The sheddase ADAM10 is a potent modulator of prion disease

eLife

Volumn 2015, Issue 4, 2015, Pages 1-50

  Altmeppen, Hermann C ^a   Prox, Johannes ^b   Krasemann, Susanne ^a   Puig, Berta ^a   Kruszewski, Katharina ^a   Dohler, Frank ^a   Bernreuther, Christian ^a   Hoxha, Ana ^a   Linsenmeier, Luise ^a   Sikorska, Beata ^c   Liberski, Pawel P ^c   Bartsch, Udo ^a   Saftig, Paul ^b   Glatze, Markus ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

ADAM10; Neurodegeneration; Prion disease; Proteolytic processing; Shedding

Indexed keywords

ADAM10 ENDOPEPTIDASE; CALPAIN; PRION PROTEIN; PROTEINASE; ADAM PROTEIN; ADAM10 PROTEIN, HUMAN; MEMBRANE PROTEIN; SECRETASE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MOUSE; NEURAL STEM CELL; NEURITE; NONHUMAN; PRION DISEASE; PROTEIN DEPLETION; PROTEIN PROCESSING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPATIOTEMPORAL ANALYSIS; WESTERN BLOTTING; ANIMAL; FOREBRAIN; HUMAN; KNOCKOUT MOUSE; METABOLISM;

MUS;

ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CALPAIN; HUMANS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PRION DISEASES; PROSENCEPHALON; PRPC PROTEINS;

EID: 84964698898     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.04260     Document Type: Article

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