Proteomic identification and functional characterization of MYH9, Hsc70, and DNAJA1 as novel substrates of HDAC6 deacetylase activity

Protein and Cell

Volumn 6, Issue 1, 2015, Pages 42-54

  Zhang, Linlin ^a   Liu, Shanshan ^a,b   Liu, Ningning ^a   Zhang, Yong ^a,b   Liu, Min ^a   Li, Dengwen ^a   Seto, Edward ^c   Yao, Tso Pang ^d   Shui, Wenqing ^a,b   Zhou, Jun ^a  

^a NANKAI UNIVERSITY   (China)

^b High throughput Molecular Drug Discovery Center   (China)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

HDAC6; interaction; lysine acetylation; quantitative proteomics; substrate

Indexed keywords

HEAT SHOCK COGNATE PROTEIN 70; HISTONE DEACETYLASE 11; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE 7; HISTONE DEACETYLASE 9; MYOSIN HEAVY CHAIN 9; PEPTIDES AND PROTEINS; PLASMID VECTOR; PROTEIN DNAJ 1; SIRTUIN 2; UNCLASSIFIED DRUG; ACTIN; DNAJA1 PROTEIN, MOUSE; HDAC6 PROTEIN, MOUSE; HEAT SHOCK PROTEIN 40; HISTONE DEACETYLASE; LYSINE; MYH9 PROTEIN, MOUSE; MYOSIN IIA; PROTEIN BINDING;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DATA ANALYSIS; DOWN REGULATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; FUNCTIONAL PROTEOMICS; GENETIC TRANSFECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; ISOTOPE LABELING; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN EXPRESSION; PROTEIN ISOLATION; REGULATORY MECHANISM; ACETYLATION; ANIMAL; C57BL MOUSE; CELL LINE; CHEMISTRY; CONFOCAL MICROSCOPY; ENZYME SPECIFICITY; KNOCKOUT MOUSE; LIVER; METABOLISM; PROTEOMICS; TANDEM MASS SPECTROMETRY;

ACETYLATION; ACTINS; ANIMALS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HISTONE DEACETYLASES; HSC70 HEAT-SHOCK PROTEINS; HSP40 HEAT-SHOCK PROTEINS; ISOTOPE LABELING; LIVER; LYSINE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; NONMUSCLE MYOSIN TYPE IIA; PROTEIN BINDING; PROTEOMICS; SUBSTRATE SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84922080063     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-014-0102-8     Document Type: Article

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