Inhibition of autophagy potentiates anticancer property of 20(S)-ginsenoside Rh2 by promoting mitochondria-dependent apoptosis in human acute lymphoblastic leukaemia cells

Oncotarget

Volumn 7, Issue 19, 2016, Pages 27336-27349

  Xia, Ting ^a   Wang, Jiancheng ^b   Wang, Yingnan ^b   Wang, Yuanyuan ^b   Cai, Jianye ^b   Wang, Min ^a   Chen, Qidan ^c   Song, Jia ^a   Yu, Ziqi ^a   Huang, Wei ^a   Fang, Jianpei ^b  

^a TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c JILIN UNIVERSITY   (China)

Author keywords

Acute lymphoblastic leukaemia; Apoptosis; Autophagy; Ginsenoside Rh2; Mitochondria

Indexed keywords

GINSENOSIDE RH 2; MATRIX METALLOPROTEINASE; REACTIVE OXYGEN METABOLITE; 3-METHYLADENINE; ADENINE; ANTINEOPLASTIC AGENT; ATG5 PROTEIN, HUMAN; AUTOPHAGY RELATED PROTEIN 5; GINSENOSIDE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; MITOCHONDRION; ANALOGS AND DERIVATIVES; CELL CULTURE; CELL SURVIVAL; DRUG EFFECTS; GENETICS; JURKAT CELL LINE; METABOLISM; PATHOLOGY; RNA INTERFERENCE; TUMOR CELL LINE;

ADENINE; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 5; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; GINSENOSIDES; HUMANS; JURKAT CELLS; MITOCHONDRIA; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE;

EID: 84968754597     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.8285     Document Type: Article

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