-
1
-
-
24044479679
-
BACE1 cytoplasmic domain interacts with the copper chaperone for superoxide dismutase-1 and binds copper
-
Angeletti, B., Waldron, K. J., Freeman, K. B., Bawagan, H., Hussain, I., Miller, C. C., Lau, K. F., Tennant, M. E., Dennison, C., Robinson, N. J. et al. (2005). BACE1 cytoplasmic domain interacts with the copper chaperone for superoxide dismutase-1 and binds copper. J. Biol. Chem. 280, 17930-17937.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17930-17937
-
-
Angeletti, B.1
Waldron, K.J.2
Freeman, K.B.3
Bawagan, H.4
Hussain, I.5
Miller, C.C.6
Lau, K.F.7
Tennant, M.E.8
Dennison, C.9
Robinson, N.J.10
-
2
-
-
1542782550
-
Novel cadherin-related membrane proteins, alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism
-
Araki, Y., Tomita, S., Yamaguchi, H., Miyagi, N., Sumioka, A., Kirino, Y. and Suzuki, T. (2003). Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism. J. Biol. Chem. 278, 49448-49458.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 49448-49458
-
-
Araki, Y.1
Tomita, S.2
Yamaguchi, H.3
Miyagi, N.4
Sumioka, A.5
Kirino, Y.6
Suzuki, T.7
-
3
-
-
33947607769
-
The novel cargo alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport
-
Araki, Y., Kawano, T., Taru, H., Saito, Y., Wada, S., Miyamoto, K., Kobayashi, H., Ishikawa, H. O., Ohsugi, Y., Yamamoto, T. et al. (2007). The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. EMBO J. 26, 1475-1486.
-
(2007)
EMBO J.
, vol.26
, pp. 1475-1486
-
-
Araki, Y.1
Kawano, T.2
Taru, H.3
Saito, Y.4
Wada, S.5
Miyamoto, K.6
Kobayashi, H.7
Ishikawa, H.O.8
Ohsugi, Y.9
Yamamoto, T.10
-
4
-
-
34548301693
-
Beta-amyloid precursor protein can be transported independent of any sorting signal to the axonal and dendritic compartment
-
Back, S., Haas, P., Tschäpe, J. A., Gruebl, T., Kirsch, J., Müller, U., Beyreuther, K. and Kins, S. (2007). beta-amyloid precursor protein can be transported independent of any sorting signal to the axonal and dendritic compartment. J. Neurosci. Res. 85, 2580-2590.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 2580-2590
-
-
Back, S.1
Haas, P.2
Tschäpe, J.A.3
Gruebl, T.4
Kirsch, J.5
Müller, U.6
Beyreuther, K.7
Kins, S.8
-
5
-
-
0019216477
-
Trophic interactions between astroglial cells and hippocampal neurons in culture
-
Banker, G. A. (1980). Trophic interactions between astroglial cells and hippocampal neurons in culture. Science 209, 809-810.
-
(1980)
Science
, vol.209
, pp. 809-810
-
-
Banker, G.A.1
-
6
-
-
0032510834
-
The X11alpha protein slows cellular amyloid precursor protein processing and reduces abeta40 and abeta42 secretion
-
Borg, J. P., Yang, Y., De Taddéo-Borg, M., Margolis, B. and Turner, R. S. (1998). The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion. J. Biol. Chem. 273, 14761-14766.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14761-14766
-
-
Borg, J.P.1
Yang, Y.2
De Taddéo-Borg, M.3
Margolis, B.4
Turner, R.S.5
-
7
-
-
0032402095
-
Alzheimer amyloid protein precursor in the rat hippocampus: Transport and processing through the perforant path
-
Buxbaum, J. D., Thinakaran, G., Koliatsos, V., O'Callahan, J., Slunt, H. H., Price, D. L. and Sisodia, S. S. (1998). Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path. J. Neurosci. 18, 9629-9637.
-
(1998)
J. Neurosci.
, vol.18
, pp. 9629-9637
-
-
Buxbaum, J.D.1
Thinakaran, G.2
Koliatsos, V.3
O'Callahan, J.4
Slunt, H.H.5
Price, D.L.6
Sisodia, S.S.7
-
8
-
-
34547136377
-
Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid beta protein
-
Carey, R. M., Balcz, B. A., Lopez-Coviella, I. and Slack, B. E. (2005). Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid beta protein. BMC Cell Biol. 6, 30.
-
(2005)
BMC Cell Biol.
, vol.6
, pp. 30
-
-
Carey, R.M.1
Balcz, B.A.2
Lopez-Coviella, I.3
Slack, B.E.4
-
9
-
-
79955974543
-
Surface expression and limited proteolysis of ADAM10 are increased by a dominant negative inhibitor of dynamin
-
Carey, R. M., Blusztajn, J. K. and Slack, B. E. (2011). Surface expression and limited proteolysis of ADAM10 are increased by a dominant negative inhibitor of dynamin. BMC Cell Biol. 12, 20.
-
(2011)
BMC Cell Biol.
, vol.12
, pp. 20
-
-
Carey, R.M.1
Blusztajn, J.K.2
Slack, B.E.3
-
10
-
-
41549155927
-
Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo
-
Cirrito, J. R., Kang, J. E., Lee, J., Stewart, F. R., Verges, D. K., Silverio, L. M., Bu, G., Mennerick, S. and Holtzman, D. M. (2008). Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo. Neuron 58, 42-51.
-
(2008)
Neuron
, vol.58
, pp. 42-51
-
-
Cirrito, J.R.1
Kang, J.E.2
Lee, J.3
Stewart, F.R.4
Verges, D.K.5
Silverio, L.M.6
Bu, G.7
Mennerick, S.8
Holtzman, D.M.9
-
11
-
-
0027215550
-
Intraneuronal compartments of the amyloid precursor protein
-
Ferreira, A., Caceres, A. and Kosik, K. S. (1993). Intraneuronal compartments of the amyloid precursor protein. J. Neurosci. 13, 3112-3123.
-
(1993)
J. Neurosci.
, vol.13
, pp. 3112-3123
-
-
Ferreira, A.1
Caceres, A.2
Kosik, K.S.3
-
12
-
-
39549119763
-
Activity-induced synaptic capture and exocytosis of the neuronal serine protease neurotrypsin
-
Frischknecht, R., Fejtova, A., Viesti, M., Stephan, A. and Sonderegger, P. (2008). Activity-induced synaptic capture and exocytosis of the neuronal serine protease neurotrypsin. J. Neurosci. 28, 1568-1579.
-
(2008)
J. Neurosci.
, vol.28
, pp. 1568-1579
-
-
Frischknecht, R.1
Fejtova, A.2
Viesti, M.3
Stephan, A.4
Sonderegger, P.5
-
13
-
-
0034961544
-
Astrocyte and endothelial cell expression of ADAM 17 (TACE) in adult human CNS
-
Goddard, D. R., Bunning, R. A. and Woodroofe, M. N. (2001). Astrocyte and endothelial cell expression of ADAM 17 (TACE) in adult human CNS. Glia 34, 267-271.
-
(2001)
Glia
, vol.34
, pp. 267-271
-
-
Goddard, D.R.1
Bunning, R.A.2
Woodroofe, M.N.3
-
14
-
-
33745038221
-
Inhibition of APP trafficking by tau protein does not increase the generation of amyloid-beta peptides
-
Goldsbury, C., Mocanu, M. M., Thies, E., Kaether, C., Haass, C., Keller, P., Biernat, J., Mandelkow, E. and Mandelkow, E. M. (2006). Inhibition of APP trafficking by tau protein does not increase the generation of amyloid-beta peptides. Traffic 7, 873-888.
-
(2006)
Traffic
, vol.7
, pp. 873-888
-
-
Goldsbury, C.1
Mocanu, M.M.2
Thies, E.3
Kaether, C.4
Haass, C.5
Keller, P.6
Biernat, J.7
Mandelkow, E.8
Mandelkow, E.M.9
-
15
-
-
0042733013
-
Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and abeta production
-
Grbovic, O. M., Mathews, P. M., Jiang, Y., Schmidt, S. D., Dinakar, R., Summers-Terio, N. B., Ceresa, B. P., Nixon, R. A. and Cataldo, A. M. (2003). Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production. J. Biol. Chem. 278, 31261-31268.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31261-31268
-
-
Grbovic, O.M.1
Mathews, P.M.2
Jiang, Y.3
Schmidt, S.D.4
Dinakar, R.5
Summers-Terio, N.B.6
Ceresa, B.P.7
Nixon, R.A.8
Cataldo, A.M.9
-
16
-
-
0032506752
-
Novel tools for production and purification of recombinant adenoassociated virus vectors
-
Grimm, D., Kern, A., Rittner, K. and Kleinschmidt, J. A. (1998). Novel tools for production and purification of recombinant adenoassociated virus vectors. Hum. Gene Ther. 9, 2745-2760.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 2745-2760
-
-
Grimm, D.1
Kern, A.2
Rittner, K.3
Kleinschmidt, J.A.4
-
17
-
-
79955695654
-
Amyloid precursor protein is trafficked and secreted via synaptic vesicles
-
Groemer, T. W., Thiel, C. S., Holt, M., Riedel, D., Hua, Y., Hüve, J., Wilhelm, B. G. and Klingauf, J. (2011). Amyloid precursor protein is trafficked and secreted via synaptic vesicles. PLoS ONE 6, e18754.
-
(2011)
PLoS ONE
, vol.6
, pp. e18754
-
-
Groemer, T.W.1
Thiel, C.S.2
Holt, M.3
Riedel, D.4
Hua, Y.5
Hüve, J.6
Wilhelm, B.G.7
Klingauf, J.8
-
18
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
-
Haass, C. and Selkoe, D. J. (2007). Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat. Rev. Mol. Cell Biol. 8, 101-112.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
19
-
-
0026735070
-
Targeting of cell-surface beta-amyloid precursor protein to lysosomes: Alternative processing into amyloid-bearing fragments
-
Haass, C., Koo, E. H., Mellon, A., Hung, A. Y. and Selkoe, D. J. (1992). Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments. Nature 357, 500-503.
-
(1992)
Nature
, vol.357
, pp. 500-503
-
-
Haass, C.1
Koo, E.H.2
Mellon, A.3
Hung, A.Y.4
Selkoe, D.J.5
-
20
-
-
73649121986
-
Alcadein cleavages by amyloid β-precursor protein (APP) α- and γ-secretases generate small peptides, p3-alcs, indicating Alzheimer disease-related γ-secretase dysfunction
-
Hata, S., Fujishige, S., Araki, Y., Kato, N., Araseki, M., Nishimura, M., Hartmann, D., Saftig, P., Fahrenholz, F., Taniguchi, M. et al. (2009). Alcadein cleavages by amyloid β-precursor protein (APP) α- and γ-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related γ-secretase dysfunction. J. Biol. Chem. 284, 36024-36033.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 36024-36033
-
-
Hata, S.1
Fujishige, S.2
Araki, Y.3
Kato, N.4
Araseki, M.5
Nishimura, M.6
Hartmann, D.7
Saftig, P.8
Fahrenholz, F.9
Taniguchi, M.10
-
21
-
-
4644357534
-
Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation
-
He, W., Lu, Y., Qahwash, I., Hu, X. Y., Chang, A. and Yan, R. (2004). Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation. Nat. Med. 10, 959-965.
-
(2004)
Nat. Med.
, vol.10
, pp. 959-965
-
-
He, W.1
Lu, Y.2
Qahwash, I.3
Hu, X.Y.4
Chang, A.5
Yan, R.6
-
22
-
-
34247112490
-
Apolipoprotein receptor 2 and X11 α/β mediate apolipoprotein E-induced endocytosis of amyloid-β precursor protein and β-secretase, leading to amyloid-β production
-
He, X., Cooley, K., Chung, C. H., Dashti, N. and Tang, J. (2007). Apolipoprotein receptor 2 and X11 α/β mediate apolipoprotein E-induced endocytosis of amyloid-β precursor protein and β-secretase, leading to amyloid-β production. J. Neurosci. 27, 4052-4060.
-
(2007)
J. Neurosci.
, vol.27
, pp. 4052-4060
-
-
He, X.1
Cooley, K.2
Chung, C.H.3
Dashti, N.4
Tang, J.5
-
23
-
-
0036942683
-
The calsyntenins-A family of postsynaptic membrane proteins with distinct neuronal expression patterns
-
Hintsch, G., Zurlinden, A., Meskenaite, V., Steuble, M., Fink-Widmer, K., Kinter, J. and Sonderegger, P. (2002). The calsyntenins-a family of postsynaptic membrane proteins with distinct neuronal expression patterns. Mol. Cell. Neurosci. 21, 393-409.
-
(2002)
Mol. Cell. Neurosci.
, vol.21
, pp. 393-409
-
-
Hintsch, G.1
Zurlinden, A.2
Meskenaite, V.3
Steuble, M.4
Fink-Widmer, K.5
Kinter, J.6
Sonderegger, P.7
-
24
-
-
65549119787
-
Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production
-
Hoey, S. E., Williams, R. J. and Perkinton, M. S. (2009). Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production. J. Neurosci. 29, 4442-4460.
-
(2009)
J. Neurosci.
, vol.29
, pp. 4442-4460
-
-
Hoey, S.E.1
Williams, R.J.2
Perkinton, M.S.3
-
25
-
-
0038603918
-
A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1
-
Inomata, H., Nakamura, Y., Hayakawa, A., Takata, H., Suzuki, T., Miyazawa, K. and Kitamura, N. (2003). A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1. J. Biol. Chem. 278, 22946-22955.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22946-22955
-
-
Inomata, H.1
Nakamura, Y.2
Hayakawa, A.3
Takata, H.4
Suzuki, T.5
Miyazawa, K.6
Kitamura, N.7
-
26
-
-
77950613181
-
The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex
-
Jorissen, E., Prox, J., Bernreuther, C., Weber, S., Schwanbeck, R., Serneels, L., Snellinx, A., Craessaerts, K., Thathiah, A., Tesseur, I. et al. (2010). The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex. J. Neurosci. 30, 4833-4844.
-
(2010)
J. Neurosci.
, vol.30
, pp. 4833-4844
-
-
Jorissen, E.1
Prox, J.2
Bernreuther, C.3
Weber, S.4
Schwanbeck, R.5
Serneels, L.6
Snellinx, A.7
Craessaerts, K.8
Thathiah, A.9
Tesseur, I.10
-
27
-
-
0034075589
-
Axonal membrane proteins are transported in distinct carriers: A two-color video microscopy study in cultured hippocampal neurons
-
Kaether, C., Skehel, P. and Dotti, C. G. (2000). Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons. Mol. Biol. Cell 11, 1213-1224.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 1213-1224
-
-
Kaether, C.1
Skehel, P.2
Dotti, C.G.3
-
28
-
-
0033636136
-
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
-
Kamal, A., Stokin, G. B., Yang, Z., Xia, C. H. and Goldstein, L. S. (2000). Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron 28, 449-459.
-
(2000)
Neuron
, vol.28
, pp. 449-459
-
-
Kamal, A.1
Stokin, G.B.2
Yang, Z.3
Xia, C.H.4
Goldstein, L.S.5
-
29
-
-
0035818998
-
Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP
-
Kamal, A., Almenar-Queralt, A., LeBlanc, J. F., Roberts, E. A. and Goldstein, L. S. (2001). Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Nature 414, 643-648.
-
(2001)
Nature
, vol.414
, pp. 643-648
-
-
Kamal, A.1
Almenar-Queralt, A.2
LeBlanc, J.F.3
Roberts, E.A.4
Goldstein, L.S.5
-
30
-
-
0742269609
-
The mechanism of axon growth: What we have learned from the cell adhesion molecule L1
-
Kamiguchi, H. (2003). The mechanism of axon growth: what we have learned from the cell adhesion molecule L1. Mol. Neurobiol. 28, 219-228.
-
(2003)
Mol. Neurobiol.
, vol.28
, pp. 219-228
-
-
Kamiguchi, H.1
-
31
-
-
0034658292
-
Recycling of the cell adhesion molecule L1 in axonal growth cones
-
Kamiguchi, H. and Lemmon, V. (2000). Recycling of the cell adhesion molecule L1 in axonal growth cones. J. Neurosci. 20, 3676-3686.
-
(2000)
J. Neurosci.
, vol.20
, pp. 3676-3686
-
-
Kamiguchi, H.1
Lemmon, V.2
-
32
-
-
0029812945
-
Tau binds to the distal axon early in development of polarity in a microtubule- and microfilament dependent manner
-
Kempf, M., Clement, A., Faissner, A., Lee, G. and Brandt, R. (1996). Tau binds to the distal axon early in development of polarity in a microtubule- and microfilament dependent manner. J. Neurosci. 16, 5583-5592.
-
(1996)
J. Neurosci.
, vol.16
, pp. 5583-5592
-
-
Kempf, M.1
Clement, A.2
Faissner, A.3
Lee, G.4
Brandt, R.5
-
33
-
-
8744225623
-
Proteolytic processing of amyloid-beta precursor protein by secretases does not require cell surface transport
-
Khvotchev, M. and Südhof, T. C. (2004). Proteolytic processing of amyloid-beta precursor protein by secretases does not require cell surface transport. J. Biol. Chem. 279, 47101-47108.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 47101-47108
-
-
Khvotchev, M.1
Südhof, T.C.2
-
34
-
-
0042887148
-
Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes
-
Kinoshita, A., Fukumoto, H., Shah, T., Whelan, C. M., Irizarry, M. C. and Hyman, B. T. (2003). Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes. J. Cell Sci. 116, 3339-3346.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 3339-3346
-
-
Kinoshita, A.1
Fukumoto, H.2
Shah, T.3
Whelan, C.M.4
Irizarry, M.C.5
Hyman, B.T.6
-
35
-
-
33750151421
-
Subcellular trafficking of the amyloid precursor protein gene family and its pathogenic role in Alzheimer's disease
-
Kins, S., Lauther, N., Szodorai, A. and Beyreuther, K. (2006). Subcellular trafficking of the amyloid precursor protein gene family and its pathogenic role in Alzheimer's disease. Neurodegener. Dis. 3, 218-226.
-
(2006)
Neurodegener. Dis.
, vol.3
, pp. 218-226
-
-
Kins, S.1
Lauther, N.2
Szodorai, A.3
Beyreuther, K.4
-
36
-
-
0033569653
-
Membraneanchored metalloprotease MDC9 has an alpha-secretase activity responsible for processing the amyloid precursor protein
-
Koike, H., Tomioka, S., Sorimachi, H., Saido, T. C., Maruyama, K., Okuyama, A., Fujisawa-Sehara, A., Ohno, S., Suzuki, K. and Ishiura, S. (1999). Membraneanchored metalloprotease MDC9 has an alpha-secretase activity responsible for processing the amyloid precursor protein. Biochem. J. 343, 371-375.
-
(1999)
Biochem. J.
, vol.343
, pp. 371-375
-
-
Koike, H.1
Tomioka, S.2
Sorimachi, H.3
Saido, T.C.4
Maruyama, K.5
Okuyama, A.6
Fujisawa-Sehara, A.7
Ohno, S.8
Suzuki, K.9
Ishiura, S.10
-
37
-
-
15944413832
-
The non-amyloidogenic pathway: Structure and function of alpha-secretases
-
Kojro, E. and Fahrenholz, F. (2005). The non-amyloidogenic pathway: structure and function of alpha-secretases. Subcell. Biochem. 38, 105-127.
-
(2005)
Subcell. Biochem.
, vol.38
, pp. 105-127
-
-
Kojro, E.1
Fahrenholz, F.2
-
38
-
-
33746645123
-
Calsyntenin-1 docks vesicular cargo to kinesin-1
-
Konecna, A., Frischknecht, R., Kinter, J., Ludwig, A., Steuble, M., Meskenaite, V., Indermühle, M., Engel, M., Cen, C., Mateos, J. M. et al. (2006). Calsyntenin-1 docks vesicular cargo to kinesin-1. Mol. Biol. Cell 17, 3651-3663.
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 3651-3663
-
-
Konecna, A.1
Frischknecht, R.2
Kinter, J.3
Ludwig, A.4
Steuble, M.5
Meskenaite, V.6
Indermühle, M.7
Engel, M.8
Cen, C.9
Mateos, J.M.10
-
39
-
-
0028276801
-
Evidence that production and release of amyloid beta-protein involves the endocytic pathway
-
Koo, E. H. and Squazzo, S. L. (1994). Evidence that production and release of amyloid beta-protein involves the endocytic pathway. J. Biol. Chem. 269, 17386-17389.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17386-17389
-
-
Koo, E.H.1
Squazzo, S.L.2
-
40
-
-
0025056563
-
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport
-
Koo, E. H., Sisodia, S. S., Archer, D. R., Martin, L. J., Weidemann, A., Beyreuther, K., Fischer, P., Masters, C. L. and Price, D. L. (1990). Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport. Proc. Natl. Acad. Sci. USA 87, 1561-1565.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 1561-1565
-
-
Koo, E.H.1
Sisodia, S.S.2
Archer, D.R.3
Martin, L.J.4
Weidemann, A.5
Beyreuther, K.6
Fischer, P.7
Masters, C.L.8
Price, D.L.9
-
41
-
-
0029950149
-
Trafficking of cellsurface amyloid beta-protein precursor. I. Secretion, endocytosis and recycling as detected by labeled monoclonal antibody
-
Koo, E. H., Squazzo, S. L., Selkoe, D. J. and Koo, C. H. (1996). Trafficking of cellsurface amyloid beta-protein precursor. I. Secretion, endocytosis and recycling as detected by labeled monoclonal antibody. J. Cell Sci. 109, 991-998.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 991-998
-
-
Koo, E.H.1
Squazzo, S.L.2
Selkoe, D.J.3
Koo, C.H.4
-
42
-
-
77956392552
-
ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons
-
Kuhn, P.-H., Wang, H., Dislich, B., Colombo, A., Zeitschel, U., Ellwart, J. W., Kremmer, E., Roßner, S. and Lichtenthaler, S. F. (2010). ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons. EMBO J. 29, 3020-3032.
-
(2010)
EMBO J.
, vol.29
, pp. 3020-3032
-
-
Kuhn, P.-H.1
Wang, H.2
Dislich, B.3
Colombo, A.4
Zeitschel, U.5
Ellwart, J.W.6
Kremmer, E.7
Roßner, S.8
Lichtenthaler, S.F.9
-
43
-
-
0033616716
-
Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease
-
Lammich, S., Kojro, E., Postina, R., Gilbert, S., Pfeiffer, R., Jasionowski, M., Haass, C. and Fahrenholz, F. (1999). Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease. Proc. Natl. Acad. Sci. USA 96, 3922-3927.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3922-3927
-
-
Lammich, S.1
Kojro, E.2
Postina, R.3
Gilbert, S.4
Pfeiffer, R.5
Jasionowski, M.6
Haass, C.7
Fahrenholz, F.8
-
44
-
-
80755139512
-
Mechanisms of polarized membrane trafficking in neurons - focusing in on endosomes
-
Lasiecka, Z. M. and Winckler, B. (2011). Mechanisms of polarized membrane trafficking in neurons - focusing in on endosomes. Mol. Cell. Neurosci. 48, 278-287.
-
(2011)
Mol. Cell. Neurosci.
, vol.48
, pp. 278-287
-
-
Lasiecka, Z.M.1
Winckler, B.2
-
45
-
-
20044396527
-
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: Revisited
-
Lazarov, O., Morfini, G. A., Lee, E. B., Farah, M. H., Szodorai, A., DeBoer, S. R., Koliatsos, V. E., Kins, S., Lee, V. M., Wong, P. C. et al. (2005). Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited. J. Neurosci. 25, 2386-2395.
-
(2005)
J. Neurosci.
, vol.25
, pp. 2386-2395
-
-
Lazarov, O.1
Morfini, G.A.2
Lee, E.B.3
Farah, M.H.4
Szodorai, A.5
DeBoer, S.R.6
Koliatsos, V.E.7
Kins, S.8
Lee, V.M.9
Wong, P.C.10
-
46
-
-
64849104680
-
Calsyntenins mediate TGN exit of APP in a kinesin-1-dependent manner
-
Ludwig, A., Blume, J., Diep, T. M., Yuan, J., Mateos, J. M., Leuthäuser, K., Steuble, M., Streit, P. and Sonderegger, P. (2009). Calsyntenins mediate TGN exit of APP in a kinesin-1-dependent manner. Traffic 10, 572-589.
-
(2009)
Traffic
, vol.10
, pp. 572-589
-
-
Ludwig, A.1
Blume, J.2
Diep, T.M.3
Yuan, J.4
Mateos, J.M.5
Leuthäuser, K.6
Steuble, M.7
Streit, P.8
Sonderegger, P.9
-
47
-
-
0031031006
-
Trafficking of cell-surface beta-amyloid precursor protein: Evidence that a sorting intermediate participates in synaptic vesicle recycling
-
Marquez-Sterling, N. R., Lo, A. C., Sisodia, S. S. and Koo, E. H. (1997). Trafficking of cell-surface beta-amyloid precursor protein: evidence that a sorting intermediate participates in synaptic vesicle recycling. J. Neurosci. 17, 140-151.
-
(1997)
J. Neurosci.
, vol.17
, pp. 140-151
-
-
Marquez-Sterling, N.R.1
Lo, A.C.2
Sisodia, S.S.3
Koo, E.H.4
-
48
-
-
0141532147
-
Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1
-
Matsuda, S., Matsuda, Y. and D'Adamio, L. (2003). Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1. J. Biol. Chem. 278, 38601-38606.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38601-38606
-
-
Matsuda, S.1
Matsuda, Y.2
D'Adamio, L.3
-
50
-
-
0035937770
-
The neuronal adaptor protein X11alpha interacts with the copper chaperone for SOD1 and regulates SOD1 activity
-
McLoughlin, D. M., Standen, C. L., Lau, K. F., Ackerley, S., Bartnikas, T. P., Gitlin, J. D. and Miller, C. C. (2001). The neuronal adaptor protein X11alpha interacts with the copper chaperone for SOD1 and regulates SOD1 activity. J. Biol. Chem. 276, 9303-9307.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9303-9307
-
-
McLoughlin, D.M.1
Standen, C.L.2
Lau, K.F.3
Ackerley, S.4
Bartnikas, T.P.5
Gitlin, J.D.6
Miller, C.C.7
-
51
-
-
33646584550
-
The X11 proteins, abeta production and Alzheimer's disease
-
Miller, C. C., McLoughlin, D. M., Lau, K. F., Tennant, M. E. and Rogelj, B. (2006). The X11 proteins, Abeta production and Alzheimer's disease. Trends Neurosci. 29, 280-285.
-
(2006)
Trends Neurosci.
, vol.29
, pp. 280-285
-
-
Miller, C.C.1
McLoughlin, D.M.2
Lau, K.F.3
Tennant, M.E.4
Rogelj, B.5
-
52
-
-
0036469290
-
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility
-
Morfini, G., Szebenyi, G., Elluru, R., Ratner, N. and Brady, S. T. (2002). Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility. EMBO J. 21, 281-293.
-
(2002)
EMBO J.
, vol.21
, pp. 281-293
-
-
Morfini, G.1
Szebenyi, G.2
Elluru, R.3
Ratner, N.4
Brady, S.T.5
-
53
-
-
33748755837
-
Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid beta-protein
-
Murayama, K. S., Kametani, F., Saito, S., Kume, H., Akiyama, H. and Araki, W. (2006). Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid beta-protein. Eur. J. Neurosci. 24, 1237-1244.
-
(2006)
Eur. J. Neurosci.
, vol.24
, pp. 1237-1244
-
-
Murayama, K.S.1
Kametani, F.2
Saito, S.3
Kume, H.4
Akiyama, H.5
Araki, W.6
-
54
-
-
63849105306
-
The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites
-
Muresan, V., Varvel, N. H., Lamb, B. T. and Muresan, Z. (2009). The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites. J. Neurosci. 29, 3565-3578.
-
(2009)
J. Neurosci.
, vol.29
, pp. 3565-3578
-
-
Muresan, V.1
Varvel, N.H.2
Lamb, B.T.3
Muresan, Z.4
-
55
-
-
0026476297
-
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
-
Nitsch, R. M., Slack, B. E., Wurtman, R. J. and Growdon, J. H. (1992). Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science 258, 304-307.
-
(1992)
Science
, vol.258
, pp. 304-307
-
-
Nitsch, R.M.1
Slack, B.E.2
Wurtman, R.J.3
Growdon, J.H.4
-
56
-
-
0033516554
-
Mutagenesis identifies new signals for betaamyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including abeta42
-
Perez, R. G., Soriano, S., Hayes, J. D., Ostaszewski, B., Xia, W., Selkoe, D. J., Chen, X., Stokin, G. B. and Koo, E. H. (1999). Mutagenesis identifies new signals for betaamyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42. J. Biol. Chem. 274, 18851-18856.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18851-18856
-
-
Perez, R.G.1
Soriano, S.2
Hayes, J.D.3
Ostaszewski, B.4
Xia, W.5
Selkoe, D.J.6
Chen, X.7
Stokin, G.B.8
Koo, E.H.9
-
57
-
-
33746593662
-
Alzheimer's disease beta-amyloid peptides are released in association with exosomes
-
Rajendran, L., Honsho, M., Zahn, T. R., Keller, P., Geiger, K. D., Verkade, P. and Simons, K. (2006). Alzheimer's disease beta-amyloid peptides are released in association with exosomes. Proc. Natl. Acad. Sci. USA 103, 11172-11177.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 11172-11177
-
-
Rajendran, L.1
Honsho, M.2
Zahn, T.R.3
Keller, P.4
Geiger, K.D.5
Verkade, P.6
Simons, K.7
-
58
-
-
42549148456
-
Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting
-
Rajendran, L., Schneider, A., Schlechtingen, G., Weidlich, S., Ries, J., Braxmeier, T., Schwille, P., Schulz, J. B., Schroeder, C., Simons, M. et al. (2008). Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting. Science 320, 520-523.
-
(2008)
Science
, vol.320
, pp. 520-523
-
-
Rajendran, L.1
Schneider, A.2
Schlechtingen, G.3
Weidlich, S.4
Ries, J.5
Braxmeier, T.6
Schwille, P.7
Schulz, J.B.8
Schroeder, C.9
Simons, M.10
-
59
-
-
0033525037
-
Metalloprotease-disintegrin MDC9: Intracellular maturation and catalytic activity
-
Roghani, M., Becherer, J. D., Moss, M. L., Atherton, R. E., Erdjument-Bromage, H., Arribas, J., Blackburn, R. K., Weskamp, G., Tempst, P. and Blobel, C. P. (1999). Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity. J. Biol. Chem. 274, 3531-3540.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 3531-3540
-
-
Roghani, M.1
Becherer, J.D.2
Moss, M.L.3
Atherton, R.E.4
Erdjument-Bromage, H.5
Arribas, J.6
Blackburn, R.K.7
Weskamp, G.8
Tempst, P.9
Blobel, C.P.10
-
60
-
-
33847194657
-
Axonal accumulation of synaptic markers in APP transgenic drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity
-
Rusu, P., Jansen, A., Soba, P., Kirsch, J., Löwer, A., Merdes, G., Kuan, Y. H., Jung, A., Beyreuther, K., Kjaerulff, O. et al. (2007). Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity. Eur. J. Neurosci. 25, 1079-1086.
-
(2007)
Eur. J. Neurosci.
, vol.25
, pp. 1079-1086
-
-
Rusu, P.1
Jansen, A.2
Soba, P.3
Kirsch, J.4
Löwer, A.5
Merdes, G.6
Kuan, Y.H.7
Jung, A.8
Beyreuther, K.9
Kjaerulff, O.10
-
61
-
-
0026721943
-
Beta-amyloid precursor protein cleavage by a membrane-bound protease
-
Sisodia, S. S. (1992a). Beta-amyloid precursor protein cleavage by a membrane-bound protease. Proc. Natl. Acad. Sci. USA 89, 6075-6079.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6075-6079
-
-
Sisodia, S.S.1
-
62
-
-
0027056827
-
Secretion of the beta-amyloid precursor protein
-
Sisodia, S. S. (1992b). Secretion of the beta-amyloid precursor protein. Ann. N. Y. Acad. Sci. 674, 53-57.
-
(1992)
Ann. N. Y. Acad. Sci.
, vol.674
, pp. 53-57
-
-
Sisodia, S.S.1
-
63
-
-
0035424693
-
Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzyme
-
Slack, B. E., Ma, L. K. and Seah, C. C. (2001). Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzyme. Biochem. J. 357, 787-794.
-
(2001)
Biochem. J.
, vol.357
, pp. 787-794
-
-
Slack, B.E.1
Ma, L.K.2
Seah, C.C.3
-
64
-
-
33749042749
-
Sorting through the cell biology of Alzheimer's disease: Intracellular pathways to pathogenesis
-
Small, S. A. and Gandy, S. (2006). Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis. Neuron 52, 15-31.
-
(2006)
Neuron
, vol.52
, pp. 15-31
-
-
Small, S.A.1
Gandy, S.2
-
65
-
-
78049353997
-
Molecular characterization of a trafficking organelle: Dissecting the axonal paths of calsyntenin-1 transport vesicles
-
Steuble, M., Gerrits, B., Ludwig, A., Mateos, J. M., Diep, T. M., Tagaya, M., Stephan, A., Schätzle, P., Kunz, B., Streit, P. et al. (2010). Molecular characterization of a trafficking organelle: dissecting the axonal paths of calsyntenin-1 transport vesicles. Proteomics 10, 3775-3788.
-
(2010)
Proteomics
, vol.10
, pp. 3775-3788
-
-
Steuble, M.1
Gerrits, B.2
Ludwig, A.3
Mateos, J.M.4
Diep, T.M.5
Tagaya, M.6
Stephan, A.7
Schätzle, P.8
Kunz, B.9
Streit, P.10
-
66
-
-
70949085531
-
APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle
-
Szodorai, A., Kuan, Y. H., Hunzelmann, S., Engel, U., Sakane, A., Sasaki, T., Takai, Y., Kirsch, J., Müller, U., Beyreuther, K. et al. (2009). APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle. J. Neurosci. 29, 14534-14544.
-
(2009)
J. Neurosci.
, vol.29
, pp. 14534-14544
-
-
Szodorai, A.1
Kuan, Y.H.2
Hunzelmann, S.3
Engel, U.4
Sakane, A.5
Sasaki, T.6
Takai, Y.7
Kirsch, J.8
Müller, U.9
Beyreuther, K.10
-
67
-
-
10144263284
-
The betaamyloid domain is essential for axonal sorting of amyloid precursor protein
-
Tienari, P. J., De Strooper, B., Ikonen, E., Simons, M., Weidemann, A., Czech, C., Hartmann, T., Ida, N., Multhaup, G., Masters, C. L. et al. (1996). The betaamyloid domain is essential for axonal sorting of amyloid precursor protein. EMBO J. 15, 5218-5229.
-
(1996)
EMBO J.
, vol.15
, pp. 5218-5229
-
-
Tienari, P.J.1
De Strooper, B.2
Ikonen, E.3
Simons, M.4
Weidemann, A.5
Czech, C.6
Hartmann, T.7
Ida, N.8
Multhaup, G.9
Masters, C.L.10
-
68
-
-
0033568874
-
The drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction
-
Torroja, L., Packard, M., Gorczyca, M., White, K. and Budnik, V. (1999). The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction. J. Neurosci. 19, 7793-7803.
-
(1999)
J. Neurosci.
, vol.19
, pp. 7793-7803
-
-
Torroja, L.1
Packard, M.2
Gorczyca, M.3
White, K.4
Budnik, V.5
-
69
-
-
84863518335
-
Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production
-
Vagnoni, A., Perkinton, M. S., Gray, E. H., Francis, P. T., Noble, W. and Miller, C. C. J. (2012). Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production. Hum. Mol. Genet. 21, 2845-2854.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 2845-2854
-
-
Vagnoni, A.1
Perkinton, M.S.2
Gray, E.H.3
Francis, P.T.4
Noble, W.5
Miller, C.C.J.6
-
70
-
-
4344630985
-
BACE1: The beta-secretase enzyme in Alzheimer's disease
-
Vassar, R. (2004). BACE1: the beta-secretase enzyme in Alzheimer's disease. J. Mol. Neurosci. 23, 105-114.
-
(2004)
J. Mol. Neurosci.
, vol.23
, pp. 105-114
-
-
Vassar, R.1
-
71
-
-
0035147474
-
Calsyntenin-1, a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain
-
Vogt, L., Schrimpf, S. P., Meskenaite, V., Frischknecht, R., Kinter, J., Leone, D. P., Ziegler, U. and Sonderegger, P. (2001). Calsyntenin-1, a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain. Mol. Cell. Neurosci. 17, 151-166.
-
(2001)
Mol. Cell. Neurosci.
, vol.17
, pp. 151-166
-
-
Vogt, L.1
Schrimpf, S.P.2
Meskenaite, V.3
Frischknecht, R.4
Kinter, J.5
Leone, D.P.6
Ziegler, U.7
Sonderegger, P.8
-
72
-
-
0036170534
-
Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life
-
Weskamp, G., Cai, H., Brodie, T. A., Higashyama, S., Manova, K., Ludwig, T. and Blobel, C. P. (2002). Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life. Mol. Cell. Biol. 22, 1537-1544.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1537-1544
-
-
Weskamp, G.1
Cai, H.2
Brodie, T.A.3
Higashyama, S.4
Manova, K.5
Ludwig, T.6
Blobel, C.P.7
-
73
-
-
0020589824
-
Acidification of endocytic vesicles by an ATP-dependent proton pump
-
Yamashiro, D. J., Fluss, S. R. and Maxfield, F. R. (1983). Acidification of endocytic vesicles by an ATP-dependent proton pump. J. Cell Biol. 97, 929-934.
-
(1983)
J. Cell Biol.
, vol.97
, pp. 929-934
-
-
Yamashiro, D.J.1
Fluss, S.R.2
Maxfield, F.R.3
-
74
-
-
0029934134
-
Trafficking of cell-surface amyloid beta-protein precursor. II. Endocytosis, recycling and lysosomal targeting detected by immunolocalization
-
Yamazaki, T., Koo, E. H. and Selkoe, D. J. (1996). Trafficking of cell-surface amyloid beta-protein precursor. II. Endocytosis, recycling and lysosomal targeting detected by immunolocalization. J. Cell Sci. 109, 999-1008.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 999-1008
-
-
Yamazaki, T.1
Koo, E.H.2
Selkoe, D.J.3
|