Colorectal cancer-derived tumor spheroids retain the characteristics of original tumors

Cancer Letters

Volumn 367, Issue 1, 2015, Pages 34-42

  Lee, Sun Hwa ^a   Hong, Jun Hwa ^b,c   Park, Hwan Ki ^b   Park, Jun Seok ^b   Kim, Bo Kyung ^b   Lee, Jung Yi ^b   Jeong, Ji Yun ^c   Yoon, Ghil Suk ^c   Inoue, Masahiro ^d   Choi, Gyu Seog ^b   Lee, In Kyu ^b,c  

^a Daegu Gyeongbuk Medical Innovation Foundation   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

^c Kyungpook National University School of Medicine   (South Korea)

^d OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

Author keywords

Colorectal cancer; Spheroid cultures; Xenograft

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 1; CD133 ANTIGEN; CD24 ANTIGEN; CETUXIMAB; EPITHELIAL CELL ADHESION MOLECULE; G PROTEIN COUPLED RECEPTOR; HERMES ANTIGEN; LGR5 PROTEIN; PROTEIN KINASE LKB1; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY; PROTEIN KINASE INHIBITOR; TUMOR MARKER;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APC GENE; ARTICLE; CANCER RESISTANCE; CANCER STEM CELL; CASE REPORT; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; DNA FINGERPRINTING; DRUG SENSITIVITY; FEMALE; GENE MUTATION; GENOTYPE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LKB1 GENE; MALE; MIDDLE AGED; MLH1 GENE; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; ONCOGENE K RAS; PRIORITY JOURNAL; SHORT TANDEM REPEAT; TUMOR SPHEROID; TUMOR SUPPRESSOR GENE; TUMOR XENOGRAFT; VERY ELDERLY; ANIMAL; BAGG ALBINO MOUSE; CANCER TRANSPLANTATION; CELL PROLIFERATION; COLORECTAL TUMOR; DOSE RESPONSE; DRUG EFFECTS; DRUG RESISTANCE; GENETICS; METABOLISM; MULTICELLULAR SPHEROID; MUTATION; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PATHOLOGY; SOUTH KOREA; TIME; TUMOR CELL CULTURE; TUMOR CELL LINE; TUMOR VOLUME; XENOGRAFT;

AGED; AGED, 80 AND OVER; ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DNA FINGERPRINTING; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, NEOPLASM; FEMALE; HETEROGRAFTS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE, INBRED BALB C; MICE, NUDE; MIDDLE AGED; MUTATION; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; PROTEIN KINASE INHIBITORS; REPUBLIC OF KOREA; SPHEROIDS, CELLULAR; TIME FACTORS; TUMOR BURDEN; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 84939251707     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2015.06.024     Document Type: Article

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