Melatonin attenuated early brain injury induced by subarachnoid hemorrhage via regulating NLRP3 inflammasome and apoptosis signaling

Journal of Pineal Research

Volumn 60, Issue 3, 2016, Pages 253-262

  Dong, Yushu ^a   Fan, Chongxi ^b,c   Hu, Wei ^b   Jiang, Shuai ^b   Ma, Zhiqiang ^c   Yan, Xiaolong ^c   Deng, Chao ^d   Di, Shouyin ^c   Xin, Zhenlong ^b   Wu, Guiling ^b   Yang, Yang ^b   Reiter, Russel J ^e   Liang, Guobiao ^a  

^a GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^e UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

early brain injury; inflammasome; melatonin; nucleotide binding oligomerization domain like receptor family pyrin domain containing 3; subarachnoid hemorrhage

Indexed keywords

BIM PROTEIN; CRYOPYRIN; GLUTATHIONE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; MALONALDEHYDE; MELATONIN; NEUROPROTECTIVE AGENT; PROTEIN BCL 2; IL1B PROTEIN, MOUSE; NLRP3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN INJURY; BRAIN LEVEL; BRAIN WATER; CONTROLLED STUDY; MOUSE; NEUROPROTECTION; NONHUMAN; SUBARACHNOID HEMORRHAGE; SURVIVAL RATE; UPREGULATION; WATER CONTENT; ANIMAL; BIOSYNTHESIS; BRAIN HEMORRHAGE; DRUG EFFECTS; GENE EXPRESSION REGULATION; MALE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BLOOD-BRAIN BARRIER; BRAIN HEMORRHAGE, TRAUMATIC; CASPASE 1; GENE EXPRESSION REGULATION; INFLAMMASOMES; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; MELATONIN; MICE; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; SIGNAL TRANSDUCTION; SUBARACHNOID HEMORRHAGE;

EID: 84975742355     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12300     Document Type: Article

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