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Volumn 27, Issue 7, 2016, Pages 493-503

Type 1 Diabetes and Dysfunctional Intestinal Homeostasis

Author keywords

Circulating enterotrophic hormones; Diabetic enteropathy; Gastrointestinal disorders; Intestinal stem cells

Indexed keywords

ADALIMUMAB; AMINOSALICYLIC ACID; ANTIBIOTIC AGENT; ANTIINFLAMMATORY AGENT; AZATHIOPRINE; CORTICOSTEROID; CYTOKINE; DIPHENOXYLATE; GASTROINTESTINAL HORMONE; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; LOPERAMIDE; METFORMIN; METHOTREXATE; NEUROTRANSMITTER; OCTREOTIDE; USTEKINUMAB;

EID: 84966716353     PISSN: 10432760     EISSN: 18793061     Source Type: Journal    
DOI: 10.1016/j.tem.2016.04.005     Document Type: Review
Times cited : (32)

References (90)
  • 1
    • 0014019131 scopus 로고
    • Gastrointestinal manifestations of diabetes
    • Katz L.A., Spiro H.M. Gastrointestinal manifestations of diabetes. N. Engl. J. Med. 1966, 275:1350-1361.
    • (1966) N. Engl. J. Med. , vol.275 , pp. 1350-1361
    • Katz, L.A.1    Spiro, H.M.2
  • 2
    • 0020686499 scopus 로고
    • Disorders of gastrointestinal motility associated with diabetes mellitus
    • Feldman M., Schiller L.R. Disorders of gastrointestinal motility associated with diabetes mellitus. Ann. Internal Med. 1983, 98:378-384.
    • (1983) Ann. Internal Med. , vol.98 , pp. 378-384
    • Feldman, M.1    Schiller, L.R.2
  • 3
    • 0032703085 scopus 로고    scopus 로고
    • Gastrointestinal symptoms in Chinese patients with type 2 diabetes mellitus
    • Ko G.T., et al. Gastrointestinal symptoms in Chinese patients with type 2 diabetes mellitus. Diabetic Med. 1999, 16:670-674.
    • (1999) Diabetic Med. , vol.16 , pp. 670-674
    • Ko, G.T.1
  • 4
    • 0035955922 scopus 로고    scopus 로고
    • Prevalence of gastrointestinal symptoms associated with diabetes mellitus: a population-based survey of 15,000 adults
    • Bytzer P., et al. Prevalence of gastrointestinal symptoms associated with diabetes mellitus: a population-based survey of 15,000 adults. Arch. Internal Med. 2001, 161:1989-1996.
    • (2001) Arch. Internal Med. , vol.161 , pp. 1989-1996
    • Bytzer, P.1
  • 5
    • 0036127907 scopus 로고    scopus 로고
    • GI symptoms in diabetes mellitus are associated with both poor glycemic control and diabetic complications
    • Bytzer P., et al. GI symptoms in diabetes mellitus are associated with both poor glycemic control and diabetic complications. Am. J. Gastroenterol. 2002, 97:604-611.
    • (2002) Am. J. Gastroenterol. , vol.97 , pp. 604-611
    • Bytzer, P.1
  • 6
    • 0035133296 scopus 로고    scopus 로고
    • Impact of chronic gastrointestinal symptoms in diabetes mellitus on health-related quality of life
    • Talley N.J., et al. Impact of chronic gastrointestinal symptoms in diabetes mellitus on health-related quality of life. Am. J. Gastroenterol. 2001, 96:71-76.
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 71-76
    • Talley, N.J.1
  • 7
    • 84957431598 scopus 로고    scopus 로고
    • Gastrointestinal autonomic neuropathy in diabetes: the unattended borderline between diabetology and gastroenterology
    • Kempler P., et al. Gastrointestinal autonomic neuropathy in diabetes: the unattended borderline between diabetology and gastroenterology. Diabetologia 2016, 59:401-403.
    • (2016) Diabetologia , vol.59 , pp. 401-403
    • Kempler, P.1
  • 8
  • 9
    • 37249093549 scopus 로고    scopus 로고
    • Interstitial cells of Cajal in diabetic gastroenteropathy
    • Ordog T. Interstitial cells of Cajal in diabetic gastroenteropathy. Neurogastroenterol. Motil. 2008, 20:8-18.
    • (2008) Neurogastroenterol. Motil. , vol.20 , pp. 8-18
    • Ordog, T.1
  • 10
    • 0033030001 scopus 로고    scopus 로고
    • Diabetic gastropathy: gastric neuromuscular dysfunction in diabetes mellitus: a review of symptoms, pathophysiology, and treatment
    • Koch K.L. Diabetic gastropathy: gastric neuromuscular dysfunction in diabetes mellitus: a review of symptoms, pathophysiology, and treatment. Dig. Dis. Sci. 1999, 44:1061-1075.
    • (1999) Dig. Dis. Sci. , vol.44 , pp. 1061-1075
    • Koch, K.L.1
  • 11
    • 0035141010 scopus 로고    scopus 로고
    • Relationships of upper gastrointestinal motor and sensory function with glycemic control
    • Rayner C.K., et al. Relationships of upper gastrointestinal motor and sensory function with glycemic control. Diabetes Care 2001, 24:371-381.
    • (2001) Diabetes Care , vol.24 , pp. 371-381
    • Rayner, C.K.1
  • 12
    • 0042405193 scopus 로고    scopus 로고
    • Diabetic autonomic neuropathy
    • Vinik A.I., et al. Diabetic autonomic neuropathy. Diabetes Care 2003, 26:1553-1579.
    • (2003) Diabetes Care , vol.26 , pp. 1553-1579
    • Vinik, A.I.1
  • 13
    • 32444450603 scopus 로고    scopus 로고
    • GDNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathway
    • Anitha M., et al. GDNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathway. J. Clin. Invest. 2006, 116:344-356.
    • (2006) J. Clin. Invest. , vol.116 , pp. 344-356
    • Anitha, M.1
  • 14
    • 78651419160 scopus 로고    scopus 로고
    • Colonic motor dysfunction in human diabetes is associated with enteric neuronal loss and increased oxidative stress
    • Chandrasekharan B., et al. Colonic motor dysfunction in human diabetes is associated with enteric neuronal loss and increased oxidative stress. Neurogastroenterol. Motil. 2011, 23:131-138.
    • (2011) Neurogastroenterol. Motil. , vol.23 , pp. 131-138
    • Chandrasekharan, B.1
  • 15
    • 79951626557 scopus 로고    scopus 로고
    • Neuroprotective properties of GLP-1: theoretical and practical applications
    • Holst J.J., et al. Neuroprotective properties of GLP-1: theoretical and practical applications. Curr. Med. Res. Opin. 2011, 27:547-558.
    • (2011) Curr. Med. Res. Opin. , vol.27 , pp. 547-558
    • Holst, J.J.1
  • 16
    • 84952333567 scopus 로고    scopus 로고
    • Enteroendocrine cells: a review of their role in brain-gut communication
    • Latorre R., et al. Enteroendocrine cells: a review of their role in brain-gut communication. Neurogastroenterol. Motil. 2016, 28:620-630.
    • (2016) Neurogastroenterol. Motil. , vol.28 , pp. 620-630
    • Latorre, R.1
  • 17
    • 0042405175 scopus 로고    scopus 로고
    • Long-term beneficial effect of islet transplantation on diabetic macro-/microangiopathy in type 1 diabetic kidney-transplanted patients
    • Fiorina P., et al. Long-term beneficial effect of islet transplantation on diabetic macro-/microangiopathy in type 1 diabetic kidney-transplanted patients. Diabetes Care 2003, 26:1129-1136.
    • (2003) Diabetes Care , vol.26 , pp. 1129-1136
    • Fiorina, P.1
  • 18
    • 84881479285 scopus 로고    scopus 로고
    • Serotonin signalling in the gut-functions, dysfunctions and therapeutic targets
    • Mawe G.M., Hoffman J.M. Serotonin signalling in the gut-functions, dysfunctions and therapeutic targets. Nat. Rev. Gastroenterol. Hepatol. 2013, 10:473-486.
    • (2013) Nat. Rev. Gastroenterol. Hepatol. , vol.10 , pp. 473-486
    • Mawe, G.M.1    Hoffman, J.M.2
  • 19
    • 70350087382 scopus 로고    scopus 로고
    • Physiology, injury, and recovery of interstitial cells of Cajal: basic and clinical science
    • Huizinga J.D., et al. Physiology, injury, and recovery of interstitial cells of Cajal: basic and clinical science. Gastroenterology 2009, 137:1548-1556.
    • (2009) Gastroenterology , vol.137 , pp. 1548-1556
    • Huizinga, J.D.1
  • 20
    • 0035993278 scopus 로고    scopus 로고
    • The prevalence of gastrointestinal symptoms in patients with chronic renal failure is increased and associated with impaired psychological general well-being
    • Strid H., et al. The prevalence of gastrointestinal symptoms in patients with chronic renal failure is increased and associated with impaired psychological general well-being. Nephrol. Dial. Transplant. 2002, 17:1434-1439.
    • (2002) Nephrol. Dial. Transplant. , vol.17 , pp. 1434-1439
    • Strid, H.1
  • 21
    • 58149091806 scopus 로고    scopus 로고
    • The "perfect storm" for type 1 diabetes: the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity
    • Vaarala O., et al. The "perfect storm" for type 1 diabetes: the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity. Diabetes 2008, 57:2555-2562.
    • (2008) Diabetes , vol.57 , pp. 2555-2562
    • Vaarala, O.1
  • 22
    • 84884590309 scopus 로고    scopus 로고
    • Human intestinal microbiota and type 1 diabetes
    • Vaarala O. Human intestinal microbiota and type 1 diabetes. Curr. Diabetes Rep. 2013, 13:601-607.
    • (2013) Curr. Diabetes Rep. , vol.13 , pp. 601-607
    • Vaarala, O.1
  • 23
    • 84941948674 scopus 로고    scopus 로고
    • Diabetes-related dysfunction of the small intestine and the colon: focus on motility
    • Horvath V.J., et al. Diabetes-related dysfunction of the small intestine and the colon: focus on motility. Curr. Diabetes Rep. 2015, 15:94.
    • (2015) Curr. Diabetes Rep. , vol.15 , pp. 94
    • Horvath, V.J.1
  • 24
    • 82355190060 scopus 로고    scopus 로고
    • Morphofunctional changes underlying intestinal dysmotility in diabetic RIP-I/hIFNbeta transgenic mice
    • Domenech A., et al. Morphofunctional changes underlying intestinal dysmotility in diabetic RIP-I/hIFNbeta transgenic mice. Int. J. Exp. Pathol. 2011, 92:400-412.
    • (2011) Int. J. Exp. Pathol. , vol.92 , pp. 400-412
    • Domenech, A.1
  • 25
    • 7644240770 scopus 로고    scopus 로고
    • Regeneration of injured intestinal mucosa is impaired in hepatocyte growth factor activator-deficient mice
    • Itoh H., et al. Regeneration of injured intestinal mucosa is impaired in hepatocyte growth factor activator-deficient mice. Gastroenterology 2004, 127:1423-1435.
    • (2004) Gastroenterology , vol.127 , pp. 1423-1435
    • Itoh, H.1
  • 26
    • 84871924611 scopus 로고    scopus 로고
    • In vivo characterization of intestinal effects of endomorphin-1 and endomorphin-2 in type 1 diabetic mice
    • Wang C.L., et al. In vivo characterization of intestinal effects of endomorphin-1 and endomorphin-2 in type 1 diabetic mice. Eur. J. Pharmacol. 2013, 698:499-504.
    • (2013) Eur. J. Pharmacol. , vol.698 , pp. 499-504
    • Wang, C.L.1
  • 27
    • 79959238013 scopus 로고    scopus 로고
    • Microenvironmental regulation of stem cells in intestinal homeostasis and cancer
    • Medema J.P., Vermeulen L. Microenvironmental regulation of stem cells in intestinal homeostasis and cancer. Nature 2011, 474:318-326.
    • (2011) Nature , vol.474 , pp. 318-326
    • Medema, J.P.1    Vermeulen, L.2
  • 28
    • 80053978141 scopus 로고    scopus 로고
    • Isolation and in vitro expansion of human colonic stem cells
    • Jung P., et al. Isolation and in vitro expansion of human colonic stem cells. Nat. Med. 2011, 17:1225-1227.
    • (2011) Nat. Med. , vol.17 , pp. 1225-1227
    • Jung, P.1
  • 29
    • 84962176452 scopus 로고    scopus 로고
    • Cancer risk among people with type 1 and type 2 diabetes: disentangling true associations, detection bias, and reverse causation. Diabetes Care 2015; 38: 264-270
    • Harding J.L., et al. Cancer risk among people with type 1 and type 2 diabetes: disentangling true associations, detection bias, and reverse causation. Diabetes Care 2015; 38: 264-270. Diabetes Care 2015, 38:734-735.
    • (2015) Diabetes Care , vol.38 , pp. 734-735
    • Harding, J.L.1
  • 30
    • 80655127682 scopus 로고    scopus 로고
    • Is diabetes mellitus an independent risk factor for colon cancer and rectal cancer?
    • quiz 1922
    • Yuhara H., et al. Is diabetes mellitus an independent risk factor for colon cancer and rectal cancer?. Am. J. Gastroenterol. 2011, 106:1911-1921. quiz 1922.
    • (2011) Am. J. Gastroenterol. , vol.106 , pp. 1911-1921
    • Yuhara, H.1
  • 31
    • 84960483396 scopus 로고    scopus 로고
    • The activation of ERK1/2 and JNK MAPK signaling by insulin/IGF-1 is responsible for the development of colon cancer with type 2 diabetes mellitus
    • Teng J.A., et al. The activation of ERK1/2 and JNK MAPK signaling by insulin/IGF-1 is responsible for the development of colon cancer with type 2 diabetes mellitus. PLoS ONE 2016, 11:e0149822.
    • (2016) PLoS ONE , vol.11
    • Teng, J.A.1
  • 32
    • 84952322017 scopus 로고    scopus 로고
    • IGFBP3 and T1D: systemic factors in colonic stem cell function and diabetic enteropathy
    • Cheng C.W., Yilmaz O.H. IGFBP3 and T1D: systemic factors in colonic stem cell function and diabetic enteropathy. Cell Stem Cell 2015, 17:379-380.
    • (2015) Cell Stem Cell , vol.17 , pp. 379-380
    • Cheng, C.W.1    Yilmaz, O.H.2
  • 33
    • 84947617793 scopus 로고    scopus 로고
    • Diabetes: circulating factors implicated in diabetic enteropathy
    • Thomas H. Diabetes: circulating factors implicated in diabetic enteropathy. Nat. Rev. Endocrinol. 2015, 11:688.
    • (2015) Nat. Rev. Endocrinol. , vol.11 , pp. 688
    • Thomas, H.1
  • 34
    • 84949091544 scopus 로고    scopus 로고
    • Diabetes: circulating factors implicated in diabetic enteropathy
    • Thomas H. Diabetes: circulating factors implicated in diabetic enteropathy. Nat. Rev. Gastroenterol. Hepatol. 2015, 12:671.
    • (2015) Nat. Rev. Gastroenterol. Hepatol. , vol.12 , pp. 671
    • Thomas, H.1
  • 35
    • 84952313820 scopus 로고    scopus 로고
    • Circulating IGF-I and IGFBP3 levels control human colonic stem cell function and are disrupted in diabetic enteropathy
    • D'Addio F., et al. Circulating IGF-I and IGFBP3 levels control human colonic stem cell function and are disrupted in diabetic enteropathy. Cell Stem Cell 2015, 17:486-498.
    • (2015) Cell Stem Cell , vol.17 , pp. 486-498
    • D'Addio, F.1
  • 36
    • 0023832668 scopus 로고
    • GSRS-a clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease
    • Svedlund J., et al. GSRS-a clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease. Dig. Dis. Sci. 1988, 33:129-134.
    • (1988) Dig. Dis. Sci. , vol.33 , pp. 129-134
    • Svedlund, J.1
  • 37
    • 0024434354 scopus 로고
    • A patient questionnaire to identify bowel disease
    • Talley N.J., et al. A patient questionnaire to identify bowel disease. Ann. Internal Med. 1989, 111:671-674.
    • (1989) Ann. Internal Med. , vol.111 , pp. 671-674
    • Talley, N.J.1
  • 38
    • 84898804234 scopus 로고    scopus 로고
    • Traditional measures of normal anal sphincter function using high-resolution anorectal manometry (HRAM) in 115 healthy volunteers
    • Carrington E.V., et al. Traditional measures of normal anal sphincter function using high-resolution anorectal manometry (HRAM) in 115 healthy volunteers. Neurogastroenterol. Motil. 2014, 26:625-635.
    • (2014) Neurogastroenterol. Motil. , vol.26 , pp. 625-635
    • Carrington, E.V.1
  • 39
    • 70149106015 scopus 로고    scopus 로고
    • Assessing gastrointestinal symptoms and perception, quality of life, motility, and autonomic neuropathy in clinical studies
    • Portincasa P., et al. Assessing gastrointestinal symptoms and perception, quality of life, motility, and autonomic neuropathy in clinical studies. J. Gastrointest. Liver Dis. 2009, 18:205-211.
    • (2009) J. Gastrointest. Liver Dis. , vol.18 , pp. 205-211
    • Portincasa, P.1
  • 40
    • 62049085734 scopus 로고    scopus 로고
    • Optimal approach to obtaining mucosal biopsies for assessment of inflammatory disorders of the gastrointestinal tract
    • Yantiss R.K., Odze R.D. Optimal approach to obtaining mucosal biopsies for assessment of inflammatory disorders of the gastrointestinal tract. Am. J. Gastroenterol. 2009, 104:774-783.
    • (2009) Am. J. Gastroenterol. , vol.104 , pp. 774-783
    • Yantiss, R.K.1    Odze, R.D.2
  • 41
    • 84927130182 scopus 로고    scopus 로고
    • Imaging techniques in IBD and their role in follow-up and surveillance
    • Eliakim R., Magro F. Imaging techniques in IBD and their role in follow-up and surveillance. Nat. Rev. Gastroenterol. Hepatol. 2014, 11:722-736.
    • (2014) Nat. Rev. Gastroenterol. Hepatol. , vol.11 , pp. 722-736
    • Eliakim, R.1    Magro, F.2
  • 42
    • 84943255921 scopus 로고    scopus 로고
    • Stool testing for colorectal cancer screening
    • Robertson D.J., Imperiale T.F. Stool testing for colorectal cancer screening. Gastroenterology 2015, 149:1286-1293.
    • (2015) Gastroenterology , vol.149 , pp. 1286-1293
    • Robertson, D.J.1    Imperiale, T.F.2
  • 43
    • 84922418194 scopus 로고    scopus 로고
    • Fecal biomarkers in the diagnosis and monitoring of Crohn's disease
    • Wright E.K., et al. Fecal biomarkers in the diagnosis and monitoring of Crohn's disease. Inflamm. Bowel Dis. 2014, 20:1668-1677.
    • (2014) Inflamm. Bowel Dis. , vol.20 , pp. 1668-1677
    • Wright, E.K.1
  • 44
    • 84892480511 scopus 로고    scopus 로고
    • Effectiveness and cost-effectiveness of measuring fecal calprotectin in diagnosis of inflammatory bowel disease in adults and children
    • Yang Z., et al. Effectiveness and cost-effectiveness of measuring fecal calprotectin in diagnosis of inflammatory bowel disease in adults and children. Clin. Gastroenterol. Hepatol. 2014, 12:253-262.
    • (2014) Clin. Gastroenterol. Hepatol. , vol.12 , pp. 253-262
    • Yang, Z.1
  • 45
    • 84925779235 scopus 로고    scopus 로고
    • Magnetic resonance enterography: state of the art
    • Stoddard P.B., et al. Magnetic resonance enterography: state of the art. Inflamm. Bowel Dis. 2015, 21:229-239.
    • (2015) Inflamm. Bowel Dis. , vol.21 , pp. 229-239
    • Stoddard, P.B.1
  • 46
    • 84911490857 scopus 로고    scopus 로고
    • The quest for biomarkers in IBS-where should it lead us?
    • Corsetti M., et al. The quest for biomarkers in IBS-where should it lead us?. Neurogastroenterol. Motil. 2014, 26:1669-1676.
    • (2014) Neurogastroenterol. Motil. , vol.26 , pp. 1669-1676
    • Corsetti, M.1
  • 47
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med. 1993, 329:977-986.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 977-986
  • 48
    • 0035186582 scopus 로고    scopus 로고
    • Oral hypoglycaemic drugs and gastrointestinal symptoms in diabetes mellitus
    • Bytzer P., et al. Oral hypoglycaemic drugs and gastrointestinal symptoms in diabetes mellitus. Aliment. Pharmacol. Ther. 2001, 15:137-142.
    • (2001) Aliment. Pharmacol. Ther. , vol.15 , pp. 137-142
    • Bytzer, P.1
  • 49
    • 0027252577 scopus 로고
    • Chronic diarrhea in diabetes mellitus: mechanisms and an approach to diagnosis and treatment
    • Valdovinos M.A., et al. Chronic diarrhea in diabetes mellitus: mechanisms and an approach to diagnosis and treatment. Mayo Clinic Proc. 1993, 68:691-702.
    • (1993) Mayo Clinic Proc. , vol.68 , pp. 691-702
    • Valdovinos, M.A.1
  • 50
    • 0026492874 scopus 로고
    • Effective treatment of diabetic diarrhoea with somatostatin analogue, octreotide
    • Mourad F.H., et al. Effective treatment of diabetic diarrhoea with somatostatin analogue, octreotide. Gut 1992, 33:1578-1580.
    • (1992) Gut , vol.33 , pp. 1578-1580
    • Mourad, F.H.1
  • 51
    • 84892385279 scopus 로고    scopus 로고
    • Islet transplantation stabilizes hemostatic abnormalities and cerebral metabolism in individuals with type 1 diabetes
    • D'Addio F., et al. Islet transplantation stabilizes hemostatic abnormalities and cerebral metabolism in individuals with type 1 diabetes. Diabetes Care 2014, 37:267-276.
    • (2014) Diabetes Care , vol.37 , pp. 267-276
    • D'Addio, F.1
  • 52
    • 4344651590 scopus 로고    scopus 로고
    • Normalization of multiple hemostatic abnormalities in uremic type 1 diabetic patients after kidney-pancreas transplantation
    • Fiorina P., et al. Normalization of multiple hemostatic abnormalities in uremic type 1 diabetic patients after kidney-pancreas transplantation. Diabetes 2004, 53:2291-2300.
    • (2004) Diabetes , vol.53 , pp. 2291-2300
    • Fiorina, P.1
  • 53
    • 0037469055 scopus 로고    scopus 로고
    • Islet transplantation improves vascular diabetic complications in patients with diabetes who underwent kidney transplantation: a comparison between kidney-pancreas and kidney-alone transplantation
    • Fiorina P., et al. Islet transplantation improves vascular diabetic complications in patients with diabetes who underwent kidney transplantation: a comparison between kidney-pancreas and kidney-alone transplantation. Transplantation 2003, 75:1296-1301.
    • (2003) Transplantation , vol.75 , pp. 1296-1301
    • Fiorina, P.1
  • 54
    • 78649454844 scopus 로고    scopus 로고
    • Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients' skin which are normalized by kidney-pancreas transplantation
    • Folli F., et al. Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients' skin which are normalized by kidney-pancreas transplantation. PLoS ONE 2010, 5:e9923.
    • (2010) PLoS ONE , vol.5 , pp. e9923
    • Folli, F.1
  • 55
    • 84908296732 scopus 로고    scopus 로고
    • Development of drugs to target interactions between leukocytes and endothelial cells and treatment algorithms for inflammatory bowel diseases
    • Danese S., Panes J. Development of drugs to target interactions between leukocytes and endothelial cells and treatment algorithms for inflammatory bowel diseases. Gastroenterology 2014, 147:981-989.
    • (2014) Gastroenterology , vol.147 , pp. 981-989
    • Danese, S.1    Panes, J.2
  • 56
    • 4344602852 scopus 로고    scopus 로고
    • Guidelines for the management of inflammatory bowel disease in adults
    • Carter M.J., et al. Guidelines for the management of inflammatory bowel disease in adults. Gut 2004, 53(Suppl. 5):V1-V16.
    • (2004) Gut , vol.53 , pp. V1-V16
    • Carter, M.J.1
  • 57
    • 2542446343 scopus 로고    scopus 로고
    • Minireview: development and differentiation of gut endocrine cells
    • Schonhoff S.E., et al. Minireview: development and differentiation of gut endocrine cells. Endocrinology 2004, 145:2639-2644.
    • (2004) Endocrinology , vol.145 , pp. 2639-2644
    • Schonhoff, S.E.1
  • 58
    • 84855697236 scopus 로고    scopus 로고
    • Innate dysfunction promotes linear growth failure in pediatric Crohn's disease and growth hormone resistance in murine ileitis
    • D'Mello S., et al. Innate dysfunction promotes linear growth failure in pediatric Crohn's disease and growth hormone resistance in murine ileitis. Inflamm. Bowel Dis. 2012, 18:236-245.
    • (2012) Inflamm. Bowel Dis. , vol.18 , pp. 236-245
    • D'Mello, S.1
  • 59
    • 84926434309 scopus 로고    scopus 로고
    • An EphB-Abl signaling pathway is associated with intestinal tumor initiation and growth
    • 281ra244
    • Kundu P., et al. An EphB-Abl signaling pathway is associated with intestinal tumor initiation and growth. Sci. Transl. Med. 2015, 7:281ra244.
    • (2015) Sci. Transl. Med. , vol.7
    • Kundu, P.1
  • 60
    • 79955681163 scopus 로고    scopus 로고
    • The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse
    • Merlos-Suarez A., et al. The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse. Cell Stem Cell 2011, 8:511-524.
    • (2011) Cell Stem Cell , vol.8 , pp. 511-524
    • Merlos-Suarez, A.1
  • 61
    • 84936874106 scopus 로고    scopus 로고
    • Circulating hematopoietic stem cells and putative intestinal stem cells in coeliac disease
    • Piscaglia A.C., et al. Circulating hematopoietic stem cells and putative intestinal stem cells in coeliac disease. J. Transl. Med. 2015, 13:220.
    • (2015) J. Transl. Med. , vol.13 , pp. 220
    • Piscaglia, A.C.1
  • 62
    • 84960193503 scopus 로고    scopus 로고
    • High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
    • Beyaz S., et al. High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature 2016, 531:53-58.
    • (2016) Nature , vol.531 , pp. 53-58
    • Beyaz, S.1
  • 63
    • 84862994618 scopus 로고    scopus 로고
    • MTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake
    • Yilmaz O.H., et al. mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake. Nature 2012, 486:490-495.
    • (2012) Nature , vol.486 , pp. 490-495
    • Yilmaz, O.H.1
  • 64
    • 0037467798 scopus 로고    scopus 로고
    • Tissue-engineered neomucosa: morphology, enterocyte dynamics, and SGLT1 expression topography
    • Tavakkolizadeh A., et al. Tissue-engineered neomucosa: morphology, enterocyte dynamics, and SGLT1 expression topography. Transplantation 2003, 75:181-185.
    • (2003) Transplantation , vol.75 , pp. 181-185
    • Tavakkolizadeh, A.1
  • 65
    • 33747377731 scopus 로고    scopus 로고
    • Orthotopic transplantation of intestinal mucosal organoids in rodents
    • Avansino J.R., et al. Orthotopic transplantation of intestinal mucosal organoids in rodents. Surgery 2006, 140:423-434.
    • (2006) Surgery , vol.140 , pp. 423-434
    • Avansino, J.R.1
  • 66
    • 84862777784 scopus 로고    scopus 로고
    • + stem cell
    • + stem cell. Nat. Med. 2012, 18:618-623.
    • (2012) Nat. Med. , vol.18 , pp. 618-623
    • Yui, S.1
  • 67
    • 84964313624 scopus 로고    scopus 로고
    • An in vivo model of human small intestine using pluripotent stem cells
    • Watson C.L., et al. An in vivo model of human small intestine using pluripotent stem cells. Nat. Med. 2014, 20:1310-1314.
    • (2014) Nat. Med. , vol.20 , pp. 1310-1314
    • Watson, C.L.1
  • 68
    • 84878760040 scopus 로고    scopus 로고
    • Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications
    • Sato T., Clevers H. Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 2013, 340:1190-1194.
    • (2013) Science , vol.340 , pp. 1190-1194
    • Sato, T.1    Clevers, H.2
  • 69
    • 80054857419 scopus 로고    scopus 로고
    • Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium
    • Sato T., et al. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. Gastroenterology 2011, 141:1762-1772.
    • (2011) Gastroenterology , vol.141 , pp. 1762-1772
    • Sato, T.1
  • 70
    • 84880292828 scopus 로고    scopus 로고
    • A functional CFTR assay using primary cystic fibrosis intestinal organoids
    • Dekkers J.F., et al. A functional CFTR assay using primary cystic fibrosis intestinal organoids. Nat. Med. 2013, 19:939-945.
    • (2013) Nat. Med. , vol.19 , pp. 939-945
    • Dekkers, J.F.1
  • 71
    • 84902957441 scopus 로고    scopus 로고
    • Loss of syntaxin 3 causes variant microvillus inclusion disease
    • Wiegerinck C.L., et al. Loss of syntaxin 3 causes variant microvillus inclusion disease. Gastroenterology 2014, 147:65-68.
    • (2014) Gastroenterology , vol.147 , pp. 65-68
    • Wiegerinck, C.L.1
  • 72
    • 84939524213 scopus 로고    scopus 로고
    • Perspectives for regenerative medicine in the treatment of inflammatory bowel diseases
    • Okamoto R., Watanabe M. Perspectives for regenerative medicine in the treatment of inflammatory bowel diseases. Digestion 2015, 92:73-77.
    • (2015) Digestion , vol.92 , pp. 73-77
    • Okamoto, R.1    Watanabe, M.2
  • 73
    • 84964317107 scopus 로고    scopus 로고
    • Organoid models of human gastrointestinal development and disease
    • Dedhia P.H., et al. Organoid models of human gastrointestinal development and disease. Gastroenterology 2016, 150:1098-1112.
    • (2016) Gastroenterology , vol.150 , pp. 1098-1112
    • Dedhia, P.H.1
  • 74
    • 84939251707 scopus 로고    scopus 로고
    • Colorectal cancer-derived tumor spheroids retain the characteristics of original tumors
    • Lee S.H., et al. Colorectal cancer-derived tumor spheroids retain the characteristics of original tumors. Cancer Lett. 2015, 367:34-42.
    • (2015) Cancer Lett. , vol.367 , pp. 34-42
    • Lee, S.H.1
  • 75
    • 84922875352 scopus 로고    scopus 로고
    • In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection
    • Bartfeld S., et al. In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection. Gastroenterology 2015, 148:126-136.
    • (2015) Gastroenterology , vol.148 , pp. 126-136
    • Bartfeld, S.1
  • 76
    • 85009424076 scopus 로고    scopus 로고
    • Salmonella-infected crypt-derived intestinal organoid culture system for host-bacterial interactions
    • Zhang Y.G., et al. Salmonella-infected crypt-derived intestinal organoid culture system for host-bacterial interactions. Physiol. Rep. 2014, 2:e12147.
    • (2014) Physiol. Rep. , vol.2
    • Zhang, Y.G.1
  • 77
    • 84904051527 scopus 로고    scopus 로고
    • Ex vivo culture of the intestinal epithelium: strategies and applications
    • Leushacke M., Barker N. Ex vivo culture of the intestinal epithelium: strategies and applications. Gut 2014, 63:1345-1354.
    • (2014) Gut , vol.63 , pp. 1345-1354
    • Leushacke, M.1    Barker, N.2
  • 78
    • 77955765039 scopus 로고    scopus 로고
    • The pancreas allograft donor: current status, controversies, and challenges for the future
    • Fridell J.A., et al. The pancreas allograft donor: current status, controversies, and challenges for the future. Clin. Transplant. 2010, 24:433-449.
    • (2010) Clin. Transplant. , vol.24 , pp. 433-449
    • Fridell, J.A.1
  • 79
    • 84937519203 scopus 로고    scopus 로고
    • Increasing the number of organ transplants in the United States by optimizing donor authorization rates
    • Goldberg D.S., et al. Increasing the number of organ transplants in the United States by optimizing donor authorization rates. Am. J. Transplant. 2015, 15:2117-2125.
    • (2015) Am. J. Transplant. , vol.15 , pp. 2117-2125
    • Goldberg, D.S.1
  • 80
    • 84876666830 scopus 로고    scopus 로고
    • Combined pancreas-kidney transplantation for patients with end-stage nephropathy caused by type-2 diabetes mellitus
    • Margreiter C., et al. Combined pancreas-kidney transplantation for patients with end-stage nephropathy caused by type-2 diabetes mellitus. Transplantation 2013, 95:1030-1036.
    • (2013) Transplantation , vol.95 , pp. 1030-1036
    • Margreiter, C.1
  • 81
    • 84906674143 scopus 로고    scopus 로고
    • Autologous nonmyeloablative hematopoietic stem cell transplantation in new-onset type 1 diabetes: a multicenter analysis
    • D'Addio F., et al. Autologous nonmyeloablative hematopoietic stem cell transplantation in new-onset type 1 diabetes: a multicenter analysis. Diabetes 2014, 63:3041-3046.
    • (2014) Diabetes , vol.63 , pp. 3041-3046
    • D'Addio, F.1
  • 82
    • 0031587697 scopus 로고    scopus 로고
    • Seminars in medicine of the Beth Israel Deaconess Medical Center. Insulin-like growth factors
    • Le Roith D. Seminars in medicine of the Beth Israel Deaconess Medical Center. Insulin-like growth factors. N. Engl. J. Med. 1997, 336:633-640.
    • (1997) N. Engl. J. Med. , vol.336 , pp. 633-640
    • Le Roith, D.1
  • 83
    • 0028148339 scopus 로고
    • Prevalence of gastrointestinal symptoms in diabetic patients and non-diabetic subjects
    • Enck P., et al. Prevalence of gastrointestinal symptoms in diabetic patients and non-diabetic subjects. Z. Gastroenterol. 1994, 32:637-641.
    • (1994) Z. Gastroenterol. , vol.32 , pp. 637-641
    • Enck, P.1
  • 84
    • 80051507729 scopus 로고    scopus 로고
    • From intestinal stem cells to inflammatory bowel diseases
    • Gersemann M., et al. From intestinal stem cells to inflammatory bowel diseases. World J. Gastroenterol. 2011, 17:3198-3203.
    • (2011) World J. Gastroenterol. , vol.17 , pp. 3198-3203
    • Gersemann, M.1
  • 85
    • 84955609854 scopus 로고    scopus 로고
    • Celiac disease histopathology recapitulates hedgehog downregulation, consistent with wound healing processes activation
    • Senger S., et al. Celiac disease histopathology recapitulates hedgehog downregulation, consistent with wound healing processes activation. PLoS ONE 2015, 10:e0144634.
    • (2015) PLoS ONE , vol.10
    • Senger, S.1
  • 86
    • 45549085634 scopus 로고    scopus 로고
    • Human colon cancer stem cells: a new paradigm in gastrointestinal oncology
    • Boman B.M., Huang E. Human colon cancer stem cells: a new paradigm in gastrointestinal oncology. J. Clin. Oncol. 2008, 26:2828-2838.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 2828-2838
    • Boman, B.M.1    Huang, E.2
  • 87
    • 0348053694 scopus 로고    scopus 로고
    • Biomechanical and morphometric intestinal remodelling during experimental diabetes in rats
    • Zhao J., et al. Biomechanical and morphometric intestinal remodelling during experimental diabetes in rats. Diabetologia 2003, 46:1688-1697.
    • (2003) Diabetologia , vol.46 , pp. 1688-1697
    • Zhao, J.1
  • 88
    • 77953302950 scopus 로고    scopus 로고
    • Inflammatory tendencies and overproduction of IL-17 in the colon of young NOD mice are counteracted with diet change
    • Alam C., et al. Inflammatory tendencies and overproduction of IL-17 in the colon of young NOD mice are counteracted with diet change. Diabetes 2010, 59:2237-2246.
    • (2010) Diabetes , vol.59 , pp. 2237-2246
    • Alam, C.1
  • 89
    • 4644329209 scopus 로고    scopus 로고
    • Enteropathy precedes type 1 diabetes in the BB rat
    • Graham S., et al. Enteropathy precedes type 1 diabetes in the BB rat. Gut 2004, 53:1437-1444.
    • (2004) Gut , vol.53 , pp. 1437-1444
    • Graham, S.1
  • 90
    • 11144353743 scopus 로고    scopus 로고
    • Ultrastructural mucosal alterations and increased intestinal permeability in non-celiac, type I diabetic patients
    • Secondulfo M., et al. Ultrastructural mucosal alterations and increased intestinal permeability in non-celiac, type I diabetic patients. Dig. Liver Dis. 2004, 36:35-45.
    • (2004) Dig. Liver Dis. , vol.36 , pp. 35-45
    • Secondulfo, M.1


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