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Volumn 6, Issue , 2016, Pages

Cep70 overexpression stimulates pancreatic cancer by inducing centrosome abnormality and microtubule disorganization

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CEP70 PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN;

EID: 84959010938     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep21263     Document Type: Article
Times cited : (16)

References (39)
  • 1
    • 84883670305 scopus 로고    scopus 로고
    • Recent progress in pancreatic cancer
    • Wolfgang, C. L. et al. Recent progress in pancreatic cancer. CA Cancer J Clin 63, 318-348 (2013)
    • (2013) CA Cancer J Clin , vol.63 , pp. 318-348
    • Wolfgang, C.L.1
  • 2
    • 84940984903 scopus 로고    scopus 로고
    • Emerging roles of microRNAs in pancreatic cancer diagnosis, therapy and prognosis (Review
    • Subramani, R. et al. Emerging roles of microRNAs in pancreatic cancer diagnosis, therapy and prognosis (Review) Int J Oncol ,47, 1203-1210(2015)
    • (2015) Int J Oncol , vol.47 , pp. 1203-1210
    • Subramani, R.1
  • 3
    • 84877087883 scopus 로고    scopus 로고
    • Treatment options for advanced pancreatic cancer: A review
    • Warsame, R. &Grothey, A. Treatment options for advanced pancreatic cancer: A review. Expert Rev Anticancer Ther 12, 1327-1336 (2012)
    • (2012) Expert Rev Anticancer Ther , vol.12 , pp. 1327-1336
    • Warsame, R.1    Grothey, A.2
  • 4
    • 38049040752 scopus 로고    scopus 로고
    • Adjuvant therapy for pancreatic cancer: A review
    • Zuckerman, D. S. &Ryan, D. P. Adjuvant therapy for pancreatic cancer: A review. Cancer 112, 243-249 (2008)
    • (2008) Cancer , vol.112 , pp. 243-249
    • Zuckerman, D.S.1    Ryan, D.P.2
  • 5
    • 84875159380 scopus 로고    scopus 로고
    • Pancreatic cancer genomics: Insights and opportunities for clinical translation
    • Makohon-Moore, A., Brosnan, J. A. &Iacobuzio-Donahue, C. A. Pancreatic cancer genomics: insights and opportunities for clinical translation. Genome Med 5, 26 (2013)
    • (2013) Genome Med , vol.5 , pp. 26
    • Makohon-Moore, A.1    Brosnan, J.A.2    Iacobuzio-Donahue, C.A.3
  • 6
    • 0035165047 scopus 로고    scopus 로고
    • Gemcitabine: Progress in the treatment of pancreatic cancer
    • Heinemann, V. Gemcitabine: progress in the treatment of pancreatic cancer. Oncology 60, 8-18 (2001)
    • (2001) Oncology , vol.60 , pp. 8-18
    • Heinemann, V.1
  • 7
    • 67149130222 scopus 로고    scopus 로고
    • Epigenetics and epigenetic alterations in pancreatic cancer
    • Omura, N. &Goggins, M. Epigenetics and epigenetic alterations in pancreatic cancer. Int J Clin Exp Pathol 2, 310-326 (2009)
    • (2009) Int J Clin Exp Pathol , vol.2 , pp. 310-326
    • Omura, N.1    Goggins, M.2
  • 8
    • 84913609142 scopus 로고    scopus 로고
    • The role of mitotic kinases in coupling the centrosome cycle with the assembly of the mitotic spindle
    • Wang, G., Jiang, Q. &Zhang, C. The role of mitotic kinases in coupling the centrosome cycle with the assembly of the mitotic spindle. J Cell Sci 127, 4111-4122 (2014)
    • (2014) J Cell Sci , vol.127 , pp. 4111-4122
    • Wang, G.1    Jiang, Q.2    Zhang, C.3
  • 9
    • 27844562705 scopus 로고    scopus 로고
    • Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects
    • Tachibana, K. E., Gonzalez, M. A., Guarguaglini, G., Nigg, E. A. &Laskey, R. A. Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects. EMBO Rep 6, 1052-1057 (2005)
    • (2005) EMBO Rep , vol.6 , pp. 1052-1057
    • Tachibana, K.E.1    Gonzalez, M.A.2    Guarguaglini, G.3    Nigg, E.A.4    Laskey, R.A.5
  • 10
    • 0036831681 scopus 로고    scopus 로고
    • Centrosome aberrations: Cause or consequence of cancer progression?
    • Nigg, E. A. Centrosome aberrations: cause or consequence of cancer progression? Nat Rev Cancer 2, 815-825 (2002)
    • (2002) Nat Rev Cancer , vol.2 , pp. 815-825
    • Nigg, E.A.1
  • 11
    • 0035188129 scopus 로고    scopus 로고
    • Managing the centrosome numbers game: From chaos to stability in cancer cell division
    • Brinkley, B. R. Managing the centrosome numbers game: from chaos to stability in cancer cell division. Trends Cell Biol 11, 18-21 (2001)
    • (2001) Trends Cell Biol , vol.11 , pp. 18-21
    • Brinkley, B.R.1
  • 12
    • 0037133211 scopus 로고    scopus 로고
    • Centrosome amplification drives chromosomal instability in breast tumor development
    • Lingle, W. L. et al. Centrosome amplification drives chromosomal instability in breast tumor development. Proc Natl Acad Sci USA 99, 1978-1983 (2002)
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 1978-1983
    • Lingle, W.L.1
  • 13
    • 84874589546 scopus 로고    scopus 로고
    • LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells
    • Fogeron, M. L. et al. LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. Nat Commun 4, 1531 (2013)
    • (2013) Nat Commun , vol.4 , pp. 1531
    • Fogeron, M.L.1
  • 14
    • 0346874342 scopus 로고    scopus 로고
    • Proteomic characterization of the human centrosome by protein correlation profiling
    • Andersen, J. S. et al. Proteomic characterization of the human centrosome by protein correlation profiling. Nature 426, 570-574 (2003)
    • (2003) Nature , vol.426 , pp. 570-574
    • Andersen, J.S.1
  • 15
    • 80052990215 scopus 로고    scopus 로고
    • CEP70 protein interacts with gamma-tubulin to localize at the centrosome and is critical for mitotic spindle assembly
    • Shi, X. et al. CEP70 protein interacts with gamma-tubulin to localize at the centrosome and is critical for mitotic spindle assembly. J Biol Chem 286, 33401-33408 (2011)
    • (2011) J Biol Chem , vol.286 , pp. 33401-33408
    • Shi, X.1
  • 16
    • 84860329496 scopus 로고    scopus 로고
    • Cep70 contributes to angiogenesis by modulating microtubule rearrangement and stimulating cell polarization and migration
    • Shi, X. et al. Cep70 contributes to angiogenesis by modulating microtubule rearrangement and stimulating cell polarization and migration. Cell Cycle 11, 1554-1563 (2012)
    • (2012) Cell Cycle , vol.11 , pp. 1554-1563
    • Shi, X.1
  • 17
    • 80054018263 scopus 로고    scopus 로고
    • Scaffolding function of the Chlamydomonas procentriole protein CRC70, a member of the conserved Cep70 family
    • Shiratsuchi, G., Kamiya, R. &Hirono, M. Scaffolding function of the Chlamydomonas procentriole protein CRC70, a member of the conserved Cep70 family. J Cell Sci 124, 2964-2975 (2011)
    • (2011) J Cell Sci , vol.124 , pp. 2964-2975
    • Shiratsuchi, G.1    Kamiya, R.2    Hirono, M.3
  • 18
    • 63849188695 scopus 로고    scopus 로고
    • Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos
    • Wilkinson, C. J., Carl, M. &Harris, W. A. Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos. BMC Cell Biol 10, 17 (2009)
    • (2009) BMC Cell Biol , vol.10 , pp. 17
    • Wilkinson, C.J.1    Carl, M.2    Harris, W.A.3
  • 19
    • 84908552874 scopus 로고    scopus 로고
    • CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6
    • Yang, Y. et al. CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6. Cell Res 24, 1342-1353 (2014)
    • (2014) Cell Res , vol.24 , pp. 1342-1353
    • Yang, Y.1
  • 20
    • 0027482192 scopus 로고
    • Gene amplification: A target for cancer therapy
    • Harris, A. L. Gene amplification: A target for cancer therapy. Lancet 342, 1172 (1993)
    • (1993) Lancet , vol.342 , pp. 1172
    • Harris, A.L.1
  • 21
    • 77952759760 scopus 로고    scopus 로고
    • Ectopic expression of the microtubule-dependent motor protein Eg5 promotes pancreatic tumourigenesis
    • Liu, M. et al. Ectopic expression of the microtubule-dependent motor protein Eg5 promotes pancreatic tumourigenesis. J Pathol 221, 221-228 (2010)
    • (2011) J Pathol , vol.221 , pp. 221-228
    • Liu, M.1
  • 22
    • 84875047028 scopus 로고    scopus 로고
    • Advancements in the management of pancreatic cancer: 2013
    • Saif, M. W. Advancements in the management of pancreatic cancer: 2013. JOP 14, 112-118 (2013)
    • (2013) JOP , vol.14 , pp. 112-118
    • Saif, M.W.1
  • 23
    • 84898445760 scopus 로고    scopus 로고
    • Epigenetic targeting in pancreatic cancer
    • van Kampen, J. G. et al. Epigenetic targeting in pancreatic cancer. Cancer Treat Rev 40, 656-664 (2014)
    • (2014) Cancer Treat Rev , vol.40 , pp. 656-664
    • Van Kampen, J.G.1
  • 24
    • 84883410708 scopus 로고    scopus 로고
    • Epigenetic regulation of SOX9 by the NF-kappaB signaling pathway in pancreatic cancer stem cells
    • Sun, L. et al. Epigenetic regulation of SOX9 by the NF-kappaB signaling pathway in pancreatic cancer stem cells. Stem Cells 31, 1454-1466 (2013)
    • (2013) Stem Cells , vol.31 , pp. 1454-1466
    • Sun, L.1
  • 25
    • 0037672151 scopus 로고    scopus 로고
    • Polo-like kinase 1 regulates nlp, a centrosome protein involved in microtubule nucleation
    • Casenghi, M. et al. Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. Dev Cell 5, 113-125 (2003)
    • (2003) Dev Cell , vol.5 , pp. 113-125
    • Casenghi, M.1
  • 26
    • 77958017958 scopus 로고    scopus 로고
    • Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells
    • Montanez-Wiscovich, M. E. et al. Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells. J Pathol 222, 271-281 (2010)
    • (2011) J Pathol , vol.222 , pp. 271-281
    • Montanez-Wiscovich, M.E.1
  • 28
    • 84891122759 scopus 로고    scopus 로고
    • Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer
    • Pihan, G. A. Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer. Front Oncol 3, 277 (2013)
    • (2013) Front Oncol , vol.3 , pp. 277
    • Pihan, G.A.1
  • 29
    • 44649117902 scopus 로고    scopus 로고
    • Centrosome amplification can initiate tumorigenesis in flies
    • Basto, R. et al. Centrosome amplification can initiate tumorigenesis in flies. Cell 133, 1032-1042 (2008)
    • (2008) Cell , vol.133 , pp. 1032-1042
    • Basto, R.1
  • 30
    • 23844444229 scopus 로고    scopus 로고
    • Experimental trial for diagnosis of pancreatic ductal carcinoma based on gene expression profiles of pancreatic ductal cells
    • Ishikawa, M. et al. Experimental trial for diagnosis of pancreatic ductal carcinoma based on gene expression profiles of pancreatic ductal cells. Cancer Sci 96, 387-393 (2005)
    • (2005) Cancer Sci , vol.96 , pp. 387-393
    • Ishikawa, M.1
  • 31
    • 66749185308 scopus 로고    scopus 로고
    • Parkin regulates paclitaxel sensitivity in breast cancer via a microtubule-dependent mechanism
    • Wang, H. et al. Parkin regulates paclitaxel sensitivity in breast cancer via a microtubule-dependent mechanism. J Pathol 218, 76-85 (2009)
    • (2009) J Pathol , vol.218 , pp. 76-85
    • Wang, H.1
  • 32
    • 84862776774 scopus 로고    scopus 로고
    • Microtubule-binding protein CLIP-170 is a mediator of paclitaxel sensitivity
    • Sun, X. et al. Microtubule-binding protein CLIP-170 is a mediator of paclitaxel sensitivity. J Pathol 226, 666-673 (2012)
    • (2012) J Pathol , vol.226 , pp. 666-673
    • Sun, X.1
  • 33
    • 84875909195 scopus 로고    scopus 로고
    • Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation
    • Sun, X. et al. Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation. Cell Cycle 12, 1133-1141 (2013)
    • (2013) Cell Cycle , vol.12 , pp. 1133-1141
    • Sun, X.1
  • 34
    • 84900811585 scopus 로고    scopus 로고
    • Modulation of Eg5 activity contributes to mitotic spindle checkpoint activation and Tat-mediated apoptosis in CD4-positive T-lymphocytes
    • Liu, M. et al. Modulation of Eg5 activity contributes to mitotic spindle checkpoint activation and Tat-mediated apoptosis in CD4-positive T-lymphocytes. J Pathol 233, 138-147 (2014)
    • (2014) J Pathol , vol.233 , pp. 138-147
    • Liu, M.1
  • 35
    • 84906859546 scopus 로고    scopus 로고
    • Microtubule-Associated protein Mdp3 promotes breast cancer growth and metastasis
    • Microtubule-Associated protein Mdp3 promotes breast cancer growth and metastasis. Theranostics 4, 1052-1061 (2014)
    • (2014) Theranostics , vol.4 , pp. 1052-1061
  • 36
    • 75749090019 scopus 로고    scopus 로고
    • Oncogenic function of microtubule end-binding protein 1 in breast cancer
    • Dong, X. et al. Oncogenic function of microtubule end-binding protein 1 in breast cancer. J Pathol 220, 361-369 (2010)
    • (2011) J Pathol , vol.220 , pp. 361-369
    • Dong, X.1
  • 37
    • 77953284316 scopus 로고    scopus 로고
    • CYLD regulates angiogenesis by mediating vascular endothelial cell migration
    • Gao, J. et al. CYLD regulates angiogenesis by mediating vascular endothelial cell migration. Blood 115, 4130-4137 (2010)
    • (2011) Blood , vol.115 , pp. 4130-4137
    • Gao, J.1
  • 38
    • 84893848639 scopus 로고    scopus 로고
    • CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation
    • Yang, Y. et al. CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation. Proc Natl Acad Sci USA 111, 2158-2163 (2014)
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 2158-2163
    • Yang, Y.1
  • 39
    • 78650004788 scopus 로고    scopus 로고
    • Tat acetylation regulates its actions on microtubule dynamics and apoptosis in T lymphocytes
    • Huo, L. et al. Tat acetylation regulates its actions on microtubule dynamics and apoptosis in T lymphocytes. J Pathol 223, 28-36 (2011)
    • (2011) J Pathol , vol.223 , pp. 28-36
    • Huo, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.