TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus

Journal of Cell Science

Volumn 129, Issue 9, 2016, Pages 1855-1865

  Sai, Kazuhito ^a,b   Morioka, Sho ^b,c   Takaesu, Giichi ^b,d   Muthusamy, Nagendran ^b   Ghashghaei, H Troy ^b   Hanafusa, Hiroshi ^a   Matsumoto, Kunihiro ^a   Ninomiya Tsuji, Jun ^b  

^a NAGOYA UNIVERSITY   (Japan)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

Endoplasmic reticulum stress; Hypothalamus; Leptin; Obesity; TAK1

Indexed keywords

LEPTIN; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; FAT INTAKE; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; STEROL REGULATORY ELEMENT BINDING PROTEIN;

ANIMAL CELL; ARTICLE; BIOGENESIS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE DELETION; HYPOTHALAMUS; LIPID DIET; LIPOGENESIS; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; UPREGULATION; ADVERSE EFFECTS; ANIMAL; CHEMICALLY INDUCED; FAT INTAKE; GENETICS; HYPERPHAGIA; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHARMACOLOGY;

ANIMALS; DIETARY FATS; ENDOPLASMIC RETICULUM STRESS; HYPERPHAGIA; HYPOTHALAMUS; LEPTIN; MAP KINASE KINASE KINASES; MICE; MICE, KNOCKOUT; OBESITY; STEROL REGULATORY ELEMENT BINDING PROTEINS;

EID: 84968866114     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.180505     Document Type: Article

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