Role of extracellular histones in the cardiomyopathy of sepsis

FASEB Journal

Volumn 29, Issue 5, 2015, Pages 2185-2193

  Kalbitz, Miriam ^a,b   Grailer, Jamison J ^a   Fattahi, Fatemeh ^a   Jajou, Lawrence ^a   Herron, Todd J ^c   Campbell, Katherine F ^c   Zetoune, Firas S ^a   Bosmann, Markus ^d   Sarma, J Vidya ^a   Huber Lang, Markus ^b   Gebhard, Florian ^b   Loaiza, Randall ^c   Valdivia, Hector H ^c   Jalife, José ^c   Russell, Mark W ^a   Ward, Peter A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY HOSPITAL ULM   (Germany)

^c UNIVERSITY OF MICHIGAN   (United States)

^d UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Cardiomyocytes; Complement; Echocardiogram Doppler; NLRP3 inflammasome; Polymicrobial sepsis

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; COMPLEMENT COMPONENT C5A RECEPTOR; HISTONE; REACTIVE OXYGEN METABOLITE; CALCIUM; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; INTERLEUKIN 1BETA CONVERTING ENZYME; TLR2 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CARDIOMYOPATHY; CARDIOVASCULAR PERFORMANCE; CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS; CELL ISOLATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOPPLER ECHOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SPACE; FLOW CYTOMETRY; HEART DISEASE; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART OUTPUT; HEART PERFUSION; HEART RATE; HEART STROKE VOLUME; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN FUNCTION; RAT; TRANSTHORACIC ECHOCARDIOGRAPHY; YOUNG ADULT; ANIMAL; BLOOD; C57BL MOUSE; CARDIOMYOPATHIES; CELL CULTURE; COMPLICATION; DISEASE MODEL; METABOLISM; MITOCHONDRION; PATHOLOGY; PHYSIOLOGY; SEPSIS; SPRAGUE DAWLEY RAT;

MUS; RATTUS;

ANIMALS; CALCIUM; CARDIOMYOPATHIES; CARRIER PROTEINS; CASPASE 1; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HISTONES; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTOR, ANAPHYLATOXIN C5A; SEPSIS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 84934933688     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-268730     Document Type: Article

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