-
1
-
-
54149095553
-
Biological principles of microRNA-mediated regulation: shared themes amid diversity
-
Flynt,A.S. et al. (2008) Biological principles of microRNA-mediated regulation: shared themes amid diversity. Nat. Rev. Genet., 9, 831-842.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 831-842
-
-
Flynt, A.S.1
-
2
-
-
39749110083
-
Small non-coding RNAs in animal development
-
Stefani,G. et al. (2008) Small non-coding RNAs in animal development. Nat. Rev. Mol. Cell Biol., 9, 219-230.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 219-230
-
-
Stefani, G.1
-
3
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin,G.A. et al. (2004) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl Acad. Sci. USA, 101, 2999-3004.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
-
4
-
-
33745168962
-
microRNAs exhibit high frequency genomic alterations in human cancer
-
Zhang,L. et al. (2006) microRNAs exhibit high frequency genomic alterations in human cancer. Proc. Natl Acad. Sci. USA, 103, 9136-9141.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 9136-9141
-
-
Zhang, L.1
-
5
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu,J. et al. (2005) MicroRNA expression profiles classify human cancers. Nature, 435, 834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
-
6
-
-
34548746977
-
MicroRNA signatures in human ovarian cancer
-
Iorio,M.V. et al. (2007) MicroRNA signatures in human ovarian cancer. Cancer Res., 67, 8699-8707.
-
(2007)
Cancer Res.
, vol.67
, pp. 8699-8707
-
-
Iorio, M.V.1
-
7
-
-
23844555119
-
MicroRNA gene expression deregulation in human breast cancer
-
Iorio,M.V. et al. (2005) MicroRNA gene expression deregulation in human breast cancer. Cancer Res., 65, 7065-7070.
-
(2005)
Cancer Res.
, vol.65
, pp. 7065-7070
-
-
Iorio, M.V.1
-
8
-
-
47149109822
-
MicroRNAs in normal and malignant hematopoiesis
-
Garzon,R. et al. (2008) MicroRNAs in normal and malignant hematopoiesis. Curr. Opin. Hematol., 15, 352-358.
-
(2008)
Curr. Opin. Hematol.
, vol.15
, pp. 352-358
-
-
Garzon, R.1
-
9
-
-
36248941518
-
MicroRNAs in carcinogenesis
-
Hagan,J.P. et al. (2007) MicroRNAs in carcinogenesis. Cytogenet. Genome Res., 118, 252-259.
-
(2007)
Cytogenet. Genome Res.
, vol.118
, pp. 252-259
-
-
Hagan, J.P.1
-
10
-
-
37549024511
-
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
-
Blenkiron,C. et al. (2007) MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol., 8, R214.
-
(2007)
Genome Biol.
, vol.8
-
-
Blenkiron, C.1
-
11
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia,S. et al. (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl Acad. Sci. USA, 103, 2257-2261.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
-
12
-
-
33847084602
-
Genome regulation by polycomb and trithorax proteins
-
Schuettengruber,B. et al. (2007) Genome regulation by polycomb and trithorax proteins. Cell, 128, 735-745.
-
(2007)
Cell
, vol.128
, pp. 735-745
-
-
Schuettengruber, B.1
-
13
-
-
0036830642
-
Role of histone H3 lysine 27 methylation in Polycombgroup silencing
-
Cao,R. et al. (2002) Role of histone H3 lysine 27 methylation in Polycombgroup silencing. Science, 298, 1039-1043.
-
(2002)
Science
, vol.298
, pp. 1039-1043
-
-
Cao, R.1
-
14
-
-
0034977239
-
The polycomb-group gene Ezh2 is required for early mouse development
-
O'Carroll,D. et al. (2001) The polycomb-group gene Ezh2 is required for early mouse development. Mol. Cell. Biol., 21, 4330-4336.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4330-4336
-
-
O'Carroll, D.1
-
15
-
-
7544230144
-
The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation
-
Caretti,G. et al. (2004) The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes Dev., 18, 2627-2638.
-
(2004)
Genes Dev.
, vol.18
, pp. 2627-2638
-
-
Caretti, G.1
-
16
-
-
44349086037
-
MicroRNA-26a targets the histone methyltransferase Enhancer of Zeste homolog 2 during myogenesis
-
Wong,C.F. et al. (2008) MicroRNA-26a targets the histone methyltransferase Enhancer of Zeste homolog 2 during myogenesis. J. Biol. Chem., 283, 9836-9843.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 9836-9843
-
-
Wong, C.F.1
-
17
-
-
62149122634
-
Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells
-
Ezhkova,E. et al. (2009) Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell, 136, 1122-1135.
-
(2009)
Cell
, vol.136
, pp. 1122-1135
-
-
Ezhkova, E.1
-
18
-
-
0035252592
-
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis
-
Muller,H. et al. (2001) E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. Genes Dev., 15, 267-285.
-
(2001)
Genes Dev.
, vol.15
, pp. 267-285
-
-
Muller, H.1
-
19
-
-
0142105414
-
EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
-
Bracken,A.P. et al. (2003) EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J., 22, 5323-5335.
-
(2003)
EMBO J.
, vol.22
, pp. 5323-5335
-
-
Bracken, A.P.1
-
20
-
-
18644382388
-
The polycomb group protein EZH2 is involved in progression of prostate cancer
-
Varambally,S. et al. (2002) The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature, 419, 624-629.
-
(2002)
Nature
, vol.419
, pp. 624-629
-
-
Varambally, S.1
-
21
-
-
33744519651
-
Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer
-
Matsukawa,Y. et al. (2006) Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer. Cancer Sci., 97, 484-491.
-
(2006)
Cancer Sci.
, vol.97
, pp. 484-491
-
-
Matsukawa, Y.1
-
22
-
-
33644822360
-
EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast
-
Bachmann,I.M. et al. (2006) EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. J. Clin. Oncol., 24, 268-273.
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 268-273
-
-
Bachmann, I.M.1
-
23
-
-
29344439946
-
Expression levels of the EZH2 polycomb transcriptional repressor correlate with aggressiveness and invasive potential of bladder carcinomas
-
Weikert,S. et al. (2005) Expression levels of the EZH2 polycomb transcriptional repressor correlate with aggressiveness and invasive potential of bladder carcinomas. Int. J. Mol. Med., 16, 349-353.
-
(2005)
Int. J. Mol. Med.
, vol.16
, pp. 349-353
-
-
Weikert, S.1
-
24
-
-
0141816752
-
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
-
Kleer,C.G. et al. (2003) EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc. Natl Acad. Sci. USA, 100, 11606-11611.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 11606-11611
-
-
Kleer, C.G.1
-
25
-
-
33750318686
-
Enhancer of Zeste 2 as a marker of preneoplastic progression in the breast
-
Ding,L. et al. (2006) Enhancer of Zeste 2 as a marker of preneoplastic progression in the breast. Cancer Res., 66, 9352-9355.
-
(2006)
Cancer Res.
, vol.66
, pp. 9352-9355
-
-
Ding, L.1
-
26
-
-
57649124289
-
Repression of E-cadherin by the polycomb group protein EZH2 in cancer
-
Cao,Q. et al. (2008) Repression of E-cadherin by the polycomb group protein EZH2 in cancer. Oncogene, 27, 7274-7284.
-
(2008)
Oncogene
, vol.27
, pp. 7274-7284
-
-
Cao, Q.1
-
27
-
-
65549083102
-
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2
-
Friedman,J.M. et al. (2009) The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. Cancer Res., 69, 2623-2629.
-
(2009)
Cancer Res.
, vol.69
, pp. 2623-2629
-
-
Friedman, J.M.1
-
28
-
-
58149239686
-
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
-
Varambally,S. et al. (2008) Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science, 322, 1695-1699.
-
(2008)
Science
, vol.322
, pp. 1695-1699
-
-
Varambally, S.1
-
29
-
-
70349764482
-
Mir-214-dependent regulation of the polycomb protein ezh2 in skeletal muscle and embryonic stem cells
-
Juan,A.H. et al. (2009) Mir-214-dependent regulation of the polycomb protein ezh2 in skeletal muscle and embryonic stem cells. Mol. Cell, 36, 61-74.
-
(2009)
Mol. Cell
, vol.36
, pp. 61-74
-
-
Juan, A.H.1
-
30
-
-
34250877841
-
A mammalian microRNA expression atlas based on small RNA library sequencing
-
Landgraf,P. et al. (2007) A mammalian microRNA expression atlas based on small RNA library sequencing. Cell, 129, 1401-1414.
-
(2007)
Cell
, vol.129
, pp. 1401-1414
-
-
Landgraf, P.1
-
31
-
-
24044534780
-
An optimized isolation and labeling platform for accurate microRNA expression profiling
-
Shingara,J. et al. (2005) An optimized isolation and labeling platform for accurate microRNA expression profiling. RNA, 11, 1461-1470.
-
(2005)
RNA
, vol.11
, pp. 1461-1470
-
-
Shingara, J.1
-
32
-
-
35748937338
-
Integrative genomics analysis reveals silencing of betaadrenergic signaling by polycomb in prostate cancer
-
Yu,J. et al. (2007) Integrative genomics analysis reveals silencing of betaadrenergic signaling by polycomb in prostate cancer. Cancer Cell, 12, 419-431.
-
(2007)
Cancer Cell
, vol.12
, pp. 419-431
-
-
Yu, J.1
-
33
-
-
61349112251
-
MYC stimulates EZH2 expression by repression of its negative regulator miR-26a
-
Sander,S. et al. (2008) MYC stimulates EZH2 expression by repression of its negative regulator miR-26a. Blood, 112, 4202-4212.
-
(2008)
Blood
, vol.112
, pp. 4202-4212
-
-
Sander, S.1
-
34
-
-
67649300721
-
Genes that mediate breast cancer metastasis to the brain
-
Bos,P.D. et al. (2009) Genes that mediate breast cancer metastasis to the brain. Nature, 459, 1005-1009.
-
(2009)
Nature
, vol.459
, pp. 1005-1009
-
-
Bos, P.D.1
-
35
-
-
29244469466
-
The epigenetic progenitor origin of human cancer
-
Feinberg,A.P. et al. (2006) The epigenetic progenitor origin of human cancer. Nat. Rev. Genet., 7, 21-33.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 21-33
-
-
Feinberg, A.P.1
|