TGF-β-activated kinase 1 signaling maintains intestinal integrity by preventing accumulation of reactive oxygen species in the intestinal epithelium

Journal of Immunology

Volumn 185, Issue 8, 2010, Pages 4729-4737

  Kajino Sakamoto, Rie ^a   Omori, Emily ^a   Nighot, Prashant K ^a   Blikslager, Anthony T ^a   Matsumoto, Kunihiro ^b   Ninomiya Tsuji, Jun ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENTERITIS; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; INTESTINE CELL; INTESTINE EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SIGNAL TRANSDUCTION; TISSUE INJURY; ANIMAL; C57BL MOUSE; ENZYMOLOGY; EPITHELIUM; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INTESTINE MUCOSA; METABOLISM; MUCOSAL IMMUNITY; OXIDATIVE STRESS; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; EPITHELIUM; GENE EXPRESSION; GENE EXPRESSION REGULATION; IMMUNITY, MUCOSAL; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MAP KINASE KINASE KINASES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 78049504143     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903587     Document Type: Article

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