메뉴 건너뛰기




Volumn 54, Issue 4, 2013, Pages 381-388

Melatonin ameliorates low-grade inflammation and oxidative stress in young Zucker diabetic fatty rats

Author keywords

Low grade inflammation; Melatonin; Oxidative stress; Zucker diabetic fatty rats

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 6; MALONALDEHYDE; MELATONIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84879459393     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12012     Document Type: Article
Times cited : (121)

References (66)
  • 1
    • 37349066531 scopus 로고    scopus 로고
    • International Day for the Evaluation of Abdominal Obesity (IDEA): A study of waist circumference, cardiovascular disease, and diabetes mellitus in 168,000 primary care patients in 63 countries
    • BALKAU B, DEANFIELD JE, DESPRES JP et al. International Day for the Evaluation of Abdominal Obesity (IDEA): a study of waist circumference, cardiovascular disease, and diabetes mellitus in 168,000 primary care patients in 63 countries. Circulation 2007; 116:1942-1951.
    • (2007) Circulation , vol.116 , pp. 1942-1951
    • Balkau, B.1    Deanfield, J.E.2    Despres, J.P.3
  • 3
    • 34547684523 scopus 로고    scopus 로고
    • Childhood overweight, obesity, and the metabolic syndrome in developing countries
    • KELISHADI R. Childhood overweight, obesity, and the metabolic syndrome in developing countries. Epidemiol Rev 2007; 29:62-76.
    • (2007) Epidemiol Rev , vol.29 , pp. 62-76
    • Kelishadi, R.1
  • 4
    • 26244463170 scopus 로고    scopus 로고
    • Role of impaired insulin secretion and insulin resistance in the pathogenesis of type 2 diabetes mellitus
    • SZOKE E, GERICH JE. Role of impaired insulin secretion and insulin resistance in the pathogenesis of type 2 diabetes mellitus. Compr Ther 2005; 31:106-112.
    • (2005) Compr Ther , vol.31 , pp. 106-112
    • Szoke, E.1    Gerich, J.E.2
  • 5
    • 77957078371 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and inflammation in obesity and diabetes
    • HUMMASTI S, HOTAMISLIGIL GS. Endoplasmic reticulum stress and inflammation in obesity and diabetes. Circ Res 2010; 107:579-591.
    • (2010) Circ Res , vol.107 , pp. 579-591
    • Hummasti, S.1    Hotamisligil, G.S.2
  • 6
    • 58249110569 scopus 로고    scopus 로고
    • Positive and negative regulation of insulin signaling by reactive oxygen and nitrogen species
    • BASHAN N, KOVSAN J, KACHKO I et al. Positive and negative regulation of insulin signaling by reactive oxygen and nitrogen species. Physiol Rev 2009; 89:27-71.
    • (2009) Physiol Rev , vol.89 , pp. 27-71
    • Bashan, N.1    Kovsan, J.2    Kachko, I.3
  • 7
    • 78650655664 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention
    • BADAWI A, KLIP A, HADDAH P et al. Type 2 diabetes mellitus and inflammation: prospects for biomarkers of risk and nutritional intervention. Diabetes Metab Syndr Obes 2010; 3:173-186.
    • (2010) Diabetes Metab Syndr Obes , vol.3 , pp. 173-186
    • Badawi, A.1    Klip, A.2    Haddah, P.3
  • 9
    • 55849114349 scopus 로고    scopus 로고
    • Adipocytokines and the metabolic complications of obesity
    • RASOULIN, KERN PA. Adipocytokines and the metabolic complications of obesity. J Clin Endocrinol Metab 2008; 93: S64-S73.
    • (2008) J Clin Endocrinol Metab , vol.93
    • Rasoulin1    Kern, P.A.2
  • 10
    • 73949146152 scopus 로고    scopus 로고
    • Current views on type 2 diabetes
    • LIN Y, SUN Z. Current views on type 2 diabetes. J Endocrinol 2010; 204:1-11.
    • (2010) J Endocrinol , vol.204 , pp. 1-11
    • Lin, Y.1    Sun, Z.2
  • 11
    • 73949126369 scopus 로고    scopus 로고
    • Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes
    • DONATH MY, BONI-SCHNETZLER M, ELLINGSGAARD H et al. Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes. Physiology (Bethesda) 2009; 24:325-331.
    • (2009) Physiology (Bethesda) , vol.24 , pp. 325-331
    • Donath, M.Y.1    Boni-Schnetzler, M.2    Ellingsgaard, H.3
  • 12
    • 70449494871 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in beta-cells and development of diabetes
    • FONSECA SG, BURCIN M, GROMADA J et al. Endoplasmic reticulum stress in beta-cells and development of diabetes. Curr Opin Pharmacol 2009; 9:763-770.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 763-770
    • Fonseca, S.G.1    Burcin, M.2    Gromada, J.3
  • 13
    • 70349398318 scopus 로고    scopus 로고
    • Beta-cell deterioration during diabetes: What's in the gun?
    • ROBERTSON RP. Beta-cell deterioration during diabetes: what's in the gun? Trends Endocrinol Metab 2009; 20:388-393.
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 388-393
    • Robertson, R.P.1
  • 14
    • 0025758136 scopus 로고
    • Pineal melatonin: Cell biology of its synthesis and of its physiological interactions
    • REITER RJ. Pineal melatonin: cell biology of its synthesis and of its physiological interactions. Endocr Rev 1991; 12:151-180.
    • (1991) Endocr Rev , vol.12 , pp. 151-180
    • Reiter, R.J.1
  • 15
    • 0035049581 scopus 로고    scopus 로고
    • Gene expression of the key enzymes of melatonin synthesis in extrapineal tissues of the rat
    • STEFULJ J, HORTNER M, GHOSH M et al. Gene expression of the key enzymes of melatonin synthesis in extrapineal tissues of the rat. J Pineal Res 2001; 30:243-247.
    • (2001) J Pineal Res , vol.30 , pp. 243-247
    • Stefulj, J.1    Hortner, M.2    Ghosh, M.3
  • 16
    • 84856735219 scopus 로고    scopus 로고
    • Melatonin, the circadian multioscillator system and health: The need for detailed analysis of peripheral melatonin signaling
    • HARDELAND R, MADRID JA, TAN DX et al. Melatonin, the circadian multioscillator system and health: the need for detailed analysis of peripheral melatonin signaling. J Pineal Res 2012; 52:139-166.
    • (2012) J Pineal Res , vol.52 , pp. 139-166
    • Hardeland, R.1    Madrid, J.A.2    Tan, D.X.3
  • 17
    • 79951838117 scopus 로고    scopus 로고
    • Significance and application of melatonin in the regulation of brown adipose tissue metabolism: Relation to human obesity
    • TAN DX, MANCHESTER LC, FUENTES-BROTO L et al. Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity. Obes Rev 2011; 12:167-188.
    • (2011) Obes Rev , vol.12 , pp. 167-188
    • Tan, D.X.1    Manchester, L.C.2    Fuentes-Broto, L.3
  • 18
    • 77950663581 scopus 로고    scopus 로고
    • Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease
    • PARADIES G, PETROSILLO G, PARADIES V et al. Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease. J Pineal Res 2010; 48:297-310.
    • (2010) J Pineal Res , vol.48 , pp. 297-310
    • Paradies, G.1    Petrosillo, G.2    Paradies, V.3
  • 19
    • 22144498398 scopus 로고    scopus 로고
    • Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages
    • MAYO JC, SAINZ RM, TAN DX et al. Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages. J Neuroimmunol 2005; 165:139-149.
    • (2005) J Neuroimmunol , vol.165 , pp. 139-149
    • Mayo, J.C.1    Sainz, R.M.2    Tan, D.X.3
  • 20
    • 27644466592 scopus 로고    scopus 로고
    • A review of the multiple actions of melatonin on the immune system
    • CARRILLO-VICO A, GUERRERO JM, LARDONE PJ et al. A review of the multiple actions of melatonin on the immune system. Endocrine 2005; 27:189-200.
    • (2005) Endocrine , vol.27 , pp. 189-200
    • Carrillo-Vico, A.1    Guerrero, J.M.2    Lardone, P.J.3
  • 21
    • 78049451374 scopus 로고    scopus 로고
    • Melatonin: A pleiotropic molecule regulating inflammation
    • RADOGNA F, DIEDERICH M, GHIBELLI L. Melatonin: a pleiotropic molecule regulating inflammation. Biochem Pharmacol 2010; 80:1844-1852.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1844-1852
    • Radogna, F.1    Diederich, M.2    Ghibelli, L.3
  • 22
    • 0002979059 scopus 로고
    • Melatonin: A potent, endogenous hydroxyl radical scavenger
    • TAN DX, CHEN L, POEGGELER B et al. Melatonin: a potent, endogenous hydroxyl radical scavenger. J Pineal Res 1993; 1:57-60.
    • (1993) J Pineal Res , vol.1 , pp. 57-60
    • Tan, D.X.1    Chen, L.2    Poeggeler, B.3
  • 23
    • 68249129060 scopus 로고    scopus 로고
    • Kynuramines, metabolites of melatonin and other indoles: The resurrection of an almost forgotten class of biogenic amines
    • HARDELAND R, TAN DX, REITER RJ. Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. J Pineal Res 2009; 47:109-126.
    • (2009) J Pineal Res , vol.47 , pp. 109-126
    • Hardeland, R.1    Tan, D.X.2    Reiter, R.J.3
  • 24
    • 57149130854 scopus 로고    scopus 로고
    • The melatonin metabolite N-acetyl-5-methoxykynuramine is a potent singlet oxygen scavenger
    • SCHAEFER M, HARDELAND R. The melatonin metabolite N-acetyl-5- methoxykynuramine is a potent singlet oxygen scavenger. J Pineal Res 2009; 46:49-52.
    • (2009) J Pineal Res , vol.46 , pp. 49-52
    • Schaefer, M.1    Hardeland, R.2
  • 25
    • 59649119052 scopus 로고    scopus 로고
    • Melatonin; An established antixoidant worthy of use in clinical trial
    • KORKMAZ A, REITER RJ, TOPAL T et al. Melatonin; an established antixoidant worthy of use in clinical trial. Mol Med 2009; 15:43-50.
    • (2009) Mol Med , vol.15 , pp. 43-50
    • Korkmaz, A.1    Reiter, R.J.2    Topal, T.3
  • 26
    • 70349577367 scopus 로고    scopus 로고
    • Reducing oxidative/nitrosative stress: A newly-discovered genre for melatonin
    • REITER RJ, PAREDES SD, MANCHESTER LC et al. Reducing oxidative/ nitrosative stress: a newly-discovered genre for melatonin. Crit Rev Biochem Mol Biol 2009; 44:175-200.
    • (2009) Crit Rev Biochem Mol Biol , vol.44 , pp. 175-200
    • Reiter, R.J.1    Paredes, S.D.2    Manchester, L.C.3
  • 27
    • 79952573098 scopus 로고    scopus 로고
    • Reaction mechanism of melatonin oxidation by reactive oxygen species in vitro
    • BONNEFONT-ROUSSELOT D, COLLIN F, JORE D et al. Reaction mechanism of melatonin oxidation by reactive oxygen species in vitro. J Pineal Res 2011; 50:328-335.
    • (2011) J Pineal Res , vol.50 , pp. 328-335
    • Bonnefont-Rousselot, D.1    Collin, F.2    Jore, D.3
  • 28
    • 79960380554 scopus 로고    scopus 로고
    • Melatonin as a natural ally against oxidative stress: A physicochemical examination
    • GALANO A, TAN DX, REITER RJ. Melatonin as a natural ally against oxidative stress: a physicochemical examination. J Pineal Res 2011; 51:1-16.
    • (2011) J Pineal Res , vol.51 , pp. 1-16
    • Galano, A.1    Tan, D.X.2    Reiter, R.J.3
  • 29
    • 0032962371 scopus 로고    scopus 로고
    • Daily melatonin administration at middle age suppresses male rat visceral fat, plasma leptin, and plasma insulin to youthful levels
    • RASMUSSEN DD, BOLDT BM, WILKINSON CW et al. Daily melatonin administration at middle age suppresses male rat visceral fat, plasma leptin, and plasma insulin to youthful levels. Endocrinology 1999; 140:1009-1012.
    • (1999) Endocrinology , vol.140 , pp. 1009-1012
    • Rasmussen, D.D.1    Boldt, B.M.2    Wilkinson, C.W.3
  • 30
    • 78349232360 scopus 로고    scopus 로고
    • Melatonin effect on plasma adiponectin, leptin, insulin, glucose, triglycerides and cholesterol in normal and high fat-fed rats
    • RIOS-LUGO MJ, CANO P, JIMENEZ-ORTEGA V et al. Melatonin effect on plasma adiponectin, leptin, insulin, glucose, triglycerides and cholesterol in normal and high fat-fed rats. J Pineal Res 2010; 49:342-348.
    • (2010) J Pineal Res , vol.49 , pp. 342-348
    • Rios-Lugo, M.J.1    Cano, P.2    Jimenez-Ortega, V.3
  • 31
    • 79951667271 scopus 로고    scopus 로고
    • Chronic melatonin consumption prevents obesity-related metabolic abnormalities and protects the heart against myocardial ischemia and reperfusion injury in a prediabetic model of dietinduced obesity
    • NDUHIRABANDI F, DU TOIT EF, BLACKHURST D et al. Chronic melatonin consumption prevents obesity-related metabolic abnormalities and protects the heart against myocardial ischemia and reperfusion injury in a prediabetic model of dietinduced obesity. J Pineal Res 2011; 50:171-182.
    • (2011) J Pineal Res , vol.50 , pp. 171-182
    • Nduhirabandi, F.1    Du Toit, E.F.2    Blackhurst, D.3
  • 32
    • 79951620792 scopus 로고    scopus 로고
    • Beneficial effects of melatonin on obesity and lipid profile in young Zucker diabetic fatty rats
    • AGIL A, NAVARRO-ALARCON M, RUIZ R et al. Beneficial effects of melatonin on obesity and lipid profile in young Zucker diabetic fatty rats. J Pineal Res 2011; 50:207-212.
    • (2011) J Pineal Res , vol.50 , pp. 207-212
    • Agil, A.1    Navarro-Alarcon, M.2    Ruiz, R.3
  • 33
    • 84856689631 scopus 로고    scopus 로고
    • Melatonin improves glucose homeostasis in young Zucker diabetic fatty rats
    • AGIL A, ROSADO I, RUIZ R et al. Melatonin improves glucose homeostasis in young Zucker diabetic fatty rats. J Pineal Res 2011; 52:203-210.
    • (2011) J Pineal Res , vol.52 , pp. 203-210
    • Agil, A.1    Rosado, I.2    Ruiz, R.3
  • 34
    • 79951642115 scopus 로고    scopus 로고
    • Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: Effects on NF-kB and Nrf2 cascades
    • NEGI G, KUMAR A, SHARMA S. Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF-kB and Nrf2 cascades. J Pineal Res 2011; 50:124-131.
    • (2011) J Pineal Res , vol.50 , pp. 124-131
    • Negi, G.1    Kumar, A.2    Sharma, S.3
  • 35
    • 73449142425 scopus 로고    scopus 로고
    • Functional and biochemical evidence indicating beneficial effect of melatonin and nicotinamide alone and in combination in experimental diabetic neuropathy
    • NEGI G, KUMAR A, KAUNDAL RK et al. Functional and biochemical evidence indicating beneficial effect of melatonin and nicotinamide alone and in combination in experimental diabetic neuropathy. Neuropharmacology 2010; 58:585-592.
    • (2010) Neuropharmacology , vol.58 , pp. 585-592
    • Negi, G.1    Kumar, A.2    Kaundal, R.K.3
  • 36
    • 0002803911 scopus 로고
    • Zucker diabetic fatty rat as a model for non-insulin-dependent diabetes mellitus
    • PETERSON R, SHAW W, NEEL M et al. Zucker diabetic fatty rat as a model for non-insulin-dependent diabetes mellitus. Inst Lab Anim Resources News 1990; 32:16-27.
    • (1990) Inst Lab Anim Resources News , vol.32 , pp. 16-27
    • Peterson, R.1    Shaw, W.2    Neel, M.3
  • 37
    • 0026512081 scopus 로고
    • The Zucker rat model of obesity, insulin resistance, hyperlipidemia, and renal injury
    • KASISKE BL, O'DONNELL MP, KEANE WF. The Zucker rat model of obesity, insulin resistance, hyperlipidemia, and renal injury. Hypertension 1992; 19:110-115.
    • (1992) Hypertension , vol.19 , pp. 110-115
    • Kasiske, B.L.1    O'Donnell, M.P.2    Keane, W.F.3
  • 38
    • 0027059040 scopus 로고
    • Animal models of non-insulin-dependent diabetes
    • SHAFRIR E. Animal models of non-insulin-dependent diabetes. Diabetes Metab Rev 1992; 8:179-208.
    • (1992) Diabetes Metab Rev , vol.8 , pp. 179-208
    • Shafrir, E.1
  • 39
    • 73349118496 scopus 로고    scopus 로고
    • Experimental rat models to study the metabolic syndrome
    • ALEIXANDRE DE ARTINANO A, MIGUEL CASTRO M. Experimental rat models to study the metabolic syndrome. Br J Nutr 2009; 102:1246-1253.
    • (2009) Br J Nutr , vol.102 , pp. 1246-1253
    • Aleixandre De Artinano, A.1    Miguel Castro, M.2
  • 40
    • 77955406467 scopus 로고    scopus 로고
    • Effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (ZDF rat)
    • FERREIRA L, TEIXEIRA-DE-LEMOS E, PINTO F et al. Effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (ZDF rat). Mediators Inflamm 2010; 2010: 592760.
    • (2010) Mediators Inflamm , vol.2010 , pp. 592760
    • Ferreira, L.1    Teixeira-De-Lemos, E.2    Pinto, F.3
  • 42
    • 69949093803 scopus 로고    scopus 로고
    • Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications
    • GOLDBERG RB. Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications. J Clin Endocrinol Metab 2009; 94:3171-3182.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3171-3182
    • Goldberg, R.B.1
  • 44
    • 67049099210 scopus 로고    scopus 로고
    • Human C-reactive protein and the metabolic syndrome
    • DEVARAJ S, SINGH U, JIALAL I. Human C-reactive protein and the metabolic syndrome. Curr Opin Lipidol 2009; 20:182-189.
    • (2009) Curr Opin Lipidol , vol.20 , pp. 182-189
    • Devaraj, S.1    Singh, U.2    Jialal, I.3
  • 45
    • 0028944891 scopus 로고
    • Susceptibility of plasma to ferrous iron/hydrogen peroxide-mediated oxidation: Demonstration of a possible fenton reaction
    • AGIL A, FULLER CJ, JIALAL I. Susceptibility of plasma to ferrous iron/hydrogen peroxide-mediated oxidation: Demonstration of a possible fenton reaction. Clin Chem 1995; 41:220-225.
    • (1995) Clin Chem , vol.41 , pp. 220-225
    • Agil, A.1    Fuller, C.J.2    Jialal, I.3
  • 46
    • 0021288840 scopus 로고
    • Assay for blood plasma or serum
    • YAGI K. Assay for blood plasma or serum. Methods Enzymol 1984; 105:328-331.
    • (1984) Methods Enzymol , vol.105 , pp. 328-331
    • Yagi, K.1
  • 48
    • 34047155003 scopus 로고    scopus 로고
    • Visceral fat adipokine secretion is associated with systemic inflammation in obese humans
    • FONTANA L, EAGON JC, TRUJILLO ME et al. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes 2007; 56:1010-1013.
    • (2007) Diabetes , vol.56 , pp. 1010-1013
    • Fontana, L.1    Eagon, J.C.2    Trujillo, M.E.3
  • 49
    • 77953509678 scopus 로고    scopus 로고
    • Adipose tissue, inflammation and atherosclerosis
    • GUSTAFSON B. Adipose tissue, inflammation and atherosclerosis. J Atheroscler Thromb 2010; 17:332-341.
    • (2010) J Atheroscler Thromb , vol.17 , pp. 332-341
    • Gustafson, B.1
  • 50
    • 60349095336 scopus 로고    scopus 로고
    • Exercise training decreases proinflammatory profile in Zucker diabetic (type 2) fatty rats
    • TEIXEIRA DE LEMOS E, REIS F, BAPTISTA S et al. Exercise training decreases proinflammatory profile in Zucker diabetic (type 2) fatty rats. Nutrition 2009; 25:330-339.
    • (2009) Nutrition , vol.25 , pp. 330-339
    • Teixeira De Lemos, E.1    Reis, F.2    Baptista, S.3
  • 52
    • 27744447352 scopus 로고    scopus 로고
    • Beneficial pleiotropic actions of melatonin in an experimental model of septic shock in mice: Regulation of pro-/anti-inflammatory cytokine network, protection against oxidative damage and antiapoptotic effects
    • CARRILLO-VICO A, LARDONE PJ, NAJI L et al. Beneficial pleiotropic actions of melatonin in an experimental model of septic shock in mice: regulation of pro-/anti-inflammatory cytokine network, protection against oxidative damage and antiapoptotic effects. J Pineal Res 2005; 39:400-408.
    • (2005) J Pineal Res , vol.39 , pp. 400-408
    • Carrillo-Vico, A.1    Lardone, P.J.2    Naji, L.3
  • 53
    • 0035204767 scopus 로고    scopus 로고
    • Effects of melatonin treatment in septic newborn
    • GITTO E, KABOWNIK M, REITER RJ et al. Effects of melatonin treatment in septic newborn. Pediatr Res 2001; 50:756-760.
    • (2001) Pediatr Res , vol.50 , pp. 756-760
    • Gitto, E.1    Kabownik, M.2    Reiter, R.J.3
  • 54
    • 68249102426 scopus 로고    scopus 로고
    • Melatonin reduces cardiac inflammatory injury induced by acute exercise
    • VENEROSO C, TUÑÓN MJ, GONZÁLEZ-GALLEGO J. Melatonin reduces cardiac inflammatory injury induced by acute exercise. J Pineal Res 2009; 47:184-191.
    • (2009) J Pineal Res , vol.47 , pp. 184-191
    • Veneroso, C.1    Tuñón, M.J.2    González-Gallego, J.3
  • 55
    • 80054822424 scopus 로고    scopus 로고
    • Melatonin supplementation ameliorates oxidative stress and inflammatory signaling induced by strenuous exercise in adult human males
    • OCHOA JJ, DIAZ-CASTRO J, JAJARABILLE N et al. Melatonin supplementation ameliorates oxidative stress and inflammatory signaling induced by strenuous exercise in adult human males. J Pineal Res 2011; 51:373-380.
    • (2011) J Pineal Res , vol.51 , pp. 373-380
    • Ochoa, J.J.1    Diaz-Castro, J.2    Jajarabille, N.3
  • 56
    • 17844391542 scopus 로고    scopus 로고
    • Behavioral treatments for chronic systemic inflammation: Effects of dietary weight loss and exercise training
    • NICKLAS BJ, YOU T, PAHOR M. Behavioral treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training. CMAJ 2005; 172:1199-1209.
    • (2005) CMAJ , vol.172 , pp. 1199-1209
    • Nicklas, B.J.1    You, T.2    Pahor, M.3
  • 57
    • 0037219409 scopus 로고    scopus 로고
    • Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction
    • EVANS JL, GOLDFINE ID, MADDUX BA et al. Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction. Diabetes 2003; 52:1-8.
    • (2003) Diabetes , vol.52 , pp. 1-8
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3
  • 58
    • 0032913309 scopus 로고    scopus 로고
    • Role of oxidative stress in diabetic complications: A new perspective on an old paradigm
    • BAYNES JW, THORPE SR. Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 1999; 48:1-9.
    • (1999) Diabetes , vol.48 , pp. 1-9
    • Baynes, J.W.1    Thorpe, S.R.2
  • 59
    • 1642562820 scopus 로고    scopus 로고
    • Regulation of antioxidant enzymes: A significant role for melatonin
    • RODRIGUEZ C, MAYO JC, SAINZ RM et al. Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 2004; 36:1-9.
    • (2004) J Pineal Res , vol.36 , pp. 1-9
    • Rodriguez, C.1    Mayo, J.C.2    Sainz, R.M.3
  • 60
    • 33845536018 scopus 로고    scopus 로고
    • One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species?
    • TAN DX, MANCHESTER LC, TERRON MP et al. One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? J Pineal Res 2007; 42:28-42.
    • (2007) J Pineal Res , vol.42 , pp. 28-42
    • Tan, D.X.1    Manchester, L.C.2    Terron, M.P.3
  • 61
    • 84856693660 scopus 로고    scopus 로고
    • Extrapineal melatonin: Analysis of its subcellular distribución and daily fluctuations
    • VENEGAS C, GARCIA JA, ESCAMES G et al. Extrapineal melatonin: Analysis of its subcellular distribución and daily fluctuations. J Pineal Res 2012; 52:217-227.
    • (2012) J Pineal Res , vol.52 , pp. 217-227
    • Venegas, C.1    Garcia, J.A.2    Escames, G.3
  • 62
    • 12944299790 scopus 로고    scopus 로고
    • A protective effect of adiponectin against oxidative stress in japanese americans: The association between adiponectin or leptin and urinary isoprostane
    • NAKANISHI S, YAMANE K, KAMEI N et al. A protective effect of adiponectin against oxidative stress in japanese americans: The association between adiponectin or leptin and urinary isoprostane. Metabolism 2005; 54:194-199.
    • (2005) Metabolism , vol.54 , pp. 194-199
    • Nakanishi, S.1    Yamane, K.2    Kamei, N.3
  • 63
    • 0035818556 scopus 로고    scopus 로고
    • Exploiting the vascular protective effects of high density lipoprotein and its apolipoproteins: An idea whose time for testing is coming, part i
    • SHAH PK, KAUL S, NILSSON J et al. Exploiting the vascular protective effects of high density lipoprotein and its apolipoproteins: an idea whose time for testing is coming, part I. Circulation 2001; 104: 2376-2383.
    • (2001) Circulation , vol.104 , pp. 2376-2383
    • Shah, P.K.1    Kaul, S.2    Nilsson, J.3
  • 64
    • 77953482835 scopus 로고    scopus 로고
    • Clinical uses of melatonin: Evaluation of human trials
    • SANCHEZ-BARCELO EJ, MEDIAVILLA MD, TAN DX et al. Clinical uses of melatonin: evaluation of human trials. Curr Med Chem 2010; 17: 2070-2095.
    • (2010) Curr Med Chem , vol.17 , pp. 2070-2095
    • Sanchez-Barcelo, E.J.1    Mediavilla, M.D.2    Tan, D.X.3
  • 65
    • 79953743149 scopus 로고    scopus 로고
    • Melatonin and the metabolic syndrome: Physiopathologic and therapeutical implications
    • CARDINALI DP, CANO P, JIMENEZ-ORTEGA V et al. Melatonin and the metabolic syndrome: physiopathologic and therapeutical implications. Neuroendocrinology 2011; 93:133-142.
    • (2011) Neuroendocrinology , vol.93 , pp. 133-142
    • Cardinali, D.P.1    Cano, P.2    Jimenez-Ortega, V.3
  • 66
    • 84860242302 scopus 로고    scopus 로고
    • Melatonin and the metabolic syndrome: A tool for effective therapy in obesity-associated abnormalities?
    • NDUHIRABANDI F, DU TOIT EF, LOCHNER A. Melatonin and the metabolic syndrome: a tool for effective therapy in obesity-associated abnormalities? Acta Physiol (Oxf) 2012; 205:209-223.
    • (2012) Acta Physiol (Oxf) , vol.205 , pp. 209-223
    • Nduhirabandi, F.1    Du Toit, E.F.2    Lochner, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.