Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53

Cancer Letters

Volumn 301, Issue 2, 2011, Pages 185-192

  Li, Binghui ^a   Zhao, Jiong ^a   Wang, Chong Zhi ^b,c   Searle, Jennifer ^a   He, Tong Chuan ^b,c   Yuan, Chun Su ^b,c   Du, Wei ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

Antioxidant; Apoptosis; Ginsenoside; NF B; ROS

Indexed keywords

ACETYLCYSTEINE; CASPASE; CATALASE; GINSENOSIDE RG 3; GINSENOSIDE RH 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL STRAIN HCT116; CELL VACUOLE; COLORECTAL CANCER; CONTROLLED STUDY; CYTOPLASM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

ACETYLCYSTEINE; AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; CASPASES; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; COLORECTAL NEOPLASMS; CYSTEINE PROTEINASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FREE RADICAL SCAVENGERS; GINSENOSIDES; HCT116 CELLS; HEK293 CELLS; HUMANS; MUTATION; NF-KAPPA B; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; VACUOLES;

PANAX QUINQUEFOLIUS;

EID: 78651445610     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2010.11.015     Document Type: Article

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