메뉴 건너뛰기




Volumn 17, Issue 5, 2016, Pages

A comparative analysis of genetic and epigenetic events of breast and ovarian cancer related to tumorigenesis

Author keywords

Breast cancer; Epigenetics; Ovarian cancer

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CARBOPLATIN; CISPLATIN; DNA METHYLTRANSFERASE 1; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; METHOTREXATE; MICRORNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; STROMAL CELL DERIVED FACTOR 1; TAMOXIFEN; TRANSCRIPTION FACTOR EZH2; TRASTUZUMAB; VINCRISTINE; HISTONE;

EID: 84969234290     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms17050759     Document Type: Review
Times cited : (45)

References (101)
  • 3
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network
    • Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 2012, 490, 61-70.
    • (2012) Nature , vol.490 , pp. 61-70
  • 4
    • 84898490259 scopus 로고    scopus 로고
    • BRCA 1/2-Mutation related and sporadic breast and ovarian cancers: More alike than different
    • CrossRef, PubMed
    • Burgess, M.; Puhalla, S. BRCA 1/2-Mutation related and sporadic breast and ovarian cancers: More alike than different. Front. Oncol. 2014, 4. [CrossRef] [PubMed]
    • (2014) Front. Oncol. , pp. 4
    • Burgess, M.1    Puhalla, S.2
  • 5
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Network
    • Cancer Genome Atlas Network. Integrated genomic analyses of ovarian carcinoma. Nature 2011, 474, 609-615.
    • (2011) Nature , vol.474 , pp. 609-615
  • 6
    • 84894520085 scopus 로고    scopus 로고
    • Sleeping giants: Emerging roles for cadherins in health and disease
    • CrossRef, PubMed
    • Sadeqzadeh, E.; de Bock, D.E.; Thorne, R.F. Sleeping giants: Emerging roles for cadherins in health and disease. Med. Res. Rev. 2014, 34, 190-221. [CrossRef] [PubMed]
    • (2014) Med. Res. Rev. , vol.34 , pp. 190-221
    • Sadeqzadeh, E.1    de Bock, D.E.2    Thorne, R.F.3
  • 11
    • 84992005830 scopus 로고    scopus 로고
    • Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination
    • CrossRef, PubMed
    • Gong, F.; Chiu, L.-Y.; Cox, B.; Aymard, F.; Clouaire, T.; Leung, J.W.; Cammarata, M.; Perez, M.; Agarwal, P.; Brodbelt, J.S.; et al. Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination. Genes Dev. 2015, 29, 197-211. [CrossRef] [PubMed]
    • (2015) Genes Dev. , vol.29 , pp. 197-211
    • Gong, F.1    Chiu, L.-Y.2    Cox, B.3    Aymard, F.4    Clouaire, T.5    Leung, J.W.6    Cammarata, M.7    Perez, M.8    Agarwal, P.9    Brodbelt, J.S.10
  • 12
    • 84907710593 scopus 로고    scopus 로고
    • Id proteins: Small molecules, mighty regulators
    • PubMed
    • Ling, F.; Kang, B.; Sun, X. Id proteins: Small molecules, mighty regulators. Curr. Top. Dev. Biol. 2014, 110, 189-216. [PubMed]
    • (2014) Curr. Top. Dev. Biol. , vol.110 , pp. 189-216
    • Ling, F.1    Kang, B.2    Sun, X.3
  • 13
    • 33846421673 scopus 로고    scopus 로고
    • Congenital hypothyroid femail pax8-deficient mice are infertile despite thyroid hormone replacement therapy
    • CrossRef, PubMed
    • Mittag, J.; Winterhager, E.; Bauer, K.; Grummer, R. Congenital hypothyroid femail pax8-deficient mice are infertile despite thyroid hormone replacement therapy. Endocrinology 2007, 148, 719-725. [CrossRef] [PubMed]
    • (2007) Endocrinology , vol.148 , pp. 719-725
    • Mittag, J.1    Winterhager, E.2    Bauer, K.3    Grummer, R.4
  • 15
    • 84930576745 scopus 로고    scopus 로고
    • The cancer COMPASS: Navigating the functions of MLL complexes in cancer
    • CrossRef, PubMed
    • Ford, D.J.; Dingwall, A.K. The cancer COMPASS: Navigating the functions of MLL complexes in cancer. Cancer Genet. 2015, 208, 178-191. [CrossRef] [PubMed]
    • (2015) Cancer Genet. , vol.208 , pp. 178-191
    • Ford, D.J.1    Dingwall, A.K.2
  • 16
    • 4444363371 scopus 로고    scopus 로고
    • The role of Tbx2 and Tbx3 in mammary development and tumorigenesis
    • CrossRef, PubMed
    • Rowley, M.; Grothey, E.; Couch, F.J. The role of Tbx2 and Tbx3 in mammary development and tumorigenesis. J. Mammary Gland Biol. Neoplasia 2004, 2, 109-118. [CrossRef] [PubMed]
    • (2004) J. Mammary Gland Biol. Neoplasia , vol.2 , pp. 109-118
    • Rowley, M.1    Grothey, E.2    Couch, F.J.3
  • 17
    • 84880252811 scopus 로고    scopus 로고
    • Loss of FMR2 further emphasizes the link between deregulation of immediate early response genes FOS and JUN and intellectual disability
    • CrossRef, PubMed
    • Melko, M.; Nguyen, L.S.; Shaw, M.; Jolly, L.; Bardoni, B.; Gecz, J. Loss of FMR2 further emphasizes the link between deregulation of immediate early response genes FOS and JUN and intellectual disability. Hum. Mol. Genet. 2013, 22, 2984-2991. [CrossRef] [PubMed]
    • (2013) Hum. Mol. Genet. , vol.22 , pp. 2984-2991
    • Melko, M.1    Nguyen, L.S.2    Shaw, M.3    Jolly, L.4    Bardoni, B.5    Gecz, J.6
  • 18
    • 84866752100 scopus 로고    scopus 로고
    • New insights into ovarian cancer pathology
    • CrossRef, PubMed
    • Prat, J. New insights into ovarian cancer pathology. Ann. Oncol. 2012, 23, x111-x117. [CrossRef] [PubMed]
    • (2012) Ann. Oncol. , vol.23 , pp. x111-x117
    • Prat, J.1
  • 20
    • 77955363995 scopus 로고    scopus 로고
    • TP53 mutations in human cancers: Origins, consequences, and clinical use
    • CrossRef, PubMed
    • Olivier, M.; Hollstein, M.; Hainaut, P. TP53 mutations in human cancers: Origins, consequences, and clinical use. Cold Spring Harb. Perspect. Biol. 2010, 2, a001008. [CrossRef] [PubMeds]
    • (2010) Cold Spring Harb. Perspect. Biol. , vol.2
    • Olivier, M.1    Hollstein, M.2    Hainaut, P.3
  • 21
    • 3042784081 scopus 로고    scopus 로고
    • Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma
    • CrossRef, PubMed
    • Wang, Y.; Kringen, P.; Kristensen, G.B.; Holm, R.; Baekelandt, M.M.O.; Olivier, M.; Skomedal, H.; Hainaut, P.; Tropé, C.G.; Abeler, V.M.; et al. Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma. Hum. Mutat. 2004, 24, 21-34. [CrossRef] [PubMed]
    • (2004) Hum. Mutat. , vol.24 , pp. 21-34
    • Wang, Y.1    Kringen, P.2    Kristensen, G.B.3    Holm, R.4    Baekelandt, M.M.O.5    Olivier, M.6    Skomedal, H.7    Hainaut, P.8    Tropé, C.G.9    Abeler, V.M.10
  • 22
    • 0034676455 scopus 로고    scopus 로고
    • Surfing the p53 network
    • CrossRef, PubMed
    • Vogelstein, B.; Lane, D.; Levine, A.J. Surfing the p53 network. Nature 2000, 408, 307-310. [CrossRef] [PubMed]
    • (2000) Nature , vol.408 , pp. 307-310
    • Vogelstein, B.1    Lane, D.2    Levine, A.J.3
  • 23
    • 34249941944 scopus 로고    scopus 로고
    • Hereditary Ovarian Cancer Clinical Study Group. Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 mutation
    • CrossRef, PubMed
    • Finch, A.; Beiner, M.; Lubinski, J.; Lynch, H.T.; Moller, P.; Rosen, B.; Murphy, J.; Ghadirian, P.; Friedman, E.; Foulkes, W.D.; et al. Hereditary Ovarian Cancer Clinical Study Group. Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 mutation. JAMA 2006, 296, 185-192. [CrossRef] [PubMed]
    • (2006) JAMA , vol.296 , pp. 185-192
    • Finch, A.1    Beiner, M.2    Lubinski, J.3    Lynch, H.T.4    Moller, P.5    Rosen, B.6    Murphy, J.7    Ghadirian, P.8    Friedman, E.9    Foulkes, W.D.10
  • 26
    • 84926505383 scopus 로고    scopus 로고
    • Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype
    • University of Washington Centre for Mendelian Genomics; FORGE Canada Consortium, CrossRef, PubMed
    • Sawyer, S.L.; Tian, L.; Kähkönen, M.; Schwartzentruber, J.; Kircher, M.; University of Washington Centre for Mendelian Genomics; FORGE Canada Consortium; Majewski, J.; Dyment, D.A.; Innes, A.M.; et al. Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype. Cancer Discov. 2015, 5, 135-142. [CrossRef] [PubMed]
    • (2015) Cancer Discov. , vol.5 , pp. 135-142
    • Sawyer, S.L.1    Tian, L.2    Kähkönen, M.3    Schwartzentruber, J.4    Kircher, M.5    Majewski, J.6    Dyment, D.A.7    Innes, A.M.8
  • 27
    • 84942193303 scopus 로고    scopus 로고
    • BRCA1-line signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential
    • CrossRef, PubMed
    • Severson, T.M.; Peeters, J.; Majewski, I.; Michaut, M.; Bosma, A.; Schouten, P.C.; Chin, S.F.; Pereira, B.; Goldgraben, M.A.; Bismeijer, T.; et al. BRCA1-line signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential. Mol. Oncol. 2015, 9, 1529-1538. [CrossRef] [PubMed]
    • (2015) Mol. Oncol. , vol.9 , pp. 1529-1538
    • Severson, T.M.1    Peeters, J.2    Majewski, I.3    Michaut, M.4    Bosma, A.5    Schouten, P.C.6    Chin, S.F.7    Pereira, B.8    Goldgraben, M.A.9    Bismeijer, T.10
  • 28
    • 80054960864 scopus 로고    scopus 로고
    • Quantitative copy number analysis by Multiplex Ligation-dependent Probe Amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness
    • CrossRef, PubMed
    • Lips, E.H.; Laddach, N.; Savola, S.P.; Vollebergh, M.A.; Oonk, A.M.; Imholz, A.L.; Wessels, L.F.; Wesseling, J.; Nederlof, P.M.; Rodenhuis, S. Quantitative copy number analysis by Multiplex Ligation-dependent Probe Amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness. Breast Cancer Res. 2011, 13, R107. [CrossRef] [PubMed]
    • (2011) Breast Cancer Res. , vol.13 , pp. 107
    • Lips, E.H.1    Laddach, N.2    Savola, S.P.3    Vollebergh, M.A.4    Oonk, A.M.5    Imholz, A.L.6    Wessels, L.F.7    Wesseling, J.8    Nederlof, P.M.9    Rodenhuis, S.10
  • 32
    • 80755144048 scopus 로고    scopus 로고
    • Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase
    • CrossRef, PubMed
    • Derfoul, A.; Juan, A.H.; Difilippantonio, M.J.; Palanisamy, N.; Ried, T.; Sartorelli, V. Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase. Carcinogenesis 2011, 32, 1607-1614. [CrossRef] [PubMed]
    • (2011) Carcinogenesis , vol.32 , pp. 1607-1614
    • Derfoul, A.1    Juan, A.H.2    Difilippantonio, M.J.3    Palanisamy, N.4    Ried, T.5    Sartorelli, V.6
  • 33
    • 77955591555 scopus 로고    scopus 로고
    • MicroRNAs and their target gene networks in breast cancer
    • CrossRef, PubMed
    • O’Day, E.; Lal, A. MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res. 2010, 12, 201. [CrossRef] [PubMed]
    • (2010) Breast Cancer Res. , vol.12 , pp. 201
    • O’Day, E.1    Lal, A.2
  • 34
    • 84880570961 scopus 로고    scopus 로고
    • microRNA-antagonism regulates breast cancer stemness and metastasis via TET family dependent chromatin remodeling
    • CrossRef, PubMed
    • Song, S.J.; Poliseno, L.; Song, M.S.; Ala, U.; Webster, K.; Ng, C.; Beringer, G.; Brikbak, N.J.; Yuan, X.; Cantley, L.C.; et al. microRNA-antagonism regulates breast cancer stemness and metastasis via TET family dependent chromatin remodeling. Cell 2013, 154, 311-324. [CrossRef] [PubMed]
    • (2013) Cell , vol.154 , pp. 311-324
    • Song, S.J.1    Poliseno, L.2    Song, M.S.3    Ala, U.4    Webster, K.5    Ng, C.6    Beringer, G.7    Brikbak, N.J.8    Yuan, X.9    Cantley, L.C.10
  • 36
    • 84855279252 scopus 로고    scopus 로고
    • MicroRNA 34c gene down-regulation via DNA methylation promotes self-renewal and epithelial-mesenchymal transition in breast tumor-initiating cells
    • CrossRef, PubMed
    • Yu, F.; Jiao, Y.; Zhu, Y.;Wang, Y.; Zhu, J.; Cui, X.; Liu, Y.; He, Y.; Park, E.-Y.; Zhang, H.; et al. MicroRNA 34c gene down-regulation via DNA methylation promotes self-renewal and epithelial-mesenchymal transition in breast tumor-initiating cells. J. Biol. Chem. 2012, 287, 465-473. [CrossRef] [PubMed]
    • (2012) J. Biol. Chem. , vol.287 , pp. 465-473
    • Yu, F.1    Jiao, Y.2    Zhu, Y.3    Wang, Y.4    Zhu, J.5    Cui, X.6    Liu, Y.7    He, Y.8    Park, E.-Y.9    Zhang, H.10
  • 37
    • 39049086391 scopus 로고    scopus 로고
    • MicroRNA expression profiling in human ovarian cancer: MiR-214 induces cell survival and cisplatin resistance by targeting PTEN
    • CrossRef, PubMed
    • Yang, H.; Kong, W.; He, L.; Zhao, J.-J.; O’Donnell, J.D.; Wang, J.; Wenham, R.M.; Coppola, D.; Kruk, P.A.; Nicosia, S.V.; et al. MicroRNA expression profiling in human ovarian cancer: MiR-214 induces cell survival and cisplatin resistance by targeting PTEN. Cancer Res. 2008, 68, 425-433. [CrossRef] [PubMed]
    • (2008) Cancer Res. , vol.68 , pp. 425-433
    • Yang, H.1    Kong, W.2    He, L.3    Zhao, J.-J.4    O’Donnell, J.D.5    Wang, J.6    Wenham, R.M.7    Coppola, D.8    Kruk, P.A.9    Nicosia, S.V.10
  • 38
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • CrossRef, PubMed
    • Park, S.-M.; Gaur, A.B.; Lengyel, E.; Peter, M.E. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev. 2008, 22, 894-907. [CrossRef] [PubMed]
    • (2008) Genes Dev. , vol.22 , pp. 894-907
    • Park, S.-M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 41
    • 34250843675 scopus 로고    scopus 로고
    • The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines
    • CrossRef, PubMed
    • Adams, B.D.; Furneaux, H.; White, B.A. The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. Mol. Endocrinol. 2007, 21, 1132-1147. [CrossRef] [PubMed]
    • (2007) Mol. Endocrinol. , vol.21 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3
  • 42
    • 84930917894 scopus 로고    scopus 로고
    • Potential role of miR-100 in cancer diagnosis, prognosis, and therapy
    • CrossRef, PubMed
    • Qin, C.; Huang, R.;Wang, Z. Potential role of miR-100 in cancer diagnosis, prognosis, and therapy. Tumor Biol. 2015, 36, 1403-1409. [CrossRef] [PubMed]
    • (2015) Tumor Biol. , vol.36 , pp. 1403-1409
    • Qin, C.1    Huang, R.2    Wang, Z.3
  • 43
    • 84947126839 scopus 로고    scopus 로고
    • MicroRNA-9 promotes tumorigenesis and mediates sensitivity to cisplatin in primary epithelial ovarian cancer
    • CrossRef, PubMed
    • Zhao, H.;Wei,W.; Sun, Y.; Gao, J.;Wang, Q.; Zheng, J. MicroRNA-9 promotes tumorigenesis and mediates sensitivity to cisplatin in primary epithelial ovarian cancer. Tumor Biol. 2015, 36, 6867-6873. [CrossRef] [PubMed]
    • (2015) Tumor Biol. , vol.36 , pp. 6867-6873
    • Zhao, H.1    Wei, W.2    Sun, Y.3    Gao, J.4    Wang, Q.5    Zheng, J.6
  • 44
    • 84928568039 scopus 로고    scopus 로고
    • miR-233 regulates adipogenic and osteogenic differentiation of mesenchymal stem cells through a C/EBPs/miR-233/FGFR2 regualtory feedback loop
    • CrossRef, PubMed
    • Guan, X.; Gao, Y.; Zhou, J.; Wang, J.; Zheng, F.; Guo, F.; Chang, A.; Li, X.; Wang, B. miR-233 regulates adipogenic and osteogenic differentiation of mesenchymal stem cells through a C/EBPs/miR-233/FGFR2 regualtory feedback loop. Stem Cells 2015, 33, 1589-1600. [CrossRef] [PubMed]
    • (2015) Stem Cells , vol.33 , pp. 1589-1600
    • Guan, X.1    Gao, Y.2    Zhou, J.3    Wang, J.4    Zheng, F.5    Guo, F.6    Chang, A.7    Li, X.8    Wang, B.9
  • 45
    • 84941942461 scopus 로고    scopus 로고
    • Expression of serum miR-200a, miR-200b, and miR-200c as candidate biomarkers in epithelial ovarian cancer and their associationwith clinicopathological features
    • CrossRef, PubMed
    • Zuberi, M.; Mir, R.; Das, J.; Ahmad, I.; Javid, J.; Yadav, P.; Masroor, M.; Ahmad, S.; Ray, P.C.; Saxena, A. Expression of serum miR-200a, miR-200b, and miR-200c as candidate biomarkers in epithelial ovarian cancer and their associationwith clinicopathological features. Clin. Transl. Oncol. 2015, 17, 779-787. [CrossRef] [PubMed]
    • (2015) Clin. Transl. Oncol. , vol.17 , pp. 779-787
    • Zuberi, M.1    Mir, R.2    Das, J.3    Ahmad, I.4    Javid, J.5    Yadav, P.6    Masroor, M.7    Ahmad, S.8    Ray, P.C.9    Saxena, A.10
  • 46
    • 85048808255 scopus 로고    scopus 로고
    • MicroRNA regulation of human breast cancer stem cells
    • CrossRef, PubMed
    • Shimono, Y.; Mukohyama, J.; Nakamura, S.; Minami, H. MicroRNA regulation of human breast cancer stem cells. J. Clin. Med. 2016, 5, 2. [CrossRef] [PubMed]
    • (2016) J. Clin. Med. , vol.5 , pp. 2
    • Shimono, Y.1    Mukohyama, J.2    Nakamura, S.3    Minami, H.4
  • 47
    • 84969212804 scopus 로고    scopus 로고
    • miR-203 functions as a tumor suppressor by inhibiting epithelial to mesenchymal transition in ovarian cancer
    • PubMed
    • Zhao, G.; Guo, Y.; Chen, Z.; Wang, Y.; Yang, C.; Dudas, A.; Du, Z.; Liu, W.; Zou, Y.; Szabo, E.; et al. miR-203 functions as a tumor suppressor by inhibiting epithelial to mesenchymal transition in ovarian cancer. J. Cancer Sci. Ther. 2015, 7, 34-43. [PubMed]
    • (2015) J. Cancer Sci. Ther. , vol.7 , pp. 34-43
    • Zhao, G.1    Guo, Y.2    Chen, Z.3    Wang, Y.4    Yang, C.5    Dudas, A.6    Du, Z.7    Liu, W.8    Zou, Y.9    Szabo, E.10
  • 49
    • 70350728790 scopus 로고    scopus 로고
    • The epidermal growth factor receptor responsive miR-125a represses mesenchymal morphology in ovarian cancer cells
    • CrossRef
    • Dahl, K.D.C.; Dahl, R.; Kruichak, J.N.; Hudson, L.G. The epidermal growth factor receptor responsive miR-125a represses mesenchymal morphology in ovarian cancer cells. Neoplasia 2009, 11, 1208-1215. [CrossRef]
    • (2009) Neoplasia , vol.11 , pp. 1208-1215
    • Dahl, K.D.C.1    Dahl, R.2    Kruichak, J.N.3    Hudson, L.G.4
  • 50
    • 84900403807 scopus 로고    scopus 로고
    • Do epigenetic drug treatments hold the key to killing cancer progenitor cells?
    • CrossRef, PubMed
    • Byler, S.; Sarkar, S. Do epigenetic drug treatments hold the key to killing cancer progenitor cells? Epigenomics 2014, 6, 161-165. [CrossRef] [PubMed]
    • (2014) Epigenomics , vol.6 , pp. 161-165
    • Byler, S.1    Sarkar, S.2
  • 51
  • 52
    • 84923066119 scopus 로고    scopus 로고
    • Genetic alterations of histone lysine methyltransferases and their significance in breast cancer
    • CrossRef, PubMed
    • Liu, L.; Kimball, S.; Liu, H.; Holowatyj, A.; Yang, Z.Q. Genetic alterations of histone lysine methyltransferases and their significance in breast cancer. Oncotarget 2014, 6, 2466-2482. [CrossRef] [PubMed]
    • (2014) Oncotarget , vol.6 , pp. 2466-2482
    • Liu, L.1    Kimball, S.2    Liu, H.3    Holowatyj, A.4    Yang, Z.Q.5
  • 53
    • 85007071957 scopus 로고    scopus 로고
    • Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model
    • CrossRef, PubMed
    • Zhao, Q.Y.; Lei, P.J.; Zhang, X.; Zheng, J.Y.; Wang, H.Y.; Zhao, J.; Li, Y.M.; Ye, M.; Li, L.; Wei, G.; et al. Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model. Clin. Epigenet. 2016, 8, 34. [CrossRef] [PubMed]
    • (2016) Clin. Epigenet. , vol.8 , pp. 34
    • Zhao, Q.Y.1    Lei, P.J.2    Zhang, X.3    Zheng, J.Y.4    Wang, H.Y.5    Zhao, J.6    Li, Y.M.7    Ye, M.8    Li, L.9    Wei, G.10
  • 54
    • 84904604801 scopus 로고    scopus 로고
    • Histones and Their Modifications in Ovarian Cancer-Drivers of Disease and Therapeutic Targets
    • PubMed
    • Marsh, D.J.; Shah, J.S.; Cole, A.J. Histones and Their Modifications in Ovarian Cancer-Drivers of Disease and Therapeutic Targets. Front. Oncol. 2014, 4, 144. [PubMed]
    • (2014) Front. Oncol. , vol.4 , pp. 144
    • Marsh, D.J.1    Shah, J.S.2    Cole, A.J.3
  • 55
    • 84900391269 scopus 로고    scopus 로고
    • Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells
    • CrossRef, PubMed
    • Rhie, S.K.; Hazelett, D.J.; Coetzee, S.G.; Yan, C.; Noushmehr, H.; Coetzee, G.A. Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells. BMC Genom. 2014, 15, 331. [CrossRef] [PubMed]
    • (2014) BMC Genom. , vol.15 , pp. 331
    • Rhie, S.K.1    Hazelett, D.J.2    Coetzee, S.G.3    Yan, C.4    Noushmehr, H.5    Coetzee, G.A.6
  • 56
    • 79955513100 scopus 로고    scopus 로고
    • Aberrations of EZH2 in cancer
    • CrossRef, PubMed
    • Chase, A.; Cross, N.C.P. Aberrations of EZH2 in cancer. Clin. Cancer Res. 2011, 17, 2613-2618. [CrossRef] [PubMed]
    • (2011) Clin. Cancer Res. , vol.17 , pp. 2613-2618
    • Chase, A.1    Cross, N.C.P.2
  • 57
    • 84907391983 scopus 로고    scopus 로고
    • Enhancer altertions in cancer: A source for a cell identity crisis
    • CrossRef, PubMed
    • Kron, K.J.; Bailey, S.D.; Lupien, M. Enhancer altertions in cancer: A source for a cell identity crisis. Genome Med. 2014, 9, 77. [CrossRef] [PubMed]
    • (2014) Genome Med. , vol.9 , pp. 77
    • Kron, K.J.1    Bailey, S.D.2    Lupien, M.3
  • 58
    • 84947061003 scopus 로고    scopus 로고
    • Super enhancers in cancers, complex diseases, and developmental disorders
    • CrossRef, PubMed
    • Niederriter, A.R.; Varshney, A.; Parker, S.C.; Martin, D.M. Super enhancers in cancers, complex diseases, and developmental disorders. Genes (Basel) 2015, 4, 1183-1200. [CrossRef] [PubMed]
    • (2015) Genes (Basel) , vol.4 , pp. 1183-1200
    • Niederriter, A.R.1    Varshney, A.2    Parker, S.C.3    Martin, D.M.4
  • 61
    • 84874072228 scopus 로고    scopus 로고
    • Demethylation and re-expression of epigenetically silenced tumor suppressor genes: Sensitization of cancer cells by combination therapy
    • CrossRef, PubMed
    • Sarkar, S.; Goldgar, S.; Byler, S.; Rosenthal, S.; Heerboth, S. Demethylation and re-expression of epigenetically silenced tumor suppressor genes: Sensitization of cancer cells by combination therapy. Epigenomics 2013, 5, 87-94. [CrossRef] [PubMed]
    • (2013) Epigenomics , vol.5 , pp. 87-94
    • Sarkar, S.1    Goldgar, S.2    Byler, S.3    Rosenthal, S.4    Heerboth, S.5
  • 62
    • 84886257639 scopus 로고    scopus 로고
    • Cancer development, progression, and therapy: An epigenetic overview
    • CrossRef, PubMed
    • Sarkar, S.; Horn, G.; Moulton, K.; Oza, A.; Byler, S.; Kokolus, S.; Longacre, M. Cancer development, progression, and therapy: An epigenetic overview. Int. J. Mol. Sci. 2013, 14, 21087-21113. [CrossRef] [PubMed]
    • (2013) Int. J. Mol. Sci. , vol.14 , pp. 21087-21113
    • Sarkar, S.1    Horn, G.2    Moulton, K.3    Oza, A.4    Byler, S.5    Kokolus, S.6    Longacre, M.7
  • 63
    • 84901436722 scopus 로고    scopus 로고
    • DNA methylation profiles in ovarian cancer: Implication in diagnosis and therapy (Review)
    • CrossRef, PubMed
    • Koukoura, O.; Spandidos, D.A.; Daponte, A.; Sifakis, S. DNA methylation profiles in ovarian cancer: Implication in diagnosis and therapy (Review). Mol. Med. Rep. 2014, 10, 3-9. [CrossRef] [PubMed]
    • (2014) Mol. Med. Rep. , vol.10 , pp. 3-9
    • Koukoura, O.1    Spandidos, D.A.2    Daponte, A.3    Sifakis, S.4
  • 64
    • 84905817234 scopus 로고    scopus 로고
    • Strategies to overcome trastuzumab resistance in HER2-overexpressing breast cancers: Focus on new data from clinical trials
    • CrossRef, PubMed
    • Lavaud, P.; Andre, F. Strategies to overcome trastuzumab resistance in HER2-overexpressing breast cancers: Focus on new data from clinical trials. BMC Med. 2014, 12, 132. [CrossRef] [PubMed]
    • (2014) BMC Med. , vol.12 , pp. 132
    • Lavaud, P.1    Andre, F.2
  • 65
    • 55649100076 scopus 로고    scopus 로고
    • DNA hypermethylation, Her-2/neu overexpression and p53 mutations in ovarian carcinoma
    • CrossRef, PubMed
    • Feng, Q.; Deftereos, G. DNA hypermethylation, Her-2/neu overexpression and p53 mutations in ovarian carcinoma. Gynecol. Oncol. 2008, 111, 320-329. [CrossRef] [PubMed]
    • (2008) Gynecol. Oncol. , vol.111 , pp. 320-329
    • Feng, Q.1    Deftereos, G.2
  • 66
    • 31544435739 scopus 로고    scopus 로고
    • Breast cancer DNA methylation profiles in cancer cells and tumor stroma: Association with HER-2/neu status in primary breast cancer
    • CrossRef, PubMed
    • Fiegl, H.; Millinger, S.; Goebel, G.; Müller-Holzner, E.; Marth, C.; Laird, P.W.;Widschwendter, M. Breast cancer DNA methylation profiles in cancer cells and tumor stroma: Association with HER-2/neu status in primary breast cancer. Cancer Res. 2006, 66, 29-33. [CrossRef] [PubMed]
    • (2006) Cancer Res. , vol.66 , pp. 29-33
    • Fiegl, H.1    Millinger, S.2    Goebel, G.3    Müller-Holzner, E.4    Marth, C.5    Laird, P.W.6    Widschwendter, M.7
  • 67
    • 84905672549 scopus 로고    scopus 로고
    • Whole genome DNA methylation signature of HER2-positive breast cancer
    • CrossRef, PubMed
    • Lindqvist, B.M.; Wingren, S.; Motlagh, P.B.; Nilsson, T.K. Whole genome DNA methylation signature of HER2-positive breast cancer. Epigenetics 2014, 9, 1149-1162. [CrossRef] [PubMed]
    • (2014) Epigenetics , vol.9 , pp. 1149-1162
    • Lindqvist, B.M.1    Wingren, S.2    Motlagh, P.B.3    Nilsson, T.K.4
  • 68
    • 65849265065 scopus 로고    scopus 로고
    • Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays
    • CrossRef, PubMed
    • Rodenhiser, D.I.; Andrews, J.; Kennette, W.; Sadikovic, B.; Mendlowitz, A.; Tuck, A.B.; Chambers, A.F. Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays. Breast Cancer Res. 2008, 10. [CrossRef] [PubMed]
    • (2008) Breast Cancer Res. , pp. 10
    • Rodenhiser, D.I.1    Andrews, J.2    Kennette, W.3    Sadikovic, B.4    Mendlowitz, A.5    Tuck, A.B.6    Chambers, A.F.7
  • 70
    • 84904958086 scopus 로고    scopus 로고
    • Aberrant DNA methylation of integrin κ4 in human breast cancer
    • CrossRef, PubMed
    • Do, S.-I.; Ko, E.; Kang, S.Y.; Lee, J.E.; Nam, S.J.; Cho, E.Y.; Kim, D.-H. Aberrant DNA methylation of integrin κ4 in human breast cancer. Tumour Biol. 2014, 35, 7079-7084. [CrossRef] [PubMed]
    • (2014) Tumour Biol. , vol.35 , pp. 7079-7084
    • Do, S.-I.1    Ko, E.2    Kang, S.Y.3    Lee, J.E.4    Nam, S.J.5    Cho, E.Y.6    Kim, D.-H.7
  • 71
    • 84942062219 scopus 로고    scopus 로고
    • Interactions between κv-integrin and HER2 and their role in the invasive phenotype of breast cancer cells in vitro and in rat brain
    • CrossRef, PubMed
    • Lal, S.; Kersch, C.; Beeson, K.A.;Wu, Y.J.; Muldoon, L.L.; Neuwelt, E.A. Interactions between κv-integrin and HER2 and their role in the invasive phenotype of breast cancer cells in vitro and in rat brain. PLoS ONE 2015, 10, e0131842. [CrossRef] [PubMed]
    • (2015) PLoS ONE , vol.10
    • Lal, S.1    Kersch, C.2    Beeson, K.A.3    Wu, Y.J.4    Muldoon, L.L.5    Neuwelt, E.A.6
  • 72
    • 80051644174 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors reverse CpG methylation by regulating DNMT1 through ERK signaling
    • PubMed
    • Sarkar, S.; Abujamra, A.L.; Loew, J.E.; Forman, L.W.; Perrine, S.P.; Faller, D.V. Histone deacetylase inhibitors reverse CpG methylation by regulating DNMT1 through ERK signaling. Anticancer Res. 2011, 31, 2723-2732. [PubMed]
    • (2011) Anticancer Res. , vol.31 , pp. 2723-2732
    • Sarkar, S.1    Abujamra, A.L.2    Loew, J.E.3    Forman, L.W.4    Perrine, S.P.5    Faller, D.V.6
  • 74
    • 0034658196 scopus 로고    scopus 로고
    • Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells
    • CrossRef, PubMed
    • Robertson, K.D.; Keyomarsi, K.; Gonzales, F.A.; Velicescu, M.; Jones, P.A. Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells. Nucleic Acids Res. 2000, 28, 2108-2113. [CrossRef] [PubMed]
    • (2000) Nucleic Acids Res. , vol.28 , pp. 2108-2113
    • Robertson, K.D.1    Keyomarsi, K.2    Gonzales, F.A.3    Velicescu, M.4    Jones, P.A.5
  • 75
    • 85011957839 scopus 로고    scopus 로고
    • Methylation by DNMT1 is more Efficient in Chronic Lymphocytic Lymphoma Cells than in Normal Cells
    • CrossRef
    • Samorodnitsky, E.; Ghosh, E.; Mazumder, S.; Sarkar, S. Methylation by DNMT1 is more Efficient in Chronic Lymphocytic Lymphoma Cells than in Normal Cells. J. Proteom. Bioinform. 2014, 1. [CrossRef]
    • (2014) J. Proteom. Bioinform. , pp. 1
    • Samorodnitsky, E.1    Ghosh, E.2    Mazumder, S.3    Sarkar, S.4
  • 76
    • 84957426038 scopus 로고    scopus 로고
    • The roles of ncRNAs and histone-modifiers in regulating breast cancer stem cells
    • CrossRef, PubMed
    • Zhao, Z.; Li, S.; Song, E.; Liu, S. The roles of ncRNAs and histone-modifiers in regulating breast cancer stem cells. Protein Cell 2016, 7, 89-99. [CrossRef] [PubMed]
    • (2016) Protein Cell , vol.7 , pp. 89-99
    • Zhao, Z.1    Li, S.2    Song, E.3    Liu, S.4
  • 77
    • 33750798741 scopus 로고    scopus 로고
    • The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
    • CrossRef, PubMed
    • Yang, G.; Rosen, D.G.; Zhang, Z.; Bast, R.C.; Mills, G.B.; Colacino, J.A.; Mercado-Uribe, I.; Liu, J. The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis. Proc. Natl. Acad. Sci. USA 2006, 103, 16472-16477. [CrossRef] [PubMed]
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16472-16477
    • Yang, G.1    Rosen, D.G.2    Zhang, Z.3    Bast, R.C.4    Mills, G.B.5    Colacino, J.A.6    Mercado-Uribe, I.7    Liu, J.8
  • 78
    • 84887458997 scopus 로고    scopus 로고
    • A critical review of cost-effectiveness analyses of vaccinating males against human papillomavirus
    • CrossRef
    • Jiang, Y.; Gauthier, A.; Postma, M.J.; Ribassin-Majed, L.; Largeron, N.; Bresse, X. A critical review of cost-effectiveness analyses of vaccinating males against human papillomavirus. Hum. Vaccines Immunother. 2013, 9, 2285-2295. [CrossRef]
    • (2013) Hum. Vaccines Immunother. , vol.9 , pp. 2285-2295
    • Jiang, Y.1    Gauthier, A.2    Postma, M.J.3    Ribassin-Majed, L.4    Largeron, N.5    Bresse, X.6
  • 79
    • 79951988792 scopus 로고    scopus 로고
    • Activity of sorafenib in recurrent ovarian cancer and primary peritoneal carcinomatosis: A gynecologic oncology group trial
    • CrossRef, PubMed
    • Matei, D.; Sill, M.W.; Lankes, H.A.; DeGeest, K.; Bristow, R.E.; Mutch, D.; Yamada, S.D.; Cohn, D.; Calvert, V.; Farley, J.; et al. Activity of sorafenib in recurrent ovarian cancer and primary peritoneal carcinomatosis: A gynecologic oncology group trial. J. Clin. Oncol. 2011, 29, 69-75. [CrossRef] [PubMed]
    • (2011) J. Clin. Oncol. , vol.29 , pp. 69-75
    • Matei, D.1    Sill, M.W.2    Lankes, H.A.3    DeGeest, K.4    Bristow, R.E.5    Mutch, D.6    Yamada, S.D.7    Cohn, D.8    Calvert, V.9    Farley, J.10
  • 83
    • 15044363940 scopus 로고    scopus 로고
    • Tamoxifen-resistant breast cancers show less frequent methylation of the estrogen receptor beta but not the estrogen receptor alpha gene
    • CrossRef, PubMed
    • Chang, H.G.; Kim, S.J.; Chung, K.-W.; Noh, D.-Y.; Kwon, Y.; Lee, E.S.; Kang, H.-S. Tamoxifen-resistant breast cancers show less frequent methylation of the estrogen receptor beta but not the estrogen receptor alpha gene. J. Mol. Med. 2005, 83, 132-139. [CrossRef] [PubMed]
    • (2005) J. Mol. Med. , vol.83 , pp. 132-139
    • Chang, H.G.1    Kim, S.J.2    Chung, K.-W.3    Noh, D.-Y.4    Kwon, Y.5    Lee, E.S.6    Kang, H.-S.7
  • 84
    • 33646128506 scopus 로고    scopus 로고
    • Epigenetics as a mechanism driving polygenic clinical drug resistance
    • CrossRef, PubMed
    • Glasspool, R.M.; Teodoridis, J.M.; Brown, R. Epigenetics as a mechanism driving polygenic clinical drug resistance. Br. J. Cancer 2006, 94, 1087-1092. [CrossRef] [PubMed]
    • (2006) Br. J. Cancer , vol.94 , pp. 1087-1092
    • Glasspool, R.M.1    Teodoridis, J.M.2    Brown, R.3
  • 85
    • 20444461499 scopus 로고    scopus 로고
    • Demethylation of the MCJ gene in stage III/IV epithelial ovarian cancer and response to chemotherapy
    • CrossRef, PubMed
    • Strathdee, G.; Vass, J.K.; Oien, K.A.; Siddiqui, N.; Curto-Garcia, J.; Brown, R. Demethylation of the MCJ gene in stage III/IV epithelial ovarian cancer and response to chemotherapy. Gynecol. Oncol. 2005, 97, 898-903. [CrossRef] [PubMed]
    • (2005) Gynecol. Oncol. , vol.97 , pp. 898-903
    • Strathdee, G.1    Vass, J.K.2    Oien, K.A.3    Siddiqui, N.4    Curto-Garcia, J.5    Brown, R.6
  • 86
    • 3042774430 scopus 로고    scopus 로고
    • The acquisition of hMLH1 methylation in plasma DNA after chemotherapy predicts poor survival for ovarian cancer patients
    • CrossRef, PubMed
    • Gifford, G.; Paul, J.; Vasey, P.A.; Kaye, S.B.; Brown, R. The acquisition of hMLH1 methylation in plasma DNA after chemotherapy predicts poor survival for ovarian cancer patients. Clin. Cancer Res. 2004, 10, 4420-4426. [CrossRef] [PubMed]
    • (2004) Clin. Cancer Res. , vol.10 , pp. 4420-4426
    • Gifford, G.1    Paul, J.2    Vasey, P.A.3    Kaye, S.B.4    Brown, R.5
  • 87
    • 73949106115 scopus 로고    scopus 로고
    • Epigenetic therapies for chemoresensitization of epithelial ovarian cancer
    • CrossRef, PubMed
    • Matei, D.E.; Nephew, K.P. Epigenetic therapies for chemoresensitization of epithelial ovarian cancer. Gynecol. Oncol. 2010, 116, 195-201. [CrossRef] [PubMed]
    • (2010) Gynecol. Oncol. , vol.116 , pp. 195-201
    • Matei, D.E.1    Nephew, K.P.2
  • 88
    • 84900344547 scopus 로고    scopus 로고
    • Inhibition of HDAC1 and DNMT1 modulate RGS10 expression and decrease ovarian cancer chemoresistance
    • CrossRef, PubMed
    • Cacan, E.; Ali, M.W.; Boyd, N.H.; Hooks, S.B.; Greer, S.F. Inhibition of HDAC1 and DNMT1 modulate RGS10 expression and decrease ovarian cancer chemoresistance. PLoS ONE 2014, 9, e87455. [CrossRef] [PubMed]
    • (2014) PLoS ONE , vol.9
    • Cacan, E.1    Ali, M.W.2    Boyd, N.H.3    Hooks, S.B.4    Greer, S.F.5
  • 90
    • 8544284078 scopus 로고    scopus 로고
    • The epigenetics of ovarian cancer drug resistance and resensitization
    • CrossRef, PubMed
    • Balch, C.; Huang, T.H.-M.; Brown, R.; Nephew, K.P. The epigenetics of ovarian cancer drug resistance and resensitization. Am. J. Obstet. Gynecol. 2004, 191, 1552-1572. [CrossRef] [PubMed]
    • (2004) Am. J. Obstet. Gynecol. , vol.191 , pp. 1552-1572
    • Balch, C.1    Huang, T.H.-M.2    Brown, R.3    Nephew, K.P.4
  • 92
    • 84865688852 scopus 로고    scopus 로고
    • Anticancer effects of histone deacetylase inhibitors and calpain inhibitor
    • Lapinska, K.; Housman, G.; Heerboth, S.; Longacre, M.; Sarkar, S. Anticancer effects of histone deacetylase inhibitors and calpain inhibitor. Anticancer Res. 2012, 32, 2523-2529.
    • (2012) Anticancer Res. , vol.32 , pp. 2523-2529
    • Lapinska, K.1    Housman, G.2    Heerboth, S.3    Longacre, M.4    Sarkar, S.5
  • 93
    • 10744223629 scopus 로고    scopus 로고
    • Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation
    • CrossRef
    • Fujji, S.; Luo, R.Z.; Yuan, J.; Kadota, M.; Oshimura, M.; Dent, S.R.; Kondo, Y.; Issa, J.J.; Bast, R.C.; Yu, Y. Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation. Hum. Mol. Genet. 2003, 12, 1791-1800. [CrossRef]
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1791-1800
    • Fujji, S.1    Luo, R.Z.2    Yuan, J.3    Kadota, M.4    Oshimura, M.5    Dent, S.R.6    Kondo, Y.7    Issa, J.J.8    Bast, R.C.9    Yu, Y.10
  • 96
    • 79951836778 scopus 로고    scopus 로고
    • T-oligos inhibit growth and induce apoptosis in human ovarian cancer cells
    • CrossRef, PubMed
    • Sarkar, S.; Faller, D.T. T-oligos inhibit growth and induce apoptosis in human ovarian cancer cells. Oligonucleotides 2011, 21, 47-53. [CrossRef] [PubMed]
    • (2011) Oligonucleotides , vol.21 , pp. 47-53
    • Sarkar, S.1    Faller, D.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.