-
2
-
-
84928626421
-
SnapShot: sensing and signaling by cilia
-
K. Zimmerman, and B.K. Yoder SnapShot: sensing and signaling by cilia Cell 161 2015 692
-
(2015)
Cell
, vol.161
, pp. 692
-
-
Zimmerman, K.1
Yoder, B.K.2
-
3
-
-
84855460847
-
Cilia in vertebrate development and disease
-
E.C. Oh, and N. Katsanis Cilia in vertebrate development and disease Development 139 2012 443 448
-
(2012)
Development
, vol.139
, pp. 443-448
-
-
Oh, E.C.1
Katsanis, N.2
-
4
-
-
84923265004
-
Histone deacetylase 6 in health and disease
-
C. Seidel, and et al. Histone deacetylase 6 in health and disease Epigenomics 7 2015 103 118
-
(2015)
Epigenomics
, vol.7
, pp. 103-118
-
-
Seidel, C.1
-
5
-
-
0037161744
-
HDAC6 is a microtubule-associated deacetylase
-
C. Hubbert, and et al. HDAC6 is a microtubule-associated deacetylase Nature 417 2002 455 458
-
(2002)
Nature
, vol.417
, pp. 455-458
-
-
Hubbert, C.1
-
6
-
-
12244295468
-
In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation
-
A. Matsuyama, and et al. In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation EMBO J. 21 2002 6820 6831
-
(2002)
EMBO J.
, vol.21
, pp. 6820-6831
-
-
Matsuyama, A.1
-
7
-
-
34447315270
-
HDAC6 modulates cell motility by altering the acetylation level of cortactin
-
X. Zhang, and et al. HDAC6 modulates cell motility by altering the acetylation level of cortactin Mol. Cell 27 2007 197 213
-
(2007)
Mol. Cell
, vol.27
, pp. 197-213
-
-
Zhang, X.1
-
8
-
-
0037416151
-
HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo
-
Y. Zhang, and et al. HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo EMBO J. 22 2003 1168 1179
-
(2003)
EMBO J.
, vol.22
, pp. 1168-1179
-
-
Zhang, Y.1
-
9
-
-
79953219078
-
Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner
-
D. Li, and et al. Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner Protein Cell 2 2011 150 160
-
(2011)
Protein Cell
, vol.2
, pp. 150-160
-
-
Li, D.1
-
10
-
-
80054881600
-
Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin
-
D. Kaluza, and et al. Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin EMBO J. 30 2011 4142 4156
-
(2011)
EMBO J.
, vol.30
, pp. 4142-4156
-
-
Kaluza, D.1
-
11
-
-
0346020435
-
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
-
Y. Kawaguchi, and et al. The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress Cell 115 2003 727 738
-
(2003)
Cell
, vol.115
, pp. 727-738
-
-
Kawaguchi, Y.1
-
12
-
-
84890025789
-
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction
-
H.C. Lam, and et al. Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction J. Clin. Invest. 123 2013 5212 5230
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 5212-5230
-
-
Lam, H.C.1
-
13
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
U.B. Pandey, and et al. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS Nature 447 2007 859 863
-
(2007)
Nature
, vol.447
, pp. 859-863
-
-
Pandey, U.B.1
-
14
-
-
84938866406
-
Deacetylation of alpha-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly
-
J. Ran, and et al. Deacetylation of alpha-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly Sci. Rep. 5 2015 12917
-
(2015)
Sci. Rep.
, vol.5
, pp. 12917
-
-
Ran, J.1
-
15
-
-
34250758641
-
HEF1-dependent Aurora A activation induces disassembly of the primary cilium
-
E.N. Pugacheva, and et al. HEF1-dependent Aurora A activation induces disassembly of the primary cilium Cell 129 2007 1351 1363
-
(2007)
Cell
, vol.129
, pp. 1351-1363
-
-
Pugacheva, E.N.1
-
16
-
-
77954918703
-
Pitchfork regulates primary cilia disassembly and left-right asymmetry
-
D. Kinzel, and et al. Pitchfork regulates primary cilia disassembly and left-right asymmetry Dev. Cell 19 2010 66 77
-
(2010)
Dev. Cell
, vol.19
, pp. 66-77
-
-
Kinzel, D.1
-
17
-
-
84863934244
-
Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis
-
O.V. Plotnikova, and et al. Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis Mol. Biol. Cell 23 2012 2658 2670
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 2658-2670
-
-
Plotnikova, O.V.1
-
18
-
-
84890033642
-
The nephronophthisis gene product NPHP2/Inversin interacts with Aurora A and interferes with HDAC6-mediated cilia disassembly
-
M. Mergen, and et al. The nephronophthisis gene product NPHP2/Inversin interacts with Aurora A and interferes with HDAC6-mediated cilia disassembly Nephrol. Dial. Transplant. 28 2013 2744 2753
-
(2013)
Nephrol. Dial. Transplant.
, vol.28
, pp. 2744-2753
-
-
Mergen, M.1
-
19
-
-
84923376554
-
The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis
-
M. Kim, and et al. The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis Nat. Commun. 5 2014 5370
-
(2014)
Nat. Commun.
, vol.5
, pp. 5370
-
-
Kim, M.1
-
20
-
-
84924061350
-
Beta-catenin links von hippel-lindau to aurora kinase A and loss of primary cilia in renal cell carcinoma
-
R. Dere, and et al. beta-catenin links von hippel-lindau to aurora kinase A and loss of primary cilia in renal cell carcinoma J. Am. Soc. Nephrol. 26 2015 553 564
-
(2015)
J. Am. Soc. Nephrol.
, vol.26
, pp. 553-564
-
-
Dere, R.1
-
21
-
-
84908552874
-
CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6
-
Y. Yang, and et al. CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6 Cell Res. 24 2014 1342 1353
-
(2014)
Cell Res.
, vol.24
, pp. 1342-1353
-
-
Yang, Y.1
-
22
-
-
84897086955
-
Dido3-dependent HDAC6 targeting controls cilium size
-
A. Sanchez de Diego, and et al. Dido3-dependent HDAC6 targeting controls cilium size Nat. Commun. 5 2014 3500
-
(2014)
Nat. Commun.
, vol.5
, pp. 3500
-
-
Sanchez De Diego, A.1
-
23
-
-
84877908359
-
PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry
-
G. Wang, and et al. PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry J. Cell Sci. 126 2013 1355 1365
-
(2013)
J. Cell Sci.
, vol.126
, pp. 1355-1365
-
-
Wang, G.1
-
24
-
-
77953565925
-
The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis
-
Y. Li, and et al. The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis J. Cell Biol. 189 2010 1039 1051
-
(2010)
J. Cell Biol.
, vol.189
, pp. 1039-1051
-
-
Li, Y.1
-
25
-
-
57049171416
-
A BBSome subunit links ciliogenesis, microtubule stability, and acetylation
-
A.V. Loktev, and et al. A BBSome subunit links ciliogenesis, microtubule stability, and acetylation Dev. Cell 15 2008 854 865
-
(2008)
Dev. Cell
, vol.15
, pp. 854-865
-
-
Loktev, A.V.1
-
26
-
-
84883155892
-
Development and therapeutic implications of selective histone deacetylase 6 inhibitors
-
J.H. Kalin, and J.A. Bergman Development and therapeutic implications of selective histone deacetylase 6 inhibitors J. Med. Chem. 56 2013 6297 6313
-
(2013)
J. Med. Chem.
, vol.56
, pp. 6297-6313
-
-
Kalin, J.H.1
Bergman, J.A.2
-
27
-
-
84934980208
-
Histone deacetylases: structural determinants of inhibitor selectivity
-
C. Micelli, and G. Rastelli Histone deacetylases: structural determinants of inhibitor selectivity Drug Discov. Today 20 2015 718 735
-
(2015)
Drug Discov. Today
, vol.20
, pp. 718-735
-
-
Micelli, C.1
Rastelli, G.2
-
28
-
-
84892942381
-
New and emerging HDAC inhibitors for cancer treatment
-
A.C. West, and R.W. Johnstone New and emerging HDAC inhibitors for cancer treatment J. Clin. Invest. 124 2014 30 39
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 30-39
-
-
West, A.C.1
Johnstone, R.W.2
-
29
-
-
84876011387
-
HDAC6 inhibition restores ciliary expression and decreases tumor growth
-
S.A. Gradilone, and et al. HDAC6 inhibition restores ciliary expression and decreases tumor growth Cancer Res. 73 2013 2259 2270
-
(2013)
Cancer Res.
, vol.73
, pp. 2259-2270
-
-
Gradilone, S.A.1
-
30
-
-
0344640906
-
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
-
S.J. Haggarty, and et al. Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation Proc. Natl. Acad. Sci. U.S.A. 100 2003 4389 4394
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 4389-4394
-
-
Haggarty, S.J.1
-
31
-
-
70350771277
-
Centrioles, centrosomes, and cilia in health and disease
-
E.A. Nigg, and J.W. Raff Centrioles, centrosomes, and cilia in health and disease Cell 139 2009 663 678
-
(2009)
Cell
, vol.139
, pp. 663-678
-
-
Nigg, E.A.1
Raff, J.W.2
-
32
-
-
84866844040
-
Chronic obstructive pulmonary disease
-
H. Brody Chronic obstructive pulmonary disease Nature 489 2012 S1
-
(2012)
Nature
, vol.489
, pp. S1
-
-
Brody, H.1
-
33
-
-
80052446941
-
Ciliopathies: an expanding disease spectrum
-
A.M. Waters, and P.L. Beales Ciliopathies: an expanding disease spectrum Pediatr. Nephrol. 26 2011 1039 1056
-
(2011)
Pediatr. Nephrol.
, vol.26
, pp. 1039-1056
-
-
Waters, A.M.1
Beales, P.L.2
-
34
-
-
76049128716
-
Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models
-
Y. Cao, and et al. Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models Proc. Natl. Acad. Sci. U.S.A. 106 2009 21819 21824
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 21819-21824
-
-
Cao, Y.1
-
35
-
-
40749161986
-
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally
-
Y. Zhang, and et al. Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally Mol. Cell. Biol. 28 2008 1688 1701
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 1688-1701
-
-
Zhang, Y.1
-
36
-
-
37549010715
-
Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis
-
Y.S. Gao, and et al. Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis Mol. Cell. Biol. 27 2007 8637 8647
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 8637-8647
-
-
Gao, Y.S.1
|