-
1
-
-
67650874081
-
Cancer Statistics, 2009
-
Jemal A, Siegel R, Ward E, et al: Cancer Statistics, 2009. CA Cancer J Clin 59:225-249, 2009
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
2
-
-
0000065513
-
Ovarian cancer, fallopian tube carcinoma and peritoneal carcinoma
-
DeVita VT (ed): Philadelphia, PA, Lippincott-Raven
-
Ozols R: Ovarian cancer, fallopian tube carcinoma and peritoneal carcinoma, in DeVita VT (ed): Cancer, Principles and Practice of Oncology Philadelphia, PA, Lippincott-Raven, 1997, pp 1502-1540
-
(1997)
Cancer, Principles and Practice of Oncology
, pp. 1502-1540
-
-
Ozols, R.1
-
3
-
-
0035879099
-
Recurrent epithelial ovarian carcinoma: A randomized phase III study of pegylated liposomal doxorubicin versus topotecan
-
Gordon AN, Fleagle JT, Guthrie D, et al: Recurrent epithelial ovarian carcinoma: A randomized phase III study of pegylated liposomal doxorubicin versus topotecan. J Clin Oncol 19:3312-3322, 2001 (Pubitemid 32642183)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.14
, pp. 3312-3322
-
-
Gordon, A.N.1
Fleagle, J.T.2
Guthrie, D.3
Parkin, D.E.4
Gore, M.E.5
Lacave, A.J.6
-
4
-
-
0037440042
-
Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: A phase II trial of the Gynecologic Oncology Group
-
DOI 10.1200/JCO.2003.10.104
-
Bookman MA, Darcy KM, Clarke-Pearson D, et al: Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: A phase II trial of the Gynecologic Oncology Group. J Clin Oncol 21:283-290, 2003 (Pubitemid 46606157)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.2
, pp. 283-290
-
-
Bookman, M.A.1
Darcy, K.M.2
Clarke-Pearson, D.3
Boothby, R.A.4
Horowitz, I.R.5
-
5
-
-
0025786997
-
Trisomy 12 and K-ras-2 amplification in human ovarian tumors
-
Yang-Feng TL, Li SB, Leung WY, et al: Trisomy 12 and K-ras-2 amplification in human ovarian tumors. Int J Cancer 48:678-681, 1991
-
(1991)
Int J Cancer
, vol.48
, pp. 678-681
-
-
Yang-Feng, T.L.1
Li, S.B.2
Leung, W.Y.3
-
7
-
-
0027413895
-
Mutation of K-ras protooncogene in human ovarian epithelial tumors of borderline malignancy
-
Mok SC, Bell DA, Knapp RC, et al: Mutation of K-ras protooncogene in human ovarian epithelial tumors of borderline malignancy. Cancer Res 53:1489-1492, 1993 (Pubitemid 23113216)
-
(1993)
Cancer Research
, vol.53
, Issue.7
, pp. 1489-1492
-
-
Mok, S.C.-H.1
Bell, D.A.2
Knapp, R.C.3
Fishbaugh, P.M.4
Welch, W.R.5
Muto, M.G.6
Berkowitz, R.S.7
Tsao, S.-W.8
-
8
-
-
0032879120
-
Ras gene activation in malignant cells of human ovarian carcinoma peritoneal fluids
-
DOI 10.1023/A:1006611220434
-
Dokianakis DN, Varras MN, Papaefthimiou M, et al: Ras gene activation in malignant cells of human ovarian carcinoma peritoneal fluids. Clin Exp Metastasis 17:293-297, 1999 (Pubitemid 29477574)
-
(1999)
Clinical and Experimental Metastasis
, vol.17
, Issue.4
, pp. 293-297
-
-
Dokianakis, D.N.1
Varras, M.N.2
Papaefthimiou, M.3
Apostolopoulou, J.4
Simiakaki, H.5
Diakomanolis, E.6
Spandidos, D.A.7
-
9
-
-
0027422452
-
Point mutation of the ras oncogene in human ovarian cancer
-
Chien CH, Chow SN: Point mutation of the ras oncogene in human ovarian cancer. DNA Cell Biol 12:623-627, 1993
-
(1993)
DNA Cell Biol
, vol.12
, pp. 623-627
-
-
Chien, C.H.1
Chow, S.N.2
-
10
-
-
0042624835
-
Role of KRAS and BRAF gene mutations in mucinous ovarian carcinoma
-
DOI 10.1016/S0090-8258(03)00264-6
-
Gemignani ML, Schlaerth AC, Bogomolniy F, et al: Role of KRAS and BRAF gene mutations in mucinous ovarian carcinoma. Gynecol Oncol 90:378-381, 2003 (Pubitemid 36952030)
-
(2003)
Gynecologic Oncology
, vol.90
, Issue.2
, pp. 378-381
-
-
Gemignani, M.L.1
Schlaerth, A.C.2
Bogomolniy, F.3
Barakat, R.R.4
Lin, O.5
Soslow, R.6
Venkatraman, E.7
Boyd, J.8
-
11
-
-
41349100528
-
Pathogenesis of ovarian cancer: Lessons from morphology and molecular biology and their clinical implications
-
DOI 10.1097/PGP.0b013e318161e4f5
-
Kurman RJ, Shih IeM: Pathogenesis of ovarian cancer: Lessons from morphology and molecular biology and their clinical implications. Int J Gynecol Pathol 27:151-160, 2008 (Pubitemid 351450677)
-
(2008)
International Journal of Gynecological Pathology
, vol.27
, Issue.2
, pp. 151-160
-
-
Kurman, R.J.1
Shih, I.-M.2
-
12
-
-
13244256870
-
Origins and molecular pathology of ovarian cancer
-
suppl 2
-
Bell DA: Origins and molecular pathology of ovarian cancer. Mod Pathol 18:S19-S32, 2005 (suppl 2)
-
(2005)
Mod Pathol
, vol.18
-
-
Bell, D.A.1
-
13
-
-
0032520776
-
K-ras mutations in nonmucinous ovarian epithelial tumors: A molecular analysis and clinicopathologic study of 144 patients
-
DOI 10.1002/(SICI)1097-0142(19980315)82:6<1088::AID-CNCR12>3.0. CO;2-2
-
Cuatrecasas M, Erill N, Musulen E, et al: K-ras mutations in nonmucinous ovarian epithelial tumors: A molecular analysis and clinicopathologic study of 144 patients. Cancer 82:1088-1095, 1998 (Pubitemid 28136522)
-
(1998)
Cancer
, vol.82
, Issue.6
, pp. 1088-1095
-
-
Cuatrecasas, M.1
Erill, N.2
Musulen, E.3
Costa, I.4
Matias-Guiu, X.5
Prat, J.6
-
14
-
-
0030964881
-
K-ras mutations in mucinous ovarian tumors: A clinicopathologic and molecular study of 95 cases
-
DOI 10.1002/(SICI)1097-0142(19970415)79:8<1581::AID-CNCR21>3.0. CO;2-T
-
Cuatrecasas M, Villanueva A, Matias-Guiu X, et al: K-ras mutations in mucinous ovarian tumors: A clinicopathologic and molecular study of 95 cases. Cancer 79:1581-1586, 1997 (Pubitemid 27154791)
-
(1997)
Cancer
, vol.79
, Issue.8
, pp. 1581-1586
-
-
Cuatrecasas, M.1
Villanueva, A.2
Matias-Guiu, X.3
Prat, J.4
-
15
-
-
0037454224
-
Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma
-
Singer G, Oldt R 3rd, Cohen Y, et al: Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma. J Natl Cancer Inst 95:484-486, 2003 (Pubitemid 36432423)
-
(2003)
Journal of the National Cancer Institute
, vol.95
, Issue.6
, pp. 484-486
-
-
Singer, G.1
Oldt III, R.2
Cohen, Y.3
Wang, B.G.4
Sidransky, D.5
Kurman, R.J.6
Shih, I.-M.7
-
16
-
-
0035977185
-
Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer
-
DOI 10.1054/bjoc.2001.2139
-
McPhillips F, Mullen P, Monia BP, et al: Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer. Br J Cancer 85:1753-1758, 2001 (Pubitemid 34081523)
-
(2001)
British Journal of Cancer
, vol.85
, Issue.11
, pp. 1753-1758
-
-
McPhillips, F.1
Mullen, P.2
Monia, B.P.3
Ritchie, A.A.4
Dorr, F.A.5
Smyth, J.F.6
Langdon, S.P.7
-
17
-
-
1642296647
-
Antisense Oligonucleotide Targeting of Raf-1: Importance of Raf-1 mRNA Expression Levels and Raf-1-Dependent Signaling in Determining Growth Response in Ovarian Cancer
-
DOI 10.1158/1078-0432.CCR-03-0154
-
Mullen P, McPhillips F, MacLeod K, et al: Antisense oligonucleotide targeting of Raf-1: importance of raf-1 mRNA expression levels and raf-1-dependent signaling in determining growth response in ovarian cancer. Clin Cancer Res 10:2100-2108, 2004 (Pubitemid 38375572)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.6
, pp. 2100-2108
-
-
Mullen, P.1
McPhillips, F.2
MacLeod, K.3
Monia, B.4
Smyth, J.F.5
Langdon, S.P.6
-
18
-
-
33644540478
-
Comparison of strategies targeting Raf-1 mRNA in ovarian cancer
-
Mullen P, McPhillips F, Monia BP, et al: Comparison of strategies targeting Raf-1 mRNA in ovarian cancer. Int J Cancer 118:1565-1571, 2006
-
(2006)
Int J Cancer
, vol.118
, pp. 1565-1571
-
-
Mullen, P.1
McPhillips, F.2
Monia, B.P.3
-
19
-
-
33645506349
-
Autocrine activation of PDGFRalpha promotes the progression of ovarian cancer
-
Matei D, Emerson RE, Lai YC, et al: Autocrine activation of PDGFRalpha promotes the progression of ovarian cancer. Oncogene 25:2060-2069, 2006
-
(2006)
Oncogene
, vol.25
, pp. 2060-2069
-
-
Matei, D.1
Emerson, R.E.2
Lai, Y.C.3
-
20
-
-
0041570242
-
Expression of c-ABL, c-KIT, and platelet-derived growth factor receptor-beta in ovarian serous carcinoma and normal ovarian surface epithelium
-
DOI 10.1002/cncr.11561
-
Schmandt RE, Broaddus R, Lu KH, et al: Expression of c-ABL, c-KIT, and platelet-derived growth factor receptor-beta in ovarian serous carcinoma and normal ovarian surface epithelium. Cancer 98:758-764, 2003 (Pubitemid 36959272)
-
(2003)
Cancer
, vol.98
, Issue.4
, pp. 758-764
-
-
Schmandt, R.E.1
Broaddus, R.2
Lu, K.H.3
Shvartsman, H.4
Thornton, A.5
Malpica, A.6
Sun, C.7
Bodurka, D.C.8
Gershenson, D.M.9
-
21
-
-
0028904030
-
Expression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma
-
Boocock CA, Charnock-Jones DS, Sharkey AM, et al: Expression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma. J Natl Cancer Inst 87:506-516, 1995
-
(1995)
J Natl Cancer Inst
, vol.87
, pp. 506-516
-
-
Boocock, C.A.1
Charnock-Jones, D.S.2
Sharkey, A.M.3
-
22
-
-
1442290142
-
Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms
-
Erber R, Thurnher A, Katsen AD, et al: Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms. Faseb J 18:338-340, 2004
-
(2004)
Faseb J
, vol.18
, pp. 338-340
-
-
Erber, R.1
Thurnher, A.2
Katsen, A.D.3
-
23
-
-
33846212284
-
Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
-
DOI 10.1158/0008-5472.CAN-06-1377
-
Liu L, Cao Y, Chen C, et al: Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. Cancer Res 66:11851-11858, 2006 (Pubitemid 46094197)
-
(2006)
Cancer Research
, vol.66
, Issue.24
, pp. 11851-11858
-
-
Liu, L.1
Cao, Y.2
Chen, C.3
Zhang, X.4
McNabola, A.5
Wilkie, D.6
Wilhelm, S.7
Lynch, M.8
Carter, C.9
-
24
-
-
34250704834
-
Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice
-
DOI 10.1158/1535-7163.MCT-06-0595
-
Kim S, Yazici YD, Calzada G, et al: Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice. Mol Cancer Ther 6:1785-1792, 2007 (Pubitemid 46954055)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.6
, pp. 1785-1792
-
-
Kim, S.1
Yazici, Y.D.2
Calzada, G.3
Wang, Z.-Y.4
Younes, M.N.5
Jasser, S.A.6
El-Naggar, A.K.7
Myers, J.N.8
-
25
-
-
34147161209
-
Inhibition of tumor endothelial ERK activation, angiogenesis, and tumor growth by sorafenib (BAY45-9006)
-
Murphy DA, Makonnen S, Lassoued W, et al: Inhibition of tumor endothelial ERK activation, angiogenesis, and tumor growth by sorafenib (BAY45-9006). Am J Pathol 169:1875-1885, 2006
-
(2006)
Am J Pathol
, vol.169
, pp. 1875-1885
-
-
Murphy, D.A.1
Makonnen, S.2
Lassoued, W.3
-
26
-
-
0035848705
-
Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front
-
Paweletz CP, Charboneau L, Bichsel VE, et al: Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front. Oncogene 20:1981-1989, 2001
-
(2001)
Oncogene
, vol.20
, pp. 1981-1989
-
-
Paweletz, C.P.1
Charboneau, L.2
Bichsel, V.E.3
-
27
-
-
20644464974
-
Mapping molecular networks using proteomics: A vision for patient-tailored combination therapy
-
Petricoin EF 3rd, Bichsel VE, Calvert VS, et al: Mapping molecular networks using proteomics: A vision for patient-tailored combination therapy. J Clin Oncol 23:3614-3621, 2005
-
(2005)
J Clin Oncol
, vol.23
, pp. 3614-3621
-
-
Petricoin III, E.F.1
Bichsel, V.E.2
Calvert, V.S.3
-
28
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
-
Therasse P, Arbuck SG, Eisenhauer EA, et al: New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92:205-216, 2000
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 205-216
-
-
Therasse, P.1
Arbuck, S.G.2
Eisenhauer, E.A.3
-
29
-
-
36549090007
-
Enhanced B-Raf protein expression is independent of V600E mutant status in thyroid carcinomas
-
Kondo T, Nakazawa T, Murata S, et al: Enhanced B-Raf protein expression is independent of V600E mutant status in thyroid carcinomas. Hum Pathol 38:1810-1818, 2007
-
(2007)
Hum Pathol
, vol.38
, pp. 1810-1818
-
-
Kondo, T.1
Nakazawa, T.2
Murata, S.3
-
30
-
-
23044511620
-
Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: A Gynecologic Oncology Group Study
-
DOI 10.1158/1078-0432.CCR-05-0462
-
Schilder RJ, Sill MW, Chen X, et al: Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: A Gynecologic Oncology Group Study. Clin Cancer Res 11:5539-5548, 2005 (Pubitemid 41060831)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.15
, pp. 5539-5548
-
-
Schilder, R.J.1
Sill, M.W.2
Chen, X.3
Darcy, K.M.4
Decesare, S.L.5
Lewandowski, G.6
Lee, R.B.7
Arciero, C.A.8
Wu, H.9
Godwin, A.K.10
-
31
-
-
0032582620
-
Optimal flexible designs in phase II clinical trials
-
DOI 10.1002/(SICI)1097-0258(19981030)17:20<2301::AID-SIM927>3.0. CO;2-X
-
Chen TT, Ng TH: Optimal flexible designs in phase II clinical trials. Stat Med 17:2301-2312, 1998 (Pubitemid 28482675)
-
(1998)
Statistics in Medicine
, vol.17
, Issue.20
, pp. 2301-2312
-
-
Chen, T.T.1
Ng, T.-H.2
-
32
-
-
0000336139
-
Regression models and life tables
-
Cox D: Regression models and life tables. J Royal Stat Soc B 34:187-220, 1972
-
(1972)
J Royal Stat Soc B
, vol.34
, pp. 187-220
-
-
Cox, D.1
-
34
-
-
0030464206
-
On the relationship between response to treatment and survival time
-
DOI 10.1002/(SICI)1097-0258(19961230)15:24<2797::AID-SIM290>3.0. CO;2-V
-
Buyse M, Piedbois P: On the relationship between response to treatment and survival time. Stat Med 15:2797-2812, 1996 (Pubitemid 27011058)
-
(1996)
Statistics in Medicine
, vol.15
, Issue.24
, pp. 2797-2812
-
-
Buyse, M.1
Piedbois, P.2
-
35
-
-
33744984843
-
Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.03.6723
-
Ratain MJ, Eisen T, Stadler WM, et al: Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. J Clin Oncol 24:2505-2512, 2006 (Pubitemid 46630627)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.16
, pp. 2505-2512
-
-
Ratain, M.J.1
Eisen, T.2
Stadler, W.M.3
Flaherty, K.T.4
Kaye, S.B.5
Rosner, G.L.6
Gore, M.7
Desai, A.A.8
Patnaik, A.9
Xiong, H.Q.10
Rowinsky, E.11
Abbruzzese, J.L.12
Xia, C.13
Simantov, R.14
Schwartz, B.15
O'Dwyer, P.J.16
-
36
-
-
33749017926
-
Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
-
DOI 10.1200/JCO.2005.01.3441
-
Abou-Alfa GK, Schwartz L, Ricci S, et al: Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 24:4293-4300, 2006 (Pubitemid 46630787)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.26
, pp. 4293-4300
-
-
Abou-Alfa, G.K.1
Schwartz, L.2
Ricci, S.3
Amadori, D.4
Santoro, A.5
Figer, A.6
De, G.J.7
Douillard, J.-Y.8
Lathia, C.9
Schwartz, B.10
Taylor, I.11
Moscovici, M.12
Saltz, L.B.13
-
37
-
-
50649095250
-
Phase II trial of sorafenib in advanced thyroid cancer
-
Gupta-Abramson V, Troxel AB, Nellore A, et al: Phase II trial of sorafenib in advanced thyroid cancer. J Clin Oncol 26:4714-4719, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 4714-4719
-
-
Gupta-Abramson, V.1
Troxel, A.B.2
Nellore, A.3
-
38
-
-
34548504810
-
Phase II trial of sorafenib in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or nasopharyngeal carcinoma
-
DOI 10.1200/JCO.2006.10.2871
-
Elser C, Siu LL, Winquist E, et al: Phase II trial of sorafenib in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or nasopharyngeal carcinoma. J Clin Oncol 25:3766-3773, 2007 (Pubitemid 47372619)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.24
, pp. 3766-3773
-
-
Elser, C.1
Siu, L.L.2
Winquist, E.3
Agulnik, M.4
Pond, G.R.5
Chin, S.F.6
Francis, P.7
Cheiken, R.8
Elting, J.9
McNabola, A.10
Wilkie, D.11
Petrenciuc, O.12
Chen, E.X.13
-
39
-
-
68949094219
-
Keratocanthomas and squamous cell carcinomas in patients receiving sorafenib
-
Arnault JP, Wechsler J, Escudier B, et al: Keratocanthomas and squamous cell carcinomas in patients receiving sorafenib. J Clin Oncol 27:e59-61, 2009
-
(2009)
J Clin Oncol
, vol.27
-
-
Arnault, J.P.1
Wechsler, J.2
Escudier, B.3
-
40
-
-
65249127575
-
Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib
-
Dubauskas Z, Kunishige J, Prieto VG, et al: Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib. Clin Genitourin Cancer 7:20-23, 2009
-
(2009)
Clin Genitourin Cancer
, vol.7
, pp. 20-23
-
-
Dubauskas, Z.1
Kunishige, J.2
Prieto, V.G.3
-
41
-
-
45349101568
-
Multiple squamous cell carcinomas of the skin after therapy with sorafenib combined with tipifarnib
-
DOI 10.1001/archderm.144.6.779
-
Hong DS, Reddy SB, Prieto VG, et al: Multiple squamous cell carcinomas of the skin after therapy with sorafenib combined with tipifarnib. Arch Dermatol 144:779-782, 2008 (Pubitemid 351846880)
-
(2008)
Archives of Dermatology
, vol.144
, Issue.6
, pp. 779-782
-
-
Hong, D.S.1
Reddy, S.B.2
Prieto, V.G.3
Wright, J.J.4
Tannir, N.M.5
Cohen, P.R.6
Diwan, A.H.7
Evans, H.L.8
Kurzrock, R.9
-
42
-
-
70449123573
-
C-Raf inhibits MAPK activation and transformation by B-Raf(V600E)
-
Karreth FA, DeNicola GM, Winter SP, et al: C-Raf inhibits MAPK activation and transformation by B-Raf(V600E). Mol Cell 36:477-486, 2009
-
(2009)
Mol Cell
, vol.36
, pp. 477-486
-
-
Karreth, F.A.1
DeNicola, G.M.2
Winter, S.P.3
-
43
-
-
74849109743
-
Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF
-
Heidorn SJ, Milagre C, Whittaker S, et al: Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF. Cell 140:209-221, 2010
-
(2010)
Cell
, vol.140
, pp. 209-221
-
-
Heidorn, S.J.1
Milagre, C.2
Whittaker, S.3
-
44
-
-
77949346829
-
How blocking Raf activates the MAPK pathway
-
McCormick F: How blocking Raf activates the MAPK pathway. Pigment Cell Melanoma Res 23:187-189, 2010
-
(2010)
Pigment Cell Melanoma Res
, vol.23
, pp. 187-189
-
-
McCormick, F.1
-
45
-
-
34447502449
-
Experience with bevacizumab in the management of epithelial ovarian cancer
-
Burger RA: Experience with bevacizumab in the management of epithelial ovarian cancer. J Clin Oncol 25:2902-2908, 2007
-
(2007)
J Clin Oncol
, vol.25
, pp. 2902-2908
-
-
Burger, R.A.1
-
46
-
-
36849056497
-
Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer
-
DOI 10.1200/JCO.2007.12.0782
-
Cannistra SA, Matulonis UA, Penson RT, et al: Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer. J Clin Oncol 25:5180-5186, 2007 (Pubitemid 350232248)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.33
, pp. 5180-5186
-
-
Cannistra, S.A.1
Matulonis, U.A.2
Penson, R.T.3
Hambleton, J.4
Dupont, J.5
Mackey, H.6
Douglas, J.7
Burger, R.A.8
Armstrong, D.9
Wenham, R.10
McGuire, W.11
-
47
-
-
37849035249
-
Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: A trial of the California, Chicago, and Princess Margaret Hospital phase II consortia
-
Garcia AA, Hirte H, Fleming G, et al: Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: A trial of the California, Chicago, and Princess Margaret Hospital phase II consortia. J Clin Oncol 26:76-82, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 76-82
-
-
Garcia, A.A.1
Hirte, H.2
Fleming, G.3
-
48
-
-
34250168681
-
Phase I trial of sorafenib in combination with IFN alpha-2a in patients with unresectable and/or metastatic renal cell carcinoma or malignant melanoma
-
Escudier B, Lassau N, Angevin E, et al: Phase I trial of sorafenib in combination with IFN alpha-2a in patients with unresectable and/or metastatic renal cell carcinoma or malignant melanoma. Clin Cancer Res 13:1801-1809, 2007
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1801-1809
-
-
Escudier, B.1
Lassau, N.2
Angevin, E.3
-
49
-
-
33646468642
-
Pharmacodynamic monitoring of BAY 43-9006 (Sorafenib) in phase I clinical trials involving solid tumor and AML/MDS patients, using flow cytometry to monitor activation of the ERK pathway in peripheral blood cells
-
Tong FK, Chow S, Hedley D: Pharmacodynamic monitoring of BAY 43-9006 (Sorafenib) in phase I clinical trials involving solid tumor and AML/MDS patients, using flow cytometry to monitor activation of the ERK pathway in peripheral blood cells. Cytometry B Clin Cytom 70:107-114, 2006
-
(2006)
Cytometry B Clin Cytom
, vol.70
, pp. 107-114
-
-
Tong, F.K.1
Chow, S.2
Hedley, D.3
-
50
-
-
51049113834
-
BRAF V600E disrupts AZD6244-induced abrogation of negative feedback pathways between extracellular signal-regulated kinase and Raf proteins
-
Friday BB, Yu C, Dy GK, et al: BRAF V600E disrupts AZD6244-induced abrogation of negative feedback pathways between extracellular signal-regulated kinase and Raf proteins. Cancer Res 68:6145-6153, 2008
-
(2008)
Cancer Res
, vol.68
, pp. 6145-6153
-
-
Friday, B.B.1
Yu, C.2
Dy, G.K.3
-
51
-
-
19944430124
-
Regulation of Raf-1 by direct feedback phosphorylation
-
DOI 10.1016/j.molcel.2004.11.055, PII S1097276504008019
-
Dougherty MK, Müller J, Ritt DA, et al: Regulation of Raf-1 by direct feedback phosphorylation. Mol Cell 17:215-224, 2005 (Pubitemid 40138617)
-
(2005)
Molecular Cell
, vol.17
, Issue.2
, pp. 215-224
-
-
Dougherty, M.K.1
Muller, J.2
Ritt, D.A.3
Zhou, M.4
Zhou, X.Z.5
Copeland, T.D.6
Conrads, T.P.7
Veenstra, T.D.8
Lu, K.P.9
Morrison, D.K.10
-
52
-
-
45949109741
-
CA-125 response as a marker of clinical benefit in patients with recurrent ovarian cancer treated with gemcitabine and sorafenib: A trial of the PMH Phase II Consortium
-
suppl 18S; abstr 5519
-
Welch S, Hirte H, Elit L, et al: CA-125 response as a marker of clinical benefit in patients with recurrent ovarian cancer treated with gemcitabine and sorafenib: A trial of the PMH Phase II Consortium. J Clin Oncol 25:278s, 2007 (suppl 18S; abstr 5519)
-
(2007)
J Clin Oncol
, vol.25
-
-
Welch, S.1
Hirte, H.2
Elit, L.3
-
53
-
-
33846206208
-
Phase II study of sorafenib (BAY 43-9006) in combination with gemcitabine in recurrent epithelial ovarian cancer: A PMH phase II consortium trial
-
suppl 18S; abstr 5084
-
Welch S, Hirte H, Schilder RJ, et al: Phase II study of sorafenib (BAY 43-9006) in combination with gemcitabine in recurrent epithelial ovarian cancer: A PMH phase II consortium trial. J Clin Oncol 24:276s, 2006 (suppl 18S; abstr 5084)
-
(2006)
J Clin Oncol
, vol.24
-
-
Welch, S.1
Hirte, H.2
Schilder, R.J.3
|