메뉴 건너뛰기




Volumn 1, Issue , 2016, Pages 749-759

Cannabidiol and 5-HT1A Receptors

Author keywords

5HT1A receptors; Anxiety; Cannabidiol; Cannabis sativa; Depression; Motor control; Nausea; Neuroprotection; Phytocannabinoids; Serotonin

Indexed keywords


EID: 84969594450     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-800213-1.00070-5     Document Type: Chapter
Times cited : (8)

References (74)
  • 1
    • 0000506578 scopus 로고
    • Marihuana
    • Adams, R. (1941). Marihuana. Harvey Lectures, 37, 168-197.
    • (1941) Harvey Lectures , vol.37 , pp. 168-197
    • Adams, R.1
  • 2
    • 77954145403 scopus 로고    scopus 로고
    • Cannabidiol injected into the bed nucleus of the stria terminalis modulates baroreflex activity through 5-HT1A receptors
    • Alves, F. H., Crestani, C. C., Gomes, F. V., Guimarães, F. S., Correa, F. M., & Resstel, L. B. (2010). Cannabidiol injected into the bed nucleus of the stria terminalis modulates baroreflex activity through 5-HT1A receptors. Pharmacological Research, 62(3), 228-236.
    • (2010) Pharmacological Research , vol.62 , Issue.3 , pp. 228-236
    • Alves, F.H.1    Crestani, C.C.2    Gomes, F.V.3    Guimarães, F.S.4    Correa, F.M.5    Resstel, L.B.6
  • 3
    • 77955716188 scopus 로고    scopus 로고
    • Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus
    • Bambico, F. R., Cassano, T., Dominguez-Lopez, S., Katz, N., Walker, C. D., Piomelli, D., & Gobbi, G. (2010). Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus. Neuropsychopharmacology, 35(10), 2083-2100.
    • (2010) Neuropsychopharmacology , vol.35 , Issue.10 , pp. 2083-2100
    • Bambico, F.R.1    Cassano, T.2    Dominguez-Lopez, S.3    Katz, N.4    Walker, C.D.5    Piomelli, D.6    Gobbi, G.7
  • 4
    • 9844246446 scopus 로고    scopus 로고
    • Drugs acting upon the cyclic adenosine monophosphate/protein kinase A signalling pathway modulate memory consolidation when given late after training into rat hippocampus but not amygdala
    • Bevilaqua, L., Ardenghi, P., Schroder, N., Bromberg, E., Schmitz, P. K., Schaeffer, E., ... Izquierdo, I. (1997). Drugs acting upon the cyclic adenosine monophosphate/protein kinase A signalling pathway modulate memory consolidation when given late after training into rat hippocampus but not amygdala. Behavioural Pharmacology, 8(4), 331-338.
    • (1997) Behavioural Pharmacology , vol.8 , Issue.4 , pp. 331-338
    • Bevilaqua, L.1    Ardenghi, P.2    Schroder, N.3    Bromberg, E.4    Schmitz, P.K.5    Schaeffer, E.6    Izquierdo, I.7
  • 5
    • 0034751335 scopus 로고    scopus 로고
    • Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
    • Bisogno, T., Hanus, L., De Petrocellis, L., Tchilibon, S., Ponde, D. E., Brandi, I., ... Di Marzo, V. (2001). Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. British Journal of Pharmacology, 134(4), 845-852.
    • (2001) British Journal of Pharmacology , vol.134 , Issue.4 , pp. 845-852
    • Bisogno, T.1    Hanus, L.2    De Petrocellis, L.3    Tchilibon, S.4    Ponde, D.E.5    Brandi, I.6    Di Marzo, V.7
  • 7
    • 46649094780 scopus 로고    scopus 로고
    • Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats
    • Campos, A. C., & Guimarães, F. S. (2008). Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats. Psychopharmacology (Berlin), 199(2), 223-230.
    • (2008) Psychopharmacology (Berlin) , vol.199 , Issue.2 , pp. 223-230
    • Campos, A.C.1    Guimarães, F.S.2
  • 8
    • 71549171421 scopus 로고    scopus 로고
    • Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids
    • Campos, A. C., & Guimarães, F. S. (2009). Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 33(8), 1517-1521.
    • (2009) Progress in Neuro-Psychopharmacology & Biological Psychiatry , vol.33 , Issue.8 , pp. 1517-1521
    • Campos, A.C.1    Guimarães, F.S.2
  • 9
    • 84866942852 scopus 로고    scopus 로고
    • Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: possible involvement of 5HT1A receptors
    • Campos, A. C., Ferreira, F. R., & Guimarães, F. S. (2012). Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: possible involvement of 5HT1A receptors. Journal of Psychiatric Research, 46(11), 1501-1510.
    • (2012) Journal of Psychiatric Research , vol.46 , Issue.11 , pp. 1501-1510
    • Campos, A.C.1    Ferreira, F.R.2    Guimarães, F.S.3
  • 12
    • 84877156654 scopus 로고    scopus 로고
    • Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats
    • Campos, A. C., de Paula Soares, V., Carvalho, M. C., Ferreira, F. R., Vicente, M. A., Brandão, M. L., ... Guimarães, F. S. (2013). Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats. Psychopharmacology (Berlin), 226(1), 13-24.
    • (2013) Psychopharmacology (Berlin) , vol.226 , Issue.1 , pp. 13-24
    • Campos, A.C.1    de Paula Soares, V.2    Carvalho, M.C.3    Ferreira, F.R.4    Vicente, M.A.5    Brandão, M.L.6    Guimarães, F.S.7
  • 13
    • 77955168120 scopus 로고    scopus 로고
    • Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors
    • Casarotto, P. C., Gomes, F. V., Resstel, L. B., & Guimarães, F. S. (2010). Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors. Behavioural Pharmacology, 21(4), 353-358.
    • (2010) Behavioural Pharmacology , vol.21 , Issue.4 , pp. 353-358
    • Casarotto, P.C.1    Gomes, F.V.2    Resstel, L.B.3    Guimarães, F.S.4
  • 14
    • 79952282058 scopus 로고    scopus 로고
    • Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice
    • Cassano, T., Gaetani, S., Macheda, T., Laconca, L., Romano, A., Morgese, M. G., ... Piomelli, D. (2011). Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice. Psychopharmacology (Berlin), 214(2), 465-476.
    • (2011) Psychopharmacology (Berlin) , vol.214 , Issue.2 , pp. 465-476
    • Cassano, T.1    Gaetani, S.2    Macheda, T.3    Laconca, L.4    Romano, A.5    Morgese, M.G.6    Piomelli, D.7
  • 15
    • 7644226766 scopus 로고    scopus 로고
    • 5-HT activates ERK MAP kinase in cultured-human peripheral blood mononuclear cells via 5-HT1A receptors
    • Cloëz-Tayarani, I., Kayyali, U. S., Fanburg, B. L., & Cavaillon, J. M. (2004). 5-HT activates ERK MAP kinase in cultured-human peripheral blood mononuclear cells via 5-HT1A receptors. Life Science, 76(4), 429-443.
    • (2004) Life Science , vol.76 , Issue.4 , pp. 429-443
    • Cloëz-Tayarani, I.1    Kayyali, U.S.2    Fanburg, B.L.3    Cavaillon, J.M.4
  • 19
    • 84883026511 scopus 로고    scopus 로고
    • Motor effects of the non-psychotropic phytocannabinoid cannabidiol that are mediated by 5-HT1A receptors
    • Espejo-Porras, F., Fernández-Ruiz, J., Pertwee, R. G., Mechoulam, R., & García, C. (2013). Motor effects of the non-psychotropic phytocannabinoid cannabidiol that are mediated by 5-HT1A receptors. Neuropharmacology, 75, 155-163.
    • (2013) Neuropharmacology , vol.75 , pp. 155-163
    • Espejo-Porras, F.1    Fernández-Ruiz, J.2    Pertwee, R.G.3    Mechoulam, R.4    García, C.5
  • 20
    • 82655189157 scopus 로고    scopus 로고
    • Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARgamma involvement
    • Esposito, G., Scuderi, C., Valenza, M., Togna, G. I., Latina, V., De Filippis, D., ... Steardo, L. (2011). Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARgamma involvement. PLoS One, 6(12), e28668.
    • (2011) PLoS One , vol.6 , Issue.12 , pp. e28668
    • Esposito, G.1    Scuderi, C.2    Valenza, M.3    Togna, G.I.4    Latina, V.5    De Filippis, D.6    Steardo, L.7
  • 22
    • 84861993153 scopus 로고    scopus 로고
    • The endocannabinoid and endovanilloid systems interact in the rat prelimbic medial prefrontal cortex to control anxiety-like behavior
    • Fogaça, M. V., Aguiar, D. C., Moreira, F. A., & Guimarães, F. S. (2012). The endocannabinoid and endovanilloid systems interact in the rat prelimbic medial prefrontal cortex to control anxiety-like behavior. Neuropharmacology, 63(2), 202-210.
    • (2012) Neuropharmacology , vol.63 , Issue.2 , pp. 202-210
    • Fogaça, M.V.1    Aguiar, D.C.2    Moreira, F.A.3    Guimarães, F.S.4
  • 24
    • 84876473287 scopus 로고    scopus 로고
    • Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats
    • Fogaça, M. V., Gomes, F. V., Moreira, F. A., Guimarães, F. S., & Aguiar, D. C. (2013). Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats. Psychopharmacology (Berlin), 226(3), 579-587.
    • (2013) Psychopharmacology (Berlin) , vol.226 , Issue.3 , pp. 579-587
    • Fogaça, M.V.1    Gomes, F.V.2    Moreira, F.A.3    Guimarães, F.S.4    Aguiar, D.C.5
  • 25
    • 84894375170 scopus 로고    scopus 로고
    • Effects of intra-prelimbic prefrontal cortex injection of cannabidiol on anxiety-like behavior: involvement of 5HT1A receptors and previous stressful experience
    • Fogaça, M. V., Reis, F. M., Campos, A. C., & Guimarães, F. S. (2014). Effects of intra-prelimbic prefrontal cortex injection of cannabidiol on anxiety-like behavior: involvement of 5HT1A receptors and previous stressful experience. European Neuropsychopharmacology, 24(3), 410-419.
    • (2014) European Neuropsychopharmacology , vol.24 , Issue.3 , pp. 410-419
    • Fogaça, M.V.1    Reis, F.M.2    Campos, A.C.3    Guimarães, F.S.4
  • 26
    • 84872537290 scopus 로고    scopus 로고
    • Cannabinoid receptor agonists upregulate and enhance serotonin 2A (5-HT2A) receptor activity via ERK1/2 signaling
    • Franklin, J. M., & Carrasco, G. A. (2013). Cannabinoid receptor agonists upregulate and enhance serotonin 2A (5-HT2A) receptor activity via ERK1/2 signaling. Synapse, 67(3), 145-159.
    • (2013) Synapse , vol.67 , Issue.3 , pp. 145-159
    • Franklin, J.M.1    Carrasco, G.A.2
  • 27
    • 84880360557 scopus 로고    scopus 로고
    • Cannabidiol attenuates catalepsy induced by distinct pharmacological mechanisms via 5-HT1A receptor activation in mice
    • Gomes, F. V., Del Bel, E. A., & Guimarães, F. S. (2013). Cannabidiol attenuates catalepsy induced by distinct pharmacological mechanisms via 5-HT1A receptor activation in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 46, 43-47.
    • (2013) Progress in Neuro-Psychopharmacology & Biological Psychiatry , vol.46 , pp. 43-47
    • Gomes, F.V.1    Del Bel, E.A.2    Guimarães, F.S.3
  • 28
    • 84856432211 scopus 로고    scopus 로고
    • Cannabidiol injected into the bed nucleus of the stria terminalis reduces the expression of contextual fear conditioning via 5-HT1A receptors
    • Gomes, F. V., Reis, D. G., Alves, F. H., Corrêa, F. M., Guimarães, F. S., & Resstel, L. B. (2012). Cannabidiol injected into the bed nucleus of the stria terminalis reduces the expression of contextual fear conditioning via 5-HT1A receptors. Journal of Psychopharmacology, 26(1), 104-113.
    • (2012) Journal of Psychopharmacology , vol.26 , Issue.1 , pp. 104-113
    • Gomes, F.V.1    Reis, D.G.2    Alves, F.H.3    Corrêa, F.M.4    Guimarães, F.S.5    Resstel, L.B.6
  • 29
    • 79952486586 scopus 로고    scopus 로고
    • The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors
    • Gomes, F. V., Resstel, L. B., & Guimarães, F. S. (2011). The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors. Psychopharmacology (Berlin), 213(2-3), 465-473.
    • (2011) Psychopharmacology (Berlin) , vol.213 , Issue.2-3 , pp. 465-473
    • Gomes, F.V.1    Resstel, L.B.2    Guimarães, F.S.3
  • 31
    • 33847261953 scopus 로고    scopus 로고
    • Repeated treatment with cannabidiol but not delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance
    • Hayakawa, K., Mishima, K., Nozako, M., Ogata, A., Hazekawa, M., Liu, A. X., ... Fujiwara, M. (2007). Repeated treatment with cannabidiol but not delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance. Neuropharmacology, 52(4), 1079-1087.
    • (2007) Neuropharmacology , vol.52 , Issue.4 , pp. 1079-1087
    • Hayakawa, K.1    Mishima, K.2    Nozako, M.3    Ogata, A.4    Hazekawa, M.5    Liu, A.X.6    Fujiwara, M.7
  • 32
    • 56649122099 scopus 로고    scopus 로고
    • mu-Opioid receptor forms a functional heterodimer with cannabinoid CB1 receptor: electrophysiological and FRET assay analysis
    • Hojo, M., Sudo, Y., Ando, Y., Minami, K., Takada, M., Matsubara, T., & Uezono, Y. (2008). mu-Opioid receptor forms a functional heterodimer with cannabinoid CB1 receptor: electrophysiological and FRET assay analysis. Journal of Pharmaceutical Sciences, 108(3), 308-319.
    • (2008) Journal of Pharmaceutical Sciences , vol.108 , Issue.3 , pp. 308-319
    • Hojo, M.1    Sudo, Y.2    Ando, Y.3    Minami, K.4    Takada, M.5    Matsubara, T.6    Uezono, Y.7
  • 33
    • 60149102476 scopus 로고    scopus 로고
    • Delta9-tetrahydrocannabinol and cannabidiol modulate mitogen-induced tryptophan degradation and neopterin formation in peripheral blood mononuclear cells in vitro
    • Jenny, M., Santer, E., Pirich, E., Schennach, H., & Fuchs, D. (2009). Delta9-tetrahydrocannabinol and cannabidiol modulate mitogen-induced tryptophan degradation and neopterin formation in peripheral blood mononuclear cells in vitro. Journal of Neuroimmunology, 207(1-2), 75-82.
    • (2009) Journal of Neuroimmunology , vol.207 , Issue.1-2 , pp. 75-82
    • Jenny, M.1    Santer, E.2    Pirich, E.3    Schennach, H.4    Fuchs, D.5
  • 35
    • 84874413463 scopus 로고    scopus 로고
    • Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1A receptors in the dorsal raphe nucleus
    • Katsidoni, V., Anagnostou, I., & Panagis, G. (2013). Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1A receptors in the dorsal raphe nucleus. Addiction Biology, 18(2), 286-296.
    • (2013) Addiction Biology , vol.18 , Issue.2 , pp. 286-296
    • Katsidoni, V.1    Anagnostou, I.2    Panagis, G.3
  • 37
    • 41149147486 scopus 로고    scopus 로고
    • Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus
    • Ludanyi, A., Eross, L., Czirjak, S., Vajda, J., Halasz, P., Watanabe, M., ... Katona, I. (2008). Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus. Journal of Neuroscience, 28(12), 2976-2990.
    • (2008) Journal of Neuroscience , vol.28 , Issue.12 , pp. 2976-2990
    • Ludanyi, A.1    Eross, L.2    Czirjak, S.3    Vajda, J.4    Halasz, P.5    Watanabe, M.6    Katona, I.7
  • 38
    • 77249134168 scopus 로고    scopus 로고
    • Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation
    • Magen, I., Avraham, Y., Ackerman, Z., Vorobiev, L., Mechoulam, R., & Berry, E. M. (2010). Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation. British Journal of Pharmacology, 159(4), 950-957.
    • (2010) British Journal of Pharmacology , vol.159 , Issue.4 , pp. 950-957
    • Magen, I.1    Avraham, Y.2    Ackerman, Z.3    Vorobiev, L.4    Mechoulam, R.5    Berry, E.M.6
  • 41
    • 0013768939 scopus 로고
    • The structure of cannabidiol
    • Mechoulam, R., & Shvo, Y. (1963). The structure of cannabidiol. Tetrahedron, 19, 2073-2078.
    • (1963) Tetrahedron , vol.19 , pp. 2073-2078
    • Mechoulam, R.1    Shvo, Y.2
  • 42
    • 18244396915 scopus 로고    scopus 로고
    • Cannabidiol prevents cerebral infarction via a serotonergic 5-hydroxytryptamine1A receptor-dependent mechanism
    • Mishima, K., Hayakawa, K., Abe, K., Ikeda, T., Egashira, N., Iwasaki, K., & Fujiwara, M. (2005). Cannabidiol prevents cerebral infarction via a serotonergic 5-hydroxytryptamine1A receptor-dependent mechanism. Stroke, 36(5), 1077-1082.
    • (2005) Stroke , vol.36 , Issue.5 , pp. 1077-1082
    • Mishima, K.1    Hayakawa, K.2    Abe, K.3    Ikeda, T.4    Egashira, N.5    Iwasaki, K.6    Fujiwara, M.7
  • 43
    • 84878345442 scopus 로고    scopus 로고
    • Cannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings
    • Morgan, C. J., Das, R. K., Joye, A., Curran, H. V., & Kamboj, S. K. (2013). Cannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings. Addictive Behaviors, 38(9), 2433-2436.
    • (2013) Addictive Behaviors , vol.38 , Issue.9 , pp. 2433-2436
    • Morgan, C.J.1    Das, R.K.2    Joye, A.3    Curran, H.V.4    Kamboj, S.K.5
  • 46
    • 5444220592 scopus 로고    scopus 로고
    • Effect of low doses of delta9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats
    • Parker, L. A., Burton, P., Sorge, R. E., Yakiwchuk, C., & Mechoulam, R. (2004). Effect of low doses of delta9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats. Psychopharmacology (Berlin), 175(3), 360-366.
    • (2004) Psychopharmacology (Berlin) , vol.175 , Issue.3 , pp. 360-366
    • Parker, L.A.1    Burton, P.2    Sorge, R.E.3    Yakiwchuk, C.4    Mechoulam, R.5
  • 47
    • 29144520207 scopus 로고    scopus 로고
    • Delta-9-tetrahydrocannabinol and cannabidiol, but not ondansetron, interfere with conditioned retching reactions elicited by a lithium-paired context in Suncus murinus: an animal model of anticipatory nausea and vomiting
    • Parker, L. A., Kwiatkowska, M., & Mechoulam, R. (2006). Delta-9-tetrahydrocannabinol and cannabidiol, but not ondansetron, interfere with conditioned retching reactions elicited by a lithium-paired context in Suncus murinus: an animal model of anticipatory nausea and vomiting. Physiology & Behavior, 87(1), 66-71.
    • (2006) Physiology & Behavior , vol.87 , Issue.1 , pp. 66-71
    • Parker, L.A.1    Kwiatkowska, M.2    Mechoulam, R.3
  • 49
    • 0018573963 scopus 로고
    • Multiple serotonin receptors: differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol
    • Peroutka, S. J., & Snyder, S. H. (1979). Multiple serotonin receptors: differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol. Molecular Pharmacology, 16(3), 687-699.
    • (1979) Molecular Pharmacology , vol.16 , Issue.3 , pp. 687-699
    • Peroutka, S.J.1    Snyder, S.H.2
  • 50
    • 77249112399 scopus 로고    scopus 로고
    • Ligand-induced regulation and localization of cannabinoid CB1 and dopamine D2L receptor heterodimers
    • Przybyla, J. A., & Watts, V. J. (2010). Ligand-induced regulation and localization of cannabinoid CB1 and dopamine D2L receptor heterodimers. Journal of Pharmacology and Experimental Therapeutics, 332(3), 710-719.
    • (2010) Journal of Pharmacology and Experimental Therapeutics , vol.332 , Issue.3 , pp. 710-719
    • Przybyla, J.A.1    Watts, V.J.2
  • 51
    • 46749129338 scopus 로고    scopus 로고
    • TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons
    • Qin, N., Neeper, M. P., Liu, Y., Hutchinson, T. L., Lubin, M. L., & Flores, C. M. (2008). TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. Journal of Neuroscience, 28(24), 6231-6238.
    • (2008) Journal of Neuroscience , vol.28 , Issue.24 , pp. 6231-6238
    • Qin, N.1    Neeper, M.P.2    Liu, Y.3    Hutchinson, T.L.4    Lubin, M.L.5    Flores, C.M.6
  • 52
    • 72449197981 scopus 로고    scopus 로고
    • Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
    • Ren, Y., Whittard, J., Higuera-Matas, A., Morris, C. V., & Hurd, Y. L. (2009). Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances. Journal of Neuroscience, 29(47), 14764-14769.
    • (2009) Journal of Neuroscience , vol.29 , Issue.47 , pp. 14764-14769
    • Ren, Y.1    Whittard, J.2    Higuera-Matas, A.3    Morris, C.V.4    Hurd, Y.L.5
  • 53
    • 65549106424 scopus 로고    scopus 로고
    • 5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats
    • Resstel, L. B., Tavares, R. F., Lisboa, S. F., Joça, S. R., Corrêa, F. M., & Guimarães, F. S. (2009). 5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats. British Journal of Pharmacology, 156(1), 181-188.
    • (2009) British Journal of Pharmacology , vol.156 , Issue.1 , pp. 181-188
    • Resstel, L.B.1    Tavares, R.F.2    Lisboa, S.F.3    Joça, S.R.4    Corrêa, F.M.5    Guimarães, F.S.6
  • 54
    • 0037189155 scopus 로고    scopus 로고
    • 5-HT1A receptor blockade and the motivational profile of ethanol
    • Risinger, F. O., & Boyce, J. M. (2002). 5-HT1A receptor blockade and the motivational profile of ethanol. Life Science, 71(6), 707-715.
    • (2002) Life Science , vol.71 , Issue.6 , pp. 707-715
    • Risinger, F.O.1    Boyce, J.M.2
  • 55
    • 83255165010 scopus 로고    scopus 로고
    • Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus
    • Rock, E. M., Bolognini, D., Limebeer, C. L., Cascio, M. G., Anavi-Goffer, S., Fletcher, P. J., ... Parker, L. A. (2012). Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus. British Journal of Pharmacology, 165(8), 2620-2634.
    • (2012) British Journal of Pharmacology , vol.165 , Issue.8 , pp. 2620-2634
    • Rock, E.M.1    Bolognini, D.2    Limebeer, C.L.3    Cascio, M.G.4    Anavi-Goffer, S.5    Fletcher, P.J.6    Parker, L.A.7
  • 56
    • 80052341043 scopus 로고    scopus 로고
    • Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews
    • Rock, E. M., Goodwin, J. M., Limebeer, C. L., Breuer, A., Pertwee, R. G., Mechoulam, R., & Parker, L. A. (2011). Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. Psychopharmacology (Berlin), 215(3), 505-512.
    • (2011) Psychopharmacology (Berlin) , vol.215 , Issue.3 , pp. 505-512
    • Rock, E.M.1    Goodwin, J.M.2    Limebeer, C.L.3    Breuer, A.4    Pertwee, R.G.5    Mechoulam, R.6    Parker, L.A.7
  • 57
    • 27644440716 scopus 로고    scopus 로고
    • Agonistic properties of cannabidiol at 5-HT1A receptors
    • Russo, E. B., Burnett, A., Hall, B., & Parker, K. K. (2005). Agonistic properties of cannabidiol at 5-HT1A receptors. Neurochemical Research, 30(8), 1037-1043.
    • (2005) Neurochemical Research , vol.30 , Issue.8 , pp. 1037-1043
    • Russo, E.B.1    Burnett, A.2    Hall, B.3    Parker, K.K.4
  • 58
    • 33749519562 scopus 로고    scopus 로고
    • Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia
    • Ryan, D., Drysdale, A. J., Pertwee, R. G., & Platt, B. (2006). Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia. Neuroscience Letters, 408(3), 236-241.
    • (2006) Neuroscience Letters , vol.408 , Issue.3 , pp. 236-241
    • Ryan, D.1    Drysdale, A.J.2    Pertwee, R.G.3    Platt, B.4
  • 59
    • 79551647321 scopus 로고    scopus 로고
    • Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists
    • Scopinho, A. A., Guimarães, F. S., Corrêa, F. M., & Resstel, L. B. (2011). Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists. Pharmacology Biochemistry and Behavior, 98(2), 268-272.
    • (2011) Pharmacology Biochemistry and Behavior , vol.98 , Issue.2 , pp. 268-272
    • Scopinho, A.A.1    Guimarães, F.S.2    Corrêa, F.M.3    Resstel, L.B.4
  • 60
    • 77953917373 scopus 로고    scopus 로고
    • Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors
    • Soares Vde, P., Campos, A. C., Bortoli, V. C., Zangrossi, H., Jr., Guimarães, F. S., & Zuardi, A. W. (2010). Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors. Behavioural Brain Research, 213(2), 225-229.
    • (2010) Behavioural Brain Research , vol.213 , Issue.2 , pp. 225-229
    • Soares Vde, P.1    Campos, A.C.2    Bortoli, V.C.3    Zangrossi, H.4    Guimarães, F.S.5    Zuardi, A.W.6
  • 61
    • 84863981429 scopus 로고    scopus 로고
    • On disruption of fear memory by reconsolidation blockade: evidence from cannabidiol treatment
    • Stern, C. A., Gazarini, L., Takahashi, R. N., Guimarães, F. S., & Bertoglio, L. J. (2012). On disruption of fear memory by reconsolidation blockade: evidence from cannabidiol treatment. Neuropsychopharmacology, 37(9), 2132-2142.
    • (2012) Neuropsychopharmacology , vol.37 , Issue.9 , pp. 2132-2142
    • Stern, C.A.1    Gazarini, L.2    Takahashi, R.N.3    Guimarães, F.S.4    Bertoglio, L.J.5
  • 62
    • 33746779447 scopus 로고    scopus 로고
    • The CB1 cannabinoid receptor mediates glutamatergic synaptic suppression in the hippocampus
    • Takahashi, K. A., & Castillo, P. E. (2006). The CB1 cannabinoid receptor mediates glutamatergic synaptic suppression in the hippocampus. Neuroscience, 139(3), 795-802.
    • (2006) Neuroscience , vol.139 , Issue.3 , pp. 795-802
    • Takahashi, K.A.1    Castillo, P.E.2
  • 63
    • 33847653702 scopus 로고    scopus 로고
    • Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro
    • Thomas, A., Baillie, G. L., Phillips, A. M., Razdan, R. K., Ross, R. A., & Pertwee, R. G. (2007). Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro. British Journal of Pharmacology, 150(5), 613-623.
    • (2007) British Journal of Pharmacology , vol.150 , Issue.5 , pp. 613-623
    • Thomas, A.1    Baillie, G.L.2    Phillips, A.M.3    Razdan, R.K.4    Ross, R.A.5    Pertwee, R.G.6
  • 64
    • 84865090466 scopus 로고    scopus 로고
    • Serotonin receptor, SERT mRNA and correlations with symptoms in males with alcohol dependence and suicide
    • Thompson, P. M., Cruz, D. A., Olukotun, D. Y., & Delgado, P. L. (2012). Serotonin receptor, SERT mRNA and correlations with symptoms in males with alcohol dependence and suicide. Acta Psychiatrica Scandinavica, 126(3), 165-174.
    • (2012) Acta Psychiatrica Scandinavica , vol.126 , Issue.3 , pp. 165-174
    • Thompson, P.M.1    Cruz, D.A.2    Olukotun, D.Y.3    Delgado, P.L.4
  • 65
    • 0003150924 scopus 로고
    • Hashish
    • Todd, A. R. (1946). Hashish. Experientia, 2, 55-60.
    • (1946) Experientia , vol.2 , pp. 55-60
    • Todd, A.R.1
  • 67
    • 84887829916 scopus 로고    scopus 로고
    • The role of 5-HT1A receptors in the anti-aversive effects of cannabidiol on panic attack-like behaviors evoked in the presence of the wild snake Epicrates cenchria crassus (Reptilia, Boidae)
    • Twardowschy, A., Castiblanco-Urbina, M. A., Uribe-Mariño, A., Biagioni, A. F., Salgado-Rohner, C. J., Crippa, J. A., & Coimbra, N. C. (2013). The role of 5-HT1A receptors in the anti-aversive effects of cannabidiol on panic attack-like behaviors evoked in the presence of the wild snake Epicrates cenchria crassus (Reptilia, Boidae). Journal of Psychopharmacology, 27(12), 1149-1159.
    • (2013) Journal of Psychopharmacology , vol.27 , Issue.12 , pp. 1149-1159
    • Twardowschy, A.1    Castiblanco-Urbina, M.A.2    Uribe-Mariño, A.3    Biagioni, A.F.4    Salgado-Rohner, C.J.5    Crippa, J.A.6    Coimbra, N.C.7
  • 69
    • 33846455132 scopus 로고    scopus 로고
    • TRPV1 receptor mediates glutamatergic synaptic input to dorsolateral periaqueductal gray (dl-PAG) neurons
    • Xing, J., & Li, J. (2007). TRPV1 receptor mediates glutamatergic synaptic input to dorsolateral periaqueductal gray (dl-PAG) neurons. Journal of Neurophysiology, 97(1), 503-511.
    • (2007) Journal of Neurophysiology , vol.97 , Issue.1 , pp. 503-511
    • Xing, J.1    Li, J.2
  • 70
    • 79956052822 scopus 로고    scopus 로고
    • Psychotropic and nonpsychotropic cannabis derivatives inhibit human 5-HT(3A) receptors through a receptor desensitization-dependent mechanism
    • Xiong, W., Koo, B. N., Morton, R., & Zhang, L. (2011). Psychotropic and nonpsychotropic cannabis derivatives inhibit human 5-HT(3A) receptors through a receptor desensitization-dependent mechanism. Neuroscience, 16(184), 28-37.
    • (2011) Neuroscience , vol.16 , Issue.184 , pp. 28-37
    • Xiong, W.1    Koo, B.N.2    Morton, R.3    Zhang, L.4
  • 71
    • 74549165354 scopus 로고    scopus 로고
    • Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors
    • Zanelati, T. V., Biojone, C., Moreira, F. A., Guimarães, F. S., & Joca, S. R. (2010). Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors. British Journal of Pharmacology, 159(1), 122-128.
    • (2010) British Journal of Pharmacology , vol.159 , Issue.1 , pp. 122-128
    • Zanelati, T.V.1    Biojone, C.2    Moreira, F.A.3    Guimarães, F.S.4    Joca, S.R.5
  • 73
    • 0020079139 scopus 로고
    • Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects
    • Zuardi, A. W., Shirakawa, I., Finkelfarb, E., & Karniol, I. G. (1982). Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects. Psychopharmacology (Berlin), 76(3), 245-250.
    • (1982) Psychopharmacology (Berlin) , vol.76 , Issue.3 , pp. 245-250
    • Zuardi, A.W.1    Shirakawa, I.2    Finkelfarb, E.3    Karniol, I.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.