-
1
-
-
0032076463
-
Prion protein biology
-
DOI 10.1016/S0092-8674(00)81163-0
-
Prusiner, S. B., Scott, M. R., DeArmond, S. J., and Cohen, F. E. (1998) Prion protein biology. Cell 93, 337-348 (Pubitemid 28232079)
-
(1998)
Cell
, vol.93
, Issue.3
, pp. 337-348
-
-
Prusiner, S.B.1
Scott, M.R.2
DeArmond, S.J.3
Cohen, F.E.4
-
2
-
-
0027333557
-
Cellular processing of β-amyloid precursor protein and the genesis of amyloid β-peptide
-
Haass, C., and Selkoe, D. J. (1993) Cellular processing of β-amyloid precursor protein and the genesis of amyloid β-peptide. Cell 75, 1039-1042
-
(1993)
Cell
, vol.75
, pp. 1039-1042
-
-
Haass, C.1
Selkoe, D.J.2
-
3
-
-
0029379605
-
Processing of the β-amyloid precursor protein and its regulation in Alzheimer's disease
-
Checler, F. (1995) Processing of the β-amyloid precursor protein and its regulation in Alzheimer's disease. J. Neurochem. 65, 1431-1444
-
(1995)
J. Neurochem.
, vol.65
, pp. 1431-1444
-
-
Checler, F.1
-
4
-
-
0027478347
-
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein
-
DOI 10.1016/0896-6273(93)90315-I
-
Mattson, M. P., Cheng, B., Culwell, A. R., Esch, F. S., Lieberburg, I., and Rydel, R. E. (1993) Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein. Neuron 10, 243-254 (Pubitemid 23079546)
-
(1993)
Neuron
, vol.10
, Issue.2
, pp. 243-254
-
-
Mattson, M.P.1
Cheng, B.2
Culwell, A.R.3
Esch, F.S.4
Lieberburg, I.5
Rydel, R.E.6
-
5
-
-
0028169905
-
Secreted forms of β-amyloid precursor protein protect hippocampal neurons against amyloid β-peptide-induced oxidative injury
-
Goodman, Y., and Mattson, M. P. (1994) Secreted forms of β-amyloid precursor protein protect hippocampal neurons against amyloid β-peptide-induced oxidative injury. Exp. Neurol. 128, 1-12
-
(1994)
Exp. Neurol.
, vol.128
, pp. 1-12
-
-
Goodman, Y.1
Mattson, M.P.2
-
6
-
-
0030763739
-
Synaptic β-amyloid precursor proteins increase with learning capacity in rats
-
DOI 10.1016/S0306-4522(97)00120-6, PII S0306452297001206
-
Huber, G., Bailly, Y., Martin, J. R., Mariani, J., and Brugg, B. (1997) Synaptic β-amyloid precursor proteins increase with learning capacity in rats. Neuroscience 80, 313-320 (Pubitemid 27334583)
-
(1997)
Neuroscience
, vol.80
, Issue.2
, pp. 313-320
-
-
Huber, G.1
Bailly, Y.2
Martin, J.R.3
Mariani, J.4
Brugg, B.5
-
7
-
-
0033595706
-
β-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., Teplow, D. B., Ross, S., Amarante, P., Loeloff, R., Luo, Y., Fisher, S., Fuller, J., Edenson, S., Lile, J., Jarosinski, M. A., Biere, A. L., Curran, E., Burgess, T., Louis, J. C., Collins, F., Treanor, J., Rogers, G., and Citron, M. (1999) β-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286, 735-741
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
8
-
-
0035116273
-
Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation
-
DOI 10.1038/85059
-
Luo, Y., Bolon, B., Kahn, S., Bennett, B. D., Babu-Khan, S., Denis, P., Fan, W., Kha, H., Zhang, J., Gong, Y., Martin, L., Louis, J. C., Yan, Q., Richards, W. G., Citron, M., and Vassar, R. (2001) Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation. Nat. Neurosci. 4, 231-232 (Pubitemid 32194866)
-
(2001)
Nature Neuroscience
, vol.4
, Issue.3
, pp. 231-232
-
-
Luo, Y.1
Bolon, B.2
Kahn, S.3
Bennett, B.D.4
Babu-Khan, S.5
Denis, P.6
Fan, W.7
Kha, H.8
Zhang, J.9
Gong, Y.10
Martin, L.11
Louis, J.-C.12
Yan, Q.13
Richards, W.G.14
Citron, M.15
Vassar, R.16
-
9
-
-
0023663071
-
Scrapie prion protein contains a phosphatidylinositol glycolipid
-
Stahl, N., Borchelt, D. R., Hsiao, K., and Prusiner, S. B. (1987) Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell 51, 229-240
-
(1987)
Cell
, vol.51
, pp. 229-240
-
-
Stahl, N.1
Borchelt, D.R.2
Hsiao, K.3
Prusiner, S.B.4
-
10
-
-
0028297994
-
A glycosylphosphatidylinositol (GPI)-negative phenotype produced in Leishmania major by GPI phospholipase C from Trypanosoma brucei: Topography of two GPI pathways
-
Mensa-Wilmot, K., LeBowitz, J. H., Chang, K. P., al-Qahtani, A., McGwire, B. S., Tucker, S., and Morris, J. C. (1994) A glycosylphosphatidylinositol (GPI)-negative phenotype produced in Leishmania major by GPI phospholipase C from Trypanosoma brucei: topography of two GPI pathways. J. Cell Biol. 124, 935-947 (Pubitemid 24109396)
-
(1994)
Journal of Cell Biology
, vol.124
, Issue.6
, pp. 935-947
-
-
Mensa-Wilmot, K.1
LeBowitz, J.H.2
Chang, K.-P.3
Al-Qahtani, A.4
McGwire, B.S.5
Tucker, S.6
Morris, J.C.7
-
11
-
-
0034634655
-
Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons
-
Vincent, B., Paitel, E., Frobert, Y., Lehmann, S., Grassi, J., and Checler, F. (2000) Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons. J. Biol. Chem. 275, 35612-35616
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35612-35616
-
-
Vincent, B.1
Paitel, E.2
Frobert, Y.3
Lehmann, S.4
Grassi, J.5
Checler, F.6
-
12
-
-
0035851151
-
The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein
-
Vincent, B., Paitel, E., Saftig, P., Frobert, Y., Hartmann, D., De Strooper, B., Grassi, J., Lopez-Perez, E., and Checler, F. (2001) The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein. J. Biol. Chem. 276, 37743-37746
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37743-37746
-
-
Vincent, B.1
Paitel, E.2
Saftig, P.3
Frobert, Y.4
Hartmann, D.5
De Strooper, B.6
Grassi, J.7
Lopez-Perez, E.8
Checler, F.9
-
13
-
-
42149140619
-
c cleavage by α-secretase: Mechanistic and therapeutic perspectives
-
DOI 10.2174/156720508783954749
-
Vincent, B., Cisse, M. A., Sunyach, C., Guillot-Sestier, M. V., and Checler, F. (2008) Regulation of βAPP and PrPc cleavage by α-secretase: mechanistic and therapeutic perspectives. Curr. Alzheimer Res. 5, 202-211 (Pubitemid 351536345)
-
(2008)
Current Alzheimer Research
, vol.5
, Issue.2
, pp. 202-211
-
-
Vincent, B.1
Cisse, M.A.2
Sunyach, C.3
Guillot-Sestier, M.-V.4
Checler, F.5
-
14
-
-
79957510525
-
Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo
-
Altmeppen, H. C., Prox, J., Puig, B., Kluth, M. A., Bernreuther, C., Thurm, D., Jorissen, E., Petrowitz, B., Bartsch, U., De Strooper, B., Saftig, P., and Glatzel, M. (2011) Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo. Mol. Neurodegener. 6, 36
-
(2011)
Mol. Neurodegener.
, vol.6
, pp. 36
-
-
Altmeppen, H.C.1
Prox, J.2
Puig, B.3
Kluth, M.A.4
Bernreuther, C.5
Thurm, D.6
Jorissen, E.7
Petrowitz, B.8
Bartsch, U.9
De Strooper, B.10
Saftig, P.11
Glatzel, M.12
-
15
-
-
34247115682
-
3 muscarinic receptors control physiological processing of cellular prion by modulating ADAM17 phosphorylation and activity
-
DOI 10.1523/JNEUROSCI.5293-06.2007
-
Alfa Cissé, M., Sunyach, C., Slack, B. E., Fisher, A., Vincent, B., and Checler, F. (2007) M1 and M3 muscarinic receptors control physiological processing of cellular prion by modulating ADAM17 phosphorylation and activity. J. Neurosci. 27, 4083-4092 (Pubitemid 46597172)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.15
, pp. 4083-4092
-
-
Cisse, M.A.1
Sunyach, C.2
Slack, B.E.3
Fisher, A.4
Vincent, B.5
Checler, F.6
-
16
-
-
80051685988
-
The extracellular regulated kinase-1 (ERK1) controls regulated α-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein
-
Cissé, M., Duplan, E., Guillot-Sestier, M. V., Rumigny, J., Bauer, C., Pagès, G., Orzechowski, H. D., Slack, B. E., Checler, F., and Vincent, B. (2011) The extracellular regulated kinase-1 (ERK1) controls regulated α-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein. J. Biol. Chem. 286, 29192-29206
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 29192-29206
-
-
Cissé, M.1
Duplan, E.2
Guillot-Sestier, M.V.3
Rumigny, J.4
Bauer, C.5
Pagès, G.6
Orzechowski, H.D.7
Slack, B.E.8
Checler, F.9
Vincent, B.10
-
17
-
-
79957646992
-
ERK1-independent α-secretase cut of β-amyloid precursor protein via M1 muscarinic receptors and PKCα/ε
-
Cisse, M., Braun, U., Leitges, M., Fisher, A., Pages, G., Checler, F., and Vincent, B. (2011) ERK1-independent α-secretase cut of β-amyloid precursor protein via M1 muscarinic receptors and PKCα/ε. Mol. Cell. Neurosci. 47, 223-232
-
(2011)
Mol. Cell. Neurosci.
, vol.47
, pp. 223-232
-
-
Cisse, M.1
Braun, U.2
Leitges, M.3
Fisher, A.4
Pages, G.5
Checler, F.6
Vincent, B.7
-
18
-
-
72149127389
-
The β-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo
-
Guillot-Sestier, M. V., Sunyach, C., Druon, C., Scarzello, S., and Checler, F. (2009) The β-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo. J. Biol. Chem. 284, 35973-35986
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 35973-35986
-
-
Guillot-Sestier, M.V.1
Sunyach, C.2
Druon, C.3
Scarzello, S.4
Checler, F.5
-
19
-
-
19944434132
-
Intracellular Aβ42 activates p53 promoter: A pathway to neurodegeneration in Alzheimer's disease
-
DOI 10.1096/fj.04-2637fje
-
Ohyagi, Y., Asahara, H., Chui, D. H., Tsuruta, Y., Sakae, N., Miyoshi, K., Yamada, T., Kikuchi, H., Taniwaki, T., Murai, H., Ikezoe, K., Furuya, H., Kawarabayashi, T., Shoji, M., Checler, F., Iwaki, T., Makifuchi, T., Takeda, K., Kira, J., and Tabira, T. (2005) Intracellular Aβ42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease. FASEB J. 19, 255-257 (Pubitemid 40189273)
-
(2005)
FASEB Journal
, vol.19
, Issue.2
, pp. 255-257
-
-
Ohyagi, Y.1
Asahara, H.2
Chui, D.-H.3
Tsuruta, Y.4
Sakae, N.5
Miyoshi, K.6
Yamada, T.7
Kikuchi, H.8
Taniwaki, T.9
Murai, H.10
Ikezoe, K.11
Furuya, H.12
Kawarabayashi, T.13
Shoji, M.14
Checler, F.15
Iwaki, T.16
Makifuchi, T.17
Takeda, K.18
Kira, J.-I.19
Tabira, T.20
more..
-
20
-
-
0035736326
-
Endogenous β-amyloid production in presenilin-deficient embryonic mouse fibroblasts
-
DOI 10.1038/ncb1101-1030
-
Armogida, M., Petit, A., Vincent, B., Scarzello, S., da Costa, C. A., and Checler, F. (2001) Endogenous β-amyloid production in presenilin-deficient embryonic mouse fibroblasts. Nat. Cell Biol. 3, 1030-1033 (Pubitemid 34428750)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.11
, pp. 1030-1033
-
-
Armogida, M.1
Petit, A.2
Vincent, B.3
Scarzello, S.4
Da, C.C.A.5
Checler, F.6
-
21
-
-
0031001110
-
Examination of the role of endopeptidase 3.4.24.15 in Aβ secretion by human transfected cells
-
DOI 10.1038/sj.bjp.0701151
-
Chevallier, N., Jiracek, J., Vincent, B., Baur, C. P., Spillantini, M. G., Goedert, M., Dive, V., and Checler, F. (1997) Examination of the role of endopeptidase 3.4.24.15 in Aβ secretion by human transfected cells. Br. J. Pharmacol. 121, 556-562 (Pubitemid 27226310)
-
(1997)
British Journal of Pharmacology
, vol.121
, Issue.3
, pp. 556-562
-
-
Chevallier, N.1
Jiracek, J.2
Vincent, B.3
Baur, C.-P.4
Spillantini, M.-G.5
Goedert, M.6
Dive, V.7
Checler, F.8
-
22
-
-
0033775709
-
Total inactivation of γ-secretase activity in presenilin-deficient embryonic stem cells
-
Herreman, A., Serneels, L., Annaert, W., Collen, D., Schoonjans, L., and De Strooper, B. (2000) Total inactivation of γ-secretase activity in presenilin-deficient embryonic stem cells. Nat. Cell Biol. 2, 461-462
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 461-462
-
-
Herreman, A.1
Serneels, L.2
Annaert, W.3
Collen, D.4
Schoonjans, L.5
De Strooper, B.6
-
23
-
-
0034329291
-
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members
-
Heber, S., Herms, J., Gajic, V., Hainfellner, J., Aguzzi, A., Rülicke, T., von Kretzschmar, H., von Koch, C., Sisodia, S., Tremml, P., Lipp, H. P., Wolfer, D. P., and Müller, U. (2000) Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. J. Neurosci. 20, 7951-7963
-
(2000)
J. Neurosci.
, vol.20
, pp. 7951-7963
-
-
Heber, S.1
Herms, J.2
Gajic, V.3
Hainfellner, J.4
Aguzzi, A.5
Rülicke, T.6
Von Kretzschmar, H.7
Von Koch, C.8
Sisodia, S.9
Tremml, P.10
Lipp, H.P.11
Wolfer, D.P.12
Müller, U.13
-
24
-
-
33846024069
-
The low density lipoprotein receptor-related protein functions as an endocytic receptor for decorin
-
DOI 10.1074/jbc.M602919200
-
Brandan, E., Retamal, C., Cabello-Verrugio, C., and Marzolo, M. P. (2006) The low density lipoprotein receptor-related protein functions as an endocytic receptor for decorin. J. Biol. Chem. 281, 31562-31571 (Pubitemid 46041422)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.42
, pp. 31562-31571
-
-
Brandan, E.1
Retamal, C.2
Cabello-Verrugio, C.3
Marzolo, M.-P.4
-
25
-
-
0029781361
-
Distinct properties of neuronal and astrocytic endopeptidase 3.4.24.16: A study on differentiation, subcellular distribution, and secretion processes
-
Vincent, B., Beaudet, A., Dauch, P., Vincent, J. P., and Checler, F. (1996) Distinct properties of neuronal and astrocytic endopeptidase 3.4.24.16: a study on differentiation, subcellular distribution, and secretion processes. J. Neurosci. 16, 5049-5059 (Pubitemid 26269665)
-
(1996)
Journal of Neuroscience
, vol.16
, Issue.16
, pp. 5049-5059
-
-
Vincent, B.1
Beaudet, A.2
Dauch, P.3
Vincent, J.-P.4
Checler, F.5
-
26
-
-
33745632662
-
Presenilin-dependent γ-secretase-mediated control of p53-associated cell death in Alzheimer's disease
-
Alves da Costa, C., Sunyach, C., Pardossi-Piquard, R., Sévalle, J., Vincent, B., Boyer, N., Kawarai, T., Girardot, N., St George-Hyslop, P., and Checler, F. (2006) Presenilin-dependent γ-secretase-mediated control of p53-associated cell death in Alzheimer's disease. J. Neurosci. 26, 6377-6385
-
(2006)
J. Neurosci.
, vol.26
, pp. 6377-6385
-
-
Alves Da Costa, C.1
Sunyach, C.2
Pardossi-Piquard, R.3
Sévalle, J.4
Vincent, B.5
Boyer, N.6
Kawarai, T.7
Girardot, N.8
St George-Hyslop, P.9
Checler, F.10
-
27
-
-
0037041426
-
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
-
DOI 10.1038/416535a
-
Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., and Selkoe, D. J. (2002) Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416, 535-539 (Pubitemid 34288854)
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
28
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate, A., Chartier-Harlin, M. C., Mullan, M., Brown, J., Crawford, F., Fidani, L., Giuffra, L., Haynes, A., Irving, N., and James, L. (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349, 704-706 (Pubitemid 21912142)
-
(1991)
Nature
, vol.349
, Issue.6311
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.-C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fldani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
29
-
-
0036932412
-
Solution studies and structural model of the extracellular domain of the human amyloid precursor protein
-
Gralle, M., Botelho, M. M., de Oliveira, C. L., Torriani, I., and Ferreira, S. T. (2002) Solution studies and structural model of the extracellular domain of the human amyloid precursor protein. Biophys. J. 83, 3513-3524 (Pubitemid 36041968)
-
(2002)
Biophysical Journal
, vol.83
, Issue.6
, pp. 3513-3524
-
-
Gralle, M.1
Botelho, M.M.2
De Oliveira, C.L.P.3
Torriani, I.4
Ferreira, S.T.5
-
30
-
-
0031194489
-
Expression of human amyloid precursor protein ectodomains in pichia pastoris: Analysis of culture conditions, purification, and characterization
-
DOI 10.1006/prep.1997.0748
-
Henry, A., Masters, C. L., Beyreuther, K., and Cappai, R. (1997) Expression of human amyloid precursor protein ectodomains in Pichia pastoris: analysis of culture conditions, purification, and characterization. Protein Expr. Purif. 10, 283-291 (Pubitemid 27288793)
-
(1997)
Protein Expression and Purification
, vol.10
, Issue.2
, pp. 283-291
-
-
Henry, A.1
Masters, C.L.2
Beyreuther, K.3
Cappai, R.4
-
31
-
-
67449110951
-
Pharmacological evidences for DFK167-sensitive presenilin-independent γ-secretase-like activity
-
Sevalle, J., Ayral, E., Hernandez, J. F., Martinez, J., and Checler, F. (2009) Pharmacological evidences for DFK167-sensitive presenilin-independent γ-secretase-like activity. J. Neurochem. 110, 275-283
-
(2009)
J. Neurochem.
, vol.110
, pp. 275-283
-
-
Sevalle, J.1
Ayral, E.2
Hernandez, J.F.3
Martinez, J.4
Checler, F.5
-
32
-
-
84934441666
-
Isolation of low-n amyloid β-protein oligomers from cultured cells, CSF, and brain
-
Shankar, G. M., Welzel, A. T., McDonald, J. M., Selkoe, D. J., and Walsh, D. M. (2011) Isolation of low-n amyloid β-protein oligomers from cultured cells, CSF, and brain. Methods Mol. Biol. 670, 33-44
-
(2011)
Methods Mol. Biol.
, vol.670
, pp. 33-44
-
-
Shankar, G.M.1
Welzel, A.T.2
McDonald, J.M.3
Selkoe, D.J.4
Walsh, D.M.5
-
33
-
-
14444267540
-
Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid β peptides: Their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiopathy cases
-
Barelli, H., Lebeau, A., Vizzavona, J., Delaere, P., Chevallier, N., Drouot, C., Marambaud, P., Ancolio, K., Buxbaum, J. D., Khorkova, O., Heroux, J., Sahasrabudhe, S., Martinez, J., Warter, J. M., Mohr, M., and Checler, F. (1997) Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid β peptides: their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiopathy cases. Mol. Med. 3, 695-707 (Pubitemid 28008375)
-
(1997)
Molecular Medicine
, vol.3
, Issue.10
, pp. 695-707
-
-
Barelli, H.1
Lebeau, A.2
Vizzavona, J.3
Delaere, P.4
Chevallier, N.5
Drouot, C.6
Marambaud, P.7
Ancolio, K.8
Buxbaum, J.D.9
Khorkova, O.10
Heroux, J.11
Sahasrabudhe, S.12
Martinez, J.13
Warter, J.-M.14
Mohr, M.15
Checler, F.16
-
34
-
-
15844425969
-
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo
-
DOI 10.1016/S0896-6273(00)80291-3
-
Thinakaran, G., Borchelt, D. R., Lee, M. K., Slunt, H. H., Spitzer, L., Kim, G., Ratovitsky, T., Davenport, F., Nordstedt, C., Seeger, M., Hardy, J., Levey, A. I., Gandy, S. E., Jenkins, N. A., Copeland, N. G., Price, D. L., and Sisodia, S. S. (1996) Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron 17, 181-190 (Pubitemid 26251602)
-
(1996)
Neuron
, vol.17
, Issue.1
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.R.2
Lee, M.K.3
Slunt, H.H.4
Spitzer, L.5
Kim, G.6
Ratovitsky, T.7
Davenport, F.8
Nordstedt, C.9
Seeger, M.10
Hardy, J.11
Levey, A.I.12
Gandy, S.E.13
Jenkins, N.A.14
Copeland, N.G.15
Price, D.L.16
Sisodia, S.S.17
-
35
-
-
0037830752
-
BACE1- and BACE2-expressing human cells: Characterization of β-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in vitro inhibitors
-
DOI 10.1074/jbc.M302622200
-
Andrau, D., Dumanchin-Njock, C., Ayral, E., Vizzavona, J., Farzan, M., Boisbrun, M., Fulcrand, P., Hernandez, J. F., Martinez, J., Lefranc-Jullien, S., and Checler, F. (2003) BACE1- and BACE2-expressing human cells: characterization of β-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in vitro inhibitors. J. Biol. Chem. 278, 25859-25866 (Pubitemid 36835346)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.28
, pp. 25859-25866
-
-
Andrau, D.1
Dumanchin-Njock, C.2
Ayral, E.3
Vizzavona, J.4
Farzan, M.5
Boisbrun, M.6
Fulcrand, P.7
Hernandez, J.-F.8
Martinez, J.9
Lefranc-Jullien, S.10
Checler, F.11
-
36
-
-
19944364907
-
Design and characterization of a new cell-permeant inhibitor of the β-secretase BACE1
-
DOI 10.1038/sj.bjp.0706183
-
Lefranc-Jullien, S., Lisowski, V., Hernandez, J. F., Martinez, J., and Checler, F. (2005) Design and characterization of a new cell-permeant inhibitor of the β-secretase BACE1. Br. J. Pharmacol. 145, 228-235 (Pubitemid 40756527)
-
(2005)
British Journal of Pharmacology
, vol.145
, Issue.2
, pp. 228-235
-
-
Lefranc-Jullien, S.1
Lisowski, V.2
Hernandez, J.-F.3
Martinez, J.4
Checler, F.5
-
37
-
-
0034604583
-
Wild-type but not Parkinson's disease-related Ala-53 → Thr mutant α-Synuclein protects neuronal cells from apoptotic stimuli
-
DOI 10.1074/jbc.M002413200
-
da Costa, C. A., Ancolio, K., and Checler, F. (2000) Wild-type but not Parkinson's disease-related Ala-53 → Thr mutant α-synuclein protects neuronal cells from apoptotic stimuli. J. Biol. Chem. 275, 24065-24069 (Pubitemid 30624697)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.31
, pp. 24065-24069
-
-
Da, C.C.A.1
Ancolio, K.2
Checler, F.3
-
38
-
-
0037133649
-
Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons
-
DOI 10.1073/pnas.062059899
-
Alves da Costa, C., Paitel, E., Mattson, M. P., Amson, R., Telerman, A., Ancolio, K., and Checler, F. (2002) Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons. Proc. Natl. Acad. Sci. U.S.A. 99, 4043-4048 (Pubitemid 34252226)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.6
, pp. 4043-4048
-
-
Alves, D.C.C.1
Paitel, E.2
Mattson, M.P.3
Amson, R.4
Telerman, A.5
Ancolio, K.6
Checler, F.7
-
39
-
-
0347683432
-
Primary Cultured Neurons Devoid of Cellular Prion Display Lower Responsiveness to Staurosporine through the Control of p53 at Both Transcriptional and Post-transcriptional Levels
-
DOI 10.1074/jbc.M310453200
-
Paitel, E., Sunyach, C., Alves da Costa, C., Bourdon, J. C., Vincent, B., and Checler, F. (2004) Primary cultured neurons devoid of cellular prion display lower responsiveness to staurosporine through the control of p53 at both transcriptional and post-transcriptional levels. J. Biol. Chem. 279, 612-618 (Pubitemid 38044865)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.1
, pp. 612-618
-
-
Paitel, E.1
Sunyach, C.2
Da, C.C.A.3
Bourdon, J.-C.4
Vincent, B.5
Checler, F.6
-
40
-
-
33847299070
-
The C-terminal products of cellular prion protein processing, C1 and C2, exert distinct influence on p53-dependent staurosporine-induced caspase-3 activation
-
DOI 10.1074/jbc.M609663200
-
Sunyach, C., Cisse, M. A., da Costa, C. A., Vincent, B., and Checler, F. (2007) The C-terminal products of cellular prion protein processing, C1 and C2, exert distinct influence on p53-dependent staurosporine-induced caspase-3 activation. J. Biol. Chem. 282, 1956-1963 (Pubitemid 47076732)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.3
, pp. 1956-1963
-
-
Sunyach, C.1
Cisse, M.A.2
Da, C.C.A.3
Vincent, B.4
Checler, F.5
-
41
-
-
0033595020
-
Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis
-
DOI 10.1073/pnas.96.13.7547
-
Xu, X., Yang, D., Wyss-Coray, T., Yan, J., Gan, L., Sun, Y., and Mucke, L. (1999) Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis. Proc. Natl. Acad. Sci. U.S.A. 96, 7547-7552 (Pubitemid 29299699)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.13
, pp. 7547-7552
-
-
Xu, X.1
Yang, D.2
Wyss-Coray, T.3
Yan, J.4
Gan, L.5
Sun, Y.6
Mucke, L.7
-
42
-
-
16044373524
-
Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
DOI 10.1038/nm0896-864
-
Scheuner, D., Eckman, C., Jensen, M., Song, X., Citron, M., Suzuki, N., Bird, T. D., Hardy, J., Hutton, M., Kukull, W., Larson, E., Levy-Lahad, E., Viitanen, M., Peskind, E., Poorkaj, P., Schellenberg, G., Tanzi, R., Wasco, W., Lannfelt, L., Selkoe, D., and Younkin, S. (1996) Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 2, 864-870 (Pubitemid 26296755)
-
(1996)
Nature Medicine
, vol.2
, Issue.8
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
43
-
-
33846953615
-
The low-density lipoprotein receptor-related protein 1 (LRP1) mediates the endocytosis of the cellular prion protein
-
Taylor, D. R., and Hooper, N. M. (2007) The low-density lipoprotein receptor-related protein 1 (LRP1) mediates the endocytosis of the cellular prion protein. Biochem. J. 402, 17-23
-
(2007)
Biochem. J.
, vol.402
, pp. 17-23
-
-
Taylor, D.R.1
Hooper, N.M.2
-
44
-
-
42549136005
-
LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein
-
DOI 10.1242/jcs.021816
-
Parkyn, C. J., Vermeulen, E. G., Mootoosamy, R. C., Sunyach, C., Jacobsen, C., Oxvig, C., Moestrup, S., Liu, Q., Bu, G., Jen, A., and Morris, R. J. (2008) LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein. J. Cell Sci. 121, 773-783 (Pubitemid 351578113)
-
(2008)
Journal of Cell Science
, vol.121
, Issue.6
, pp. 773-783
-
-
Parkyn, C.J.1
Vermeulen, E.G.M.2
Mootoosamy, R.C.3
Sunyach, C.4
Jacobsen, C.5
Oxvig, C.6
Moestrup, S.7
Liu, Q.8
Bu, G.9
Jen, A.10
Morris, R.J.11
-
45
-
-
71749107981
-
Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway
-
Fuentealba, R. A., Liu, Q., Kanekiyo, T., Zhang, J., and Bu, G. (2009) Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway. J. Biol. Chem. 284, 34045-34053
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 34045-34053
-
-
Fuentealba, R.A.1
Liu, Q.2
Kanekiyo, T.3
Zhang, J.4
Bu, G.5
-
46
-
-
2942604376
-
The γ-secretase complex: Machinery for intramembrane proteolysis
-
Iwatsubo, T. (2004) The γ-secretase complex: machinery for intramembrane proteolysis. Curr. Opin. Neurobiol. 14, 379-383
-
(2004)
Curr. Opin. Neurobiol.
, vol.14
, pp. 379-383
-
-
Iwatsubo, T.1
-
47
-
-
61849084232
-
Aminopeptidase A contributes to the N-terminal truncation of amyloid β-peptide
-
Sevalle, J., Amoyel, A., Robert, P., Fournié-Zaluski, M. C., Roques, B., and Checler, F. (2009) Aminopeptidase A contributes to the N-terminal truncation of amyloid β-peptide. J. Neurochem. 109, 248-256
-
(2009)
J. Neurochem.
, vol.109
, pp. 248-256
-
-
Sevalle, J.1
Amoyel, A.2
Robert, P.3
Fournié-Zaluski, M.C.4
Roques, B.5
Checler, F.6
-
48
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
DOI 10.1073/pnas.96.6.3228
-
Hsia, A. Y., Masliah, E., McConlogue, L., Yu, G. Q., Tatsuno, G., Hu, K., Kholodenko, D., Malenka, R. C., Nicoll, R. A., and Mucke, L. (1999) Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc. Natl. Acad. Sci. U.S.A. 96, 3228-3233 (Pubitemid 29148873)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.6
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
Mcconlogue, L.3
Yu, G.-Q.4
Tatsuno, G.5
Hu, K.6
Kholodenko, D.7
Malenka, R.C.8
Nicoll, R.A.9
Mucke, L.10
-
49
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Aβ1-42 are potent central nervous system neurotoxins
-
Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., Wals, P., Zhang, C., Finch, C. E., Krafft, G. A., and Klein, W. L. (1998) Diffusible, nonfibrillar ligands derived from Aβ1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. U.S.A. 95, 6448-6453
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
50
-
-
82355192272
-
The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease
-
Ferreira, S. T., and Klein, W. L. (2011) The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease. Neurobiol. Learn. Mem. 96, 529-543
-
(2011)
Neurobiol. Learn. Mem.
, vol.96
, pp. 529-543
-
-
Ferreira, S.T.1
Klein, W.L.2
-
51
-
-
34248190279
-
Aβ oligomers - A decade of discovery
-
Walsh, D. M., and Selkoe, D. J. (2007) Aβ oligomers - a decade of discovery. J. Neurochem. 101, 1172-1184
-
(2007)
J. Neurochem.
, vol.101
, pp. 1172-1184
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
52
-
-
0037017399
-
1-42 through p53 and Bax in cultured primary human neurons
-
DOI 10.1083/jcb.200110119
-
Zhang, Y., McLaughlin, R., Goodyer, C., and LeBlanc, A. (2002) Selective cytotoxicity of intracellular amyloid β peptide1-42 through p53 and Bax in cultured primary human neurons. J. Cell Biol. 156, 519-529 (Pubitemid 34839899)
-
(2002)
Journal of Cell Biology
, vol.156
, Issue.3
, pp. 519-529
-
-
Zhang, Y.1
McLaughlin, R.2
Goodyer, C.3
LeBlanc, A.4
-
53
-
-
69749122264
-
Evidence of molecular links between PKR and mTOR signalling pathways in Aβ neurotoxicity: Role of p53, Redd1 and TSC2
-
Morel, M., Couturier, J., Pontcharraud, R., Gil, R., Fauconneau, B., Paccalin, M., and Page, G. (2009) Evidence of molecular links between PKR and mTOR signalling pathways in Aβ neurotoxicity: role of p53, Redd1 and TSC2. Neurobiol. Dis. 36, 151-161
-
(2009)
Neurobiol. Dis.
, vol.36
, pp. 151-161
-
-
Morel, M.1
Couturier, J.2
Pontcharraud, R.3
Gil, R.4
Fauconneau, B.5
Paccalin, M.6
Page, G.7
-
54
-
-
65549127760
-
Increase in p53 protein levels by presenilin 1 gene mutations and its inhibition by secretase inhibitors
-
Ma, L., Ohyagi, Y., Miyoshi, K., Sakae, N., Motomura, K., Taniwaki, T., Furuya, H., Takeda, K., Tabira, T., and Kira, J. (2009) Increase in p53 protein levels by presenilin 1 gene mutations and its inhibition by secretase inhibitors. J. Alzheimers Dis. 16, 565-575
-
(2009)
J. Alzheimers Dis.
, vol.16
, pp. 565-575
-
-
Ma, L.1
Ohyagi, Y.2
Miyoshi, K.3
Sakae, N.4
Motomura, K.5
Taniwaki, T.6
Furuya, H.7
Takeda, K.8
Tabira, T.9
Kira, J.10
-
55
-
-
0036285116
-
Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein
-
DOI 10.1006/exnr.2002.7920
-
Cheng, G., Yu, Z., Zhou, D., and Mattson, M. P. (2002) Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein. Exp. Neurol. 175, 407-414 (Pubitemid 34634294)
-
(2002)
Experimental Neurology
, vol.175
, Issue.2
, pp. 407-414
-
-
Cheng, G.1
Yu, Z.2
Zhou, D.3
Mattson, M.P.4
-
56
-
-
79956320988
-
Age-dependent accumulation of soluble amyloid β (Aβ) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-α (sAPPα) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK- 3β pathway in Alzheimer mouse model
-
Jimenez, S., Torres, M., Vizuete, M., Sanchez-Varo, R., Sanchez-Mejias, E., Trujillo-Estrada, L., Carmona-Cuenca, I., Caballero, C., Ruano, D., Gutierrez, A., and Vitorica, J. (2011) Age-dependent accumulation of soluble amyloid β (Aβ) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-α (sAPPα) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3β pathway in Alzheimer mouse model. J. Biol. Chem. 286, 18414-18425
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 18414-18425
-
-
Jimenez, S.1
Torres, M.2
Vizuete, M.3
Sanchez-Varo, R.4
Sanchez-Mejias, E.5
Trujillo-Estrada, L.6
Carmona-Cuenca, I.7
Caballero, C.8
Ruano, D.9
Gutierrez, A.10
Vitorica, J.11
-
57
-
-
0029128232
-
LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation
-
Kounnas, M. Z., Moir, R. D., Rebeck, G. W., Bush, A. I., Argraves, W. S., Tanzi, R. E., Hyman, B. T., and Strickland, D. K. (1995) LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation. Cell 82, 331-340
-
(1995)
Cell
, vol.82
, pp. 331-340
-
-
Kounnas, M.Z.1
Moir, R.D.2
Rebeck, G.W.3
Bush, A.I.4
Argraves, W.S.5
Tanzi, R.E.6
Hyman, B.T.7
Strickland, D.K.8
-
58
-
-
49149124343
-
Amyloid-βprotein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar, G. M., Li, S., Mehta, T. H., Garcia-Munoz, A., Shepardson, N. E., Smith, I., Brett, F. M., Farrell, M. A., Rowan, M. J., Lemere, C. A., Regan, C. M., Walsh, D. M., Sabatini, B. L., and Selkoe, D. J. (2008) Amyloid-βprotein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat. Med. 14, 837-842
-
(2008)
Nat. Med.
, vol.14
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
Brett, F.M.7
Farrell, M.A.8
Rowan, M.J.9
Lemere, C.A.10
Regan, C.M.11
Walsh, D.M.12
Sabatini, B.L.13
Selkoe, D.J.14
-
59
-
-
61349201380
-
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers
-
Laurén, J., Gimbel, D. A., Nygaard, H. B., Gilbert, J. W., and Strittmatter, S. M. (2009) Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers. Nature 457, 1128-1132
-
(2009)
Nature
, vol.457
, pp. 1128-1132
-
-
Laurén, J.1
Gimbel, D.A.2
Nygaard, H.B.3
Gilbert, J.W.4
Strittmatter, S.M.5
-
60
-
-
70449629657
-
Cellular prion protein mediates the toxicity of β-amyloid oligomers: Implications for Alzheimer disease
-
Nygaard, H. B., and Strittmatter, S. M. (2009) Cellular prion protein mediates the toxicity of β-amyloid oligomers: implications for Alzheimer disease. Arch. Neurol. 66, 1325-1328
-
(2009)
Arch. Neurol.
, vol.66
, pp. 1325-1328
-
-
Nygaard, H.B.1
Strittmatter, S.M.2
-
61
-
-
77956965281
-
Prion protein in Alzheimer's pathogenesis: A hot and controversial issue
-
Benilova, I., and De Strooper, B. (2010) Prion protein in Alzheimer's pathogenesis: a hot and controversial issue. EMBO Mol. Med. 2, 289-290
-
(2010)
EMBO Mol. Med.
, vol.2
, pp. 289-290
-
-
Benilova, I.1
De Strooper, B.2
-
62
-
-
77956165325
-
Prion protein and Aβ-related synaptic toxicity impairment
-
Calella, A. M., Farinelli, M., Nuvolone, M., Mirante, O., Moos, R., Falsig, J., Mansuy, I. M., and Aguzzi, A. (2010) Prion protein and Aβ-related synaptic toxicity impairment. EMBO Mol. Med. 2, 306-314
-
(2010)
EMBO Mol. Med.
, vol.2
, pp. 306-314
-
-
Calella, A.M.1
Farinelli, M.2
Nuvolone, M.3
Mirante, O.4
Moos, R.5
Falsig, J.6
Mansuy, I.M.7
Aguzzi, A.8
-
63
-
-
79960660843
-
Ablation of cellular prion protein does not ameliorate abnormal neural network activity or cognitive dysfunction in the J20 line of human amyloid precursor protein transgenic mice
-
Cissé, M., Sanchez, P. E., Kim, D. H., Ho, K., Yu, G. Q., and Mucke, L. (2011) Ablation of cellular prion protein does not ameliorate abnormal neural network activity or cognitive dysfunction in the J20 line of human amyloid precursor protein transgenic mice. J. Neurosci. 31, 10427-10431
-
(2011)
J. Neurosci.
, vol.31
, pp. 10427-10431
-
-
Cissé, M.1
Sanchez, P.E.2
Kim, D.H.3
Ho, K.4
Yu, G.Q.5
Mucke, L.6
-
64
-
-
77955617917
-
The prion protein as a receptor for amyloid-β
-
discussion E4-E5
-
Kessels, H. W., Nguyen, L. N., Nabavi, S., and Malinow, R. (2010) The prion protein as a receptor for amyloid-β. Nature 466, E3-E4; discussion E4-E5
-
(2010)
Nature
, vol.466
-
-
Kessels, H.W.1
Nguyen, L.N.2
Nabavi, S.3
Malinow, R.4
-
65
-
-
77956197815
-
Interaction between human prion protein and amyloid-β (Aβ) oligomers: Role of N-terminal residues
-
Chen, S., Yadav, S. P., and Surewicz, W. K. (2010) Interaction between human prion protein and amyloid-β (Aβ) oligomers: role of N-terminal residues. J. Biol. Chem. 285, 26377-26383
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 26377-26383
-
-
Chen, S.1
Yadav, S.P.2
Surewicz, W.K.3
-
66
-
-
79954420180
-
Amyloid-β oligomers increase the localization of prion protein at the cell surface
-
Caetano, F. A., Beraldo, F. H., Hajj, G. N., Guimaraes, A. L., Jürgensen, S., Wasilewska-Sampaio, A. P., Hirata, P. H., Souza, I., Machado, C. F., Wong, D. Y., De Felice, F. G., Ferreira, S. T., Prado, V. F., Rylett, R. J., Martins, V. R., and Prado, M. A. (2011) Amyloid-β oligomers increase the localization of prion protein at the cell surface. J. Neurochem. 117, 538-553
-
(2011)
J. Neurochem.
, vol.117
, pp. 538-553
-
-
Caetano, F.A.1
Beraldo, F.H.2
Hajj, G.N.3
Guimaraes, A.L.4
Jürgensen, S.5
Wasilewska-Sampaio, A.P.6
Hirata, P.H.7
Souza, I.8
Machado, C.F.9
Wong, D.Y.10
De Felice, F.G.11
Ferreira, S.T.12
Prado, V.F.13
Rylett, R.J.14
Martins, V.R.15
Prado, M.A.16
-
67
-
-
33344458827
-
M1 receptors play a central role in modulating AD-like pathology in transgenic mice
-
DOI 10.1016/j.neuron.2006.01.020, PII S0896627306000730
-
Caccamo, A., Oddo, S., Billings, L. M., Green, K. N., Martinez-Coria, H., Fisher, A., and LaFerla, F. M. (2006) M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Neuron 49, 671-682 (Pubitemid 43290127)
-
(2006)
Neuron
, vol.49
, Issue.5
, pp. 671-682
-
-
Caccamo, A.1
Oddo, S.2
Billings, L.M.3
Green, K.N.4
Martinez-Coria, H.5
Fisher, A.6
LaFerla, F.M.7
-
68
-
-
3342934646
-
Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice
-
DOI 10.1073/pnas.0403921101
-
Etcheberrigaray, R., Tan, M., Dewachter, I., Kuipéri, C., Van der Auwera, I., Wera, S., Qiao, L., Bank, B., Nelson, T. J., Kozikowski, A. P., Van Leuven, F., and Alkon, D. L. (2004) Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice. Proc. Natl. Acad. Sci. U.S.A. 101, 11141-11146 (Pubitemid 38989597)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.30
, pp. 11141-11146
-
-
Etcheberrigaray, R.1
Tan, M.2
Dewachtert, I.3
Kuiperi, C.4
Van Der, A.I.5
Wera, S.6
Qiao, L.7
Bank, B.8
Nelson, T.J.9
Kozikowski, A.P.10
Van Leuven, F.11
Alkon, D.L.12
-
69
-
-
85047690140
-
A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alheizmer disease mouse model
-
DOI 10.1172/JCI200420864
-
Postina, R., Schroeder, A., Dewachter, I., Bohl, J., Schmitt, U., Kojro, E., Prinzen, C., Endres, K., Hiemke, C., Blessing, M., Flamez, P., Dequenne, A., Godaux, E., van Leuven, F., and Fahrenholz, F. (2004) A disintegrin- metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model. J. Clin. Investig. 113, 1456-1464 (Pubitemid 39071701)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.10
, pp. 1456-1464
-
-
Postina, R.1
Schroeder, A.2
Dewachter, I.3
Bohl, J.4
Schmitt, U.5
Kojro, E.6
Prinzen, C.7
Endres, K.8
Hiemke, C.9
Blessing, M.10
Flamez, P.11
Dequenne, A.12
Godaux, E.13
Van Leuven, F.14
Fahrenholz, F.15
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