Competitive inhibition of hepatic sterol 27-hydroxylase by sitosterol: Decreased activity in sitosterolemia

Proceedings of the Association of American Physicians

Volumn 110, Issue 1, 1998, Pages 32-39

  Nguyen, L B ^a   Shefer, S ^a   Salen, G ^a   Tint, S G ^a   Batta, A K ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Atherosclerosis; Bile acids; Cholesterol 7 hydroxylase; Cholesterol catabolism; Hypercholesterolemia; Plant sterols

Indexed keywords

ANDROSTANOLONE DERIVATIVE; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; LIVER ENZYME; MITOCHONDRIAL ENZYME; OXYGENASE; PHYTOSTEROL; SITOSTEROL; STEROL 27 HYDROXYLASE; STEROL DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; BILE ACID SYNTHESIS; CHOLESTEROL METABOLISM; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME INACTIVATION; FAMILIAL HYPERCHOLESTEROLEMIA; FEMALE; HUMAN; HUMAN TISSUE; LIVER MITOCHONDRION; MALE; NONHUMAN; RAT; RISK FACTOR; SITOSTEROLEMIA; STEROL SYNTHESIS;

ANIMALS; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CYTOCHROME P-450 CYP27A1; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HUMANS; LIPID METABOLISM, INBORN ERRORS; LIVER; MALE; RATS; RATS, SPRAGUE-DAWLEY; SITOSTEROLS; STEROID HYDROXYLASES;

EID: 0031985824     PISSN: 1081650X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)