HDAC6 is a target for protection and regeneration following injury in the nervous system

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 46, 2009, Pages 19599-19604

  Rivieccio, Mark A ^a,b   Brochier, Camille ^a,b   Willis, Dianna E ^c   Walker, Breset A ^b   D'Annibale, Melissa A ^a   McLaughlin, Kathryn ^a   Siddiq, Ambreena ^a,b   Kozikowski, Alan P ^d   Jaffrey, Samie R ^b   Twiss, Jeffery L ^c   Ratan, Rajiv R ^a,b   Langley, Brett ^a,b  

^a BURKE MEDICAL RESEARCH INSTITUTE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

HDAC inhibitor; Histone deacetylase; Neuroprotection

Indexed keywords

ALPHA TUBULIN; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE INHIBITOR; MYELIN ASSOCIATED GLYCOPROTEIN; PROTEOCHONDROITIN SULFATE; SMALL INTERFERING RNA; HDAC6 PROTEIN, RAT; HISTONE DEACETYLASE;

ACETYLATION; ANIMAL CELL; ARTICLE; CELL DEATH; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOPLASM; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; GLIA; MALE; NERVE CELL; NERVE DEGENERATION; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NERVE REGENERATION; NERVOUS SYSTEM INJURY; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; APOPTOSIS; BRAIN CORTEX; DEGENERATIVE DISEASE; ENZYMOLOGY; GENETICS; INJURY; METABOLISM; NEURITE; PHYSIOLOGY; RNA INTERFERENCE; SPINAL GANGLION; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; CENTRAL NERVOUS SYSTEM; CEREBRAL CORTEX; GANGLIA, SPINAL; HISTONE DEACETYLASES; MALE; NERVE REGENERATION; NEURITES; NEURODEGENERATIVE DISEASES; NEURONS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE;

EID: 73349143672     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0907935106     Document Type: Article

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