An EphB-Abl signaling pathway is associated with intestinal tumor initiation and growth

Science Translational Medicine

Volumn 7, Issue 281, 2015, Pages

  Kundu, Parag ^a,b   Genander, Maria ^a   Strååt, Klas ^a   Classon, Johanna ^a   Ridgway, Rachel A ^c   Tan, Ee Hong ^c   Björk, Jan ^a   Martling, Anna ^a   Van Es, Johan ^d   Sansom, Owen J ^c   Clevers, Hans ^d   Pettersson, Sven ^a,b,e   Frisén, Jonas ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; EPHRIN B; IMATINIB; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; EPHRIN B2; TUMOR SUPPRESSOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; GROWTH RATE; IN VITRO STUDY; INTESTINE TUMOR; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR GROWTH; ADENOMA; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; LONGEVITY; METABOLISM; PATHOLOGY; TUMOR SUPPRESSOR GENE;

ADENOMA; ANIMALS; CARCINOGENESIS; CELL PROLIFERATION; EPHRIN-B2; GENES, APC; IMATINIB MESYLATE; INTESTINAL NEOPLASMS; LONGEVITY; MICE; PROTO-ONCOGENE PROTEINS C-ABL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84926434309     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3010567     Document Type: Article

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