SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis

PLoS ONE

Volumn 4, Issue 6, 2009, Pages

  Anderson, Donald D ^a   Stover, Patrick J ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOMETHYLPHOSPHONIC ACID; DIHYDROFOLATE REDUCTASE; GLYCINE; GLYCINE HYDROXYMETHYLTRANSFERASE; GLYCINE HYDROXYMETHYLTRANSFERASE 1; GLYCINE HYDROXYMETHYLTRANSFERASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SERINE; THYMIDINE PHOSPHATE; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG; URIDINE PHOSPHATE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PYRIMIDINE NUCLEOTIDE; SHMT1 PROTEIN, HUMAN; THYMIDINE 5'-TRIPHOSPHATE; THYMIDINE TRIPHOSPHATE;

ANIMAL CELL; ARTICLE; AUXOTROPHY; CELL CYCLE S PHASE; CHO CELL; CONTROLLED STUDY; CYTOPLASM; EMBRYO; ENZYME SYNTHESIS; EXON; GENE EXPRESSION; GENE LOCATION; HUMAN; HUMAN CELL; LIVER CELL NUCLEUS; LIVER MITOCHONDRION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SUMOYLATION; AMINO ACID SEQUENCE; ANIMAL; CELL NUCLEUS; CELL STRAIN 3T3; CHEMISTRY; CRICETULUS; HAMSTER; HELA CELL; LIVER; METABOLISM; MOLECULAR GENETICS;

MAMMALIA; MUS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL NUCLEUS; CHO CELLS; CRICETINAE; CRICETULUS; GLYCINE HYDROXYMETHYLTRANSFERASE; HELA CELLS; HUMANS; LIVER; MICE; MOLECULAR SEQUENCE DATA; NADP; NIH 3T3 CELLS; SERINE; TETRAHYDROFOLATE DEHYDROGENASE; THYMINE NUCLEOTIDES;

EID: 67649225407     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005839     Document Type: Article

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