goldstein, J.L.1    Brown, M.S.2
  • 19
    • 0025156823 scopus 로고
    • Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population.
    • Miettinen, T.A., Tilvis, R.S., Kesämiemi, Y.A. Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population. Am J Epidemiol 1990;131:20–31.
    • (1990) Am J Epidemiol , vol.131 , pp. 20-31
    • Miettinen, T.A.1    Tilvis, R.S.2    Kesämiemi, Y.A.3
  • 20
    • 21244465525 scopus 로고    scopus 로고
    • Cholesterol and plant sterol absorption: Recent insights.
    • von Bergmann, K, Sudhop, T, Lutjohann, D. Cholesterol and plant sterol absorption: Recent insights. Am J Cardiol 2005;96:10D-14.
    • (2005) Am J Cardiol , vol.96
    • von Bergmann, K.1    Sudhop, T.2    Lutjohann, D.3
  • 21
    • 7744236073 scopus 로고    scopus 로고
    • Cholesterol metabolism and its implications for theaapeutic interventions in patients with hypercholesterolaemia.
    • Gylling, H. Cholesterol metabolism and its implications for theaapeutic interventions in patients with hypercholesterolaemia. Int J Clin Pract 2004;58:859-66.
    • (2004) Int J Clin Pract , vol.58
    • Gylling, H.1
  • 22
    • 0141869052 scopus 로고    scopus 로고
    • Scavenger receptor class B type I (SR-BI) in pig enterocytes: trafficking from the brush border to lipid droplets during fat absorption.
    • Hansen, G.H., Niels-Christiansen, L.L., Immerdal, L, Danielsen, E.M. Scavenger receptor class B type I (SR-BI) in pig enterocytes: trafficking from the brush border to lipid droplets during fat absorption. Gut 2003;52:1424-31.
    • (2003) Gut , vol.52
    • Hansen, G.H.1    Niels-Christiansen, L.L.2    Immerdal, L.3    Danielsen, E.M.4
  • 23
    • 10744221008 scopus 로고    scopus 로고
    • Niemann-Pick C1 like 1 protein is critical for intestinal cholesterol absorption.
    • Altmann, S.W., Davis, H.R. Jr, Zhu, L.J., Yao, X, Hoos, L.M., Tetzloffm, G, et al. Niemann-Pick C1 like 1 protein is critical for intestinal cholesterol absorption. Science 2004;303:1424-31.
    • (2004) Science , vol.303
    • Altmann, S.W.1    Davis, H.R.2    Zhu, L.J.3    Yao, X.4    Hoos, L.M.5    Tetzloffm, G.6
  • 24
    • 0035158733 scopus 로고    scopus 로고
    • Identification of a gene, ABC G5, important in the regulation of dietary cholesterol absorption.
    • Lee, M.H., Lu, K, Hazard, S, Yu, H, Shulenin, S, Hidaka, H, et al. Identification of a gene, ABC G5, important in the regulation of dietary cholesterol absorption. Nat Genet 2001;27:79–83.
    • (2001) Nat Genet , vol.27 , pp. 79-83
    • Lee, M.H.1    Lu, K.2    Hazard, S.3    Yu, H.4    Shulenin, S.5    Hidaka, H.6
  • 25
    • 17744390348 scopus 로고    scopus 로고
    • Accumulation of dietary cholesterol in sitosterolaemia caused by mutations in adjacent ABC transporters.
    • Berge, K.E.,. Tian, H, Graf, G.A., Yu, L, Grishin, N.V., Schultz, J, et al. Accumulation of dietary cholesterol in sitosterolaemia caused by mutations in adjacent ABC transporters. Science 2000;290:1771-5.
    • (2000) Science , vol.290
    • Berge, K.E.1    Tian, H.2    Graf, G.A.3    Yu, L.4    Grishin, N.V.5    Schultz, J.6
  • 26
    • 0035491250 scopus 로고    scopus 로고
    • Mutations in ATP-cassette binding proteins G5( ABCG5) and G8(ABCG8) causing sitosterolaemia.
    • Hubacek, J.A., Berge, K.E., Cohen, J.C., Hobbs, H.H., Mutations in ATP-cassette binding proteins G5( ABCG5) and G8(ABCG8) causing sitosterolaemia. Hum Mutat 2001;18:359-60.
    • (2001) Hum Mutat , vol.18
    • Hubacek, J.A.1    Berge, K.E.2    Cohen, J.C.3    Hobbs, H.H.4
  • 27
    • 0032913411 scopus 로고    scopus 로고
    • Percent cholesterol absorption in normal women and men quantified with dual stable isotopic tracers and negative ion mass spectrometry.
    • Bosner, M.S., Lange, L.G.,. Stenson, W.F., Ostlund, R.E. Jr. Percent cholesterol absorption in normal women and men quantified with dual stable isotopic tracers and negative ion mass spectrometry. J Lipid Res 1999;40:302-8.
    • (1999) J Lipid Res , vol.40
    • Bosner, M.S.1    Lange, L.G.2    Stenson, W.F.3    Ostlund, R.E.4
  • 28
    • 0027729980 scopus 로고
    • Comparison of intestinal absorption of cholesterol with different plant sterols in man.
    • Heinemann, T, Axtmann, G, von Bergmann, K. Comparison of intestinal absorption of cholesterol with different plant sterols in man. Eur J Clin Invest 1993;23:827-31.
    • (1993) Eur J Clin Invest , vol.23
    • Heinemann, T.1    Axtmann, G.2    von Bergmann, K.3
  • 30
    • 0022574838 scopus 로고
    • Serum plant sterols and their relation to cholesterol absorption.
    • Tilvis, R.S., Miettinen, T.A. Serum plant sterols and their relation to cholesterol absorption. Am J Clin Nutr 1986;43:92-7.
    • (1986) Am J Clin Nutr , vol.43
    • Tilvis, R.S.1    Miettinen, T.A.2
  • 31
    • 0025325566 scopus 로고
    • Apparent lack of conversion of sitosterol into C24-bile acids in humans.
    • Boberg, K.M., Einarsson, K, Björkhem, I. Apparent lack of conversion of sitosterol into C24-bile acids in humans. J Lipid Res 1990;3:1083-8.
    • (1990) J Lipid Res , vol.3
    • Boberg, K.M.1    Einarsson, K.2    Björkhem, I.3
  • 32
    • 0036895134 scopus 로고    scopus 로고
    • Comparison of the hepatic clearances of campesterol, sitosterol and cholesterol in healthy subjects suggests that efflux transporters controlling intestinal sterol absorption also regulate biliary secretion.
    • Sudhop, T, Sahin, Y, Lindenthal, B, Hahn, C, Lürs, C, Berthold, H.K., et al. Comparison of the hepatic clearances of campesterol, sitosterol and cholesterol in healthy subjects suggests that efflux transporters controlling intestinal sterol absorption also regulate biliary secretion. Gut 2002;51: 860-3.
    • (2002) Gut , vol.51
    • Sudhop, T.1    Sahin, Y.2    Lindenthal, B.3    Hahn, C.4    Lürs, C.5    Berthold, H.K.6
  • 34
    • 0025828024 scopus 로고
    • Cholesterol intake and serum cholesterol level.
    • Gotto, A.M. Cholesterol intake and serum cholesterol level. N Engl J Med 1991;324:912-3.
    • (1991) N Engl J Med , vol.324
    • Gotto, A.M.1
  • 35
    • 0025740575 scopus 로고
    • Relationships of serum plant sterols (phytosterols) and cholesterol in 595 hypercholesterolemic subjects, and familial aggregation of phytosterols, cholesterol and premature coronary heart disease in hyperphytosterolemic probands and their first degree relatives.
    • Glueck, C.J., Speirs, J, Tracy, T, Streicher, P, Illig, E, Vandegrift, J. Relationships of serum plant sterols (phytosterols) and cholesterol in 595 hypercholesterolemic subjects, and familial aggregation of phytosterols, cholesterol and premature coronary heart disease in hyperphytosterolemic probands and their first degree relatives. Metabolism 1991;40:842-8.
    • (1991) Metabolism , vol.40
    • Glueck, C.J.1    Speirs, J.2    Tracy, T.3    Streicher, P.4    Illig, E.5    Vandegrift, J.6
  • 37
    • 0034116622 scopus 로고    scopus 로고
    • Independent association of serum squalene and noncholesterol sterols with coronary artery disease in postmenopausal women.
    • Rajaratnam, R.A., Gylling, H, Miettinen, T.A., Independent association of serum squalene and noncholesterol sterols with coronary artery disease in postmenopausal women. J Am Coll Cardiol 2000;35:1185-91.
    • (2000) J Am Coll Cardiol , vol.35
    • Rajaratnam, R.A.1    Gylling, H.2    Miettinen, T.A.3
  • 38
    • 0036916821 scopus 로고    scopus 로고
    • Serum plant sterols as a potential risk factor for coronary heart disease.
    • Sudhop, T, Gottwald, B.M., von Bergmann, K. Serum plant sterols as a potential risk factor for coronary heart disease. Metabolism 2002;51:1519-21.
    • (2002) Metabolism , vol.51
    • Sudhop, T.1    Gottwald, B.M.2    von Bergmann, K.3
  • 40
    • 33645519199 scopus 로고    scopus 로고
    • Plasma sitosterol elevations are associated with an increased incidence of coronary events in men: Results of a nested case-control analysis of the Prospective Cardiovascular Munster (PROCAM) study.
    • Assmann, G, Cullen, P, Erbey, J, Ramey, D.R., Kannenberg, F, Schulte, H. Plasma sitosterol elevations are associated with an increased incidence of coronary events in men: Results of a nested case-control analysis of the Prospective Cardiovascular Munster (PROCAM) study. Nutr Metab Cardiovasc Dis 2006;16:13–21.
    • (2006) Nutr Metab Cardiovasc Dis , vol.16 , pp. 13-21
    • Assmann, G.1    Cullen, P.2    Erbey, J.3    Ramey, D.R.4    Kannenberg, F.5    Schulte, H.6
  • 41
    • 38049054824 scopus 로고    scopus 로고
    • Moderately elevated plant sterol levels are associated with reduced cardiovascular risk-The LASA study.
    • Fassbender, K, Lutjohann, D, Dik, M.G., Bremmer, M, Koenig, J, Walter, S, et al. Moderately elevated plant sterol levels are associated with reduced cardiovascular risk-The LASA study. Atherosclerosis 2006;196;283-8.
    • (2006) Atherosclerosis , vol.196
    • Fassbender, K.1    Lutjohann, D.2    Dik, M.G.3    Bremmer, M.4    Koenig, J.5    Walter, S.6
  • 42
    • 33845973698 scopus 로고    scopus 로고
    • Plasma levels of plant sterols and the risk of future coronary artery disease in apparently healthy men and women; The Prospective Epic-Norfolk Population Study.
    • Pinedo, S, Vissers, M.N., von Bergmann, K, Elharchaoui, M.D., Lutjohann, D, Luben, R, et al. Plasma levels of plant sterols and the risk of future coronary artery disease in apparently healthy men and women; The Prospective Epic-Norfolk Population Study. J Lipid Res 2007;48:139-44.
    • (2007) J Lipid Res , vol.48
    • Pinedo, S.1    Vissers, M.N.2    von Bergmann, K.3    Elharchaoui, M.D.4    Lutjohann, D.5    Luben, R.6
  • 43
    • 0018062606 scopus 로고
    • The composition of a simulated American diet.
    • Ahrens, E.H. Jr, Boucher, C.A. The composition of a simulated American diet. J Am Diet Assoc 1978;73:613-20.
    • (1978) J Am Diet Assoc , vol.73
    • Ahrens, E.H.1    Boucher, C.A.2
  • 44
    • 0017986411 scopus 로고
    • Sterol content of foods of plant origin.
    • Weihrauch, J.L., Gardner, J.M. Sterol content of foods of plant origin. J Am Diet Assoc 1978;73:39–47.
    • (1978) J Am Diet Assoc , vol.73 , pp. 39-47
    • Weihrauch, J.L.1    Gardner, J.M.2
  • 45
    • 0029742730 scopus 로고    scopus 로고
    • Saturated sterols (stanols) in unhydrogenated and hydrogenated edible vegetable oils and in cereal lipids.
    • Dutta, P.C., Appleqvist, L.A. Saturated sterols (stanols) in unhydrogenated and hydrogenated edible vegetable oils and in cereal lipids. J Sci Food Agric 1996;71:383-91.
    • (1996) J Sci Food Agric , vol.71
    • Dutta, P.C.1    Appleqvist, L.A.2
  • 47
    • 0038614979 scopus 로고    scopus 로고
    • Stimulation of cholesterol excretion by the liver X receptor requires ATP-binding cassette transporters G5 and G8.
    • Yu, L, York, J, von Bergmann, K, Lutjohann, D, Cohen, J.C., Hobbs, H.H. Stimulation of cholesterol excretion by the liver X receptor requires ATP-binding cassette transporters G5 and G8. J Biol Chem 2003;278:15565-70.
    • (2003) J Biol Chem , vol.278
    • Yu, L.1    York, J.2    von Bergmann, K.3    Lutjohann, D.4    Cohen, J.C.5    Hobbs, H.H.6
  • 48
    • 33845496061 scopus 로고    scopus 로고
    • Interaction between cholesterol and glucose metabolism during dietary carbohydrate modification in subjects with the metabolic syndrome
    • Hallikainen, M, Toppinen, L, Mykknen, H, Agren, JJ, Laaksonen, DE, Miettinen, TA, et al. Interaction between cholesterol and glucose metabolism during dietary carbohydrate modification in subjects with the metabolic syndrome. Am J Clin Nutr 2006;84:1385-92.
    • (2006) Am J Clin Nutr , vol.84
    • Hallikainen, M.1    Toppinen, L.2    Mykknen, H.3    Agren, J.J.4    Laaksonen, D.E.5    Miettinen, T.A.6
  • 49
    • 0034186204 scopus 로고    scopus 로고
    • Effects of simvastatin and atorvastatin administration on insulin resistance and respiratory quotient in aged dyslipidemic non-insulin dependent diabetic patients.
    • Paolisso, G, Barbagallo, M, Petrella, G, Ragno, E, Barbieri, M, Giordano, M, et al. Effects of simvastatin and atorvastatin administration on insulin resistance and respiratory quotient in aged dyslipidemic non-insulin dependent diabetic patients. Atherosclerosis 2000;150:121-7.
    • (2000) Atherosclerosis , vol.150
    • Paolisso, G.1    Barbagallo, M.2    Petrella, G.3    Ragno, E.4    Barbieri, M.5    Giordano, M.6
  • 50
    • 0036326046 scopus 로고    scopus 로고
    • Cerivastatin improves insulin sensitivity and insulin secretion in early state obese type 2 diabetes.
    • Paniagua, J.A., Lopez-Miranda, J, Escribano, A, Berral, F.J., Marin, C, Bravo, D, et al. Cerivastatin improves insulin sensitivity and insulin secretion in early state obese type 2 diabetes. Diabetes 2002;51:2596-603.
    • (2002) Diabetes , vol.51
    • Paniagua, J.A.1    Lopez-Miranda, J.2    Escribano, A.3    Berral, F.J.4    Marin, C.5    Bravo, D.6
  • 51
    • 0035897696 scopus 로고    scopus 로고
    • National Cholesterol Education Program.
    • Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • National Cholesterol Education Program. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). J Am Med Assoc 2001; 285:2486-97.
    • (2001) J Am Med Assoc , vol.285
  • 53
    • 0033919190 scopus 로고    scopus 로고
    • Introducing a new component of the metabolic syndrome: low cholesterol absorption.
    • Simonen, P, Gylling, H, Howard, A.N., Miettinen, T.A. Introducing a new component of the metabolic syndrome: low cholesterol absorption. Am J Clin Nutr 2000;72:82-8.
    • (2000) Am J Clin Nutr , vol.72
    • Simonen, P.1    Gylling, H.2    Howard, A.N.3    Miettinen, T.A.4
  • 54
    • 0033790554 scopus 로고    scopus 로고
    • Cholesterol absorption efficiency and sterol metabolism in obesity.
    • Miettinen, T.A., Gyling, H. Cholesterol absorption efficiency and sterol metabolism in obesity. Atherosclerosis 2000; 153:241-8.
    • (2000) Atherosclerosis , vol.153
    • Miettinen, T.A.1    Gyling, H.2
  • 56
    • 0036581197 scopus 로고    scopus 로고
    • Body weight modulates cholesterol metabolism in non-insulin dependent type 2 diabetics.
    • Simonen, P, Gylling, H, Miettinen, T.A. Body weight modulates cholesterol metabolism in non-insulin dependent type 2 diabetics. Obes Res 2002;10:328-35.
    • (2002) Obes Res , vol.10
    • Simonen, P.1    Gylling, H.2    Miettinen, T.A.3
  • 57
    • 0029884567 scopus 로고    scopus 로고
    • Associations of fasting glucose with cholesterol absorption and synthesis in nondiabetic middle-aged men.
    • Strandberg, T.E., Salomaa, V., Vanhanen, H, Miettinen, T.A., Associations of fasting glucose with cholesterol absorption and synthesis in nondiabetic middle-aged men. Diabetes 1996; 45:755-61.
    • (1996) Diabetes , vol.45
    • Strandberg, T.E.1    Salomaa, V.2    Vanhanen, H.3    Miettinen, T.A.4
  • 58
    • 1542723726 scopus 로고    scopus 로고
    • Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men.
    • Pihlajamäki, J, Gylling, H, Miettinen, T.A., Laakso, M. Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men. J Lipid Res 2004;45:507-12.
    • (2004) J Lipid Res , vol.45
    • Pihlajamäki, J.1    Gylling, H.2    Miettinen, T.A.3    Laakso, M.4
  • 59
    • 0036726421 scopus 로고    scopus 로고
    • Diabetes contributes to cholesterol metabolism regardless of obesity.
    • Simonen, P.P., Gylling, H.K., Miettinen, T.A. Diabetes contributes to cholesterol metabolism regardless of obesity. Diabetes Care 2002;25:1511-5.
    • (2002) Diabetes Care , vol.25
    • Simonen, P.P.1    Gylling, H.K.2    Miettinen, T.A.3
  • 60
    • 0031016436 scopus 로고    scopus 로고
    • Cholesterol absorption, synthesis, and LDL metabolism in NIDDM.
    • Gylling, H, Miettinen, T.A. Cholesterol absorption, synthesis, and LDL metabolism in NIDDM. Diabetes Care 1997;20: 90-5.
    • (1997) Diabetes Care , vol.20
    • Gylling, H.1    Miettinen, T.A.2
  • 64
    • 0942279560 scopus 로고    scopus 로고
    • Down-regulation of hepatic and intestinal AGC G5 and ABC G8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes.
    • Bloks, V.W., Bakker-van Waarde, W.M., Verkade, H.J., Kema, I.P., Wolters, H, Vink, E, et al. Down-regulation of hepatic and intestinal AGC G5 and ABC G8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes. Diabetologia 2004;47:104-12.
    • (2004) Diabetologia , vol.47
    • Bloks, V.W.1    Bakker-van Waarde, W.M.2    Verkade, H.J.3    Kema, I.P.4    Wolters, H.5    Vink, E.6
  • 65
    • 0242721947 scopus 로고    scopus 로고
    • Synthesis and absorption markers of cholesterol in serum and lipoproteins during a large dose statin treatment.
    • Miettinen, T.A., Gylling, H. Synthesis and absorption markers of cholesterol in serum and lipoproteins during a large dose statin treatment. Eur J Clin Invest 2003;33:976-82.
    • (2003) Eur J Clin Invest , vol.33
    • Miettinen, T.A.1    Gylling, H.2
  • 66
    • 0034019728 scopus 로고    scopus 로고
    • Noncholesterol sterols and cholesterol lowering by long-term simvastatin treatment in coronary patients: relation to basal serum cholestanol.
    • Miettinen, T.A., Strandberg, T.E., Gylling, H. Noncholesterol sterols and cholesterol lowering by long-term simvastatin treatment in coronary patients: relation to basal serum cholestanol. Arterioscler Thromb Vasc Biol 2000;20:1340-6.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20
    • Miettinen, T.A.1    Strandberg, T.E.2    Gylling, H.3
  • 67
    • 0032507494 scopus 로고    scopus 로고
    • Baseline serum cholestanol as predictor of recurrent coronary events in subgroup of Scandinavian simvastatin survival study.
    • Miettinen, T.A., Gylling, H, Strandberg, T, Sarna, S. Baseline serum cholestanol as predictor of recurrent coronary events in subgroup of Scandinavian simvastatin survival study. Br Med J 1998;316:1127-30.
    • (1998) Br Med J , vol.316
    • Miettinen, T.A.1    Gylling, H.2    Strandberg, T.3    Sarna, S.4
  • 68
    • 34247154875 scopus 로고    scopus 로고
    • Regarding the potential perils of phytosterols.
    • Brendsel, J, Green, S.J. Regarding the potential perils of phytosterols. Atherosclerosis 2007;192:227-9.
    • (2007) Atherosclerosis , vol.192
    • Brendsel, J.1    Green, S.J.2
  • 69
    • 0035957037 scopus 로고    scopus 로고
    • Stanol/sterol-ester-containing foods and blood cholesterol levels: A statement for healthcare professionals from the nutrition committee of the council on nutrition, physical activity, and metabolism of the American Heart Association.
    • Lichtenstein, A.H., Deckelbaum, R.J., Stanol/sterol-ester-containing foods and blood cholesterol levels: A statement for healthcare professionals from the nutrition committee of the council on nutrition, physical activity, and metabolism of the American Heart Association. Circulation 2001;103:1177-9.
    • (2001) Circulation , vol.103
    • Lichtenstein, A.H.1    Deckelbaum, R.J.2
  • 70
    • 0034107086 scopus 로고    scopus 로고
    • Soy sterol esters and beta-sitostanol ester as inhibitors of cholesterol absorption in human small bowel.
    • Normen, L, Dutta, P, Lia, A, Anderssson, H. Soy sterol esters and beta-sitostanol ester as inhibitors of cholesterol absorption in human small bowel. Am J Clin Nutr 2000;71:908-13.
    • (2000) Am J Clin Nutr , vol.71
    • Normen, L.1    Dutta, P.2    Lia, A.3    Anderssson, H.4
  • 71
    • 21244487468 scopus 로고    scopus 로고
    • Plant stanol and sterol esters in the control of blood cholesterol levels: Mechanism and safety aspects.
    • Plat, J, Mensink, R.P. Plant stanol and sterol esters in the control of blood cholesterol levels: Mechanism and safety aspects. Am J Cardiol 2005;96:15D-22.
    • (2005) Am J Cardiol , vol.96
    • Plat, J.1    Mensink, R.P.2
  • 72
    • 0042206849 scopus 로고    scopus 로고
    • Efficacy of plant sterols and stanols in the management of blood cholesterol levels.
    • for the Stresa Workshop Participants.
    • Katan, M.B., Grundy, S.M., Jones, P, Law, M, Miettinen, T.A., Paoletti, R, for the Stresa Workshop Participants. Efficacy of plant sterols and stanols in the management of blood cholesterol levels. Mayo Clin Proc 2003;78:965-78.
    • (2003) Mayo Clin Proc , vol.78
    • Katan, M.B.1    Grundy, S.M.2    Jones, P.3    Law, M.4    Miettinen, T.A.5    Paoletti, R.6
  • 74
    • 0033528702 scopus 로고    scopus 로고
    • Proatherogenic and antiatherogenic effects of probucol and phytosterols in apolipoprotein E-deficient mice: Possible mechanisms of action.
    • Moghadasian, M.H., Mc Manus, B.M., Godin, D.V., Rodrigues, B, Frolich, J.J. Proatherogenic and antiatherogenic effects of probucol and phytosterols in apolipoprotein E-deficient mice: Possible mechanisms of action. Circulation 1999;99: 1733-9.
    • (1999) Circulation , vol.99
    • Moghadasian, M.H.1    Mc Manus, B.M.2    Godin, D.V.3    Rodrigues, B.4    Frolich, J.J.5
  • 75
    • 33845563662 scopus 로고    scopus 로고
    • Plant sterol or stanol esters retard lesion formation in LDL receptor-deficient mice independent of changes in serum plant sterols.
    • Plat, J, Beugels, I, Gijbels, M.J., de Winter, M.P., Mensink, R.P. Plant sterol or stanol esters retard lesion formation in LDL receptor-deficient mice independent of changes in serum plant sterols. J Lipid Res 2006;47:2762-71.
    • (2006) J Lipid Res , vol.47
    • Plat, J.1    Beugels, I.2    Gijbels, M.J.3    de Winter, M.P.4    Mensink, R.P.5
  • 76
    • 41949115935 scopus 로고    scopus 로고
    • Effects of longterm plant sterol or stanol ester consumption on endothelial function and arterial stiffness in patients on statin treatment (Abstr).
    • de Jong, A, Plat, J, Hoeks, A.P., Mensink, R.P. Effects of longterm plant sterol or stanol ester consumption on endothelial function and arterial stiffness in patients on statin treatment (Abstr). Atherosclerosis 2007;8:1.
    • (2007) Atherosclerosis , vol.8 , pp. 1
    • de Jong, A.1    Plat, J.2    Hoeks, A.P.3    Mensink, R.P.4
  • 77
    • 41949092417 scopus 로고    scopus 로고
    • Plant stanol ester consumption and arterial elasticity and endothelial function.
    • Feb 18; [E-pub ahead of print].
    • Raitakari, O.T., Salo, P, Gylling, H, Miettinen, T.A. Plant stanol ester consumption and arterial elasticity and endothelial function. Br J Nutr 2008 Feb 18; [E-pub ahead of print].
    • (2008) Br J Nutr
    • Raitakari, O.T.1    Salo, P.2    Gylling, H.3    Miettinen, T.A.4
  • 78
    • 34247859014 scopus 로고    scopus 로고
    • Customary use of plant sterol and plant stanol enriched margarine is associated with changes in serum plant sterol and stanol concentrations in humans.
    • Fransen, H.P., de Jong, N, Wolfs, M, Verhagen, H, Verschurenm, W.M., Lütjohann, D, et al. Customary use of plant sterol and plant stanol enriched margarine is associated with changes in serum plant sterol and stanol concentrations in humans. J Nutr 2007;137:1301-6.
    • (2007) J Nutr , vol.137
    • Fransen, H.P.1    de Jong, N.2    Wolfs, M.3    Verhagen, H.4    Verschurenm, W.M.5    Lütjohann, D.6
  • 79
    • 0031745196 scopus 로고    scopus 로고
    • Plant sterol-enriched margarines and reduction of plasma total- and LDL-cholesterol concentrations in normocholesterolaemic and mildly hyperchole-sterolaemic subjects.
    • Weststrate, J.A., Meijer, G.W. Plant sterol-enriched margarines and reduction of plasma total- and LDL-cholesterol concentrations in normocholesterolaemic and mildly hyperchole-sterolaemic subjects. Eur J Clin Nutr 1998;52:334-43.
    • (1998) Eur J Clin Nutr , vol.52
    • Weststrate, J.A.1    Meijer, G.W.2
  • 80
    • 0016366624 scopus 로고
    • β-Sitosterolaemia and xanthomatosis. A newly described lipid storage disease in two sisters.
    • Bhattacharyya, A, Connor, W.E. β-Sitosterolaemia and xanthomatosis. A newly described lipid storage disease in two sisters. J Clin Invest 1974;53:1033-43.
    • (1974) J Clin Invest , vol.53
    • Bhattacharyya, A.1    Connor, W.E.2
  • 81
    • 0022634330 scopus 로고
    • Genetic analysis of plasma sitosterol, apolipoprotein B, and lipoproteins in a large Amish pedigree with sitosterolaemia.
    • Beaty, T.H., Kwiterowich, P.O. Jr., Khoury, M.J., White, S, Bachorik, P.S., Smith, H.H., et al. Genetic analysis of plasma sitosterol, apolipoprotein B, and lipoproteins in a large Amish pedigree with sitosterolaemia. Am J Hum Genet 1986;38: 492–504.
    • (1986) Am J Hum Genet , vol.38 , pp. 492-504
    • Beaty, T.H.1    Kwiterowich, P.O.2    Khoury, M.J.3    White, S.4    Bachorik, P.S.5    Smith, H.H.6
  • 82
    • 0025912236 scopus 로고
    • Sluggish sitosterol turnover and hepatic failure to excrete sitosterol into bile cause expansion of body pool sitosterol in patients with sitosterolaemia and xanthomatosis.
    • Bhattacharrya, A.K., Connor, W.E., Lin, D.S., McMurry, M.M., Shulman, R.S. Sluggish sitosterol turnover and hepatic failure to excrete sitosterol into bile cause expansion of body pool sitosterol in patients with sitosterolaemia and xanthomatosis. Atheroscler Thromb 1991;11:1287-94.
    • (1991) Atheroscler Thromb , vol.11
    • Bhattacharrya, A.K.1    Connor, W.E.2    Lin, D.S.3    McMurry, M.M.4    Shulman, R.S.5
  • 83
    • 0025132445 scopus 로고
    • Molecular defect in cholesterol synthesis in sitosterolaemia with xanthomatosis.
    • Nguyen, L, Shefer, S, Salen, G, Ness, GC, Tint, GS, Zaki, FG, et al. Molecular defect in cholesterol synthesis in sitosterolaemia with xanthomatosis. J Clin Invest 1990;86:926-31.
    • (1990) J Clin Invest , vol.86
    • Nguyen, L.1    Shefer, S.2    Salen, G.3    Ness, G.C.4    Tint, G.S.5    Zaki, F.G.6
  • 84
    • 0028200779 scopus 로고
    • The effect of increased hepatic sitosterol on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the rat and sitosterolaemic homozygotes.
    • Shefer, S, Salen, G, Bullock, J, Nguyen, L.B., Ness, G.C., Vhao, Z, et al. The effect of increased hepatic sitosterol on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the rat and sitosterolaemic homozygotes. Hepatology 1994;20: 213-9.
    • (1994) Hepatology , vol.20
    • Shefer, S.1    Salen, G.2    Bullock, J.3    Nguyen, L.B.4    Ness, G.C.5    Vhao, Z.6
  • 85
    • 0031985824 scopus 로고    scopus 로고
    • Competitive inhibition of hepatic 27-hydroxylase by sitosterol: decreased activity in sitosterolaemia.
    • Nguyen, L.B., Shefer, S, Salen, G, Tint, S.G., Batta, A.K. Competitive inhibition of hepatic 27-hydroxylase by sitosterol: decreased activity in sitosterolaemia. Proc Assoc Am Phys 1998;110:32-9.
    • (1998) Proc Assoc Am Phys , vol.110
    • Nguyen, L.B.1    Shefer, S.2    Salen, G.3    Tint, S.G.4    Batta, A.K.5
  • 91
    • 0018841909 scopus 로고
    • Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption impaired sterol elimination and low cholesterol synthesis.
    • Miettinen, T.A. Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption impaired sterol elimination and low cholesterol synthesis. Eur J Clin Invest 1980;10:27–35.
    • (1980) Eur J Clin Invest , vol.10 , pp. 27-35
    • Miettinen, T.A.1
  • 93
    • 0022197146 scopus 로고
    • Lethal atherosclerosis associated with abnormal plasma and tissue sterol composition in sitosterolaemia with xanthomatosis.
    • Salen, G, Horak, I, Rothkopf, M, Cohen, J.L., Speck, J, Tint, G.S., et al. Lethal atherosclerosis associated with abnormal plasma and tissue sterol composition in sitosterolaemia with xanthomatosis. J Lipid Res 1985;26:1126-33.
    • (1985) J Lipid Res , vol.26
    • Salen, G.1    Horak, I.2    Rothkopf, M.3    Cohen, J.L.4    Speck, J.5    Tint, G.S.6
  • 95
    • 0038506462 scopus 로고    scopus 로고
    • Images in clinical medicine: Phytosterole-mia and xanthomatosis.
    • Stalenhoef, A.F. Images in clinical medicine: Phytosterole-mia and xanthomatosis. N Engl J Med 2003;349:51.
    • (2003) N Engl J Med , vol.349 , pp. 51
    • Stalenhoef, A.F.1
  • 97
    • 24944465805 scopus 로고    scopus 로고
    • Stomato-cytic haemolysis and macrothrombocytopenia(Mediter-ranean stomatocytosis/macrothrombocytopenia) is the haematological presentation of phytosterolaemia.
    • Rees, D.C., Iolascon, A, Carella, M, Stewart, G.W. Stomato-cytic haemolysis and macrothrombocytopenia(Mediter-ranean stomatocytosis/macrothrombocytopenia) is the haematological presentation of phytosterolaemia. Br J Haemat 2005;130:297–309.
    • (2005) Br J Haemat , vol.130 , pp. 297-309
    • Rees, D.C.1    Iolascon, A.2    Carella, M.3    Stewart, G.W.4
  • 99
    • 0026349380 scopus 로고
    • Regulation of cholesterol biosynthesis in sitosterolaemia: effects of lovastatin, cholestyramin, and dietary sterol restriction.
    • Nguyen, L.B., Cobb, M, Shefer, S, Salen, G, Ness, GC, Tint, GS, Regulation of cholesterol biosynthesis in sitosterolaemia: effects of lovastatin, cholestyramin, and dietary sterol restriction. J Lipid Res 1991;32:1941-8.
    • (1991) J Lipid Res , vol.32
    • Nguyen, L.B.1    Cobb, M.2    Shefer, S.3    Salen, G.4    Ness, G.C.5    Tint, G.S.6
  • 100
    • 0028877287 scopus 로고
    • A marked and sustained reduction in LDL sterols by diet and cholestyramine in β-sitosterolaemia.
    • Parsons, H.G., Jamal, R, Baylis, B. A marked and sustained reduction in LDL sterols by diet and cholestyramine in β-sitosterolaemia. Clin Invest Med 1995;18:389–400.
    • (1995) Clin Invest Med , vol.18 , pp. 389-400
    • Parsons, H.G.1    Jamal, R.2    Baylis, B.3
  • 103
    • 20344371460 scopus 로고    scopus 로고
    • Plant sterols in serum and in atherosclerotic plaques of patients undergoing carotid endartectomy.
    • Miettinen, T.A., Railo, M, Lepäntalo, M, Gylling, H. Plant sterols in serum and in atherosclerotic plaques of patients undergoing carotid endartectomy. J Am Coll Cardiol 2005;45: 1794-801.
    • (2005) J Am Coll Cardiol , vol.45
    • Miettinen, T.A.1    Railo, M.2    Lepäntalo, M.3    Gylling, H.4
  • 106
    • 33746817894 scopus 로고    scopus 로고
    • Cholesterol and glucose metabolism and recurrent cardiovascular events among elderly.
    • Strandberg, T.E., Tilvis, R.S., Pitkala, K.H., Miettinen, T.A. Cholesterol and glucose metabolism and recurrent cardiovascular events among elderly. J Am Coll Cardiol 2006;48: 708-14.
    • (2006) J Am Coll Cardiol , vol.48
    • Strandberg, T.E.1    Tilvis, R.S.2    Pitkala, K.H.3    Miettinen, T.A.4


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