Letters

JAMA - Journal of the American Medical Association

Volumn 315, Issue 8, 2016, Pages 817-819

  Alhamdi, Yasir ^a   Abrams, Simon T ^a   Lane, Steven ^a   Wang, Guozheng ^a   Toh, Cheng Hock ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; BIOLOGICAL MARKER;

ADULT; AGED; APACHE; AREA UNDER THE CURVE; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DISEASE DURATION; DISEASE SEVERITY; FEMALE; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PREDICTION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTOPENIA; UNIVERSITY HOSPITAL; BLOOD; CHI SQUARE DISTRIBUTION; CRITICAL ILLNESS; MIDDLE AGED; NONPARAMETRIC TEST;

AGED; BIOMARKERS; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CRITICAL ILLNESS; FEMALE; HISTONES; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PLATELET COUNT; ROC CURVE; STATISTICS, NONPARAMETRIC; THROMBOCYTOPENIA;

EID: 84959264967     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2016.0136     Document Type: Article

References (6)

1. Fuchs TA, Bhandari AA, Wagner DD. Histones induce rapid and profound thrombocytopenia inmice. Blood. 2011;118(13):3708-3714.
2. Abrams ST, Zhang N, Dart C, et al. Human CRP defends against the toxicity of circulating histones. J Immunol. 2013;191(5):2495-2502.
3. Alhamdi Y, Abrams ST, Cheng Z, et al. Circulating histones are major mediators of cardiac injury in patients with sepsis. Crit Care Med. 2015;43(10):2094-2103.
4. Abrams ST, Zhang N, Manson J, et al. Circulating histones are mediators of trauma-associated lung injury. Am J Respir Crit Care Med. 2013;187(2):160-169.
5. De Labriolle A, Bonello L, Lemesle G, et al. Decline in platelet count in patients treated by percutaneous coronary intervention: definition, incidence, prognostic importance, and predictive factors. Eur Heart J. 2010;31(9):1079-1087.
6. Xu J, Zhang X, Pelayo R, et al. Extracellular histones are major mediators of death in sepsis. Nat Med. 2009;15(11):1318-1321.