Give it or take it: the flux of one-carbon in cancer cells

FEBS Journal

Volumn 283, Issue 20, 2016, Pages 3695-3704

  Meiser, Johannes ^a   Vazquez, Alexei ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

cancer metabolism; cell growth; folate metabolism; mitochondria metabolism; one carbon metabolism

Indexed keywords

2 HYDROXYGLUTARIC ACID; 2 OXOGLUTARIC ACID; ADENYLATE KINASE; DIHYDROFOLATE REDUCTASE; ISOCITRATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE 1; METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE; PROTEIN FTHFS; PROTEIN MTHFD2; PROTEIN MTHFD2L; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THYMIDYLATE SYNTHASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; CARBON; GLYCINE; SERINE;

BIOSYNTHESIS; CANCER CELL; CANCER GENETICS; CARBON METABOLISM; CELL COMPARTMENTALIZATION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; ENZYME SYNTHESIS; GENE EXPRESSION; GLYCOLYSIS; HUMAN; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN METHYLATION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CARBON CYCLE; CYTOSOL; EMBRYO DEVELOPMENT; METABOLISM; METHYLATION; MITOCHONDRION; NEOPLASM;

ANIMALS; CARBON; CARBON CYCLE; CELL COMPARTMENTATION; CYTOSOL; EMBRYONIC DEVELOPMENT; GLYCINE; HUMANS; METABOLIC NETWORKS AND PATHWAYS; METHYLATION; MITOCHONDRIA; MODELS, BIOLOGICAL; NEOPLASMS; SERINE;

EID: 84964612429     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.13731     Document Type: Review

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