-
1
-
-
84872555329
-
Circulating histones are mediators of trauma-associated lung injury
-
Abrams, S.T., Zhang, N., Manson, J., Liu, T., Dart, C., Baluwa, F., Wang, S.S., Brohi, K., Kipar, A., Yu, W., Wang, G. & Toh, C.H. (2013a) Circulating histones are mediators of trauma-associated lung injury. American Journal of Respiratory and Critical Care Medicine, 187, 160-169.
-
(2013)
American Journal of Respiratory and Critical Care Medicine
, vol.187
, pp. 160-169
-
-
Abrams, S.T.1
Zhang, N.2
Manson, J.3
Liu, T.4
Dart, C.5
Baluwa, F.6
Wang, S.S.7
Brohi, K.8
Kipar, A.9
Yu, W.10
Wang, G.11
Toh, C.H.12
-
2
-
-
84883317004
-
Human CRP defends against the toxicity of circulating histones
-
Abrams, S.T., Zhang, N., Dart, C., Wang, S.S., Thachil, J., Guan, Y., Wang, G. & Toh, C.H. (2013b) Human CRP defends against the toxicity of circulating histones. Journal of Immunology, 191, 2495-2502.
-
(2013)
Journal of Immunology
, vol.191
, pp. 2495-2502
-
-
Abrams, S.T.1
Zhang, N.2
Dart, C.3
Wang, S.S.4
Thachil, J.5
Guan, Y.6
Wang, G.7
Toh, C.H.8
-
3
-
-
84941924101
-
Circulating histones are major mediators of cardiac injury in patients with sepsis
-
Alhamdi, Y., Abrams, S.T., Cheng, Z., Jing, S., Su, D., Liu, Z., Lane, S., Welters, I., Wang, G. & Toh, C.H. (2015) Circulating histones are major mediators of cardiac injury in patients with sepsis. Critical Care Medicine, 43, 2094-2103.
-
(2015)
Critical Care Medicine
, vol.43
, pp. 2094-2103
-
-
Alhamdi, Y.1
Abrams, S.T.2
Cheng, Z.3
Jing, S.4
Su, D.5
Liu, Z.6
Lane, S.7
Welters, I.8
Wang, G.9
Toh, C.H.10
-
4
-
-
84947727115
-
Circulating histone concentrations differentially affect the predominance of left or right ventricular dysfunction in critical illness
-
Alhamdi, Y., Zi, M., Abrams, S.T., Liu, T., Su, D., Welters, I., Dutt, T., Cartwright, E.J., Wang, G. & Toh, C.H. (2016a) Circulating histone concentrations differentially affect the predominance of left or right ventricular dysfunction in critical illness. Critical Care Medicine, 44, e278-e288.
-
(2016)
Critical Care Medicine
, vol.44
, pp. e278-e288
-
-
Alhamdi, Y.1
Zi, M.2
Abrams, S.T.3
Liu, T.4
Su, D.5
Welters, I.6
Dutt, T.7
Cartwright, E.J.8
Wang, G.9
Toh, C.H.10
-
5
-
-
84959264967
-
Histone-associated thrombocytopenia in patients who are critically ill
-
Alhamdi, Y., Abrams, S.T., Lane, S., Wang, G. & Toh, C.H. (2016b) Histone-associated thrombocytopenia in patients who are critically ill. JAMA: The Journal of the American Medical Association, 315, 817-819.
-
(2016)
JAMA: The Journal of the American Medical Association
, vol.315
, pp. 817-819
-
-
Alhamdi, Y.1
Abrams, S.T.2
Lane, S.3
Wang, G.4
Toh, C.H.5
-
6
-
-
84864849535
-
Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4
-
Allam, R., Scherbaum, C.R., Darisipudi, M.N., Mulay, S.R., Hagele, H., Lichtnekert, J., Hagemann, J.H., Rupanagudi, K.V., Ryu, M., Schwarzenberger, C., Hohenstein, B., Hugo, C., Uhl, B., Reichel, C.A., Krombach, F., Monestier, M., Liapis, H., Moreth, K., Schaefer, L. & Anders, H.J. (2012) Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4. Journal of the American Society of Nephrology: JASN, 23, 1375-1388.
-
(2012)
Journal of the American Society of Nephrology: JASN
, vol.23
, pp. 1375-1388
-
-
Allam, R.1
Scherbaum, C.R.2
Darisipudi, M.N.3
Mulay, S.R.4
Hagele, H.5
Lichtnekert, J.6
Hagemann, J.H.7
Rupanagudi, K.V.8
Ryu, M.9
Schwarzenberger, C.10
Hohenstein, B.11
Hugo, C.12
Uhl, B.13
Reichel, C.A.14
Krombach, F.15
Monestier, M.16
Liapis, H.17
Moreth, K.18
Schaefer, L.19
Anders, H.J.20
more..
-
7
-
-
80052395881
-
Extracellular histones increase plasma thrombin generation by impairing thrombomodulin-dependent protein C activation
-
Ammollo, C.T., Semeraro, F., Xu, J., Esmon, N.L. & Esmon, C.T. (2011) Extracellular histones increase plasma thrombin generation by impairing thrombomodulin-dependent protein C activation. Journal of Thrombosis and Haemostasis: JTH, 9, 1795-1803.
-
(2011)
Journal of Thrombosis and Haemostasis: JTH
, vol.9
, pp. 1795-1803
-
-
Ammollo, C.T.1
Semeraro, F.2
Xu, J.3
Esmon, N.L.4
Esmon, C.T.5
-
8
-
-
84890346744
-
Histone H4 promotes prothrombin autoactivation
-
Barranco-Medina, S., Pozzi, N., Vogt, A.D. & Di Cera, E. (2013) Histone H4 promotes prothrombin autoactivation. The Journal of Biological Chemistry, 288, 35749-35757.
-
(2013)
The Journal of Biological Chemistry
, vol.288
, pp. 35749-35757
-
-
Barranco-Medina, S.1
Pozzi, N.2
Vogt, A.D.3
Di Cera, E.4
-
10
-
-
84890506255
-
Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury
-
Bosmann, M., Grailer, J.J., Ruemmler, R., Russkamp, N.F., Zetoune, F.S., Sarma, J.V., Standiford, T.J. & Ward, P.A. (2013) Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury. The FASEB Journal, 27, 5010-5021.
-
(2013)
The FASEB Journal
, vol.27
, pp. 5010-5021
-
-
Bosmann, M.1
Grailer, J.J.2
Ruemmler, R.3
Russkamp, N.F.4
Zetoune, F.S.5
Sarma, J.V.6
Standiford, T.J.7
Ward, P.A.8
-
11
-
-
84908135568
-
Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens
-
Branzk, N., Lubojemska, A., Hardison, S.E., Wang, Q., Gutierrez, M.G., Brown, G.D. & Papayannopoulos, V. (2014) Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens. Nature Immunology, 15, 1017-1025.
-
(2014)
Nature Immunology
, vol.15
, pp. 1017-1025
-
-
Branzk, N.1
Lubojemska, A.2
Hardison, S.E.3
Wang, Q.4
Gutierrez, M.G.5
Brown, G.D.6
Papayannopoulos, V.7
-
12
-
-
84855414173
-
Neutrophil extracellular traps promote deep vein thrombosis in mice
-
Brill, A., Fuchs, T.A., Savchenko, A.S., Thomas, G.M., Martinod, K., De Meyer, S.F., Bhandari, A.A. & Wagner, D.D. (2012) Neutrophil extracellular traps promote deep vein thrombosis in mice. Journal of Thrombosis and Haemostasis: JTH, 10, 136-144.
-
(2012)
Journal of Thrombosis and Haemostasis: JTH
, vol.10
, pp. 136-144
-
-
Brill, A.1
Fuchs, T.A.2
Savchenko, A.S.3
Thomas, G.M.4
Martinod, K.5
De Meyer, S.F.6
Bhandari, A.A.7
Wagner, D.D.8
-
13
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
Brinkmann, V., Reichard, U., Goosmann, C., Fauler, B., Uhlemann, Y., Weiss, D.S., Weinrauch, Y. & Zychlinsky, A. (2004) Neutrophil extracellular traps kill bacteria. Science, 303, 1532-1535.
-
(2004)
Science
, vol.303
, pp. 1532-1535
-
-
Brinkmann, V.1
Reichard, U.2
Goosmann, C.3
Fauler, B.4
Uhlemann, Y.5
Weiss, D.S.6
Weinrauch, Y.7
Zychlinsky, A.8
-
14
-
-
84863548610
-
Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury
-
Caudrillier, A., Kessenbrock, K., Gilliss, B.M., Nguyen, J.X., Marques, M.B., Monestier, M., Toy, P., Werb, Z. & Looney, M.R. (2012) Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury. Journal of Clinical Investigation, 122, 2661-2671.
-
(2012)
Journal of Clinical Investigation
, vol.122
, pp. 2661-2671
-
-
Caudrillier, A.1
Kessenbrock, K.2
Gilliss, B.M.3
Nguyen, J.X.4
Marques, M.B.5
Monestier, M.6
Toy, P.7
Werb, Z.8
Looney, M.R.9
-
15
-
-
84906859591
-
Release and activity of histone in diseases
-
Chen, R., Kang, R., Fan, X.G. & Tang, D. (2014a) Release and activity of histone in diseases. Cell Death & Disease, 5, e1370.
-
(2014)
Cell Death & Disease
, vol.5
, pp. e1370
-
-
Chen, R.1
Kang, R.2
Fan, X.G.3
Tang, D.4
-
16
-
-
84902585238
-
Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease
-
Chen, G., Zhang, D., Fuchs, T.A., Manwani, D., Wagner, D.D. & Frenette, P.S. (2014b) Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease. Blood, 123, 3818-3827.
-
(2014)
Blood
, vol.123
, pp. 3818-3827
-
-
Chen, G.1
Zhang, D.2
Fuchs, T.A.3
Manwani, D.4
Wagner, D.D.5
Frenette, P.S.6
-
17
-
-
14844307097
-
Epigenetic regulation by histone methylation and histone variants
-
Cheung, P. & Lau, P. (2005) Epigenetic regulation by histone methylation and histone variants. Molecular Endocrinology, 19, 563-573.
-
(2005)
Molecular Endocrinology
, vol.19
, pp. 563-573
-
-
Cheung, P.1
Lau, P.2
-
18
-
-
38949115609
-
The Yin-Yang of thrombin and activated protein C
-
Dutt, T. & Toh, C.H. (2008) The Yin-Yang of thrombin and activated protein C. British Journal of Haematology, 140, 505-515.
-
(2008)
British Journal of Haematology
, vol.140
, pp. 505-515
-
-
Dutt, T.1
Toh, C.H.2
-
19
-
-
84964313704
-
Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation
-
Ekaney, M.L., Otto, G.P., Sossdorf, M., Sponholz, C., Boehringer, M., Loesche, W., Rittirsch, D., Wilharm, A., Kurzai, O., Bauer, M. & Claus, R.A. (2014) Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation. Critical Care, 18, 543.
-
(2014)
Critical Care
, vol.18
, pp. 543
-
-
Ekaney, M.L.1
Otto, G.P.2
Sossdorf, M.3
Sponholz, C.4
Boehringer, M.5
Loesche, W.6
Rittirsch, D.7
Wilharm, A.8
Kurzai, O.9
Bauer, M.10
Claus, R.A.11
-
21
-
-
84919339903
-
Epigenetics in the hematologic malignancies
-
Fong, C.Y., Morison, J. & Dawson, M.A. (2014) Epigenetics in the hematologic malignancies. Haematologica, 99, 1772-1783.
-
(2014)
Haematologica
, vol.99
, pp. 1772-1783
-
-
Fong, C.Y.1
Morison, J.2
Dawson, M.A.3
-
22
-
-
80053354116
-
Histones induce rapid and profound thrombocytopenia in mice
-
Fuchs, T.A., Bhandari, A.A. & Wagner, D.D. (2011) Histones induce rapid and profound thrombocytopenia in mice. Blood, 118, 3708-3714.
-
(2011)
Blood
, vol.118
, pp. 3708-3714
-
-
Fuchs, T.A.1
Bhandari, A.A.2
Wagner, D.D.3
-
23
-
-
0025887849
-
Effect of combinations of cytokines and hormones on synthesis of serum amyloid A and C-reactive protein in Hep 3B cells
-
Ganapathi, M.K., Rzewnicki, D., Samols, D., Jiang, S.L. & Kushner, I. (1991) Effect of combinations of cytokines and hormones on synthesis of serum amyloid A and C-reactive protein in Hep 3B cells. Journal of Immunology, 147, 1261-1265.
-
(1991)
Journal of Immunology
, vol.147
, pp. 1261-1265
-
-
Ganapathi, M.K.1
Rzewnicki, D.2
Samols, D.3
Jiang, S.L.4
Kushner, I.5
-
24
-
-
0030053265
-
Blood clearance kinetics and liver uptake of mononucleosomes in mice
-
Gauthier, V.J., Tyler, L.N. & Mannik, M. (1996) Blood clearance kinetics and liver uptake of mononucleosomes in mice. Journal of Immunology, 156, 1151-1156.
-
(1996)
Journal of Immunology
, vol.156
, pp. 1151-1156
-
-
Gauthier, V.J.1
Tyler, L.N.2
Mannik, M.3
-
25
-
-
84863122657
-
Plasmodium falciparum histones induce endothelial proinflammatory response and barrier dysfunction
-
Gillrie, M.R., Lee, K., Gowda, D.C., Davis, S.P., Monestier, M., Cui, L., Hien, T.T., Day, N.P. & Ho, M. (2012) Plasmodium falciparum histones induce endothelial proinflammatory response and barrier dysfunction. American Journal of Pathology, 180, 1028-1039.
-
(2012)
American Journal of Pathology
, vol.180
, pp. 1028-1039
-
-
Gillrie, M.R.1
Lee, K.2
Gowda, D.C.3
Davis, S.P.4
Monestier, M.5
Cui, L.6
Hien, T.T.7
Day, N.P.8
Ho, M.9
-
26
-
-
80051969149
-
Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice
-
Huang, H., Evankovich, J., Yan, W., Nace, G., Zhang, L., Ross, M., Liao, X., Billiar, T., Xu, J., Esmon, C.T. & Tsung, A. (2011) Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice. Hepatology, 54, 999-1008.
-
(2011)
Hepatology
, vol.54
, pp. 999-1008
-
-
Huang, H.1
Evankovich, J.2
Yan, W.3
Nace, G.4
Zhang, L.5
Ross, M.6
Liao, X.7
Billiar, T.8
Xu, J.9
Esmon, C.T.10
Tsung, A.11
-
27
-
-
84883367417
-
Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury
-
Huang, H., Chen, H.W., Evankovich, J., Yan, W., Rosborough, B.R., Nace, G.W., Ding, Q., Loughran, P., Beer-Stolz, D., Billiar, T.R., Esmon, C.T. & Tsung, A. (2013) Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury. Journal of Immunology, 191, 2665-2679.
-
(2013)
Journal of Immunology
, vol.191
, pp. 2665-2679
-
-
Huang, H.1
Chen, H.W.2
Evankovich, J.3
Yan, W.4
Rosborough, B.R.5
Nace, G.W.6
Ding, Q.7
Loughran, P.8
Beer-Stolz, D.9
Billiar, T.R.10
Esmon, C.T.11
Tsung, A.12
-
28
-
-
84934933688
-
Role of extracellular histones in the cardiomyopathy of sepsis
-
Kalbitz, M., Grailer, J.J., Fattahi, F., Jajou, L., Herron, T.J., Campbell, K.F., Zetoune, F.S., Bosmann, M., Sarma, J.V., Huber-Lang, M., Gebhard, F., Loaiza, R., Valdivia, H.H., Jalife, J., Russell, M.W. & Ward, P.A. (2015) Role of extracellular histones in the cardiomyopathy of sepsis. The FASEB Journal, 29, 2185-2193.
-
(2015)
The FASEB Journal
, vol.29
, pp. 2185-2193
-
-
Kalbitz, M.1
Grailer, J.J.2
Fattahi, F.3
Jajou, L.4
Herron, T.J.5
Campbell, K.F.6
Zetoune, F.S.7
Bosmann, M.8
Sarma, J.V.9
Huber-Lang, M.10
Gebhard, F.11
Loaiza, R.12
Valdivia, H.H.13
Jalife, J.14
Russell, M.W.15
Ward, P.A.16
-
29
-
-
84929507182
-
Circulating levels of DNA-histone complex and dsDNA are independent prognostic factors of disseminated intravascular coagulation
-
Kim, J.E., Lee, N., Gu, J.Y., Yoo, H.J. & Kim, H.K. (2015) Circulating levels of DNA-histone complex and dsDNA are independent prognostic factors of disseminated intravascular coagulation. Thrombosis Research, 135, 1064-1069.
-
(2015)
Thrombosis Research
, vol.135
, pp. 1064-1069
-
-
Kim, J.E.1
Lee, N.2
Gu, J.Y.3
Yoo, H.J.4
Kim, H.K.5
-
30
-
-
84925763736
-
Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature
-
Kolaczkowska, E., Jenne, C.N., Surewaard, B.G., Thanabalasuriar, A., Lee, W.Y., Sanz, M.J., Mowen, K., Opdenakker, G. & Kubes, P. (2015) Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature. Nature Communications, 6, 6673.
-
(2015)
Nature Communications
, vol.6
, pp. 6673
-
-
Kolaczkowska, E.1
Jenne, C.N.2
Surewaard, B.G.3
Thanabalasuriar, A.4
Lee, W.Y.5
Sanz, M.J.6
Mowen, K.7
Opdenakker, G.8
Kubes, P.9
-
31
-
-
84871196677
-
Extracellular histone release in response to traumatic injury: Implications for a compensatory role of activated protein C
-
Kutcher, M.E., Xu, J., Vilardi, R.F., Ho, C., Esmon, C.T. & Cohen, M.J. (2012) Extracellular histone release in response to traumatic injury: Implications for a compensatory role of activated protein C. Journal of Trauma and Acute Care Surgery, 73, 1389-1394.
-
(2012)
Journal of Trauma and Acute Care Surgery
, vol.73
, pp. 1389-1394
-
-
Kutcher, M.E.1
Xu, J.2
Vilardi, R.F.3
Ho, C.4
Esmon, C.T.5
Cohen, M.J.6
-
32
-
-
84969874948
-
Histones stimulate ultra-large von Willebrand factor release from endothelium: A potential contributor to the prothrombotic state in sepsis
-
Supplement 63113
-
Lam, F., Cruz, M., Parikh, K. & Rumbaut, R. (2015) Histones stimulate ultra-large von Willebrand factor release from endothelium: A potential contributor to the prothrombotic state in sepsis. The FASEB Journal, 29, Supplement 631.13.
-
(2015)
The FASEB Journal
, vol.29
-
-
Lam, F.1
Cruz, M.2
Parikh, K.3
Rumbaut, R.4
-
33
-
-
84874869767
-
Mechanical stability and fibrinolytic resistance of clots containing fibrin, DNA, and histones
-
Longstaff, C., Varju, I., Sotonyi, P., Szabo, L., Krumrey, M., Hoell, A., Bota, A., Varga, Z., Komorowicz, E. & Kolev, K. (2013) Mechanical stability and fibrinolytic resistance of clots containing fibrin, DNA, and histones. The Journal of Biological Chemistry, 288, 6946-6956.
-
(2013)
The Journal of Biological Chemistry
, vol.288
, pp. 6946-6956
-
-
Longstaff, C.1
Varju, I.2
Sotonyi, P.3
Szabo, L.4
Krumrey, M.5
Hoell, A.6
Bota, A.7
Varga, Z.8
Komorowicz, E.9
Kolev, K.10
-
34
-
-
84902104685
-
Thrombosis: Tangled up in NETs
-
Martinod, K. & Wagner, D.D. (2014) Thrombosis: Tangled up in NETs. Blood, 123, 2768-2776.
-
(2014)
Blood
, vol.123
, pp. 2768-2776
-
-
Martinod, K.1
Wagner, D.D.2
-
35
-
-
77955410626
-
Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases
-
Massberg, S., Grahl, L., von Bruehl, M.L., Manukyan, D., Pfeiler, S., Goosmann, C., Brinkmann, V., Lorenz, M., Bidzhekov, K., Khandagale, A.B., Konrad, I., Kennerknecht, E., Reges, K., Holdenrieder, S., Braun, S., Reinhardt, C., Spannagl, M., Preissner, K.T. & Engelmann, B. (2010) Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases. Nature Medicine, 16, 887-896.
-
(2010)
Nature Medicine
, vol.16
, pp. 887-896
-
-
Massberg, S.1
Grahl, L.2
von Bruehl, M.L.3
Manukyan, D.4
Pfeiler, S.5
Goosmann, C.6
Brinkmann, V.7
Lorenz, M.8
Bidzhekov, K.9
Khandagale, A.B.10
Konrad, I.11
Kennerknecht, E.12
Reges, K.13
Holdenrieder, S.14
Braun, S.15
Reinhardt, C.16
Spannagl, M.17
Preissner, K.T.18
Engelmann, B.19
-
36
-
-
84871731766
-
Circulating nucleosomes and neutrophil activation as risk factors for deep vein thrombosis
-
van Montfoort, M.L., Stephan, F., Lauw, M.N., Hutten, B.A., Van Mierlo, G.J., Solati, S., Middeldorp, S., Meijers, J.C. & Zeerleder, S. (2013) Circulating nucleosomes and neutrophil activation as risk factors for deep vein thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 33, 147-151.
-
(2013)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.33
, pp. 147-151
-
-
van Montfoort, M.L.1
Stephan, F.2
Lauw, M.N.3
Hutten, B.A.4
Van Mierlo, G.J.5
Solati, S.6
Middeldorp, S.7
Meijers, J.C.8
Zeerleder, S.9
-
37
-
-
84884752631
-
Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism
-
Nakahara, M., Ito, T., Kawahara, K., Yamamoto, M., Nagasato, T., Shrestha, B., Yamada, S., Miyauchi, T., Higuchi, K., Takenaka, T., Yasuda, T., Matsunaga, A., Kakihana, Y., Hashiguchi, T., Kanmura, Y. & Maruyama, I. (2013) Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism. PLoS ONE, 8, e75961.
-
(2013)
PLoS ONE
, vol.8
, pp. e75961
-
-
Nakahara, M.1
Ito, T.2
Kawahara, K.3
Yamamoto, M.4
Nagasato, T.5
Shrestha, B.6
Yamada, S.7
Miyauchi, T.8
Higuchi, K.9
Takenaka, T.10
Yasuda, T.11
Matsunaga, A.12
Kakihana, Y.13
Hashiguchi, T.14
Kanmura, Y.15
Maruyama, I.16
-
38
-
-
84942041575
-
Circulating histone levels reflect disease severity in animal models of acute pancreatitis
-
Ou, X., Cheng, Z., Liu, T., Tang, Z., Huang, W., Szatmary, P., Zheng, S., Sutton, R., Toh, C.H., Zhang, N. & Wang, G. (2015) Circulating histone levels reflect disease severity in animal models of acute pancreatitis. Pancreas, 44, 1089-1095.
-
(2015)
Pancreas
, vol.44
, pp. 1089-1095
-
-
Ou, X.1
Cheng, Z.2
Liu, T.3
Tang, Z.4
Huang, W.5
Szatmary, P.6
Zheng, S.7
Sutton, R.8
Toh, C.H.9
Zhang, N.10
Wang, G.11
-
39
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi, P., Misteli, T. & Bianchi, M.E. (2002) Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature, 418, 191-195.
-
(2002)
Nature
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
40
-
-
84887009674
-
Nucleosomes and neutrophil activation in sickle cell disease painful crisis
-
Curama Study, G.
-
Schimmel, M., Nur, E., Biemond, B.J., van Mierlo, G.J., Solati, S., Brandjes, D.P., Otten, H.M., Schnog, J.J., Zeerleder, S. & Curama Study, G. (2013) Nucleosomes and neutrophil activation in sickle cell disease painful crisis. Haematologica, 98, 1797-1803.
-
(2013)
Haematologica
, vol.98
, pp. 1797-1803
-
-
Schimmel, M.1
Nur, E.2
Biemond, B.J.3
van Mierlo, G.J.4
Solati, S.5
Brandjes, D.P.6
Otten, H.M.7
Schnog, J.J.8
Zeerleder, S.9
-
41
-
-
80051884192
-
Extracellular histones promote thrombin generation through platelet-dependent mechanisms: Involvement of platelet TLR2 and TLR4
-
Semeraro, F., Ammollo, C.T., Morrissey, J.H., Dale, G.L., Friese, P., Esmon, N.L. & Esmon, C.T. (2011) Extracellular histones promote thrombin generation through platelet-dependent mechanisms: Involvement of platelet TLR2 and TLR4. Blood, 118, 1952-1961.
-
(2011)
Blood
, vol.118
, pp. 1952-1961
-
-
Semeraro, F.1
Ammollo, C.T.2
Morrissey, J.H.3
Dale, G.L.4
Friese, P.5
Esmon, N.L.6
Esmon, C.T.7
-
42
-
-
84907864499
-
Histones induce phosphatidylserine exposure and a procoagulant phenotype in human red blood cells
-
Semeraro, F., Ammollo, C.T., Esmon, N.L. & Esmon, C.T. (2014) Histones induce phosphatidylserine exposure and a procoagulant phenotype in human red blood cells. Journal of Thrombosis and Haemostasis: JTH, 12, 1697-1702.
-
(2014)
Journal of Thrombosis and Haemostasis: JTH
, vol.12
, pp. 1697-1702
-
-
Semeraro, F.1
Ammollo, C.T.2
Esmon, N.L.3
Esmon, C.T.4
-
43
-
-
84860475506
-
Factor seven activating protease (FSAP): Does it activate factor VII?
-
Stavenuiter, F., Dienava-Verdoold, I., Boon-Spijker, M.G., Brinkman, H.J., Meijer, A.B. & Mertens, K. (2012) Factor seven activating protease (FSAP): Does it activate factor VII? Journal of Thrombosis and Haemostasis: JTH, 10, 859-866.
-
(2012)
Journal of Thrombosis and Haemostasis: JTH
, vol.10
, pp. 859-866
-
-
Stavenuiter, F.1
Dienava-Verdoold, I.2
Boon-Spijker, M.G.3
Brinkman, H.J.4
Meijer, A.B.5
Mertens, K.6
-
44
-
-
84863502628
-
Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice
-
Thomas, G.M., Carbo, C., Curtis, B.R., Martinod, K., Mazo, I.B., Schatzberg, D., Cifuni, S.M., Fuchs, T.A., von Andrian, U.H., Hartwig, J.H., Aster, R.H. & Wagner, D.D. (2012) Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice. Blood, 119, 6335-6343.
-
(2012)
Blood
, vol.119
, pp. 6335-6343
-
-
Thomas, G.M.1
Carbo, C.2
Curtis, B.R.3
Martinod, K.4
Mazo, I.B.5
Schatzberg, D.6
Cifuni, S.M.7
Fuchs, T.A.8
von Andrian, U.H.9
Hartwig, J.H.10
Aster, R.H.11
Wagner, D.D.12
-
46
-
-
84929304430
-
Polyphosphate, platelets, and coagulation
-
Travers, R.J., Smith, S.A. & Morrissey, J.H. (2015) Polyphosphate, platelets, and coagulation. International Journal of Laboratory Hematology, 37, 31-35.
-
(2015)
International Journal of Laboratory Hematology
, vol.37
, pp. 31-35
-
-
Travers, R.J.1
Smith, S.A.2
Morrissey, J.H.3
-
47
-
-
84866072040
-
Management of thrombocytopenia in the ICU (pregnancy excluded)
-
Van der Linden, T., Souweine, B., Dupic, L., Soufir, L. & Meyer, P. (2012) Management of thrombocytopenia in the ICU (pregnancy excluded). Annals of Intensive Care, 2, 42.
-
(2012)
Annals of Intensive Care
, vol.2
, pp. 42
-
-
Van der Linden, T.1
Souweine, B.2
Dupic, L.3
Soufir, L.4
Meyer, P.5
-
48
-
-
84931281973
-
DNA, histones and neutrophil extracellular traps exert anti-fibrinolytic effects in a plasma environment
-
Varju, I., Longstaff, C., Szabo, L., Farkas, A.Z., Varga-Szabo, V.J., Tanka-Salamon, A., Machovich, R. & Kolev, K. (2015) DNA, histones and neutrophil extracellular traps exert anti-fibrinolytic effects in a plasma environment. Thrombosis and Haemostasis, 113, 1289-1298.
-
(2015)
Thrombosis and Haemostasis
, vol.113
, pp. 1289-1298
-
-
Varju, I.1
Longstaff, C.2
Szabo, L.3
Farkas, A.Z.4
Varga-Szabo, V.J.5
Tanka-Salamon, A.6
Machovich, R.7
Kolev, K.8
-
49
-
-
84883615933
-
A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation
-
Vincent, J.L., Ramesh, M.K., Ernest, D., LaRosa, S.P., Pachl, J., Aikawa, N., Hoste, E., Levy, H., Hirman, J., Levi, M., Daga, M., Kutsogiannis, D.J., Crowther, M., Bernard, G.R., Devriendt, J., Puigserver, J.V., Blanzaco, D.U., Esmon, C.T., Parrillo, J.E., Guzzi, L., Henderson, S.J., Pothirat, C., Mehta, P., Fareed, J., Talwar, D., Tsuruta, K., Gorelick, K.J., Osawa, Y. & Kaul, I. (2013) A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation. Critical Care Medicine, 41, 2069-2079.
-
(2013)
Critical Care Medicine
, vol.41
, pp. 2069-2079
-
-
Vincent, J.L.1
Ramesh, M.K.2
Ernest, D.3
LaRosa, S.P.4
Pachl, J.5
Aikawa, N.6
Hoste, E.7
Levy, H.8
Hirman, J.9
Levi, M.10
Daga, M.11
Kutsogiannis, D.J.12
Crowther, M.13
Bernard, G.R.14
Devriendt, J.15
Puigserver, J.V.16
Blanzaco, D.U.17
Esmon, C.T.18
Parrillo, J.E.19
Guzzi, L.20
Henderson, S.J.21
Pothirat, C.22
Mehta, P.23
Fareed, J.24
Talwar, D.25
Tsuruta, K.26
Gorelick, K.J.27
Osawa, Y.28
Kaul, I.29
more..
-
50
-
-
84937719061
-
Inflammation. Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis
-
Warnatsch, A., Ioannou, M., Wang, Q. & Papayannopoulos, V. (2015) Inflammation. Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis. Science, 349, 316-320.
-
(2015)
Science
, vol.349
, pp. 316-320
-
-
Warnatsch, A.1
Ioannou, M.2
Wang, Q.3
Papayannopoulos, V.4
-
51
-
-
84897881175
-
Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis
-
Wildhagen, K.C., Garcia de Frutos, P., Reutelingsperger, C.P., Schrijver, R., Areste, C., Ortega-Gomez, A., Deckers, N.M., Hemker, H.C., Soehnlein, O. & Nicolaes, G.A. (2014) Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis. Blood, 123, 1098-1101.
-
(2014)
Blood
, vol.123
, pp. 1098-1101
-
-
Wildhagen, K.C.1
Garcia de Frutos, P.2
Reutelingsperger, C.P.3
Schrijver, R.4
Areste, C.5
Ortega-Gomez, A.6
Deckers, N.M.7
Hemker, H.C.8
Soehnlein, O.9
Nicolaes, G.A.10
-
52
-
-
70449107044
-
Extracellular histones are major mediators of death in sepsis
-
Xu, J., Zhang, X., Pelayo, R., Monestier, M., Ammollo, C.T., Semeraro, F., Taylor, F.B., Esmon, N.L., Lupu, F. & Esmon, C.T. (2009) Extracellular histones are major mediators of death in sepsis. Nature Medicine, 15, 1318-1321.
-
(2009)
Nature Medicine
, vol.15
, pp. 1318-1321
-
-
Xu, J.1
Zhang, X.2
Pelayo, R.3
Monestier, M.4
Ammollo, C.T.5
Semeraro, F.6
Taylor, F.B.7
Esmon, N.L.8
Lupu, F.9
Esmon, C.T.10
-
53
-
-
80051882006
-
Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury
-
Xu, J., Zhang, X., Monestier, M., Esmon, N.L. & Esmon, C.T. (2011) Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury. Journal of Immunology, 187, 2626-2631.
-
(2011)
Journal of Immunology
, vol.187
, pp. 2626-2631
-
-
Xu, J.1
Zhang, X.2
Monestier, M.3
Esmon, N.L.4
Esmon, C.T.5
-
54
-
-
79958218315
-
Extracellular histone induces plasma hyaluronan-binding protein (factor VII activating protease) activation in vivo
-
Yamamichi, S., Fujiwara, Y., Kikuchi, T., Nishitani, M., Matsushita, Y. & Hasumi, K. (2011) Extracellular histone induces plasma hyaluronan-binding protein (factor VII activating protease) activation in vivo. Biochemical and Biophysical Research Communications, 409, 483-488.
-
(2011)
Biochemical and Biophysical Research Communications
, vol.409
, pp. 483-488
-
-
Yamamichi, S.1
Fujiwara, Y.2
Kikuchi, T.3
Nishitani, M.4
Matsushita, Y.5
Hasumi, K.6
-
55
-
-
84969778560
-
Extracellular histones induce tissue factor expression in vascular endothelial cells via TLR and activation of NF-kappaB and AP-1
-
Yang, X., Li, L., Liu, J., Lv, B. & Chen, F. (2015) Extracellular histones induce tissue factor expression in vascular endothelial cells via TLR and activation of NF-kappaB and AP-1. Thrombosis Research, 000, 000-000.
-
(2015)
Thrombosis Research
-
-
Yang, X.1
Li, L.2
Liu, J.3
Lv, B.4
Chen, F.5
-
56
-
-
84942865527
-
FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow
-
Zhu, S., Travers, R.J., Morrissey, J.H. & Diamond, S.L. (2015) FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow. Blood, 126, 1494-1502.
-
(2015)
Blood
, vol.126
, pp. 1494-1502
-
-
Zhu, S.1
Travers, R.J.2
Morrissey, J.H.3
Diamond, S.L.4
|