-
1
-
-
58149091806
-
The "perfect storm" for type 1 diabetes: The complex interplay between intestinal microbiota, gut permeability, and mucosal immunity
-
18820210 10.2337/db08-0331 1:CAS:528:DC%2BD1MXhs1KnsL0%3D
-
Vaarala O, Atkinson MA, Neu J. The "perfect storm" for type 1 diabetes: the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity. Diabetes. 2008;57:2555-62.
-
(2008)
Diabetes
, vol.57
, pp. 2555-2562
-
-
Vaarala, O.1
Atkinson, M.A.2
Neu, J.3
-
2
-
-
33750906233
-
Increased intestinal permeability precedes clinical onset of type 1 diabetes
-
17028899 10.1007/s00125-006-0465-3 1:STN:280:DC%2BD28nmtV2qtg%3D%3D
-
Bosi E, Molteni L, Radaelli MG, Folini L, Fermo I, Bazzigaluppi E, et al. Increased intestinal permeability precedes clinical onset of type 1 diabetes. Diabetologia. 2006;49:2824-7.
-
(2006)
Diabetologia
, vol.49
, pp. 2824-2827
-
-
Bosi, E.1
Molteni, L.2
Radaelli, M.G.3
Folini, L.4
Fermo, I.5
Bazzigaluppi, E.6
-
3
-
-
55749100160
-
Leaking gut in type 1 diabetes
-
19122519 10.1097/MOG.0b013e32830e6d98
-
Vaarala O. Leaking gut in type 1 diabetes. Curr Opin Gastroenterol. 2008;24:701-6.
-
(2008)
Curr Opin Gastroenterol
, vol.24
, pp. 701-706
-
-
Vaarala, O.1
-
4
-
-
0041820123
-
Immunologic activity in the small intestinal mucosa of pediatric patients with type 1 diabetes
-
12941768 10.2337/diabetes.52.9.2287 1:CAS:528:DC%2BD3sXntFeqtbg%3D
-
Westerholm-Ormio M, Vaarala O, Pihkala P, Ilonen J, Savilahti E. Immunologic activity in the small intestinal mucosa of pediatric patients with type 1 diabetes. Diabetes. 2003;52:2287-95.
-
(2003)
Diabetes
, vol.52
, pp. 2287-2295
-
-
Westerholm-Ormio, M.1
Vaarala, O.2
Pihkala, P.3
Ilonen, J.4
Savilahti, E.5
-
5
-
-
3042819239
-
In vitro-deranged intestinal immune response to gliadin in type 1 diabetes
-
15220190 10.2337/diabetes.53.7.1680 1:CAS:528:DC%2BD2cXlslWgt74%3D
-
Auricchio R, Paparo F, Maglio M, Franzese A, Lombardi F, Valerio G, et al. In vitro-deranged intestinal immune response to gliadin in type 1 diabetes. Diabetes. 2004;53:1680-3.
-
(2004)
Diabetes
, vol.53
, pp. 1680-1683
-
-
Auricchio, R.1
Paparo, F.2
Maglio, M.3
Franzese, A.4
Lombardi, F.5
Valerio, G.6
-
6
-
-
43349106670
-
Infiltration of forkhead box P3-expressing cells in small intestinal mucosa in coeliac disease but not in type 1 diabetes
-
18435801 10.1111/j.1365-2249.2008.03662.x 1:STN:280: DC%2BD1czgtValtA%3D%3D
-
Tiittanen M, Westerholm-Ormio M, Verkasalo M, Savilahti E, Vaarala O. Infiltration of forkhead box P3-expressing cells in small intestinal mucosa in coeliac disease but not in type 1 diabetes. Clin Exp Immunol. 2008;152:498-507.
-
(2008)
Clin Exp Immunol
, vol.152
, pp. 498-507
-
-
Tiittanen, M.1
Westerholm-Ormio, M.2
Verkasalo, M.3
Savilahti, E.4
Vaarala, O.5
-
7
-
-
80052829380
-
Defective differentiation of regulatory FoxP3+ T cells by small-intestinal dendritic cells in patients with type 1 diabetes
-
21646390 10.2337/db10-1201 1:CAS:528:DC%2BC3MXhtValurbJ
-
Badami E, Sorini C, Coccia M, Usuelli V, Molteni L, Bolla AM, et al. Defective differentiation of regulatory FoxP3+ T cells by small-intestinal dendritic cells in patients with type 1 diabetes. Diabetes. 2011;60:2120-4.
-
(2011)
Diabetes
, vol.60
, pp. 2120-2124
-
-
Badami, E.1
Sorini, C.2
Coccia, M.3
Usuelli, V.4
Molteni, L.5
Bolla, A.M.6
-
8
-
-
52649144787
-
Enhanced levels of cow's milk antibodies in infancy in children who develop type 1 diabetes later in childhood
-
18503496 10.1111/j.1399-5448.2008.00413.x
-
Luopajärvi K, Savilahti E, Virtanen SM, Ilonen J, Knip M, Akerblom HK, et al. Enhanced levels of cow's milk antibodies in infancy in children who develop type 1 diabetes later in childhood. Pediatr Diabetes. 2008;9:434-41.
-
(2008)
Pediatr Diabetes.
, vol.9
, pp. 434-441
-
-
Luopajärvi, K.1
Savilahti, E.2
Virtanen, S.M.3
Ilonen, J.4
Knip, M.5
Akerblom, H.K.6
-
9
-
-
78650616947
-
Toward defining the autoimmune microbiome for type 1 diabetes
-
20613793 10.1038/ismej.2010.92 1:CAS:528:DC%2BC3cXhsFylur3P The findings of this pilot study including 4 healthy individuals and 4 children who developed type 1 diabetes suggest type 1 diabetes associated differences in the intestinal microbiota
-
•• Giongo A, Gano KA, Crabb DB, Mukherjee N, Novelo LL, Casella G, et al. Toward defining the autoimmune microbiome for type 1 diabetes. ISME J. 2011;5:82-91. The findings of this pilot study including 4 healthy individuals and 4 children who developed type 1 diabetes suggest type 1 diabetes associated differences in the intestinal microbiota.
-
(2011)
ISME J
, vol.5
, pp. 82-91
-
-
Giongo, A.1
Gano, K.A.2
Crabb, D.B.3
Mukherjee, N.4
Novelo, L.L.5
Casella, G.6
-
10
-
-
80054722148
-
Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes
-
10.1371/journal.pone.0025792 The findings of this pilot study including 4 healthy individuals and 4 children who developed type 1 diabetes suggest that alterations in the metabolic potential of the microbiota is seen in type 1 diabetes
-
•• Brown CT, Davis-Richardson AG, Giongo A, Gano KA, Crabb DB, Mukherjee N, et al. Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes. PLoS One. 2011;610:e25792. The findings of this pilot study including 4 healthy individuals and 4 children who developed type 1 diabetes suggest that alterations in the metabolic potential of the microbiota is seen in type 1 diabetes.
-
(2011)
PLoS One
, vol.610
, pp. 25792
-
-
Brown, C.T.1
Davis-Richardson, A.G.2
Giongo, A.3
Gano, K.A.4
Crabb, D.B.5
Mukherjee, N.6
-
11
-
-
84872592295
-
Fecal microbiota composition differs between children with beta-cell autoimmunity and those without
-
23274889 10.2337/db12-0526 This study demonstrates low abundance of butyrate producing bacteria and increased abundance of Bacteroides in prediabetic individuals providing a link to dysregulation of gut immune system and altered microbiota in type 1 diabetes
-
•• Goffau M, Luopajärvi K, Knip M, Ilonen J, Ruohtula T, Härkönen T, et al. Fecal microbiota composition differs between children with beta-cell autoimmunity and those without. Diabetes. 2013;62:1238-44. This study demonstrates low abundance of butyrate producing bacteria and increased abundance of Bacteroides in prediabetic individuals providing a link to dysregulation of gut immune system and altered microbiota in type 1 diabetes.
-
(2013)
Diabetes
, vol.62
, pp. 1238-1244
-
-
Goffau, M.1
Luopajärvi, K.2
Knip, M.3
Ilonen, J.4
Ruohtula, T.5
Härkönen, T.6
-
12
-
-
77954738601
-
Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
-
20566854 10.1073/pnas.0909122107 1:CAS:528:DC%2BC3cXovFyit7s%3D This study describes Bacteroides fragilis and its polysaccharide A as inducer of intestinal regulatory T-cell development and regulator of colitis
-
• Round JL, Mazmanian SK. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc Natl Acad Sci U S A. 2010;107:12204-9. This study describes Bacteroides fragilis and its polysaccharide A as inducer of intestinal regulatory T-cell development and regulator of colitis.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 12204-12209
-
-
Round, J.L.1
Mazmanian, S.K.2
-
13
-
-
77958119730
-
Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression
-
20817872 10.4049/jimmunol.1001443 This article provides evidence of extra-intestinal immunological effects of commensals
-
• Ochoa-Repáraz J, Mielcarz DW, Ditrio LE, Burroughs AR, Begum-Haque S, Dasgupta S, et al. Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression. J Immunol. 2010;185:4101-8. This article provides evidence of extra-intestinal immunological effects of commensals.
-
(2010)
J Immunol
, vol.185
, pp. 4101-4108
-
-
Ochoa-Repáraz, J.1
Mielcarz, D.W.2
Ditrio, L.E.3
Burroughs, A.R.4
Begum-Haque, S.5
Dasgupta, S.6
-
14
-
-
85027947787
-
Induction of colonic regulatory T cells by indigenous Clostridium species
-
21205640 10.1126/science.1198469 1:CAS:528:DC%2BC3MXmsVCjsw%3D%3D This study demonstrates the induction of regulatory T-cells by Clostridium species and the long-lasting immunomodulatory effects of the oral administration with these Clostridium species at early life in a mouse model
-
• Atarashi K, Tanoue T, Shima T, Imaoka A, Kuwahara T, Momose Y, et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science. 2011;331:337-41. This study demonstrates the induction of regulatory T-cells by Clostridium species and the long-lasting immunomodulatory effects of the oral administration with these Clostridium species at early life in a mouse model.
-
(2011)
Science
, vol.331
, pp. 337-341
-
-
Atarashi, K.1
Tanoue, T.2
Shima, T.3
Imaoka, A.4
Kuwahara, T.5
Momose, Y.6
-
15
-
-
84865296650
-
The induction of Treg cells by gut-indigenous Clostridium
-
22673877 10.1016/j.coi.2012.05.007 1:CAS:528:DC%2BC38XotVOqsrk%3D
-
Nagano Y, Itoh K, Honda K. The induction of Treg cells by gut-indigenous Clostridium. Curr Opin Immunol. 2012;24:392-7.
-
(2012)
Curr Opin Immunol
, vol.24
, pp. 392-397
-
-
Nagano, Y.1
Itoh, K.2
Honda, K.3
-
16
-
-
70350343544
-
Induction of intestinal Th17 cells by segmented filamentous bacteria
-
19836068 10.1016/j.cell.2009.09.033 1:CAS:528:DC%2BD1MXhsFKltL%2FL
-
Ivanov II, Atarashi K, Manel N, Brodie EL, Shima T, Karaoz U, et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell. 2009;139:485-98.
-
(2009)
Cell
, vol.139
, pp. 485-498
-
-
Ivanov, I.I.1
Atarashi, K.2
Manel, N.3
Brodie, E.L.4
Shima, T.5
Karaoz, U.6
-
17
-
-
77956409750
-
Inhibition of type 1 diabetes correlated to a Lactobacillus johnsonii N6.2-mediated Th17 bias
-
10.1371/journal.pone.0010507 20463897 10.1371/journal.pone.0010507 This study identifies Lactobacillus johnsonii as an up-regulator of the intestinal IL-17 expression
-
• Valladares R, Sankar D, Li N, Williams E, Lai KK, Abdelgeliel AS, et al. Inhibition of type 1 diabetes correlated to a Lactobacillus johnsonii N6.2-mediated Th17 bias. PLoS One. 2010;5:e10507. doi: 10.1371/journal.pone. 0010507. This study identifies Lactobacillus johnsonii as an up-regulator of the intestinal IL-17 expression.
-
(2010)
PLoS One
, vol.5
, pp. 10507
-
-
Valladares, R.1
Sankar, D.2
Li, N.3
Williams, E.4
Lai, K.K.5
Abdelgeliel, A.S.6
-
18
-
-
78149475225
-
Dietary intervention in infancy and later signs of beta-cell autoimmunity
-
21067382 10.1056/NEJMoa1004809 1:CAS:528:DC%2BC3cXhsVCht77I
-
Knip M, Virtanen SM, Seppä K, Ilonen J, Savilahti E, Vaarala O, et al. Dietary intervention in infancy and later signs of beta-cell autoimmunity. N Engl J Med. 2010;363:1900-8.
-
(2010)
N Engl J Med
, vol.363
, pp. 1900-1908
-
-
Knip, M.1
Virtanen, S.M.2
Seppä, K.3
Ilonen, J.4
Savilahti, E.5
Vaarala, O.6
-
19
-
-
84863554905
-
Removal of bovine insulin from cow's milk formula and early initiation of beta-cell autoimmunity in the FINDIA Pilot Study
-
22393174 10.1001/archpediatrics.2011.1559
-
Vaarala O, Ilonen J, Ruohtula T, Pesola J, Virtanen SM, Härkönen T, et al. Removal of bovine insulin from cow's milk formula and early initiation of beta-cell autoimmunity in the FINDIA Pilot Study. Arch Pediatr Adolesc Med. 2012;166:608-14.
-
(2012)
Arch Pediatr Adolesc Med.
, vol.166
, pp. 608-614
-
-
Vaarala, O.1
Ilonen, J.2
Ruohtula, T.3
Pesola, J.4
Virtanen, S.M.5
Härkönen, T.6
-
20
-
-
84862276328
-
Structure, function, and diversity of the healthy human microbiome
-
Human Microbiome Project Consortium 10.1038/nature11234 The extensive analyses of our microbiome indicate that the composition of gut microbiota also shows significant variation between healthy individuals
-
• Human Microbiome Project Consortium. Structure, function, and diversity of the healthy human microbiome. Nature. 2012;486:207-14. The extensive analyses of our microbiome indicate that the composition of gut microbiota also shows significant variation between healthy individuals.
-
(2012)
Nature
, vol.486
, pp. 207-214
-
-
-
21
-
-
58749112734
-
A core gut microbiome in obese and lean twins
-
19043404 10.1038/nature07540 1:CAS:528:DC%2BD1MXotlOlsw%3D%3D
-
Turnbaugh PJ, Hamady M, Yatsunenko T, Cantarel BL, Duncan A, Ley RE, et al. A core gut microbiome in obese and lean twins. Nature. 2009;457:480-4.
-
(2009)
Nature
, vol.457
, pp. 480-484
-
-
Turnbaugh, P.J.1
Hamady, M.2
Yatsunenko, T.3
Cantarel, B.L.4
Duncan, A.5
Ley, R.E.6
-
22
-
-
30944466824
-
Reduced diversity of fecal microbiota in Crohn's disease revealed by a metagenomic approach
-
16188921 10.1136/gut.2005.073817 1:CAS:528:DC%2BD28XhsFaqsL8%3D
-
Manichanh C, Rigottier-Gois L, Bonnaud E, Gloux K, Pelletier E, Frangeul L, et al. Reduced diversity of fecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut. 2006;55:205-11.
-
(2006)
Gut
, vol.55
, pp. 205-211
-
-
Manichanh, C.1
Rigottier-Gois, L.2
Bonnaud, E.3
Gloux, K.4
Pelletier, E.5
Frangeul, L.6
-
23
-
-
38649115342
-
Microbial influences in inflammatory bowel diseases
-
18242222 10.1053/j.gastro.2007.11.059 1:CAS:528:DC%2BD1cXivFOjs7o%3D
-
Sartor RB. Microbial influences in inflammatory bowel diseases. Gastroenterology. 2008;134:577-94.
-
(2008)
Gastroenterology
, vol.134
, pp. 577-594
-
-
Sartor, R.B.1
-
24
-
-
38949084200
-
Does the intestinal bifidobacterial colonisation affect bacterial translocation?
-
17988900 10.1016/j.anaerobe.2007.09.003 1:CAS:528:DC%2BD1cXitVenurw%3D
-
Romond MB, Colavizza M, Mullié C, Kalach N, Kremp O, Mielcarek C, et al. Does the intestinal bifidobacterial colonisation affect bacterial translocation? Anaerobe. 2008;14:43-8.
-
(2008)
Anaerobe
, vol.14
, pp. 43-48
-
-
Romond, M.B.1
Colavizza, M.2
Mullié, C.3
Kalach, N.4
Kremp, O.5
Mielcarek, C.6
-
25
-
-
33746750046
-
Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes?
-
16816951 10.1007/s00125-006-0334-0 1:CAS:528:DC%2BD28XnslSitb8%3D
-
Brugman S, Klatter FA, Visser JT, et al. Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes? Diabetologia. 2006;49:2105-8.
-
(2006)
Diabetologia
, vol.49
, pp. 2105-2108
-
-
Brugman, S.1
Klatter, F.A.2
Visser, J.T.3
-
26
-
-
67349112373
-
Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model
-
19225551 10.1038/ismej.2009.5 1:CAS:528:DC%2BD1MXms12iu7o%3D
-
Roesch LF, Lorca GL, Casella G, et al. Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model. ISME J. 2009;3:536-48.
-
(2009)
ISME J
, vol.3
, pp. 536-548
-
-
Roesch, L.F.1
Lorca, G.L.2
Casella, G.3
-
27
-
-
84874357602
-
Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity
-
23328391 10.1126/science.1233521 1:CAS:528:DC%2BC3sXjtVGjsbk%3D This study indicates that sex hormones modulate gut microbiota and vice versa and provides a novel link to hormone-dependent regulation of autoimmune diseases
-
• Markle JG, Frank DN, Mortin-Toth S, Robertson CE, Feazel LM, Rolle-Kampczyk U, et al. Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity. Science. 2013;339:1084-8. This study indicates that sex hormones modulate gut microbiota and vice versa and provides a novel link to hormone-dependent regulation of autoimmune diseases.
-
(2013)
Science
, vol.339
, pp. 1084-1088
-
-
Markle, J.G.1
Frank, D.N.2
Mortin-Toth, S.3
Robertson, C.E.4
Feazel, L.M.5
Rolle-Kampczyk, U.6
-
28
-
-
0030279219
-
The role of butyrate in human colonic epithelial cells: An energy source or inducer of differentiation and apoptosis?
-
9004335 10.1079/PNS19960090 1:CAS:528:DyaK2sXotlegtg%3D%3D
-
Hague A, Butt AJ, Paraskeva C. The role of butyrate in human colonic epithelial cells: an energy source or inducer of differentiation and apoptosis? Proc Nutr Soc. 1996;55:937-43.
-
(1996)
Proc Nutr Soc
, vol.55
, pp. 937-943
-
-
Hague, A.1
Butt, A.J.2
Paraskeva, C.3
-
29
-
-
69549114504
-
Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers
-
19625695 10.3945/jn.109.104638 1:CAS:528:DC%2BD1MXhtlWrt7nM
-
Peng L, Li ZR, Green RS, Holzman IR, Lin J. Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers. J Nutr. 2009;139:1619-25.
-
(2009)
J Nutr
, vol.139
, pp. 1619-1625
-
-
Peng, L.1
Li, Z.R.2
Green, R.S.3
Holzman, I.R.4
Lin, J.5
-
30
-
-
78449254492
-
Butyrate and type 1 diabetes mellitus: Can we fix the intestinal leak?
-
20706153 10.1097/MPG.0b013e3181dd913a 1:CAS:528:DC%2BC3cXht1WjtLfK
-
Li N, Hatch M, Wasserfall CH, Douglas-Escobar M, Atkinson MA, Schatz DA, et al. Butyrate and type 1 diabetes mellitus: can we fix the intestinal leak? J Pediatr Gastroenterol Nutr. 2010;51:414-7.
-
(2010)
J Pediatr Gastroenterol Nutr
, vol.51
, pp. 414-417
-
-
Li, N.1
Hatch, M.2
Wasserfall, C.H.3
Douglas-Escobar, M.4
Atkinson, M.A.5
Schatz, D.A.6
-
31
-
-
0036793753
-
Acetate utilization and butyryl coenzyme A (CoA): Acetate-CoA transferase in butyrate-producing bacteria from the human large intestine
-
12324374 10.1128/AEM.68.10.5186-5190.2002 1:CAS:528:DC%2BD38XnvFCks7w%3D
-
Duncan SH, Barcenilla A, Stewart CS, Pryde SE, Flint HJ. Acetate utilization and butyryl coenzyme A (CoA):acetate-CoA transferase in butyrate-producing bacteria from the human large intestine. Appl Environ Microbiol. 2002;68:5186-90.
-
(2002)
Appl Environ Microbiol
, vol.68
, pp. 5186-5190
-
-
Duncan, S.H.1
Barcenilla, A.2
Stewart, C.S.3
Pryde, S.E.4
Flint, H.J.5
-
32
-
-
8144224956
-
Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product
-
15466518 10.1128/AEM.70.10.5810-5817.2004 1:CAS:528:DC%2BD2cXosl2itb8%3D
-
Duncan SH, Louis P, Flint HJ. Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product. Appl Environ Microbiol. 2004;70:5810-7.
-
(2004)
Appl Environ Microbiol
, vol.70
, pp. 5810-5817
-
-
Duncan, S.H.1
Louis, P.2
Flint, H.J.3
-
33
-
-
55949124035
-
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
-
18936492 10.1073/pnas.0804812105 1:CAS:528:DC%2BD1cXhtleks7%2FI
-
Sokol H, Pigneur B, Watterlot L, Lakhdari O, Bermidez-Humaran LG, Gratadoux JJ, et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A. 2008;105:16731-6.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16731-16736
-
-
Sokol, H.1
Pigneur, B.2
Watterlot, L.3
Lakhdari, O.4
Bermidez-Humaran, L.G.5
Gratadoux, J.J.6
-
34
-
-
84866386969
-
Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse
-
22572803 10.1007/s00125-012-2564-7 1:CAS:528:DC%2BC38XhtVWjt7%2FJ The findings of this study suggest that Akkermansia muciniphila could provide protection from autoimmune diabetes
-
Hansen CH, Krych L, Nielsen DS, Vogensen FK, Hansen LH, Sørensen SJ, et al. Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse. Diabetologia. 2012;55:2285-94. The findings of this study suggest that Akkermansia muciniphila could provide protection from autoimmune diabetes.
-
(2012)
Diabetologia
, vol.55
, pp. 2285-2294
-
-
Hansen, C.H.1
Krych, L.2
Nielsen, D.S.3
Vogensen, F.K.4
Hansen, L.H.5
Sørensen, S.J.6
-
35
-
-
84857404715
-
Type 1 diabetes is associated with enterovirus infection in gut mucosa
-
22315304 10.2337/db11-1157 1:CAS:528:DC%2BC38XovFegur0%3D
-
Oikarinen M, Tauriainen S, Oikarinen S, Honkanen T, Collin P, Rantala I, et al. Type 1 diabetes is associated with enterovirus infection in gut mucosa. Diabetes. 2012;61:687-91.
-
(2012)
Diabetes
, vol.61
, pp. 687-691
-
-
Oikarinen, M.1
Tauriainen, S.2
Oikarinen, S.3
Honkanen, T.4
Collin, P.5
Rantala, I.6
-
36
-
-
84867286012
-
Prevention of virus-induced type 1 diabetes with antibiotic therapy
-
22988033 10.4049/jimmunol.1201257 1:CAS:528:DC%2BC38XhsVKrtL3N This paper demonstrates that viral infection caused change in the composition of the intestinal bacteria is a key determinant in the development of "virus induced autoimmune diabetes"
-
• Hara N, Alkanani AK, Ir D, Robertson CE, Wagner BD, Frank DN, et al. Prevention of virus-induced type 1 diabetes with antibiotic therapy. J Immunol. 2012;189:3805-14. This paper demonstrates that viral infection caused change in the composition of the intestinal bacteria is a key determinant in the development of "virus induced autoimmune diabetes".
-
(2012)
J Immunol
, vol.189
, pp. 3805-3814
-
-
Hara, N.1
Alkanani, A.K.2
Ir, D.3
Robertson, C.E.4
Wagner, B.D.5
Frank, D.N.6
-
37
-
-
77953904042
-
Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine
-
20602997 10.1016/j.cell.2010.05.009 1:CAS:528:DC%2BC3cXovFartbo%3D The development of Crohn's disease resembling pathologies was demonstrated in a mouse model, in which toxin induced intestinal changes were dependent on the interaction of the disease related gene polymorphism, norovirus infection, commensal bacteria and activation of IFN-γ
-
•• Cadwell K, Patel KK, Maloney NS, Liu T-C, NG ACY, Storer CE, et al. Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine. Cell. 2010;141:1135-45. The development of Crohn's disease resembling pathologies was demonstrated in a mouse model, in which toxin induced intestinal changes were dependent on the interaction of the disease related gene polymorphism, norovirus infection, commensal bacteria and activation of IFN-γ.
-
(2010)
Cell
, vol.141
, pp. 1135-1145
-
-
Cadwell, K.1
Patel, K.K.2
Maloney, N.S.3
Liu, T.-C.4
Ng, A.C.Y.5
Storer, C.E.6
-
38
-
-
84865801888
-
Potential mechanisms explaining why hydrolyzed casein-based diets outclass single amino acid-based diets in the prevention of autoimmune diabetes in diabetes-prone BB rats
-
22539454 10.1002/dmrr.2311 1:CAS:528:DC%2BC38Xht1ymt73O
-
Visser JT, Bos NA, Harthoorn LF, Stellaard F, Beijer-Liefers S, Rozing J, et al. Potential mechanisms explaining why hydrolyzed casein-based diets outclass single amino acid-based diets in the prevention of autoimmune diabetes in diabetes-prone BB rats. Diabetes Metab Res Rev. 2012;28:505-13.
-
(2012)
Diabetes Metab Res Rev.
, vol.28
, pp. 505-513
-
-
Visser, J.T.1
Bos, N.A.2
Harthoorn, L.F.3
Stellaard, F.4
Beijer-Liefers, S.5
Rozing, J.6
-
39
-
-
0035908768
-
Bacteriotherapy: The time has come
-
11509411 10.1136/bmj.323.7309.353 1:STN:280:DC%2BD3MvmsVegtw%3D%3D
-
Huovinen P. Bacteriotherapy: the time has come. BMJ. 2001;323:353-4.
-
(2001)
BMJ
, vol.323
, pp. 353-354
-
-
Huovinen, P.1
|