메뉴 건너뛰기




Volumn 7, Issue 19, 2016, Pages 27527-27537

Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice

Author keywords

Centrosome; Cilium; Cylindromatosis; Histone deacetylase 6; Knockout mouse

Indexed keywords

ALPHA TUBULIN; DEUBIQUITINASE; DEUBIQUITINASE CYLINDROMATOSIS; HISTONE DEACETYLASE 6; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; CYLINDROMATOSIS PROTEIN, MOUSE; HDAC6 PROTEIN, MOUSE; SHH PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

EID: 84968918978     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.8374     Document Type: Article
Times cited : (8)

References (51)
  • 1
    • 84855460847 scopus 로고    scopus 로고
    • Cilia in vertebrate development and disease
    • Oh EC, Katsanis N. Cilia in vertebrate development and disease. Development. 2012; 139: 443-448.
    • (2012) Development. , vol.139 , pp. 443-448
    • Oh, E.C.1    Katsanis, N.2
  • 2
    • 84887135056 scopus 로고    scopus 로고
    • Expanding horizons: ciliary proteins reach beyond cilia
    • Yuan S, Sun Z. Expanding horizons: ciliary proteins reach beyond cilia. Annu Rev Genet. 2013; 47: 353-376.
    • (2013) Annu Rev Genet. , vol.47 , pp. 353-376
    • Yuan, S.1    Sun, Z.2
  • 3
    • 77954310807 scopus 로고    scopus 로고
    • Ubiquitin chain cleavage: CYLD at work
    • Massoumi R. Ubiquitin chain cleavage: CYLD at work. Trends Biochem Sci. 2010; 35: 392-399.
    • (2010) Trends Biochem Sci. , vol.35 , pp. 392-399
    • Massoumi, R.1
  • 4
    • 44049088740 scopus 로고    scopus 로고
    • The tumor suppressor CYLD regulates microtubule dynamics and plays a role in cell migration
    • Gao J, Huo L, Sun X, Liu M, Li D, Dong JT, Zhou J. The tumor suppressor CYLD regulates microtubule dynamics and plays a role in cell migration. J Biol Chem. 2008; 283: 8802-8809.
    • (2008) J Biol Chem. , vol.283 , pp. 8802-8809
    • Gao, J.1    Huo, L.2    Sun, X.3    Liu, M.4    Li, D.5    Dong, J.T.6    Zhou, J.7
  • 5
    • 77953284316 scopus 로고    scopus 로고
    • CYLD regulates angiogenesis by mediating vascular endothelial cell migration
    • Gao J, Sun L, Huo L, Liu M, Li D, Zhou J. CYLD regulates angiogenesis by mediating vascular endothelial cell migration. Blood. 2010; 115: 4130-4137.
    • (2010) Blood. , vol.115 , pp. 4130-4137
    • Gao, J.1    Sun, L.2    Huo, L.3    Liu, M.4    Li, D.5    Zhou, J.6
  • 6
    • 84897968714 scopus 로고    scopus 로고
    • CYLD coordinates with EB1 to regulate microtubule dynamics and cell migration
    • Li D, Gao J, Yang Y, Sun L, Suo S, Luo Y, Shui W, Zhou J, Liu M. CYLD coordinates with EB1 to regulate microtubule dynamics and cell migration. Cell Cycle. 2014; 13: 974-983.
    • (2014) Cell Cycle. , vol.13 , pp. 974-983
    • Li, D.1    Gao, J.2    Yang, Y.3    Sun, L.4    Suo, S.5    Luo, Y.6    Shui, W.7    Zhou, J.8    Liu, M.9
  • 8
    • 77955506844 scopus 로고    scopus 로고
    • Tumour suppressor CYLD is a negative regulator of the mitotic kinase Aurora-B
    • Sun L, Gao J, Huo L, Sun X, Shi X, Liu M, Li D, Zhang C, Zhou J. Tumour suppressor CYLD is a negative regulator of the mitotic kinase Aurora-B. J Pathol. 2010; 221: 425-432.
    • (2010) J Pathol. , vol.221 , pp. 425-432
    • Sun, L.1    Gao, J.2    Huo, L.3    Sun, X.4    Shi, X.5    Liu, M.6    Li, D.7    Zhang, C.8    Zhou, J.9
  • 9
    • 84893848639 scopus 로고    scopus 로고
    • CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation
    • Yang Y, Liu M, Li D, Ran J, Gao J, Suo S, Sun SC, Zhou J. CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation. Proc Natl Acad Sci U S A. 2014; 111: 2158-2163.
    • (2014) Proc Natl Acad Sci U S A. , vol.111 , pp. 2158-2163
    • Yang, Y.1    Liu, M.2    Li, D.3    Ran, J.4    Gao, J.5    Suo, S.6    Sun, S.C.7    Zhou, J.8
  • 10
    • 75649119696 scopus 로고    scopus 로고
    • CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin
    • Wickstrom SA, Masoumi KC, Khochbin S, Fassler R, Massoumi R. CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin. EMBO J. 2010; 29: 131-144.
    • (2010) EMBO J. , vol.29 , pp. 131-144
    • Wickstrom, S.A.1    Masoumi, K.C.2    Khochbin, S.3    Fassler, R.4    Massoumi, R.5
  • 12
    • 79952152655 scopus 로고    scopus 로고
    • CYLD: a deubiquitination enzyme with multiple roles in cancer
    • Massoumi R. CYLD: a deubiquitination enzyme with multiple roles in cancer. Future Oncol. 2011; 7: 285-297.
    • (2011) Future Oncol. , vol.7 , pp. 285-297
    • Massoumi, R.1
  • 15
    • 34250758641 scopus 로고    scopus 로고
    • HEF1-dependent Aurora A activation induces disassembly of the primary cilium
    • Pugacheva EN, Jablonski SA, Hartman TR, Henske EP, Golemis EA. HEF1-dependent Aurora A activation induces disassembly of the primary cilium. Cell. 2007; 129: 1351-1363.
    • (2007) Cell. , vol.129 , pp. 1351-1363
    • Pugacheva, E.N.1    Jablonski, S.A.2    Hartman, T.R.3    Henske, E.P.4    Golemis, E.A.5
  • 18
    • 84890033642 scopus 로고    scopus 로고
    • The nephronophthisis gene product NPHP2/Inversin interacts with Aurora A and interferes with HDAC6-mediated cilia disassembly
    • Mergen M, Engel C, Muller B, Follo M, Schafer T, Jung M, Walz G. The nephronophthisis gene product NPHP2/Inversin interacts with Aurora A and interferes with HDAC6-mediated cilia disassembly. Nephrol Dial Transplant. 2013; 28: 2744-2753.
    • (2013) Nephrol Dial Transplant. , vol.28 , pp. 2744-2753
    • Mergen, M.1    Engel, C.2    Muller, B.3    Follo, M.4    Schafer, T.5    Jung, M.6    Walz, G.7
  • 19
    • 84923376554 scopus 로고    scopus 로고
    • The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis
    • Kim M, Kim M, Lee MS, Kim CH, Lim DS. The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis. Nat Commun. 2014; 5: 5370.
    • (2014) Nat Commun. , vol.5 , pp. 5370
    • Kim, M.1    Kim, M.2    Lee, M.S.3    Kim, C.H.4    Lim, D.S.5
  • 20
    • 84924061350 scopus 로고    scopus 로고
    • beta-catenin links von hippel-lindau to aurora kinase A and loss of primary cilia in renal cell carcinoma
    • Dere R, Perkins AL, Bawa-Khalfe T, Jonasch D, Walker CL. beta-catenin links von hippel-lindau to aurora kinase A and loss of primary cilia in renal cell carcinoma. J Am Soc Nephrol. 2015; 26: 553-564.
    • (2015) J Am Soc Nephrol. , vol.26 , pp. 553-564
    • Dere, R.1    Perkins, A.L.2    Bawa-Khalfe, T.3    Jonasch, D.4    Walker, C.L.5
  • 21
    • 77953565925 scopus 로고    scopus 로고
    • The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis
    • Li Y, Wei Q, Zhang Y, Ling K, Hu J. The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis. J Cell Biol. 2010; 189: 1039-1051.
    • (2010) J Cell Biol. , vol.189 , pp. 1039-1051
    • Li, Y.1    Wei, Q.2    Zhang, Y.3    Ling, K.4    Hu, J.5
  • 23
    • 84877908359 scopus 로고    scopus 로고
    • PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry
    • Wang G, Chen Q, Zhang X, Zhang B, Zhuo X, Liu J, Jiang Q, Zhang C. PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry. J Cell Sci. 2013; 126: 1355-1365.
    • (2013) J Cell Sci. , vol.126 , pp. 1355-1365
    • Wang, G.1    Chen, Q.2    Zhang, X.3    Zhang, B.4    Zhuo, X.5    Liu, J.6    Jiang, Q.7    Zhang, C.8
  • 25
    • 84938866406 scopus 로고    scopus 로고
    • Deacetylation of alpha-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly
    • Ran J, Yang Y, Li D, Liu M, Zhou J. Deacetylation of alpha-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly. Sci Rep. 2015; 5: 12917.
    • (2015) Sci Rep. , vol.5 , pp. 12917
    • Ran, J.1    Yang, Y.2    Li, D.3    Liu, M.4    Zhou, J.5
  • 27
    • 84955188661 scopus 로고    scopus 로고
    • Ciliopathies: does HDAC6 represent a new therapeutic target?
    • Yu F, Ran J, Zhou J. Ciliopathies: does HDAC6 represent a new therapeutic target? Trends Pharmacol Sci. 2016; 37: 114-119.
    • (2016) Trends Pharmacol Sci. , vol.37 , pp. 114-119
    • Yu, F.1    Ran, J.2    Zhou, J.3
  • 28
    • 35548974703 scopus 로고    scopus 로고
    • Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD
    • Wright A, Reiley WW, Chang M, Jin W, Lee AJ, Zhang M, Sun SC. Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. Dev Cell. 2007; 13: 705-716.
    • (2007) Dev Cell. , vol.13 , pp. 705-716
    • Wright, A.1    Reiley, W.W.2    Chang, M.3    Jin, W.4    Lee, A.J.5    Zhang, M.6    Sun, S.C.7
  • 30
  • 31
    • 84879414522 scopus 로고    scopus 로고
    • The mechanisms of Hedgehog signalling and its roles in development and disease
    • Briscoe J, Therond PP. The mechanisms of Hedgehog signalling and its roles in development and disease. Nat Rev Mol Cell Biol. 2013; 14: 416-429.
    • (2013) Nat Rev Mol Cell Biol. , vol.14 , pp. 416-429
    • Briscoe, J.1    Therond, P.P.2
  • 37
    • 79953203531 scopus 로고    scopus 로고
    • Regulation of Tat acetylation and transactivation activity by the microtubule-associated deacetylase HDAC6
    • Huo L, Li D, Sun X, Shi X, Karna P, Yang W, Liu M, Qiao W, Aneja R, Zhou J. Regulation of Tat acetylation and transactivation activity by the microtubule-associated deacetylase HDAC6. J Biol Chem. 2011; 286: 9280-9286.
    • (2011) J Biol Chem. , vol.286 , pp. 9280-9286
    • Huo, L.1    Li, D.2    Sun, X.3    Shi, X.4    Karna, P.5    Yang, W.6    Liu, M.7    Qiao, W.8    Aneja, R.9    Zhou, J.10
  • 39
    • 84922080063 scopus 로고    scopus 로고
    • Proteomic identification and functional characterization of MYH9, Hsc70, and DNAJA1 as novel substrates of HDAC6 deacetylase activity
    • Zhang L, Liu S, Liu N, Zhang Y, Liu M, Li D, Seto E, Yao TP, Shui W, Zhou J. Proteomic identification and functional characterization of MYH9, Hsc70, and DNAJA1 as novel substrates of HDAC6 deacetylase activity. Protein Cell. 2015; 6: 42-54.
    • (2015) Protein Cell. , vol.6 , pp. 42-54
    • Zhang, L.1    Liu, S.2    Liu, N.3    Zhang, Y.4    Liu, M.5    Li, D.6    Seto, E.7    Yao, T.P.8    Shui, W.9    Zhou, J.10
  • 41
    • 79953219078 scopus 로고    scopus 로고
    • Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner
    • Li D, Xie S, Ren Y, Huo L, Gao J, Cui D, Liu M, Zhou J. Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner. Protein Cell. 2011; 2: 150-160.
    • (2011) Protein Cell. , vol.2 , pp. 150-160
    • Li, D.1    Xie, S.2    Ren, Y.3    Huo, L.4    Gao, J.5    Cui, D.6    Liu, M.7    Zhou, J.8
  • 42
    • 84947792534 scopus 로고    scopus 로고
    • New HDAC6-mediated deacetylation sites of tubulin in the mouse brain identified by quantitative mass spectrometry
    • Liu N, Xiong Y, Li S, Ren Y, He Q, Gao S, Zhou J, Shui W. New HDAC6-mediated deacetylation sites of tubulin in the mouse brain identified by quantitative mass spectrometry. Sci Rep. 2015; 5: 16869.
    • (2015) Sci Rep. , vol.5 , pp. 16869
    • Liu, N.1    Xiong, Y.2    Li, S.3    Ren, Y.4    He, Q.5    Gao, S.6    Zhou, J.7    Shui, W.8
  • 43
    • 84898599000 scopus 로고    scopus 로고
    • Histone deacetylase 6 and cytoplasmic linker protein 170 function together to regulate the motility of pancreatic cancer cells
    • Li D, Sun X, Zhang L, Yan B, Xie S, Liu R, Liu M, Zhou J. Histone deacetylase 6 and cytoplasmic linker protein 170 function together to regulate the motility of pancreatic cancer cells. Protein Cell. 2014; 5: 214-223.
    • (2014) Protein Cell. , vol.5 , pp. 214-223
    • Li, D.1    Sun, X.2    Zhang, L.3    Yan, B.4    Xie, S.5    Liu, R.6    Liu, M.7    Zhou, J.8
  • 48
    • 37549010715 scopus 로고    scopus 로고
    • Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis
    • Gao YS, Hubbert CC, Lu J, Lee YS, Lee JY, Yao TP. Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis. Mol Cell Biol. 2007; 27: 8637-8647.
    • (2007) Mol Cell Biol. , vol.27 , pp. 8637-8647
    • Gao, Y.S.1    Hubbert, C.C.2    Lu, J.3    Lee, Y.S.4    Lee, J.Y.5    Yao, T.P.6
  • 49
    • 80052990215 scopus 로고    scopus 로고
    • CEP70 protein interacts with gamma-tubulin to localize at the centrosome and is critical for mitotic spindle assembly
    • Shi X, Sun X, Liu M, Li D, Aneja R, Zhou J. CEP70 protein interacts with gamma-tubulin to localize at the centrosome and is critical for mitotic spindle assembly. J Biol Chem. 2011; 286: 33401-33408.
    • (2011) J Biol Chem. , vol.286 , pp. 33401-33408
    • Shi, X.1    Sun, X.2    Liu, M.3    Li, D.4    Aneja, R.5    Zhou, J.6
  • 50
    • 77952759760 scopus 로고    scopus 로고
    • Ectopic expression of the microtubuledependent motor protein Eg5 promotes pancreatic tumourigenesis
    • Liu M, Wang X, Yang Y, Li D, Ren H, Zhu Q, Chen Q, Han S, Hao J, Zhou J. Ectopic expression of the microtubuledependent motor protein Eg5 promotes pancreatic tumourigenesis. J Pathol. 2010; 221: 221-228.
    • (2010) J Pathol. , vol.221 , pp. 221-228
    • Liu, M.1    Wang, X.2    Yang, Y.3    Li, D.4    Ren, H.5    Zhu, Q.6    Chen, Q.7    Han, S.8    Hao, J.9    Zhou, J.10
  • 51
    • 84959010938 scopus 로고    scopus 로고
    • Cep70 overexpression stimulates pancreatic cancer by inducing centrosome abnormality and microtubule disorganization
    • Xie S, Qin J, Liu S, Zhang Y, Wang J, Shi X, Li D, Zhou J, Liu M. Cep70 overexpression stimulates pancreatic cancer by inducing centrosome abnormality and microtubule disorganization. Sci Rep. 2016; 6: 21263.
    • (2016) Sci Rep. , vol.6 , pp. 21263
    • Xie, S.1    Qin, J.2    Liu, S.3    Zhang, Y.4    Wang, J.5    Shi, X.6    Li, D.7    Zhou, J.8    Liu, M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.