Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Esposito, Giuseppe ^a   Scuderi, Caterina ^a   Valenza, Marta ^b   Togna, Giuseppina Ines ^a   Latina, Valentina ^a   de Filippis, Daniele ^c   Cipriano, Mariateresa ^c   Carratù, Maria Rosaria ^b   Iuvone, Teresa ^c   Steardo, Luca ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF BARI   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CANNABIDIOL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; NITRIC OXIDE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG EFFECT; DRUG RECEPTOR BINDING; GLIOSIS; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MALE; NERVE CELL LESION; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; NEUROTOXICITY; NEWBORN; NONHUMAN; RAT; ANIMAL; BINDING SITE; BRAIN; CYTOLOGY; METABOLISM; NERVE CELL; PATHOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SPRAGUE DAWLEY RAT; TIME;

AMYLOID BETA-PEPTIDES; ANIMALS; ASTROCYTES; BINDING SITES; BRAIN; CANNABIDIOL; HIPPOCAMPUS; INFLAMMATION; MALE; NEUROGENESIS; NEURONS; NITRIC OXIDE; PPAR GAMMA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 82655189157     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028668     Document Type: Article

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