GDNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathway

Journal of Clinical Investigation

Volumn 116, Issue 2, 2006, Pages 344-356

  Anitha, Mallappa ^a   Gondha, Chetan ^a   Sutliff, Roy ^a   Parsadanian, Alexander ^b   Mwangi, Simon ^a   Sitaraman, Shanthi V ^a   Srinivasan, Shanthi ^a  

^a EMORY UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; STREPTOZOCIN; TRANSCRIPTION FACTOR FKHRL1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL LINE; CELL SURVIVAL; COMPARATIVE STUDY; CONTROLLED STUDY; DIABETIC NEUROPATHY; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXPOSURE; GLIA; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; NERVE CELL; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; STAINING; STOMACH EMPTYING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; DIABETES MELLITUS; DIABETIC NEUROPATHIES; ENTERIC NERVOUS SYSTEM; ENZYME ACTIVATION; FORKHEAD TRANSCRIPTION FACTORS; GASTROINTESTINAL DISEASES; GASTROINTESTINAL TRACT; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GLUCOSE; HUMANS; HYPERGLYCEMIA; MICE; NEURONS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT FUSION PROTEINS;

EID: 32444450603     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI26295     Document Type: Article

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