Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 37, 2011, Pages 15163-15168

  Andersona, Donald D ^a   Quintero, Cynthia M ^a   Stovera, Patrick J ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Deoxyribouridine; Folate; One carbon metabolism; Thymidine

Indexed keywords

DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE REDUCTASE LIKE PROTEIN 1; GLYCINE HYDROXYMETHYLTRANSFERASE; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SERINE; THYMIDINE PHOSPHATE; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE INACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRION; NONHUMAN; OVARY CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BIOSYNTHETIC PATHWAYS; CHO CELLS; CRICETINAE; CRICETULUS; DNA, MITOCHONDRIAL; GENE EXPRESSION REGULATION; GLYCINE; HUMANS; MAMMALS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; TETRAHYDROFOLATE DEHYDROGENASE; THYMIDINE MONOPHOSPHATE; THYMIDYLATE SYNTHASE; THYMINE NUCLEOTIDES; URACIL;

CRICETULUS GRISEUS; MAMMALIA;

EID: 80053089625     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1103623108     Document Type: Article

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