Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats

Psychopharmacology

Volumn 226, Issue 3, 2013, Pages 579-587

  Fogaça, Manoela V ^a   Gomes, Felipe V ^a   Moreira, Fabrício A ^b   Guimarães, Francisco S ^a   Aguiar, Daniele C ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Anxiety; Defensive behavior; Endovanilloids; Glutamate

Indexed keywords

2 AMINO 7 PHOSPHONOHEPTANOIC ACID; ANANDAMIDE; CAPSAZEPINE; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; VANILLOID RECEPTOR 1 ANTAGONIST;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; EXPERIMENTAL TEST; MALE; MAZE TEST; NEUROTRANSMITTER RELEASE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; TAIL FLICK TEST; TRANQUILIZING ACTIVITY; VOGEL CONFLICT TEST;

2-AMINO-5-PHOSPHONOVALERATE; ANIMALS; ARACHIDONIC ACIDS; CANNABINOID RECEPTOR AGONISTS; CAPSAICIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCANNABINOIDS; MALE; MAZE LEARNING; PERIAQUEDUCTAL GRAY; POLYUNSATURATED ALKAMIDES; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; TRPV CATION CHANNELS;

EID: 84876473287     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-012-2927-2     Document Type: Article

References (58)

1. Aguiar DC, Guimaraes FS (2009) Blockade of NMDA receptors and nitric oxide synthesis in the dorsolateral periaqueductal gray attenuates behavioral and cellular responses of rats exposed to a live predator. J Neurosci Res 87:2418-2429
2. Aguiar DC, Moreira FA, Guimaraes FS (2006) Flight reactions induced by injection of glutamate N-methyl-d-aspartate receptor agonist into the rat dorsolateral periaqueductal gray are not dependent on endogenous nitric oxide. Pharmacol Biochem Behav 83:296-301
3. Aguiar DC, Terzian AL, Guimaraes FS, Moreira FA (2009) Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats. Psychopharmacol (Berl) 205:217-225
4. Bandler R, Keay KA, Floyd N, Price J (2000) Central circuits mediating patterned autonomic activity during active vs. passive emotional coping. Brain Res Bull 53:95-104
5. Bittencourt AS, Carobrez AP, Zamprogno LP, Tufik S, Schenberg LC (2004) Organization of single components of defensive behaviors within distinct columns of periaqueductal gray matter of the rat: role of N-methyl-d-aspartic acid glutamate receptors. Neuroscience 125:71-89
6. Campos AC, Guimaraes FS (2008) Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats. Psychopharmacol (Berl) 199:223-230
7. Carrive P (1993) The periaqueductal gray and defensive behavior: functional representation and neuronal organization. Behav Brain Res 58:27-47
8. Casarotto PC, Terzian AL, Aguiar DC, Zangrossi H, Guimaraes FS, Wotjak CT, Moreira FA (2012) Opposing roles for cannabinoid receptor type-1 (CB(1)) and transient receptor potential vanilloid type-1 channel (TRPV1) on the modulation of panic-like responses in rats. Neuropsychopharmacology 37:478-486
9. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816-824
10. Cavanaugh DJ, Chesler AT, Jackson AC, Sigal YM, Yamanaka H, Grant R, O'Donnell D, Nicoll RA, Shah NM, Julius D, Basbaum AI (2011) Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. J Neurosci 31:5067-5077
11. Clapham DE, Julius D, Montell C, Schultz G (2005) International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels. Pharmacol Rev 57:427-450
12. Cristino L, de Petrocellis L, Pryce G, Baker D, Guglielmotti V, Di Marzo V (2006) Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain. Neuroscience 139:1405-1415
13. Di Marzo V, Bisogno T, De Petrocellis L (2001) Anandamide: some like it hot. Trends Pharmacol Sci 22:346-349
14. File SE (1992) Behavioural detection of anxiolytic action. In: Elliot JM, Heal DJ, Marsden CA (eds) Experimental approaches to anxiety and depression. Wiley, New York, pp 25-44
15. Finn DP, Jhaveri MD, Beckett SR, Roe CH, Kendall DA, Marsden CA, Chapman V (2003) Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats. Neuropharmacology 45:594-604
16. Fogaca MV, Aguiar DC, Moreira FA, Guimaraes FS (2012) The endocannabinoid and endovanilloid systems interact in the rat prelimbic medial prefrontal cortex to control anxiety-like behavior. Neuropharmacology 63:202-210
17. Geller I, Seifter J (1960) The effects of meprobamate, barbiturate, damphetamine and promazine on experimentally induced conflict in the rat. Psychopharmacologia 1:482-492
18. Guimaraes FS, Carobrez AP, De Aguiar JC, Graeff FG (1991) Anxiolytic effect in the elevated plus-maze of the NMDA receptor antagonist AP7 microinjected into the dorsal periaqueductal grey. Psychopharmacol (Berl) 103:91-94
19. Guimaraes FS, Beijamini V, Moreira FA, Aguiar DC, de Lucca AC (2005) Role of nitric oxide in brain regions related to defensive reactions. Neurosci Biobehav Rev 29:1313-1322
20. Jin YH, Takemura M, Furuyama A, Yonehara N (2012) Peripheral glutamate receptors are required for hyperalgesia induced by capsaicin. Pain Res Treat 2012:915706
21. Kawahara H, Drew G, Christie M, Vaughan C (2011) Inhibition of fatty acid amide hydrolase unmasks CB(1) receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. Br J Pharmacol 163:1214-1222
22. Lisboa SF, Guimaraes FS (2012) Differential role of CB1 and TRPV1 receptors on anandamide modulation of defensive responses induced by nitric oxide in the dorsolateral periaqueductal gray. Neuropharmacology 62:2455-2462
23. Lisboa SF, Resstel LB, Aguiar DC, Guimaraes FS (2008) Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test. Eur J Pharmacol 593:73-78
24. Maione S, Bisogno T, de Novellis V, Palazzo E, Cristino L, Valenti M, Petrosino S, Guglielmotti V, Rossi F, Di Marzo V (2006) Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors. J Pharmacol Exp Ther 316:969-982
25. Maione S, Cristino L, Migliozzi AL, Georgiou AL, Starowicz K, Salt TE, Di Marzo V (2009) TRPV1 channels control synaptic plasticity in the developing superior colliculus. J Physiol 587:2521-2535
26. Marinelli S, Vaughan CW, Christie MJ, Connor M (2002) Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus in vitro. J Physiol 543:531-540
27. Marinelli S, Di Marzo V, Berretta N, Matias I, Maccarrone M, Bernardi G, Mercuri NB (2003) Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors. J Neurosci 23:3136-3144
28. Marsch R, Foeller E, Rammes G, Bunck M, Kossl M, Holsboer F, Zieglgansberger W, Landgraf R, Lutz B, Wotjak CT (2007) Reduced anxiety, conditioned fear, and hippocampal long-term potentiation in transient receptor potential vanilloid type 1 receptor-deficient mice. J Neurosci 27:832-839
29. Matheus MG, Guimaraes FS (1997) Antagonism of non-NMDA receptors in the dorsal periaqueductal grey induces anxiolytic effect in the elevated plus maze. Psychopharmacol (Berl) 132:14-18
30. McGaraughty S, Chu KL, Bitner RS, Martino B, El Kouhen R, Han P, Nikkel AL, Burgard EC, Faltynek CR, Jarvis MF (2003) Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM. J Neurophysiol 90:2702-2710
31. McGregor IS, Hargreaves GA, Apfelbach R, Hunt GE (2004) Neural correlates of cat odor-induced anxiety in rats: region-specific effects of the benzodiazepine midazolam. J Neurosci 24:4134-4144
32. Molchanov ML, Guimaraes FS (2002) Anxiolytic-like effects of AP7 injected into the dorsolateral or ventrolateral columns of the periaqueductal gray of rats. Psychopharmacol (Berl) 160:30-38
33. Moreira FA, Aguiar DC, Guimaraes FS (2006) Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test. Prog Neuropsychopharmacol Biol Psychiatry 30:1466-1471
34. Moreira FA, Aguiar DC, Guimaraes FS (2007) Anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaqueductal gray. Neuropharmacology 52:958-965
35. Moreira FA, Aguiar DC, Terzian AL, Guimaraes FS, Wotjak CT (2012) Cannabinoid type 1 receptors and transient receptor potential vanilloid type 1 channels in fear and anxiety-two sides of one coin? Neuroscience 204:186-192
36. Palazzo E, Marabese I, de Novellis V, Oliva P, Rossi F, Berrino L, Maione S (2001) Metabotropic and NMDA glutamate receptors participate in the cannabinoid-induced antinociception. Neuropharmacology 40:319-326
37. Palazzo E, de Novellis V, Marabese I, Cuomo D, Rossi F, Berrino L, Rossi F, Maione S (2002) Interaction between vanilloid and glutamate receptors in the central modulation of nociception. Eur J Pharmacol 439:69-75
38. Palazzos E, de Novellis V, Marabese I, Rossi F, Maione S (2006) Metabotropic glutamate and cannabinoid receptor crosstalk in periaqueductal grey pain processing. Curr Neuropharmacol 4:225-231
39. Paxinos G, Watson C (1997) The rat brain in stereotaxic coordinates, 3rd edn. Academic Press, New York
40. Paxinos G, Watson C (2007) The rat brain in stereotaxic coordinates, 6th edn. Academic Press/Elsevier, London
41. Pellow S, File SE (1986) Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat. Pharmacol Biochem Behav 24:525-529
42. Pertwee RG (2006) The pharmacology of cannabinoid receptors and their ligands: an overview. Int J Obes (Lond) 30(Suppl 1):S13-S18
43. Ross RA (2003) Anandamide and vanilloid TRPV1 receptors. Br J Pharmacol 140:790-801
44. Rubino T, Realini N, Castiglioni C, Guidali C, Vigano D, Marras E, Petrosino S, Perletti G, Maccarrone M, Di Marzo V, Parolaro D (2008) Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex. Cereb Cortex 18:1292-1301
45. Santos CJ, Stern CA, Bertoglio LJ (2008) Attenuation of anxiety-related behaviour after the antagonism of transient receptor potential vanilloid type 1 channels in the rat ventral hippocampus. Behav Pharmacol 19:357-360
46. Smart D, Jerman JC (2000) Anandamide: an endogenous activator of the vanilloid receptor. Trends Pharmacol Sci 21:134
47. Starowicz K, Maione S, Cristino L, Palazzo E, Marabese I, Rossi F, de Novellis V, Di Marzo V (2007) Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways. J Neurosci 27:13739-13749
48. Terzian AL, Aguiar DC, Guimaraes FS, Moreira FA (2009) Modulation of anxiety-like behaviour by Transient Receptor Potential Vanilloid Type 1 (TRPV1) channels located in the dorsolateral periaqueductal gray. Eur Neuropsychopharmacol 19:188-195
49. Toth A, Boczan J, Kedei N, Lizanecz E, Bagi Z, Papp Z, Edes I, Csiba L, Blumberg PM (2005) Expression and distribution of vanilloid receptor 1 (TRPV1) in the adult rat brain. Brain Res Mol Brain Res 135:162-168
50. Urban L, Dray A (1992) Synaptic activation of dorsal horn neurons by selective C-fibre excitation with capsaicin in the mouse spinal cord in vitro. Neuroscience 47:693-702
51. Urban L, Willetts J, Randic M, Papka RE (1985) The acute and chronic effects of capsaicin on slow excitatory transmission in rat dorsal horn. Brain Res 330:390-396
52. Vaughan CW, Connor M, Bagley EE, Christie MJ (2000) Actions of cannabinoids on membrane properties and synaptic transmission in rat periaqueductal gray neurons in vitro. Mol Pharmacol 57:288-295
53. Viveros MP, Marco EM, Llorente R, Lopez-Gallardo M (2007) Endocannabinoid system and synaptic plasticity: implications for emotional responses. Neural Plast 2007:52908
54. Walker JM, Huang SM, Strangman NM, Tsou K, Sanudo-Pena MC (1999) Pain modulation by release of the endogenous cannabinoid anandamide. Proc Natl Acad Sci USA 96:12198-12203
55. Xing J, Li J (2007) TRPV1 receptor mediates glutamatergic synaptic input to dorsolateral periaqueductal gray (dl-PAG) neurons. J Neurophysiol 97:503-511
56. You IJ, Jung YH, Kim MJ, Kwon SH, Hong SI, Lee SY, Jang CG (2012) Alterations in the emotional and memory behavioral phenotypes of transient receptor potential vanilloid type 1-deficient mice are mediated by changes in expression of 5-HT(1A), GABA(A), and NMDA receptors. Neuropharmacology 62:1034-1043
57. Zhou HY, Chen SR, Chen H, Pan HL (2009) The glutamatergic nature of TRPV1-expressing neurons in the spinal dorsal horn. J Neurochem 108:305-318
58. Zygmunt PM, Julius I, Di Marzo I, Hogestatt ED (2000) Anandamide - the other side of the coin. Trends Pharmacol Sci 21:43-44