-
1
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, Mao M, Peterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R and Friend SH. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002; 415(6871):530-536.
-
(2002)
Nature
, vol.415
, Issue.6871
, pp. 530-536
-
-
van't Veer, L.J.1
Dai, H.2
van de Vijver, M.J.3
He, Y.D.4
Hart, A.A.5
Mao, M.6
Peterse, H.L.7
van der Kooy, K.8
Marton, M.J.9
Witteveen, A.T.10
Schreiber, G.J.11
Kerkhoven, R.M.12
Roberts, C.13
Linsley, P.S.14
Bernards, R.15
Friend, S.H.16
-
2
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matese JC, Brown PO, Botstein D, Lonning PE, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad SciUSA. 2001; 98(19):10869-10874.
-
(2001)
Proc Natl Acad SciUSA
, vol.98
, Issue.19
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
Hastie, T.7
Eisen, M.B.8
van de Rijn, M.9
Jeffrey, S.S.10
Thorsen, T.11
Quist, H.12
Matese, J.C.13
Brown, P.O.14
Botstein, D.15
Lonning, P.E.16
-
3
-
-
81555216077
-
Gene expression profiling in breast cancer: classification, prognostication, and prediction
-
Reis-Filho JS and Pusztai L. Gene expression profiling in breast cancer: classification, prognostication, and prediction. Lancet. 2011; 378(9805):1812-1823.
-
(2011)
Lancet
, vol.378
, Issue.9805
, pp. 1812-1823
-
-
Reis-Filho, J.S.1
Pusztai, L.2
-
4
-
-
84866756366
-
The molecular profile of luminal B breast cancer
-
Creighton CJ. The molecular profile of luminal B breast cancer. Biologics: Targets & Therapy. 2012; 6:289-297.
-
(2012)
Biologics: Targets & Therapy
, vol.6
, pp. 289-297
-
-
Creighton, C.J.1
-
5
-
-
33744960226
-
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
-
Carey LA, Perou CM, Livasy CA, Dressler LG, Cowan D, Conway K, Karaca G, Troester MA, Tse CK, Edmiston S, Deming SL, Geradts J, Cheang MC, Nielsen TO, Moorman PG, Earp HS, et al. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA. 2006; 295(21):2492-2502.
-
(2006)
JAMA
, vol.295
, Issue.21
, pp. 2492-2502
-
-
Carey, L.A.1
Perou, C.M.2
Livasy, C.A.3
Dressler, L.G.4
Cowan, D.5
Conway, K.6
Karaca, G.7
Troester, M.A.8
Tse, C.K.9
Edmiston, S.10
Deming, S.L.11
Geradts, J.12
Cheang, M.C.13
Nielsen, T.O.14
Moorman, P.G.15
Earp, H.S.16
-
6
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Network TCGA. Comprehensive molecular portraits of human breast tumours. Nature. 2012; 490(7418):61-70.
-
(2012)
Nature
, vol.490
, Issue.7418
, pp. 61-70
-
-
Network, T.C.G.A.1
-
7
-
-
84859893371
-
Histone methylation: a dynamic mark in health, disease and inheritance
-
Greer EL and Shi Y. Histone methylation: a dynamic mark in health, disease and inheritance. Nat Rev Genet. 2012; 13(5):343-357.
-
(2012)
Nat Rev Genet
, vol.13
, Issue.5
, pp. 343-357
-
-
Greer, E.L.1
Shi, Y.2
-
8
-
-
77049099785
-
Histone methyltransferases in cancer
-
Albert M and Helin K. Histone methyltransferases in cancer. Semin Cell Developmental Biol. 2010; 21(2):209-220.
-
(2010)
Semin Cell Developmental Biol
, vol.21
, Issue.2
, pp. 209-220
-
-
Albert, M.1
Helin, K.2
-
9
-
-
84888132934
-
SET for life: biochemical activities and biological functions of SET domain-containing proteins
-
Herz HM, Garruss A and Shilatifard A. SET for life: biochemical activities and biological functions of SET domain-containing proteins. Trends Biochem Sci. 2013; 38(12):621-639.
-
(2013)
Trends Biochem Sci
, vol.38
, Issue.12
, pp. 621-639
-
-
Herz, H.M.1
Garruss, A.2
Shilatifard, A.3
-
10
-
-
84898547095
-
Driver mutations of cancer epigenomes
-
Roy DM, Walsh LA and Chan TA. Driver mutations of cancer epigenomes. Protein Cell. 2014; 5(4):265-296.
-
(2014)
Protein Cell
, vol.5
, Issue.4
, pp. 265-296
-
-
Roy, D.M.1
Walsh, L.A.2
Chan, T.A.3
-
11
-
-
84875745673
-
Interplay between the Cancer Genome and Epigenome
-
Shen H and Laird PW. Interplay between the Cancer Genome and Epigenome. Cell. 2013; 153(1):38-55.
-
(2013)
Cell
, vol.153
, Issue.1
, pp. 38-55
-
-
Shen, H.1
Laird, P.W.2
-
12
-
-
78449268847
-
Transforming properties of 8p11-12 amplified genes in human breast cancer
-
Yang ZQ, Liu G, Bollig-Fischer A, Giroux CN and Ethier SP. Transforming properties of 8p11-12 amplified genes in human breast cancer. Cancer Res. 2010; 70(21):8487-8497.
-
(2010)
Cancer Res
, vol.70
, Issue.21
, pp. 8487-8497
-
-
Yang, Z.Q.1
Liu, G.2
Bollig-Fischer, A.3
Giroux, C.N.4
Ethier, S.P.5
-
13
-
-
0141816752
-
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
-
Kleer CG, Cao Q, Varambally S, Shen R, Ota I, Tomlins SA, Ghosh D, Sewalt RG, Otte AP, Hayes DF, Sabel MS, Livant D, Weiss SJ, Rubin MA and Chinnaiyan AM. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc Natl Acad SciUSA. 2003; 100(20):11606-11611.
-
(2003)
Proc Natl Acad SciUSA
, vol.100
, Issue.20
, pp. 11606-11611
-
-
Kleer, C.G.1
Cao, Q.2
Varambally, S.3
Shen, R.4
Ota, I.5
Tomlins, S.A.6
Ghosh, D.7
Sewalt, R.G.8
Otte, A.P.9
Hayes, D.F.10
Sabel, M.S.11
Livant, D.12
Weiss, S.J.13
Rubin, M.A.14
Chinnaiyan, A.M.15
-
14
-
-
84884623771
-
EZH2 knockdown suppresses the growth and invasion of human inflammatory breast cancer cells
-
Mu Z, Li H, Fernandez SV, Alpaugh KR, Zhang R and Cristofanilli M. EZH2 knockdown suppresses the growth and invasion of human inflammatory breast cancer cells. J Exp Clin Cancer Res: CR. 2013; 32:70.
-
(2013)
J Exp Clin Cancer Res: CR
, vol.32
, pp. 70
-
-
Mu, Z.1
Li, H.2
Fernandez, S.V.3
Alpaugh, K.R.4
Zhang, R.5
Cristofanilli, M.6
-
15
-
-
84888090995
-
Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention
-
Tian X, Zhang S, Liu HM, Zhang YB, Blair CA, Mercola D, Sassone-Corsi P and Zi X. Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention. Curr Cancer Drug Targets. 2013; 13(5):558-579.
-
(2013)
Curr Cancer Drug Targets
, vol.13
, Issue.5
, pp. 558-579
-
-
Tian, X.1
Zhang, S.2
Liu, H.M.3
Zhang, Y.B.4
Blair, C.A.5
Mercola, D.6
Sassone-Corsi, P.7
Zi, X.8
-
16
-
-
33746255899
-
Gene amplification in cancer
-
Albertson DG. Gene amplification in cancer. Trends Genet. 2006; 22(8):447-455.
-
(2006)
Trends Genet
, vol.22
, Issue.8
, pp. 447-455
-
-
Albertson, D.G.1
-
18
-
-
84875740314
-
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
-
Gao JJ, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, Sun YC, Jacobsen A, Sinha R, Larsson E, Cerami E, Sander C and Schultz N. Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal. Sci Signaling. 2013; 6(269).
-
(2013)
Sci Signaling
, vol.6
, Issue.269
-
-
Gao, J.J.1
Aksoy, B.A.2
Dogrusoz, U.3
Dresdner, G.4
Gross, B.5
Sumer, S.O.6
Sun, Y.C.7
Jacobsen, A.8
Sinha, R.9
Larsson, E.10
Cerami, E.11
Sander, C.12
Schultz, N.13
-
19
-
-
84866002291
-
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data
-
Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA, Jacobsen A, Byrne CJ, Heuer ML, Larsson E, Antipin Y, Reva B, Goldberg AP, Sander C and Schultz N. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discovery. 2012; 2(5):401-404.
-
(2012)
Cancer Discovery
, vol.2
, Issue.5
, pp. 401-404
-
-
Cerami, E.1
Gao, J.2
Dogrusoz, U.3
Gross, B.E.4
Sumer, S.O.5
Aksoy, B.A.6
Jacobsen, A.7
Byrne, C.J.8
Heuer, M.L.9
Larsson, E.10
Antipin, Y.11
Reva, B.12
Goldberg, A.P.13
Sander, C.14
Schultz, N.15
-
20
-
-
84865066583
-
ChromoHub: a data hub for navigators of chromatin-mediated signalling
-
Liu L, Zhen XT, Denton E, Marsden BD and Schapira M. ChromoHub: a data hub for navigators of chromatin-mediated signalling. Bioinformatics. 2012; 28(16):2205-2206.
-
(2012)
Bioinformatics
, vol.28
, Issue.16
, pp. 2205-2206
-
-
Liu, L.1
Zhen, X.T.2
Denton, E.3
Marsden, B.D.4
Schapira, M.5
-
21
-
-
33846209170
-
Multiple interacting oncogenes on the 8p11-p12 amplicon in human breast cancer
-
Yang ZQ, Streicher KL, Ray ME, Abrams J and Ethier SP. Multiple interacting oncogenes on the 8p11-p12 amplicon in human breast cancer. Cancer Res. 2006; 66(24):11632-11643.
-
(2006)
Cancer Res
, vol.66
, Issue.24
, pp. 11632-11643
-
-
Yang, Z.Q.1
Streicher, K.L.2
Ray, M.E.3
Abrams, J.4
Ethier, S.P.5
-
22
-
-
77950308839
-
Breast cancer molecular profiling with single sample predictors: a retrospective analysis
-
Weigelt B, Mackay A, A'Hern R, Natrajan R, Tan DS, Dowsett M, Ashworth A and Reis-Filho JS. Breast cancer molecular profiling with single sample predictors: a retrospective analysis. The Lancet Oncology. 2010; 11(4):339-349.
-
(2010)
The Lancet Oncology
, vol.11
, Issue.4
, pp. 339-349
-
-
Weigelt, B.1
Mackay, A.2
A'Hern, R.3
Natrajan, R.4
Tan, D.S.5
Dowsett, M.6
Ashworth, A.7
Reis-Filho, J.S.8
-
23
-
-
84882452789
-
EZH2 promotes a bi-lineage identity in basal-like breast cancer cells
-
Granit RZ, Gabai Y, Hadar T, Karamansha Y, Liberman L, Waldhorn I, Gat-Viks I, Regev A, Maly B, Darash-Yahana M, Peretz T and Ben-Porath I. EZH2 promotes a bi-lineage identity in basal-like breast cancer cells. Oncogene. 2013; 32(33):3886-3895.
-
(2013)
Oncogene
, vol.32
, Issue.33
, pp. 3886-3895
-
-
Granit, R.Z.1
Gabai, Y.2
Hadar, T.3
Karamansha, Y.4
Liberman, L.5
Waldhorn, I.6
Gat-Viks, I.7
Regev, A.8
Maly, B.9
Darash-Yahana, M.10
Peretz, T.11
Ben-Porath, I.12
-
24
-
-
66649120472
-
A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4
-
Lee J, Kim DH, Lee S, Yang QH, Lee DK, Lee SK, Roeder RG and Lee JW. A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4. Proc Natl Acad SciUSA. 2009; 106(21):8513-8518.
-
(2009)
Proc Natl Acad SciUSA
, vol.106
, Issue.21
, pp. 8513-8518
-
-
Lee, J.1
Kim, D.H.2
Lee, S.3
Yang, Q.H.4
Lee, D.K.5
Lee, S.K.6
Roeder, R.G.7
Lee, J.W.8
-
25
-
-
65949110376
-
PIK3CA and PIK3CB Inhibition Produce Synthetic Lethality when Combined with Estrogen Deprivation in Estrogen Receptor-Positive Breast Cancer
-
Crowder RJ, Phommaly C, Tao Y, Hoog J, Luo JQ, Perou CM, Parker JS, Miller MA, Huntsman DG, Lin L, Snider J, Davies SR, Olson JA, Watson MA, Saporita A, Weber JD, et al. PIK3CA and PIK3CB Inhibition Produce Synthetic Lethality when Combined with Estrogen Deprivation in Estrogen Receptor-Positive Breast Cancer. Cancer Res. 2009; 69(9):3955-3962.
-
(2009)
Cancer Res
, vol.69
, Issue.9
, pp. 3955-3962
-
-
Crowder, R.J.1
Phommaly, C.2
Tao, Y.3
Hoog, J.4
Luo, J.Q.5
Perou, C.M.6
Parker, J.S.7
Miller, M.A.8
Huntsman, D.G.9
Lin, L.10
Snider, J.11
Davies, S.R.12
Olson, J.A.13
Watson, M.A.14
Saporita, A.15
Weber, J.D.16
-
26
-
-
84890284556
-
Molecular pathways: protein methyltransferases in cancer
-
Copeland RA. Molecular pathways: protein methyltransferases in cancer. Clin Cancer Res. 2013; 19(23):6344-6350.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.23
, pp. 6344-6350
-
-
Copeland, R.A.1
-
27
-
-
84886099830
-
Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer
-
Plass C, Pfister SM, Lindroth AM, Bogatyrova O, Claus R and Lichter P. Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer. Nat Rev Genet. 2013; 14(11):765-780.
-
(2013)
Nat Rev Genet
, vol.14
, Issue.11
, pp. 765-780
-
-
Plass, C.1
Pfister, S.M.2
Lindroth, A.M.3
Bogatyrova, O.4
Claus, R.5
Lichter, P.6
-
28
-
-
84877330098
-
Multifaceted role of EZH2 in breast and prostate tumorigenesis: epigenetics and beyond
-
Deb G, Thakur VS and Gupta S. Multifaceted role of EZH2 in breast and prostate tumorigenesis: epigenetics and beyond. Epigenetics. 2013; 8(5):464-476.
-
(2013)
Epigenetics
, vol.8
, Issue.5
, pp. 464-476
-
-
Deb, G.1
Thakur, V.S.2
Gupta, S.3
-
29
-
-
84866050864
-
Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes
-
Holm K, Grabau D, Lovgren K, Aradottir S, Gruvberger-Saal S, Howlin J, Saal LH, Ethier SP, Bendahl PO, Stal O, Malmstrom P, Ferno M, Ryden L, Hegardt C, Borg A and Ringner M. Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes. Molecular Oncol. 2012; 6(5):494-506.
-
(2012)
Molecular Oncol
, vol.6
, Issue.5
, pp. 494-506
-
-
Holm, K.1
Grabau, D.2
Lovgren, K.3
Aradottir, S.4
Gruvberger-Saal, S.5
Howlin, J.6
Saal, L.H.7
Ethier, S.P.8
Bendahl, P.O.9
Stal, O.10
Malmstrom, P.11
Ferno, M.12
Ryden, L.13
Hegardt, C.14
Borg, A.15
Ringner, M.16
-
30
-
-
79959272481
-
Cancers and the NSD family of histone lysine methyltransferases
-
Morishita M and di Luccio E. Cancers and the NSD family of histone lysine methyltransferases. Biochim Biophys Acta. 2011; 1816(2):158-163.
-
(2011)
Biochim Biophys Acta
, vol.1816
, Issue.2
, pp. 158-163
-
-
Morishita, M.1
di Luccio, E.2
-
31
-
-
22144433675
-
High-resolution genomic profiles of human lung cancer
-
Tonon G, Wong KK, Maulik G, Brennan C, Feng B, Zhang Y, Khatry DB, Protopopov A, You MJ, Aguirre AJ, Martin ES, Yang Z, Ji H, Chin L and Depinho RA. High-resolution genomic profiles of human lung cancer. Proc Natl Acad SciUSA. 2005; 102(27):9625-9630.
-
(2005)
Proc Natl Acad SciUSA
, vol.102
, Issue.27
, pp. 9625-9630
-
-
Tonon, G.1
Wong, K.K.2
Maulik, G.3
Brennan, C.4
Feng, B.5
Zhang, Y.6
Khatry, D.B.7
Protopopov, A.8
You, M.J.9
Aguirre, A.J.10
Martin, E.S.11
Yang, Z.12
Ji, H.13
Chin, L.14
Depinho, R.A.15
-
32
-
-
0037093259
-
NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15)
-
Rosati R, La Starza R, Veronese A, Aventin A, Schwienbacher C, Vallespi T, Negrini M, Martelli MF and Mecucci C. NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15). Blood. 2002; 99(10):3857-3860.
-
(2002)
Blood
, vol.99
, Issue.10
, pp. 3857-3860
-
-
Rosati, R.1
La Starza, R.2
Veronese, A.3
Aventin, A.4
Schwienbacher, C.5
Vallespi, T.6
Negrini, M.7
Martelli, M.F.8
Mecucci, C.9
-
33
-
-
59449094654
-
Molecular characterization of breast cancer with high-resolution oligonucleotide comparative genomic hybridization array
-
Andre F, Job B, Dessen P, Tordai A, Michiels S, Liedtke C, Richon C, Yan K, Wang B, Vassal G, Delaloge S, Hortobagyi GN, Symmans WF, Lazar V and Pusztai L. Molecular characterization of breast cancer with high-resolution oligonucleotide comparative genomic hybridization array. Clin Cancer Res. 2009; 15(2):441-451.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.2
, pp. 441-451
-
-
Andre, F.1
Job, B.2
Dessen, P.3
Tordai, A.4
Michiels, S.5
Liedtke, C.6
Richon, C.7
Yan, K.8
Wang, B.9
Vassal, G.10
Delaloge, S.11
Hortobagyi, G.N.12
Symmans, W.F.13
Lazar, V.14
Pusztai, L.15
-
34
-
-
33751032547
-
Genetic profiling of chromosome 1 in breast cancer: mapping of regions of gains and losses and identification of candidate genes on 1q
-
Orsetti B, Nugoli M, Cervera N, Lasorsa L, Chuchana P, Rouge C, Ursule L, Nguyen C, Bibeau F, Rodriguez C and Theillet C. Genetic profiling of chromosome 1 in breast cancer: mapping of regions of gains and losses and identification of candidate genes on 1q. Br J Cancer. 2006; 95(10):1439-1447.
-
(2006)
Br J Cancer
, vol.95
, Issue.10
, pp. 1439-1447
-
-
Orsetti, B.1
Nugoli, M.2
Cervera, N.3
Lasorsa, L.4
Chuchana, P.5
Rouge, C.6
Ursule, L.7
Nguyen, C.8
Bibeau, F.9
Rodriguez, C.10
Theillet, C.11
-
35
-
-
37549006702
-
Integrated profiling of basal and luminal breast cancers
-
Adelaide J, Finetti P, Bekhouche I, Repellini L, Geneix J, Sircoulomb F, Charafe-Jauffret E, Cervera N, Desplans J, Parzy D, Schoenmakers E, Viens P, Jacquemier J, Birnbaum D, Bertucci F and Chaffanet M. Integrated profiling of basal and luminal breast cancers. Cancer Res. 2007; 67(24):11565-11575.
-
(2007)
Cancer Res
, vol.67
, Issue.24
, pp. 11565-11575
-
-
Adelaide, J.1
Finetti, P.2
Bekhouche, I.3
Repellini, L.4
Geneix, J.5
Sircoulomb, F.6
Charafe-Jauffret, E.7
Cervera, N.8
Desplans, J.9
Parzy, D.10
Schoenmakers, E.11
Viens, P.12
Jacquemier, J.13
Birnbaum, D.14
Bertucci, F.15
Chaffanet, M.16
-
36
-
-
84901508481
-
Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis
-
Rodriguez-Paredes M, Martinez de Paz A, Simo-Riudalbas L, Sayols S, Moutinho C, Moran S, Villanueva A, Vazquez-Cedeira M, Lazo PA, Carneiro F, Moura CS, Vieira J, Teixeira MR and Esteller M. Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis. Oncogene. 2014; 33(21):2807-2813.
-
(2014)
Oncogene
, vol.33
, Issue.21
, pp. 2807-2813
-
-
Rodriguez-Paredes, M.1
Martinez de Paz, A.2
Simo-Riudalbas, L.3
Sayols, S.4
Moutinho, C.5
Moran, S.6
Villanueva, A.7
Vazquez-Cedeira, M.8
Lazo, P.A.9
Carneiro, F.10
Moura, C.S.11
Vieira, J.12
Teixeira, M.R.13
Esteller, M.14
-
37
-
-
84862027456
-
Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma
-
Lindgren D, Sjodahl G, Lauss M, Staaf J, Chebil G, Lovgren K, Gudjonsson S, Liedberg F, Patschan O, Mansson W, Ferno M and Hoglund M. Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma. PLoS One. 2012; 7(6):e38863.
-
(2012)
PLoS One
, vol.7
, Issue.6
-
-
Lindgren, D.1
Sjodahl, G.2
Lauss, M.3
Staaf, J.4
Chebil, G.5
Lovgren, K.6
Gudjonsson, S.7
Liedberg, F.8
Patschan, O.9
Mansson, W.10
Ferno, M.11
Hoglund, M.12
-
38
-
-
79953056443
-
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
-
Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferre F, Bourque C, Burke CJ, Turner L, Uong A, Johnson LA, Beroukhim R, et al. The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature. 2011; 471(7339):513-517.
-
(2011)
Nature
, vol.471
, Issue.7339
, pp. 513-517
-
-
Ceol, C.J.1
Houvras, Y.2
Jane-Valbuena, J.3
Bilodeau, S.4
Orlando, D.A.5
Battisti, V.6
Fritsch, L.7
Lin, W.M.8
Hollmann, T.J.9
Ferre, F.10
Bourque, C.11
Burke, C.J.12
Turner, L.13
Uong, A.14
Johnson, L.A.15
Beroukhim, R.16
-
39
-
-
33845204856
-
Repression of p53 activity by Smyd2-mediated methylation
-
Huang J, Perez-Burgos L, Placek BJ, Sengupta R, Richter M, Dorsey JA, Kubicek S, Opravil S, Jenuwein T and Berger SL. Repression of p53 activity by Smyd2-mediated methylation. Nature. 2006; 444(7119):629-632.
-
(2006)
Nature
, vol.444
, Issue.7119
, pp. 629-632
-
-
Huang, J.1
Perez-Burgos, L.2
Placek, B.J.3
Sengupta, R.4
Richter, M.5
Dorsey, J.A.6
Kubicek, S.7
Opravil, S.8
Jenuwein, T.9
Berger, S.L.10
-
40
-
-
78349236076
-
Methylation of the retinoblastoma tumor suppressor by SMYD2
-
Saddic LA, West LE, Aslanian A, Yates JR, 3rd, Rubin SM, Gozani O and Sage J. Methylation of the retinoblastoma tumor suppressor by SMYD2. J Biol Chem. 2010; 285(48):37733-37740.
-
(2010)
J Biol Chem
, vol.285
, Issue.48
, pp. 37733-37740
-
-
Saddic, L.A.1
West, L.E.2
Aslanian, A.3
Yates, J.R.4
Rubin, S.M.5
Gozani, O.6
Sage, J.7
-
41
-
-
84886380505
-
Regulation of estrogen receptor alpha by histone methyltransferase SMYD2-mediated protein methylation
-
Zhang X, Tanaka K, Yan J, Li J, Peng D, Jiang Y, Yang Z, Barton MC, Wen H and Shi X. Regulation of estrogen receptor alpha by histone methyltransferase SMYD2-mediated protein methylation. Proc Natl Acad SciUSA. 2013; 110(43):17284-17289.
-
(2013)
Proc Natl Acad SciUSA
, vol.110
, Issue.43
, pp. 17284-17289
-
-
Zhang, X.1
Tanaka, K.2
Yan, J.3
Li, J.4
Peng, D.5
Jiang, Y.6
Yang, Z.7
Barton, M.C.8
Wen, H.9
Shi, X.10
-
42
-
-
79960484704
-
Biochemical characterization of human SET and MYND domain-containing protein 2 methyltransferase
-
Wu J, Cheung T, Grande C, Ferguson AD, Zhu X, Theriault K, Code E, Birr C, Keen N and Chen H. Biochemical characterization of human SET and MYND domain-containing protein 2 methyltransferase. Biochemistry. 2011; 50(29):6488-6497.
-
(2011)
Biochemistry
, vol.50
, Issue.29
, pp. 6488-6497
-
-
Wu, J.1
Cheung, T.2
Grande, C.3
Ferguson, A.D.4
Zhu, X.5
Theriault, K.6
Code, E.7
Birr, C.8
Keen, N.9
Chen, H.10
-
43
-
-
67749114645
-
Requirement of histone methyltransferase SMYD3 for estrogen receptor-mediated transcription
-
Kim H, Heo K, Kim JH, Kim K, Choi J and An W. Requirement of histone methyltransferase SMYD3 for estrogen receptor-mediated transcription. J Biol Chem. 2009; 284(30):19867-19877.
-
(2009)
J Biol Chem
, vol.284
, Issue.30
, pp. 19867-19877
-
-
Kim, H.1
Heo, K.2
Kim, J.H.3
Kim, K.4
Choi, J.5
An, W.6
-
44
-
-
84902333080
-
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
-
Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, Sage J, et al. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature. 2014; 510(7504):283-287.
-
(2014)
Nature
, vol.510
, Issue.7504
, pp. 283-287
-
-
Mazur, P.K.1
Reynoird, N.2
Khatri, P.3
Jansen, P.W.4
Wilkinson, A.W.5
Liu, S.6
Barbash, O.7
Van Aller, G.S.8
Huddleston, M.9
Dhanak, D.10
Tummino, P.J.11
Kruger, R.G.12
Garcia, B.A.13
Butte, A.J.14
Vermeulen, M.15
Sage, J.16
-
45
-
-
36549086300
-
Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes
-
Gregory GD, Vakoc CR, Rozovskaia T, Zheng X, Patel S, Nakamura T, Canaani E and Blobel GA. Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes. Mol Cell Biol. 2007; 27(24):8466-8479.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.24
, pp. 8466-8479
-
-
Gregory, G.D.1
Vakoc, C.R.2
Rozovskaia, T.3
Zheng, X.4
Patel, S.5
Nakamura, T.6
Canaani, E.7
Blobel, G.A.8
-
46
-
-
84902520020
-
JARID1B is a luminal lineage-driving oncogene in breast cancer
-
Yamamoto S, Wu Z, Russnes HG, Takagi S, Peluffo G, Vaske C, Zhao X, Moen Vollan HK, Maruyama R, Ekram MB, Sun H, Kim JH, Carver K, Zucca M, Feng J, Almendro V, et al. JARID1B is a luminal lineage-driving oncogene in breast cancer. Cancer Cell. 2014; 25(6):762-777.
-
(2014)
Cancer Cell
, vol.25
, Issue.6
, pp. 762-777
-
-
Yamamoto, S.1
Wu, Z.2
Russnes, H.G.3
Takagi, S.4
Peluffo, G.5
Vaske, C.6
Zhao, X.7
Moen Vollan, H.K.8
Maruyama, R.9
Ekram, M.B.10
Sun, H.11
Kim, J.H.12
Carver, K.13
Zucca, M.14
Feng, J.15
Almendro, V.16
-
47
-
-
45149134029
-
Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes
-
Sun XJ, Xu PF, Zhou T, Hu M, Fu CT, Zhang Y, Jin Y, Chen Y, Chen SJ, Huang QH, Liu TX and Chen Z. Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes. PLoS One. 2008; 3(1):e1499.
-
(2008)
PLoS One
, vol.3
, Issue.1
-
-
Sun, X.J.1
Xu, P.F.2
Zhou, T.3
Hu, M.4
Fu, C.T.5
Zhang, Y.6
Jin, Y.7
Chen, Y.8
Chen, S.J.9
Huang, Q.H.10
Liu, T.X.11
Chen, Z.12
-
48
-
-
36348939746
-
Family expansion and gene rearrangements contributed to the functional specialization of PRDM genes in vertebrates
-
Fumasoni I, Meani N, Rambaldi D, Scafetta G, Alcalay M and Ciccarelli FD. Family expansion and gene rearrangements contributed to the functional specialization of PRDM genes in vertebrates. BMC Evolutionary Biol. 2007; 7:187.
-
(2007)
BMC Evolutionary Biol
, vol.7
, pp. 187
-
-
Fumasoni, I.1
Meani, N.2
Rambaldi, D.3
Scafetta, G.4
Alcalay, M.5
Ciccarelli, F.D.6
-
49
-
-
77953734190
-
CLLD8/KMT1F Is a Lysine Methyltransferase That Is Important for Chromosome Segregation
-
Falandry C, Fourel G, Galy V, Ristriani T, Horard B, Bensimon E, Salles G, Gilson E and Magdinier F. CLLD8/KMT1F Is a Lysine Methyltransferase That Is Important for Chromosome Segregation. J Biol Chem. 2010; 285(26):20234-20241.
-
(2010)
J Biol Chem
, vol.285
, Issue.26
, pp. 20234-20241
-
-
Falandry, C.1
Fourel, G.2
Galy, V.3
Ristriani, T.4
Horard, B.5
Bensimon, E.6
Salles, G.7
Gilson, E.8
Magdinier, F.9
-
50
-
-
33845666681
-
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
-
Botuyan MV, Lee J, Ward IM, Kim JE, Thompson JR, Chen J and Mer G. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell. 2006; 127(7):1361-1373.
-
(2006)
Cell
, vol.127
, Issue.7
, pp. 1361-1373
-
-
Botuyan, M.V.1
Lee, J.2
Ward, I.M.3
Kim, J.E.4
Thompson, J.R.5
Chen, J.6
Mer, G.7
-
51
-
-
33646438365
-
Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
-
Huang Y, Fang J, Bedford MT, Zhang Y and Xu RM. Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A. Science. 2006; 312(5774):748-751.
-
(2006)
Science
, vol.312
, Issue.5774
, pp. 748-751
-
-
Huang, Y.1
Fang, J.2
Bedford, M.T.3
Zhang, Y.4
Xu, R.M.5
-
52
-
-
37849015924
-
Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor
-
Lee J, Thompson JR, Botuyan MV and Mer G. Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nat Struct Mol Biol. 2008; 15(1):109-111.
-
(2008)
Nat Struct Mol Biol
, vol.15
, Issue.1
, pp. 109-111
-
-
Lee, J.1
Thompson, J.R.2
Botuyan, M.V.3
Mer, G.4
-
53
-
-
84866892833
-
Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis
-
Ballabio E and Milne TA. Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis. Cancers (Basel). 2012; 4(3):904-944.
-
(2012)
Cancers (Basel)
, vol.4
, Issue.3
, pp. 904-944
-
-
Ballabio, E.1
Milne, T.A.2
-
54
-
-
84891711796
-
The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers
-
Hu DQ, Gao X, Morgan MA, Herz HM, Smith ER and Shilatifard A. The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers. Mol Cell Biol. 2013; 33(23):4745-4754.
-
(2013)
Mol Cell Biol
, vol.33
, Issue.23
, pp. 4745-4754
-
-
Hu, D.Q.1
Gao, X.2
Morgan, M.A.3
Herz, H.M.4
Smith, E.R.5
Shilatifard, A.6
-
55
-
-
84896345293
-
Enhancer Malfunction in Cancer
-
Herz HM, Hu DQ and Shilatifard A. Enhancer Malfunction in Cancer. Mol Cell. 2014; 53(6):859-866.
-
(2014)
Mol Cell
, vol.53
, Issue.6
, pp. 859-866
-
-
Herz, H.M.1
Hu, D.Q.2
Shilatifard, A.3
-
56
-
-
66649120472
-
A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4
-
Lee J, Kim DH, Lee S, Yang QH, Lee DK, Lee SK, Roeder RG and Lee JW. A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4. Proc Natl Acad SciUSA. 2009; 106(21):8513-8518.
-
(2009)
Proc Natl Acad SciUSA
, vol.106
, Issue.21
, pp. 8513-8518
-
-
Lee, J.1
Kim, D.H.2
Lee, S.3
Yang, Q.H.4
Lee, D.K.5
Lee, S.K.6
Roeder, R.G.7
Lee, J.W.8
-
57
-
-
84874789539
-
Targeting genetic alterations in protein methyltransferases for personalized cancer therapeutics
-
Copeland RA, Moyer MP and Richon VM. Targeting genetic alterations in protein methyltransferases for personalized cancer therapeutics. Oncogene. 2013; 32(8):939-946.
-
(2013)
Oncogene
, vol.32
, Issue.8
, pp. 939-946
-
-
Copeland, R.A.1
Moyer, M.P.2
Richon, V.M.3
-
58
-
-
0032760412
-
Molecular cytogenetic analysis of 11 new breast cancer cell lines
-
Forozan F, Veldman R, Ammerman CA, Parsa NZ, Kallioniemi A, Kallioniemi OP and Ethier SP. Molecular cytogenetic analysis of 11 new breast cancer cell lines. Br J Cancer. 1999; 81(8):1328-1334.
-
(1999)
Br J Cancer
, vol.81
, Issue.8
, pp. 1328-1334
-
-
Forozan, F.1
Veldman, R.2
Ammerman, C.A.3
Parsa, N.Z.4
Kallioniemi, A.5
Kallioniemi, O.P.6
Ethier, S.P.7
|