Looking into laminin receptor: Critical discussion regarding the non-integrin 37/67-kDa laminin receptor/RPSA protein

Biological Reviews

Volumn 91, Issue 2, 2016, Pages 288-310

  Digiacomo, Vincent ^a   Meruelo, Daniel ^a,b,c  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c NEW YORK UNIVERSITY   (United States)

Author keywords

37 67 kDa laminin receptor; 37LBP; 37LRP; 67LR; P40; RPSA; YIGSR

Indexed keywords

LAMININ; LAMININ RECEPTOR; RIBOSOME PROTEIN; RPSA PROTEIN, HUMAN;

GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY;

GENE EXPRESSION REGULATION; HUMANS; LAMININ; RECEPTORS, LAMININ; RIBOSOMAL PROTEINS;

EID: 84962155132     PISSN: 14647931     EISSN: 1469185X     Source Type: Journal    
DOI: 10.1111/brv.12170     Document Type: Article

References (253)

1. Abe, K., Murakami, S., Mukae, N., Mita, T., Hashimoto, Y., Isemura, M., Shimo-Oka, T., Ii, I., Kimata, K., Narumi, K., Satoh, K. & Nukiwa, T. (1996). Presence of atypical laminin on the surface of mouse Lewis lung carcinoma cells. Tohoku Journal of Experimental Medicine 180, 33-44.
2. Abouseada, N. M., Assafi, M. S., Mahdavi, J., Oldfield, N. J., Wheldon, L. M., Wooldridge, K. G. & Ala'Aldeen, D. A. (2012). Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2. PLoS One 7, e46233.
3. Akache, B., Grimm, D., Pandey, K., Yant, S. R., Xu, H. & Kay, M. A. (2006). The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9. Journal of Virology 80, 9831-9836.
4. Amano, T., Fu, L., Marshak, A., Kwak, O. & Shi, Y. B. (2005a). Spatio-temporal regulation and cleavage by matrix metalloproteinase stromelysin-3 implicate a role for laminin receptor in intestinal remodeling during Xenopus laevis metamorphosis. Developmental Dynamics 234, 190-200.
5. Amano, T., Kwak, O., Fu, L., Marshak, A. & Shi, Y. B. (2005b). The matrix metalloproteinase stromelysin-3 cleaves laminin receptor at two distinct sites between the transmembrane domain and laminin binding sequence within the extracellular domain. Cell Research 15, 150-159.
6. Ando, K., Miyazaki, Y., Sawayama, Y., Tominaga, S., Matsuo, E., Yamasaki, R., Inoue, Y., Iwanaga, M., Imanishi, D., Tsushima, H., Fukushima, T., Imaizumi, Y., Taguchi, J., Yoshida, S., Hata, T. & Tomonaga, M. (2011). High expression of 67-kDa laminin receptor relates to the proliferation of leukemia cells and increases expression of GM-CSF receptor. Experimental Hematology 39, 179-186.e4.
7. Anger, A. M., Armache, J. P., Berninghausen, O., Habeck, M., Subklewe, M., Wilson, D. N. & Beckmann, R. (2013). Structures of the human and Drosophila 80S ribosome. Nature 497, 80-85.
8. Anilkumar, N. & Sudhakaran, P. R. (1993). Isolation and characterization of laminin binding protein from regenerating rat liver plasma membrane. Biochemistry and Molecular Biology International 31, 201-209.
9. Annabi, B., Currie, J. C., Moghrabi, A. & Beliveau, R. (2007). Inhibition of HuR and MMP-9 expression in macrophage-differentiated HL-60 myeloid leukemia cells by green tea polyphenol EGCg. Leukemia Research 31, 1277-1284.
10. Ardini, E., Pesole, G., Tagliabue, E., Magnifico, A., Castronovo, V., Sobel, M. E., Colnaghi, M. I. & Menard, S. (1998). The 67-kDa laminin receptor originated from a ribosomal protein that acquired a dual function during evolution. Molecular Biology and Evolution 15, 1017-1025.
11. Ardini, E., Sporchia, B., Pollegioni, L., Modugno, M., Ghirelli, C., Castiglioni, F., Tagliabue, E. & Menard, S. (2002). Identification of a novel function for 67-kDa laminin receptor: increase in laminin degradation rate and release of motility fragments. Cancer Research 62, 1321-1325.
12. Ardini, E., Tagliabue, E., Magnifico, A., Buto, S., Castronovo, V., Colnaghi, M. I. & Menard, S. (1997). Co-regulation and physical association of the 67-kDa monomeric laminin receptor and the alpha6beta4 integrin. Journal of Biological Chemistry 272, 2342-2345.
13. Armache, J. P., Anger, A. M., Marquez, V., Franckenberg, S., Frohlich, T., Villa, E., Berninghausen, O., Thomm, M., Arnold, G. J., Beckmann, R. & Wilson, D. N. (2013). Promiscuous behaviour of archaeal ribosomal proteins: implications for eukaryotic ribosome evolution. Nucleic Acids Research 41, 1284-1293.
14. Armache, J. P., Jarasch, A., Anger, A. M., Villa, E., Becker, T., Bhushan, S., Jossinet, F., Habeck, M., Dindar, G., Franckenberg, S., Marquez, V., Mielke, T., Thomm, M., Berninghausen, O., Beatrix, B., Soding, J., Westhof, E., Wilson, D. N. & Beckmann, R. (2010). Localization of eukaryote-specific ribosomal proteins in a 5.5-A cryo-EM map of the 80S eukaryotic ribosome. Proceedings of the National Academy of Sciences of the United States of America 107, 19754-19759.
15. Asano, Y., Takashima, S., Asakura, M., Shintani, Y., Liao, Y., Minamino, T., Asanuma, H., Sanada, S., Kim, J., Ogai, A., Fukushima, T., Oikawa, Y., Okazaki, Y., Kaneda, Y., Sato, M., Miyazaki, J., Kitamura, S., Tomoike, H., Kitakaze, M. & Hori, M. (2004). Lamr1 functional retroposon causes right ventricular dysplasia in mice. Nature Genetics 36, 123-130.
16. Aumailley, M. (2013). The laminin family. Cell Adhesion & Migration 7, 48-55.
17. Aumailley, M., Bruckner-Tuderman, L., Carter, W. G., Deutzmann, R., Edgar, D., Ekblom, P., Engel, J., Engvall, E., Hohenester, E., Jones, J. C., Kleinman, H. K., Marinkovich, M. P., Martin, G. R., Mayer, U., Meneguzzi, G., Miner, J. H., Miyazaki, K., Patarroyo, M., Paulsson, M., Quaranta, V., Sanes, J. R., Sasaki, T., Sekiguchi, K., Sorokin, L. M., Talts, J. F., Tryggvason, K., Uitto, J., Virtanen, I., von der Mark, K., Wewer, U. M., Yamada, Y. & Yurchenco, P. D. (2005). A simplified laminin nomenclature. Matrix Biology 24, 326-332.
18. Auth, D. & Brawerman, G. (1992). A 33-kDa polypeptide with homology to the laminin receptor: component of translation machinery. Proceedings of the National Academy of Sciences of the United States of America 89, 4368-4372.
19. Badger, J., Sauder, J. M., Adams, J. M., Antonysamy, S., Bain, K., Bergseid, M. G., Buchanan, S. G., Buchanan, M. D., Batiyenko, Y., Christopher, J. A., Emtage, S., Eroshkina, A., Feil, I., Furlong, E. B., Gajiwala, K. S., Gao, X., He, D., Hendle, J., Huber, A., Hoda, K., Kearins, P., Kissinger, C., Laubert, B., Lewis, H. A., Lin, J., Loomis, K., Lorimer, D., Louie, G., Maletic, M., Marsh, C. D., Miller, I., Molinari, J., Muller-Dieckmann, H. J., Newman, J. M., Noland, B. W., Pagarigan, B., Park, F., Peat, T. S., Post, K. W., Radojicic, S., Ramos, A., Romero, R., Rutter, M. E., Sanderson, W. E., Schwinn, K. D., Tresser, J., Winhoven, J., Wright, T. A., Wu, L., Xu, J. & Harris, T. J. (2005). Structural analysis of a set of proteins resulting from a bacterial genomics project. Proteins 60, 787-796.
20. Balasubramanian, S., Zheng, D., Liu, Y. J., Fang, G., Frankish, A., Carriero, N., Robilotto, R., Cayting, P. & Gerstein, M. (2009). Comparative analysis of processed ribosomal protein pseudogenes in four mammalian genomes. Genome Biology 10, R2.
21. Baloui, H., Stettler, O., Weiss, S., Nothias, F. & von Boxberg, Y. (2009). Upregulation in rat spinal cord microglia of the nonintegrin laminin receptor 37 kDa-LRP following activation by a traumatic lesion or peripheral injury. Journal of Neurotrauma 26, 195-207.
22. Bao, Z. Z., Muschler, J. & Horwitz, A. F. (1992). LBL, a novel, developmentally regulated, laminin-binding lectin. Journal of Biological Chemistry 267, 4974-4980.
23. Barsoum, A. L., Liu, B., Rohrer, J. W., Coggin, J. H. Jr., Tucker, J. A., Pannell, L. K. & Schwarzenberger, P. O. (2009). Production, safety and antitumor efficacy of recombinant Oncofetal Antigen/immature laminin receptor protein. Biomaterials 30, 3091-3099.
24. Basson, C. T., Knowles, W. J., Bell, L., Albelda, S. M., Castronovo, V., Liotta, L. A. & Madri, J. A. (1990). Spatiotemporal segregation of endothelial cell integrin and nonintegrin extracellular matrix-binding proteins during adhesion events. Journal of Cell Biology 110, 789-801.
25. Ben-Shem, A., Garreau de Loubresse, N., Melnikov, S., Jenner, L., Yusupova, G. & Yusupov, M. (2011). The structure of the eukaryotic ribosome at 3.0 A resolution. Science 334, 1524-1529.
26. Bernard, A., Gao-Li, J., Franco, C. A., Bouceba, T., Huet, A. & Li, Z. (2009). Laminin receptor involvement in the anti-angiogenic activity of pigment epithelium-derived factor. Journal of Biological Chemistry 284, 10480-10490.
27. Berno, V., Porrini, D., Castiglioni, F., Campiglio, M., Casalini, P., Pupa, S. M., Balsari, A., Menard, S. & Tagliabue, E. (2005). The 67 kDa laminin receptor increases tumor aggressiveness by remodeling laminin-1. Endocrine Related Cancer 12, 393-406.
28. Biragyn, A., Schiavo, R., Olkhanud, P., Sumitomo, K., King, A., McCain, M., Indig, F. E., Almanzar, G. & Baatar, D. (2007). Tumor-associated embryonic antigen-expressing vaccines that target CCR6 elicit potent CD8+ T cell-mediated protective and therapeutic antitumor immunity. Journal of Immunology 179, 1381-1388.
29. Blomster, H. A., Hietakangas, V., Wu, J., Kouvonen, P., Hautaniemi, S. & Sistonen, L. (2009). Novel proteomics strategy brings insight into the prevalence of SUMO-2 target sites. Molecular and Cellular Proteomics 8, 1382-1390.
30. Bogachek, M. V., Protopopova, E. V., Loktev, V. B., Zaitsev, B. N., Favre, M., Sekatskii, S. K. & Dietler, G. (2008). Immunochemical and single molecule force spectroscopy studies of specific interaction between the laminin binding protein and the West Nile virus surface glycoprotein E domain II. Journal of Molecular Recognition 21, 55-62.
31. Bolze, A., Mahlaoui, N., Byun, M., Turner, B., Trede, N., Ellis, S. R., Abhyankar, A., Itan, Y., Patin, E., Brebner, S., Sackstein, P., Puel, A., Picard, C., Abel, L., Quintana-Murci, L., Faust, S. N., Williams, A. P., Baretto, R., Duddridge, M., Kini, U., Pollard, A. J., Gaud, C., Frange, P., Orbach, D., Emile, J. F., Stephan, J. L., Sorensen, R., Plebani, A., Hammarstrom, L., Conley, M. E., Selleri, L. & Casanova, J. L. (2013). Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia. Science 340, 976-978.
32. Brodersen, D. E., Clemons, W. M. Jr., Carter, A. P., Wimberly, B. T. & Ramakrishnan, V. (2002). Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 S RNA. Journal of Molecular Biology 316, 725-768.
33. Brown, S. S., Malinoff, H. L. & Wicha, M. S. (1983). Connectin: cell surface protein that binds both laminin and actin. Proceedings of the National Academy of Sciences of the United States of America 80, 5927-5930.
34. Bryant, G., Haberern, C., Rao, C. N. & Liotta, L. A. (1986). Butyrate induced reduction of tumor cell laminin receptors. Cancer Research 46, 807-811.
35. Bushkin-Harav, I., Garty, N. B. & Littauer, U. Z. (1995). Down-regulation of a 67-kDa YIGSR-binding protein upon differentiation of human neuroblastoma cells. Journal of Biological Chemistry 270, 13422-13428.
36. Buto, S., Ghirelli, C., Aiello, P., Tagliabue, E., Ardini, E., Magnifico, A., Montuori, N., Sobel, M. E., Colnaghi, M. I. & Menard, S. (1997). Production and characterization of monoclonal antibodies directed against the laminin receptor precursor. International Journal of Biological Markers 12, 1-5.
37. Buto, S., Tagliabue, E., Ardini, E., Magnifico, A., Ghirelli, C., van den Brule, F., Castronovo, V., Colnaghi, M. I., Sobel, M. E. & Menard, S. (1998). Formation of the 67-kDa laminin receptor by acylation of the precursor. Journal of Cellular Biochemistry 69, 244-251.
38. Carbone, A., Gloghini, A., Colombatti, A., Castronovo, V. & Menard, S. (1995). Expression of the monomeric 67-kd laminin-binding protein in human lymphomas as defined by MLuC5 monoclonal antibody and paraffin section immunohistochemistry. Human Pathology 26, 541-546.
39. Castronovo, V., Claysmith, A. P., Barker, K. T., Cioce, V., Krutzsch, H. C. & Sobel, M. E. (1991a). Biosynthesis of the 67 kDa high affinity laminin receptor. Biochemical and Biophysical Research Communications 177, 177-183.
40. Castronovo, V., Taraboletti, G. & Sobel, M. E. (1991b). Functional domains of the 67-kDa laminin receptor precursor. Journal of Biological Chemistry 266, 20440-20446.
41. Castronovo, V., Luyten, F., van den Brule, F. & Sobel, M. E. (1992). Identification of a 14-kDa laminin binding protein (HLBP14) in human melanoma cells that is identical to the 14-kDa galactoside binding lectin. Archives of Biochemistry and Biophysics 297, 132-138.
42. Castronovo, V., Taraboletti, G., Liotta, L. A. & Sobel, M. E. (1989). Modulation of laminin receptor expression by estrogen and progestins in human breast cancer cell lines. Journal of the National Cancer Institute 81, 781-788.
43. Chen, J., Carcamo, J. M., Borquez-Ojeda, O., Erdjument-Bromage, H., Tempst, P. & Golde, D. W. (2003). The laminin receptor modulates granulocyte-macrophage colony-stimulating factor receptor complex formation and modulates its signaling. Proceedings of the National Academy of Sciences of the United States of America 100, 14000-14005.
44. Chen, A., Ganor, Y., Rahimipour, S., Ben-Aroya, N., Koch, Y. & Levite, M. (2002). The neuropeptides GnRH-II and GnRH-I are produced by human T cells and trigger laminin receptor gene expression, adhesion, chemotaxis and homing to specific organs. Nature Medicine 8, 1421-1426.
45. Chen, D., Milacic, V., Chen, M. S., Wan, S. B., Lam, W. H., Huo, C., Landis-Piwowar, K. R., Cui, Q. C., Wali, A., Chan, T. H. & Dou, Q. P. (2008). Tea polyphenols, their biological effects and potential molecular targets. Histology and Histopathology 23, 487-496.
46. Chen, F. X., Qian, Y. R., Duan, Y. H., Ren, W. W., Yang, Y., Zhang, C. C., Qiu, Y. M. & Ji, Y. H. (2009). Down-regulation of 67LR reduces the migratory activity of human glioma cells in vitro. Brain Research Bulletin 79, 402-408.
47. Chow, H. H., Cai, Y., Hakim, I. A., Crowell, J. A., Shahi, F., Brooks, C. A., Dorr, R. T., Hara, Y. & Alberts, D. S. (2003). Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals. Clinical Cancer Research 9, 3312-3319.
48. Chung, J. W., Hong, S. J., Kim, K. J., Goti, D., Stins, M. F., Shin, S., Dawson, V. L., Dawson, T. M. & Kim, K. S. (2003). 37-kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake. Journal of Biological Chemistry 278, 16857-16862.
49. Cioce, V., Margulies, I. M., Sobel, M. E. & Castronovo, V. (1993). Interaction between the 67 kilodalton metastasis-associated laminin receptor and laminin. Kidney International 43, 30-37.
50. Clausse, N., van den Brule, F., Delvenne, P., Jacobs, N., Franzen-Detrooz, E., Jackers, P. & Castronovo, V. (1998). TNF-alpha and IFN-gamma down-regulate the expression of the metastasis-associated bi-functional 37LRP/p40 gene and protein in transformed keratinocytes. Biochemical and Biophysical Research Communications 251, 564-569.
51. Clausse, N., Jackers, P., Jares, P., Joris, B., Sobel, M. E. & Castronovo, V. (1996). Identification of the active gene coding for the metastasis-associated 37LRP/p40 multifunctional protein. DNA and Cell Biology 15, 1009-1023.
52. Clement, B., Segui-Real, B., Savagner, P., Kleinman, H. K. & Yamada, Y. (1990). Hepatocyte attachment to laminin is mediated through multiple receptors. Journal of Cell Biology 110, 185-192.
53. Colnaghi, M. I. (1994). The simultaneous expression of c-erbB-2 oncoprotein and laminin receptor on primary breast tumors has a predicting potential analogous to that of the lymph node status. Advances in Experimental Medicine and Biology 353, 149-154.
54. Da Costa Dias, B., Jovanovic, K., Gonsalves, D., Moodley, K., Reusch, U., Knackmuss, S., Penny, C., Weinberg, M. S., Little, M. & Weiss, S. F. (2013). Anti-LRP/LR specific antibody IgG1-iS18 and knock-down of LRP/LR by shRNAs rescue cells from Abeta42 induced cytotoxicity. Science Reports 3-2702, 1-8.
55. Da Costa Dias, B., Jovanovic, K., Gonsalves, D. & Weiss, S. F. (2011). Structural and mechanistic commonalities of amyloid-beta and the prion protein. Prion 5, 126-137.
56. Davis, C. M., Papadopoulos, V., Jia, M. C., Yamada, Y., Kleinman, H. K. & Dym, M. (1991). Identification and partial characterization of laminin binding proteins in immature rat Sertoli cells. Experimental Cell Research 193, 262-273.
57. Demianova, M., Formosa, T. G. & Ellis, S. R. (1996). Yeast proteins related to the p40/laminin receptor precursor are essential components of the 40 S ribosomal subunit. Journal of Biological Chemistry 271, 11383-11391.
58. Di Giovanni, C., Grottesi, A. & Lavecchia, A. (2012). Conformational switch of a flexible loop in human laminin receptor determines laminin-1 interaction. European Biophysics Journal 41, 353-358.
59. Douville, P. J., Harvey, W. J. & Carbonetto, S. (1988). Isolation and partial characterization of high affinity laminin receptors in neural cells. Journal of Biological Chemistry 263, 14964-14969.
60. Engvall, E. & Wewer, U. M. (1996). Domains of laminin. Journal of Cellular Biochemistry 61, 493-501.
61. Fatehullah, A., Doherty, C., Pivato, G., Allen, G., Devine, L., Nelson, J. & Timson, D. J. (2010). Interactions of the 67 kDa laminin receptor and its precursor with laminin. Bioscience Reports 30, 73-79.
62. Ford, C. L., Randal-Whitis, L. & Ellis, S. R. (1999). Yeast proteins related to the p40/laminin receptor precursor are required for 20S ribosomal RNA processing and the maturation of 40S ribosomal subunits. Cancer Research 59, 704-710.
63. Formisano, P., Ragno, P., Pesapane, A., Alfano, D., Alberobello, A. T., Rea, V. E., Giusto, R., Rossi, F. W., Beguinot, F., Rossi, G. & Montuori, N. (2012). PED/PEA-15 interacts with the 67 kD laminin receptor and regulates cell adhesion, migration, proliferation and apoptosis. Journal of Cellular and Molecular Medicine 16, 1435-1446.
64. Friedrichs, B., Siegel, S., Kloess, M., Barsoum, A., Coggin, J. Jr., Rohrer, J., Jakob, I., Tiemann, M., Heidorn, K., Schulte, C., Kabelitz, D., Steinmann, J., Schmitz, N. & Zeis, M. (2008). Humoral immune responses against the immature laminin receptor protein show prognostic significance in patients with chronic lymphocytic leukemia. Journal of Immunology 180, 6374-6384.
65. Fromm-Dornieden, C., von der Heyde, S., Lytovchenko, O., Salinas-Riester, G., Brenig, B., Beissbarth, T. & Baumgartner, B. G. (2012). Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3 T3-L1 cells. BMC Molecular Biology 13-9, 1-12.
66. Fujimura, Y., Yamada, K. & Tachibana, H. (2005). A lipid raft-associated 67 kDa laminin receptor mediates suppressive effect of epigallocatechin-3-O-gallate on FcepsilonRI expression. Biochemical and Biophysical Research Communications 336, 674-681.
67. Fulcher, K. D., Welch, J. E., Davis, C. M., O'Brien, D. A. & Eddy, E. M. (1993). Characterization of laminin receptor messenger ribonucleic acid and protein expression in mouse spermatogenic cells. Biology of Reproduction 48, 674-682.
68. Furtado, G. C., Slowik, M., Kleinman, H. K. & Joiner, K. A. (1992). Laminin enhances binding of Toxoplasma gondii tachyzoites to J774 murine macrophage cells. Infection and Immunity 60, 2337-2342.
69. Garcia-Hernandez, M., Davies, E., Baskin, T. I. & Staswick, P. E. (1996). Association of plant p40 protein with ribosomes is enhanced when polyribosomes form during periods of active tissue growth. Plant Physiology 111, 559-568.
70. Gauczynski, S., Nikles, D., El-Gogo, S., Papy-Garcia, D., Rey, C., Alban, S., Barritault, D., Lasmezas, C. I. & Weiss, S. (2006). The 37-kDa/67-kDa laminin receptor acts as a receptor for infectious prions and is inhibited by polysulfated glycanes. Journal of Infectious Diseases 194, 702-709.
71. Gauczynski, S., Peyrin, J. M., Haik, S., Leucht, C., Hundt, C., Rieger, R., Krasemann, S., Deslys, J. P., Dormont, D., Lasmezas, C. I. & Weiss, S. (2001). The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein. EMBO Journal 20, 5863-5875.
72. Givant-Horwitz, V., Davidson, B. & Reich, R. (2004). Laminin-induced signaling in tumor cells: the role of the M(r) 67, 000 laminin receptor. Cancer Research 64, 3572-3579.
73. Golebiowski, F., Matic, I., Tatham, M. H., Cole, C., Yin, Y., Nakamura, A., Cox, J., Barton, G. J., Mann, M. & Hay, R. T. (2009). System-wide changes to SUMO modifications in response to heat shock. Science Signaling 2, ra24.
74. Graf, J., Iwamoto, Y., Sasaki, M., Martin, G. R., Kleinman, H. K., Robey, F. A. & Yamada, Y. (1987a). Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding. Cell 48, 989-996.
75. Graf, J., Ogle, R. C., Robey, F. A., Sasaki, M., Martin, G. R., Yamada, Y. & Kleinman, H. K. (1987b). A pentapeptide from the laminin B1 chain mediates cell adhesion and binds the 67, 000 laminin receptor. Biochemistry 26, 6896-6900.
76. Grosso, L. E., Park, P. W. & Mecham, R. P. (1991). Characterization of a putative clone for the 67-kilodalton elastin/laminin receptor suggests that it encodes a cytoplasmic protein rather than a cell surface receptor. Biochemistry 30, 3346-3350.
77. Gu, X. & Masters, K. S. (2010). Regulation of valvular interstitial cell calcification by adhesive peptide sequences. Journal of Biomedical Materials Research, Part A 93, 1620-1630.
78. Guerra-Rebollo, M., Mateo, F., Franke, K., Huen, M. S., Lopitz-Otsoa, F., Rodriguez, M. S., Plans, V. & Thomson, T. M. (2012). Nucleolar exit of RNF8 and BRCA1 in response to DNA damage. Experimental Cell Research 318, 2365-2376.
79. Guirguis, R., Margulies, I., Taraboletti, G., Schiffmann, E. & Liotta, L. (1987). Cytokine-induced pseudopodial protrusion is coupled to tumour cell migration. Nature 329, 261-263.
80. Guo, D., Han, J., Adam, B. L., Colburn, N. H., Wang, M. H., Dong, Z., Eizirik, D. L., She, J. X. & Wang, C. Y. (2005). Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. Biochemical and Biophysical Research Communications 337, 1308-1318.
81. Guo, N. H., Krutzsch, H. C., Vogel, T. & Roberts, D. D. (1992). Interactions of a laminin-binding peptide from a 33-kDa protein related to the 67-kDa laminin receptor with laminin and melanoma cells are heparin-dependent. Journal of Biological Chemistry 267, 17743-17747.
82. Hadley, M. A., Weeks, B. S., Kleinman, H. K. & Dym, M. (1990). Laminin promotes formation of cord-like structures by Sertoli cells in vitro. Developmental Biology 140, 318-327.
83. Han, J., Logsdon, P. M. & Ellis, S. R. (2008). LAMR1 (+/-) mice as a model for Diamond-Blackfan anemia. Mouse Genome Informatics (MGI) direct data submission. The Jackson Laboratory. MGI Ref ID J:138267.
84. Hara, K., Satoh, K. & Ide, H. (1997). Apical ectodermal ridge-dependent expression of the chick 67 kDa laminin binding protein gene (cLbp) in developing limb bud. Zoological Science 14, 969-978.
85. Hendrix, M. J., Wood, W. R., Seftor, E. A., Lotan, D., Nakajima, M., Misiorowski, R. L., Seftor, R. E., Stetler-Stevenson, W. G., Bevacqua, S. J., Liotta, L. A., Sobel, M. E., Raz, A. & Lotan, R. (1990). Retinoic acid inhibition of human melanoma cell invasion through a reconstituted basement membrane and its relation to decreases in the expression of proteolytic enzymes and motility factor receptor. Cancer Research 50, 4121-4130.
86. Hong, Y. C., Lee, W. M., Kong, H. H., Jeong, H. J. & Chung, D. I. (2004). Molecular cloning and characterization of a cDNA encoding a laminin-binding protein (AhLBP) from Acanthamoeba healyi. Experimental Parasitology 106, 95-102.
87. Huang, S. H. & Jong, A. (2009). Evolving role of laminin receptors in microbial pathogenesis and therapeutics of CNS infection. Future Microbiology 4, 959-962.
88. Huang, J., Yan, J., Zhang, J., Zhu, S., Wang, Y., Shi, T., Zhu, C., Chen, C., Liu, X., Cheng, J., Mustelin, T., Feng, G. S., Chen, G. & Yu, J. (2012). SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane. Nature Communications 3-911, 1-12.
89. Huard, T. K., Malinoff, H. L. & Wicha, M. S. (1986). Macrophages express a plasma membrane receptor for basement membrane laminin. American Journal of Pathology 123, 365-370.
90. Hundt, C., Peyrin, J. M., Haik, S., Gauczynski, S., Leucht, C., Rieger, R., Riley, M. L., Deslys, J. P., Dormont, D., Lasmezas, C. I. & Weiss, S. (2001). Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor. EMBO Journal 20, 5876-5886.
91. Iwamoto, Y., Robey, F. A., Graf, J., Sasaki, M., Kleinman, H. K., Yamada, Y. & Martin, G. R. (1987). YIGSR, a synthetic laminin pentapeptide, inhibits experimental metastasis formation. Science 238, 1132-1134.
92. Jackers, P., Clausse, N., Fernandez, M., Berti, A., Princen, F., Wewer, U., Sobel, M. E. & Castronovo, V. (1996a). Seventeen copies of the human 37 kDa laminin receptor precursor/p40 ribosome-associated protein gene are processed pseudogenes arisen from retropositional events. Biochimica et Biophysica Acta 1305, 98-104.
93. Jackers, P., Minoletti, F., Belotti, D., Clausse, N., Sozzi, G., Sobel, M. E. & Castronovo, V. (1996b). Isolation from a multigene family of the active human gene of the metastasis-associated multifunctional protein 37LRP/p40 at chromosome 3p21.3. Oncogene 13, 495-503.
94. Jamieson, K. V., Hubbard, S. R. & Meruelo, D. (2011). Structure-guided identification of a laminin binding site on the laminin receptor precursor. Journal of Molecular Biology 405, 24-32.
95. Jamieson, K. V., Wu, J., Hubbard, S. R. & Meruelo, D. (2008). Crystal structure of the human laminin receptor precursor. Journal of Biological Chemistry 283, 3002-3005.
96. Jaseja, M., Mergen, L., Gillette, K., Forbes, K., Sehgal, I. & Copie, V. (2005). Structure-function studies of the functional and binding epitope of the human 37 kDa laminin receptor precursor protein. Journal of Peptide Research 66, 9-18.
97. Jovanovic, K., Gonsalves, D., Da Costa Dias, B., Moodley, K., Reusch, U., Knackmuss, S., Penny, C., Weinberg, M. S., Little, M. & Weiss, S. F. (2013). Anti-LRP/LR specific antibodies and shRNAs impede amyloid beta shedding in Alzheimer's disease. Scientific Reports 3, 2699.
98. Jovanovic, K., Loos, B., Da Costa Dias, B., Penny, C. & Weiss, S. F. (2014). High resolution imaging study of interactions between the 37 kDa/67 kDa laminin receptor and APP, beta-secretase and gamma-secretase in Alzheimer's disease. PLoS One 9(6)-e100373, 1-10.
99. Karpatova, M., Tagliabue, E., Castronovo, V., Magnifico, A., Ardini, E., Morelli, D., Belotti, D., Colnaghi, M. I. & Menard, S. (1996). Shedding of the 67-kD laminin receptor by human cancer cells. Journal of Cellular Biochemistry 60, 226-234.
100. Katagiri, Y. U., Kiyokawa, N., Nakamura, K., Takenouchi, H., Taguchi, T., Okita, H., Umezawa, A. & Fujimoto, J. (2005). Laminin binding protein, 34/67 laminin receptor, carries stage-specific embryonic antigen-4 epitope defined by monoclonal antibody Raft.2. Biochemical and Biophysical Research Communications 332, 1004-1011.
101. Kazmin, D. A., Hoyt, T. R., Taubner, L., Teintze, M. & Starkey, J. R. (2000). Phage display mapping for peptide 11 sensitive sequences binding to laminin-1. Journal of Molecular Biology 298, 431-445.
102. Keppel, E. & Schaller, H. C. (1991). A 33 kDa protein with sequence homology to the 'laminin binding protein' is associated with the cytoskeleton in hydra and in mammalian cells. Journal of Cell Science 100 (Pt. 4), 789-797.
103. Ketchart, W., Smith, K. M., Krupka, T., Wittmann, B. M., Hu, Y., Rayman, P. A., Doughman, Y. Q., Albert, J. M., Bai, X., Finke, J. H., Xu, Y., Exner, A. A. & Montano, M. M. (2013). Inhibition of metastasis by HEXIM1 through effects on cell invasion and angiogenesis. Oncogene 32, 3829-3839.
104. Khalfaoui, T., Groulx, J. F., Sabra, G., Guezguez, A., Basora, N., Vermette, P. & Beaulieu, J. F. (2013). Laminin receptor 37/67LR regulates adhesion and proliferation of normal human intestinal epithelial cells. PLoS One 8, e74337.
105. Kielian, M., Chanel-Vos, C. & Liao, M. (2010). Alphavirus entry and membrane fusion. Viruses 2, 796-825.
106. Kikkawa, Y., Hozumi, K., Katagiri, F., Nomizu, M., Kleinman, H. K. & Koblinski, J. E. (2013). Laminin-111-derived peptides and cancer. Cell Adhesion & Migration 7, 150-256.
107. Kim, D. G., Choi, J. W., Lee, J. Y., Kim, H., Oh, Y. S., Lee, J. W., Tak, Y. K., Song, J. M., Razin, E., Yun, S. H. & Kim, S. (2012). Interaction of two translational components, lysyl-tRNA synthetase and p40/37LRP, in plasma membrane promotes laminin-dependent cell migration. FASEB Journal 26, 4142-4159.
108. Kim, D. G., Lee, J. Y., Kwon, N. H., Fang, P., Zhang, Q., Wang, J., Young, N. L., Guo, M., Cho, H. Y., Mushtaq, A. U., Jeon, Y. H., Choi, J. W., Han, J. M., Kang, H. W., Joo, J. E., Hur, Y., Kang, W., Yang, H., Nam, D. H., Lee, M. S., Lee, J. W., Kim, E. S., Moon, A., Kim, K., Kim, D., Kang, E. J., Moon, Y., Rhee, K. H., Han, B. W., Yang, J. S., Han, G., Yang, W. S., Lee, C., Wang, M. W. & Kim, S. (2014). Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction. Nature Chemical Biology 10, 29-34.
109. Kim, K., Li, L., Kozlowski, K., Suh, H. S., Cao, W. & Ballermann, B. J. (2005a). The protein phosphatase-1 targeting subunit TIMAP regulates LAMR1 phosphorylation. Biochemical and Biophysical Research Communications 338, 1327-1334.
110. Kim, K. J., Chung, J. W. & Kim, K. S. (2005b). 67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells. Journal of Biological Chemistry 280, 1360-1368.
111. Kinoshita, K., Kaneda, Y., Sato, M., Saeki, Y., Wataya-Kaneda, M. & Hoffmann, A. (1998). LBP-p40 binds DNA tightly through associations with histones H2A, H2B, and H4. Biochemical and Biophysical Research Communications 253, 277-282.
112. Kiss, A. M., Jady, B. E., Bertrand, E. & Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Molecular and Cellular Biology 24, 5797-5807.
113. Kleinman, H. K., Ogle, R. C., Cannon, F. B., Little, C. D., Sweeney, T. M. & Luckenbill-Edds, L. (1988). Laminin receptors for neurite formation. Proceedings of the National Academy of Sciences of the United States of America 85, 1282-1286.
114. Ku, H. C., Chang, H. H., Liu, H. C., Hsiao, C. H., Lee, M. J., Hu, Y. J., Hung, P. F., Liu, C. W. & Kao, Y. H. (2009). Green tea (-)-epigallocatechin gallate inhibits insulin stimulation of 3 T3-L1 preadipocyte mitogenesis via the 67-kDa laminin receptor pathway. American Journal of Physiology. Cell Physiology 297, C121-C132.
115. Ku, H. C., Liu, H. S., Hung, P. F., Chen, C. L., Liu, H. C., Chang, H. H., Tsuei, Y. W., Shih, L. J., Lin, C. L., Lin, C. M. & Kao, Y. H. (2012). Green tea (-)-epigallocatechin gallate inhibits IGF-I and IGF-II stimulation of 3 T3-L1 preadipocyte mitogenesis via the 67-kDa laminin receptor, but not AMP-activated protein kinase pathway. Molecular Nutrition & Food Research 56, 580-592.
116. Landowski, T. H., Dratz, E. A. & Starkey, J. R. (1995a). Studies of the structure of the metastasis-associated 67 kDa laminin binding protein: fatty acid acylation and evidence supporting dimerization of the 32 kDa gene product to form the mature protein. Biochemistry 34, 11276-11287.
117. Landowski, T. H., Uthayakumar, S. & Starkey, J. R. (1995b). Control pathways of the 67 kDa laminin binding protein: surface expression and activity of a new ligand binding domain. Clinical and Experimental Metastasis 13, 357-372.
118. Languino, L. R., Gehlsen, K. R., Wayner, E., Carter, W. G., Engvall, E. & Ruoslahti, E. (1989). Endothelial cells use alpha 2 beta 1 integrin as a laminin receptor. Journal of Cell Biology 109, 2455-2462.
119. Laurie, G. W., Horikoshi, S., Killen, P. D., Segui-Real, B. & Yamada, Y. (1989). In situ hybridization reveals temporal and spatial changes in cellular expression of mRNA for a laminin receptor, laminin, and basement membrane (type IV) collagen in the developing kidney. Journal of Cell Biology 109, 1351-1362.
120. Laurie, G. W., Stone, C. M. & Yamada, Y. (1991). Elevated 32-kDa LBP and low laminin mRNA expression in developing mouse cerebrum. Differentiation 46, 173-179.
121. Lesot, H., Kuhl, U. & Mark, K. (1983). Isolation of a laminin-binding protein from muscle cell membranes. EMBO Journal 2, 861-865.
122. Lestrade, L. & Weber, M. J. (2006). snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. Nucleic Acids Research 34, D158-D162.
123. Leucht, C., Simoneau, S., Rey, C., Vana, K., Rieger, R., Lasmezas, C. I. & Weiss, S. (2003). The 37 kDa/67 kDa laminin receptor is required for PrP(Sc) propagation in scrapie-infected neuronal cells. EMBO Reports 4, 290-295.
124. Liotta, L. A., Horan Hand, P., Rao, C. N., Bryant, G., Barsky, S. H. & Schlom, J. (1985). Monoclonal antibodies to the human laminin receptor recognize structurally distinct sites. Experimental Cell Research 156, 117-126.
125. Lomize, M. A., Pogozheva, I. D., Joo, H., Mosberg, H. I. & Lomize, A. L. (2012). OPM database and PPM web server: resources for positioning of proteins in membranes. Nucleic Acids Research 40 (Database Issue), D370-D376.
126. Lopez-Ribot, J. L., Casanova, M., Monteagudo, C., Sepulveda, P. & Martinez, J. P. (1994). Evidence for the presence of a high-affinity laminin receptor-like molecule on the surface of Candida albicans yeast cells. Infection and Immunity 62, 742-746.
127. Ludwig, G. V., Kondig, J. P. & Smith, J. F. (1996). A putative receptor for Venezuelan equine encephalitis virus from mosquito cells. Journal of Virology 70, 5592-5599.
128. Maeda, T., Titani, K. & Sekiguchi, K. (1994). Cell-adhesive activity and receptor-binding specificity of the laminin-derived YIGSR sequence grafted onto Staphylococcal protein A. Journal of Biochemistry 115, 182-189.
129. Mak, J. C. (2012). Potential role of green tea catechins in various disease therapies: progress and promise. Clinical and Experimental Pharmacology and Physiology 39, 265-273.
130. Makrides, S., Chitpatima, S. T., Bandyopadhyay, R. & Brawerman, G. (1988). Nucleotide sequence for a major messenger RNA for a 40 kilodalton polypeptide that is under translational control in mouse tumor cells. Nucleic Acids Research 16, 2349.
131. Malinoff, H. L. & Wicha, M. S. (1983). Isolation of a cell surface receptor protein for laminin from murine fibrosarcoma cells. Journal of Cell Biology 96, 1475-1479.
132. Malygin, A. A., Babaylova, E. S., Loktev, V. B. & Karpova, G. G. (2011). A region in the C-terminal domain of ribosomal protein SA required for binding of SA to the human 40S ribosomal subunit. Biochimie 93, 612-617.
133. Manza, L. L., Codreanu, S. G., Stamer, S. L., Smith, D. L., Wells, K. S., Roberts, R. L. & Liebler, D. C. (2004). Global shifts in protein sumoylation in response to electrophile and oxidative stress. Chemical Research in Toxicology 17, 1706-1715.
134. von der Mark, K. & Risse, G. (1987). Isolation and characterization of laminin receptors. Methods in Enzymology 144, 490-507.
135. Martignone, S., Menard, S., Bufalino, R., Cascinelli, N., Pellegrini, R., Tagliabue, E., Andreola, S., Rilke, F. & Colnaghi, M. I. (1993). Prognostic significance of the 67-kilodalton laminin receptor expression in human breast carcinomas. Journal of the National Cancer Institute 85, 398-402.
136. Martin, S., Nishimune, A., Mellor, J. R. & Henley, J. M. (2007). SUMOylation regulates kainate-receptor-mediated synaptic transmission. Nature 447, 321-325.
137. Masuda, T., Sakuma, C., Kobayashi, K., Kikuchi, K., Soda, E., Shiga, T. & Yaginuma, H. (2009). Laminin peptide YIGSR and its receptor regulate sensory axonal response to the chemoattractive guidance cue in the chick embryo. Journal of Neuroscience Research 87, 353-359.
138. McCaffery, P., Neve, R. L. & Drager, U. C. (1990). A dorso-ventral asymmetry in the embryonic retina defined by protein conformation. Proceedings of the National Academy of Sciences of the United States of America 87, 8570-8574.
139. McKenna, D. J., Simpson, D. A., Feeney, S., Gardiner, T. A., Boyle, C., Nelson, J. & Stitt, A. W. (2001). Expression of the 67 kDa laminin receptor (67LR) during retinal development: correlations with angiogenesis. Experimental Eye Research 73, 81-92.
140. Mecham, R. P., Hinek, A., Griffin, G. L., Senior, R. M. & Liotta, L. A. (1989). The elastin receptor shows structural and functional similarities to the 67-kDa tumor cell laminin receptor. Journal of Biological Chemistry 264, 16652-16657.
141. Melnick, M. B., Noll, E. & Perrimon, N. (1993). The Drosophila stubarista phenotype is associated with a dosage effect of the putative ribosome-associated protein D-p40 on spineless. Genetics 135, 553-564.
142. Menard, S., Castronovo, V., Tagliabue, E. & Sobel, M. E. (1997). New insights into the metastasis-associated 67 kD laminin receptor. Journal of Cellular Biochemistry 67, 155-165.
143. Menard, S., Tagliabue, E. & Colnaghi, M. I. (1998). The 67 kDa laminin receptor as a prognostic factor in human cancer. Breast Cancer Research and Treatment 52, 137-145.
144. Mercurio, A. M. & Shaw, L. M. (1988). Macrophage interactions with laminin: PMA selectively induces the adherence and spreading of mouse macrophages on a laminin substratum. Journal of Cell Biology 107, 1873-1880.
145. Mercurio, A. M. & Shaw, L. M. (1991). Laminin binding proteins. Bioessays 13, 469-473.
146. Messeguer, X., Escudero, R., Farre, D., Nunez, O., Martinez, J. & Alba, M. M. (2002). PROMO: detection of known transcription regulatory elements using species-tailored searches. Bioinformatics 18, 333-334.
147. Miner, J. H. (2008). Laminins and their roles in mammals. Microscopy Research and Technique 71, 349-356.
148. Modugno, M., Tagliabue, E., Ardini, E., Berno, V., Galmozzi, E., De Bortoli, M., Castronovo, V. & Menard, S. (2002). p53-dependent downregulation of metastasis-associated laminin receptor. Oncogene 21, 7478-7487.
149. Montuori, N., Selleri, C., Risitano, A. M., Raiola, A. M., Ragno, P., Del Vecchio, L., Rotoli, B. & Rossi, G. (1999). Expression of the 67-kDa laminin receptor in acute myeloid leukemia cells mediates adhesion to laminin and is frequently associated with monocytic differentiation. Clinical Cancer Research 5, 1465-1472.
150. Montuori, N., Siri, J., Simmons, T., Gillet, C., Senterre, G., Wrathall, L. & Sobel, M. E. (1995). Precursor-product relationship between a 37-kDa polypeptide and the 67-kDa laminin receptor. The FASEB Journal 9(3), A539 . Inaccessible meeting abstract (SICI: 0892-6638(1995)9:3 < 539:PRBA3P > 2.0.ZU;2-8).
151. Montuori, N. & Sobel, M. E. (1996). The 67-kDa laminin receptor and tumor progression. Current Topics in Microbiology and Immunology 213 (Pt. 1), 205-214.
152. Moodley, K. & Weiss, S. F. (2013). Downregulation of the non-integrin laminin receptor reduces cellular viability by inducing apoptosis in lung and cervical cancer cells. PLoS One 8, e57409.
153. Moss, B. L., Taubner, L., Sample, Y. K., Kazmin, D. A., Copie, V. & Starkey, J. R. (2006). Tumor shedding of laminin binding protein modulates angiostatin production in vitro and interferes with plasmin-derived inhibition of angiogenesis in aortic ring cultures. International Journal of Cancer 118, 2421-2432.
154. Nakai, M., Mundy, G. R., Williams, P. J., Boyce, B. & Yoneda, T. (1992). A synthetic antagonist to laminin inhibits the formation of osteolytic metastases by human melanoma cells in nude mice. Cancer Research 52, 5395-5399.
155. Narasimhan, S., Armstrong, M. Y., Rhee, K., Edman, J. C., Richards, F. F. & Spicer, E. (1994). Gene for an extracellular matrix receptor protein from Pneumocystis carinii. Proceedings of the National Academy of Sciences of the United States of America 91, 7440-7444.
156. Narumi, K., Inoue, A., Tanaka, M., Isemura, M., Shimo-Oka, T., Abe, T., Nukiwa, T. & Satoh, K. (1999). Inhibition of experimental metastasis of human fibrosarcoma cells by anti-recombinant 37-kDa laminin binding protein antibody. Japanese Journal of Cancer Research 90, 425-431.
157. Nelson, J., McFerran, N. V., Pivato, G., Chambers, E., Doherty, C., Steele, D. & Timson, D. J. (2008). The 67 kDa laminin receptor: structure, function and role in disease. Bioscience Reports 28, 33-48.
158. Ochieng, J., Warfield, P., Green-Jarvis, B. & Fentie, I. (1999). Galectin-3 regulates the adhesive interaction between breast carcinoma cells and elastin. Journal of Cellular Biochemistry 75, 505-514.
159. O'Donohue, M. F., Choesmel, V., Faubladier, M., Fichant, G. & Gleizes, P. E. (2010). Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits. Journal of Cell Biology 190, 853-866.
160. Omar, A., Jovanovic, K., Da Costa Dias, B., Gonsalves, D., Moodley, K., Caveney, R., Mbazima, V. & Weiss, S. F. (2011). Patented biological approaches for the therapeutic modulation of the 37 kDa/67 kDa laminin receptor. Expert Opinion on Therapeutic Patents 21, 35-53.
161. Omar, A., Reusch, U., Knackmuss, S., Little, M. & Weiss, S. F. (2012). Anti-LRP/LR-specific antibody IgG1-iS18 significantly reduces adhesion and invasion of metastatic lung, cervix, colon and prostate cancer cells. Journal of Molecular Biology 419, 102-109.
162. Orihuela, C. J., Mahdavi, J., Thornton, J., Mann, B., Wooldridge, K. G., Abouseada, N., Oldfield, N. J., Self, T., Ala'Aldeen, D. A. & Tuomanen, E. I. (2009). Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models. Journal of Clinical Investigation 119, 1638-1646.
163. Ould-Abeih, M. B., Petit-Topin, I., Zidane, N., Baron, B. & Bedouelle, H. (2012). Multiple folding states and disorder of ribosomal protein SA, a membrane receptor for laminin, anticarcinogens, and pathogens. Biochemistry 51, 4807-4821.
164. Pampeno, C., Derkatch, I. L. & Meruelo, D. (2014). Interaction of human laminin receptor with Sup35, the [PSI+] prion-forming protein from S. cerevisiae: a yeast model for studies of LamR interactions with amyloidogenic proteins. PLoS One 9(1), e86013.
165. Park, E., Choi, Y., Ahn, E., Park, I. & Yun, Y. (2009). The adaptor protein LAD/TSAd mediates laminin-dependent T cell migration via association with the 67 kDa laminin binding protein. Experimental and Molecular Medicine 41, 728-736.
166. Pellegrini, R., Martignone, S., Menard, S. & Colnaghi, M. I. (1994). Laminin receptor expression and function in small-cell lung carcinoma. International Journal of Cancer. Supplement 8, 116-120.
167. Poon, S. L., Klausen, C., Hammond, G. L. & Leung, P. C. (2011). 37-kDa laminin receptor precursor mediates GnRH-II-induced MMP-2 expression and invasiveness in ovarian cancer cells. Molecular Endocrinology 25, 327-338.
168. Rabacchi, S. A., Neve, R. L. & Drager, U. C. (1990). A positional marker for the dorsal embryonic retina is homologous to the high-affinity laminin receptor. Development 109, 521-531.
169. Rabl, J., Leibundgut, M., Ataide, S. F., Haag, A. & Ban, N. (2011). Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1. Science 331, 730-736.
170. Raghunath, P. N., Sidhu, G. S., Coon, H. C., Liu, K., Srikantan, V. & Maheshwari, R. K. (1993). Interferons upregulate the expression of laminin and its receptor LBP-32 in cultured cells. Journal of Biological Regulators and Homeostatic Agents 7, 22-30.
171. Rao, N. C., Barsky, S. H., Terranova, V. P. & Liotta, L. A. (1983). Isolation of a tumor cell laminin receptor. Biochemical and Biophysical Research Communications 111, 804-808.
172. Rao, C. N., Castronovo, V., Schmitt, M. C., Wewer, U. M., Claysmith, A. P., Liotta, L. A. & Sobel, M. E. (1989). Evidence for a precursor of the high-affinity metastasis-associated murine laminin receptor. Biochemistry 28, 7476-7486.
173. Rao, M., Manishen, W. J., Maheshwari, Y., Sykes, D. E., Siyanova, E. Y., Tyner, A. L. & Weiser, M. M. (1994). Laminin receptor expression in rat intestine and liver during development and differentiation. Gastroenterology 107, 764-772.
174. Rao, C. N., Margulies, I. M., Goldfarb, R. H., Madri, J. A., Woodley, D. T. & Liotta, L. A. (1982). Differential proteolytic susceptibility of laminin alpha and beta subunits. Archives of Biochemistry and Biophysics 219, 65-70.
175. Rea, V. E., Rossi, F. W., De Paulis, A., Ragno, P., Selleri, C. & Montuori, N. (2012). 67 kDa laminin receptor: structure, function and role in cancer and infection. Le Infezioni in Medicina 20(Suppl. 2), 8-12.
176. Ren, J., Gao, X., Jin, C., Zhu, M., Wang, X., Shaw, A., Wen, L., Yao, X. & Xue, Y. (2009). Systematic study of protein sumoylation: development of a site-specific predictor of SUMOsp 2.0. Proteomics 9, 3409-3412.
177. Rescan, P. Y., Clement, B., Yamada, Y., Segui-Real, B., Baffet, G., Guguen-Guillouzo, C. & Guillouzo, A. (1990). Differential expression of laminin chains and receptor (LBP-32) in fetal and neoplastic hepatocytes compared to normal adult hepatocytes in vivo and in culture. American Journal of Pathology 137, 701-709.
178. Rieger, R., Edenhofer, F., Lasmezas, C. I. & Weiss, S. (1997). The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells. Nature Medicine 3, 1383-1388.
179. Rieger, R., Lasmezas, C. I. & Weiss, S. (1999). Role of the 37 kDa laminin receptor precursor in the life cycle of prions. Transfusion Clinique et Biologique 6, 7-16.
180. Rohde, H., Bachinger, H. P. & Timpl, R. (1980). Characterization of pepsin fragments of laminin in a tumor basement membrane. Evidence for the existence of related proteins. Hoppe-Seylers Zeitschrift fur Physiologische Chemie 361, 1651-1660.
181. Romanov, V., Sobel, M. E., pinto da Silva, P., Menard, S. & Castronovo, V. (1994). Cell localization and redistribution of the 67 kD laminin receptor and alpha 6 beta 1 integrin subunits in response to laminin stimulation: an immunogold electron microscopy study. Cell Adhesion and Communication 2, 201-209.
182. Ross, S. A., Ahrens, R. A. & De Luca, L. M. (1994). Retinoic acid enhances adhesiveness, laminin and integrin beta 1 synthesis, and retinoic acid receptor expression in F9 teratocarcinoma cells. Journal of Cellular Physiology 159, 263-273.
183. Roy, A., Kucukural, A. & Zhang, Y. (2010). I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols 5, 725-738.
184. Ruff, E. A., Rimoldi, O. J., Raghu, B. & Eliceiri, G. L. (1993). Three small nucleolar RNAs of unique nucleotide sequences. Proceedings of the National Academy of Sciences of the United States of America 90, 635-638.
185. Rush, J., Moritz, A., Lee, K. A., Guo, A., Goss, V. L., Spek, E. J., Zhang, H., Zha, X. M., Polakiewicz, R. D. & Comb, M. J. (2005). Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Nature Biotechnology 23, 94-101.
186. Ryan, M. C., Christiano, A. M., Engvall, E., Wewer, U. M., Miner, J. H., Sanes, J. R. & Burgeson, R. E. (1996). The functions of laminins: lessons from in vivo studies. Matrix Biology 15, 369-381.
187. Sakaguchi, S., Ishibashi, D. & Matsuda, H. (2009). Antibody-based immunotherapeutic attempts in experimental animal models of prion diseases. Expert Opinion on Therapeutic Patents 19, 907-917.
188. Salama, R. H., Muramatsu, H., Zou, K., Inui, T., Kimura, T. & Muramatsu, T. (2001). Midkine binds to 37-kDa laminin binding protein precursor, leading to nuclear transport of the complex. Experimental Cell Research 270, 13-20.
189. Sanjuan, X., Fernandez, P. L., Miquel, R., Munoz, J., Castronovo, V., Menard, S., Palacin, A., Cardesa, A. & Campo, E. (1996). Overexpression of the 67-kD laminin receptor correlates with tumour progression in human colorectal carcinoma. Journal of Pathology 179, 376-380.
190. Sato, M., Kinoshita, K., Kaneda, Y., Saeki, Y., Iwamatsu, A. & Tanaka, K. (1996). Analysis of nuclear localization of laminin binding protein precursor p40 (LBP/p40). Biochemical and Biophysical Research Communications 229, 896-901.
191. Sato, M., Kong, C. J., Yoshida, H., Nakamura, T., Wada, A., Shimoda, C. & Kaneda, Y. (2003). Ribosomal proteins S0 and S21 are involved in the stability of 18S rRNA in fission yeast, Schizosaccharomyces pombe. Biochemical and Biophysical Research Communications 311, 942-947.
192. Sato, M., Saeki, Y., Tanaka, K. & Kaneda, Y. (1999). Ribosome-associated protein LBP/p40 binds to S21 protein of 40S ribosome: analysis using a yeast two-hybrid system. Biochemical and Biophysical Research Communications 256, 385-390.
193. Satoh, K., Narumi, K., Abe, T., Sakai, T., Kikuchi, T., Tanaka, M., Shimo-Oka, T., Uchida, M., Tezuka, F., Isemura, M. & Nukiwa, T. (1999). Diminution of 37-kDa laminin binding protein expression reduces tumour formation of murine lung cancer cells. British Journal of Cancer 80, 1115-1122.
194. Satoh, K., Narumi, K., Isemura, M., Sakai, T., Abe, T., Matsushima, K., Okuda, K. & Motomiya, M. (1992). Increased expression of the 67 kDa-laminin receptor gene in human small cell lung cancer. Biochemical and Biophysical Research Communications 182, 746-752.
195. Scheiman, J., Jamieson, K. V., Ziello, J., Tseng, J. C. & Meruelo, D. (2010a). Extraribosomal functions associated with the C terminus of the 37/67 kDa laminin receptor are required for maintaining cell viability. Cell Death & Disease 1, e42.
196. Scheiman, J., Tseng, J. C., Zheng, Y. & Meruelo, D. (2010b). Multiple functions of the 37/67-kd laminin receptor make it a suitable target for novel cancer gene therapy. Molecular Therapy 18, 63-74.
197. Schimmel, J., Larsen, K. M., Matic, I., van Hagen, M., Cox, J., Mann, M., Andersen, J. S. & Vertegaal, A. C. (2008). The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle. Molecular and Cellular Proteomics 7, 2107-2122.
198. Schlessinger, A., Punta, M., Yachdav, G., Kajan, L. & Rost, B. (2009). Improved disorder prediction by combination of orthogonal approaches. PLoS One 4, e4433.
199. Schuwirth, B. S., Borovinskaya, M. A., Hau, C. W., Zhang, W., Vila-Sanjurjo, A., Holton, J. M. & Cate, J. H. (2005). Structures of the bacterial ribosome at 3.5 A resolution. Science 310, 827-834.
200. Selleri, C., Ragno, P., Ricci, P., Visconte, V., Scarpato, N., Carriero, M. V., Rotoli, B., Rossi, G. & Montuori, N. (2006). The metastasis-associated 67-kDa laminin receptor is involved in G-CSF-induced hematopoietic stem cell mobilization. Blood 108, 2476-2484.
201. Sengupta, S., Shovlin, F. E., Slomiany, A. & Slomiany, B. L. (1991). Identification of laminin receptor in gingival tissue and its interaction with tooth cementum laminin. International Journal of Biochemistry 23, 115-121.
202. Sepulveda, P., Cervera, A. M., Lopez-Ribot, J. L., Chaffin, W. L., Martinez, J. P. & Gozalbo, D. (1996). Cloning and characterization of a cDNA coding for Candida albicans polyubiquitin. Journal of Medical & Veterinary Mycology 34, 315-322.
203. Shi, Y. E., Torri, J., Yieh, L., Sobel, M. E., Yamada, Y., Lippman, M. E., Dickson, R. B. & Thompson, E. W. (1993). Expression of 67 kDa laminin receptor in human breast cancer cells: regulation by progestins. Clinical and Experimental Metastasis 11, 251-261.
204. Shin, S. J., Lee, S. E., Boo, J. H., Kim, M., Yoon, Y. D., Kim, S. I. & Mook-Jung, I. (2004). Profiling proteins related to amyloid deposited brain of Tg2576 mice. Proteomics 4, 3359-3368.
205. Sigalov, A. B. (2011). Uncoupled binding and folding of immune signaling-related intrinsically disordered proteins. Progress in Biophysics and Molecular Biology 106, 525-536.
206. Simoneau, S., Haik, S., Leucht, C., Dormont, D., Deslys, J. P., Weiss, S. & Lasmezas, C. (2003). Different isoforms of the non-integrin laminin receptor are present in mouse brain and bind PrP. Biological Chemistry 384, 243-246.
207. Simons, K. & Ehehalt, R. (2002). Cholesterol, lipid rafts, and disease. Journal of Clinical Investigation 110, 597-603.
208. Soeda, S., Ishida, S., Honda, O., Shimeno, H. & Nagamatsu, A. (1994). Aminated fucoidan promotes the invasion of 3 LL cells through reconstituted basement membrane: its possible mechanism of action. Cancer Letters 85, 133-138.
209. Starkey, J. R., Uthayakumar, S. & Berglund, D. L. (1999). Cell surface and substrate distribution of the 67-kDa laminin-binding protein determined by using a ligand photoaffinity probe. Cytometry 35, 37-47.
210. Stitt, A. W., McKenna, D., Simpson, D. A., Gardiner, T. A., Harriott, P., Archer, D. B. & Nelson, J. (1998). The 67-kd laminin receptor is preferentially expressed by proliferating retinal vessels in a murine model of ischemic retinopathy. American Journal of Pathology 152, 1359-1365.
211. Strauss, J. H., Wang, K. S., Schmaljohn, A. L., Kuhn, R. J. & Strauss, E. G. (1994). Host-cell receptors for Sindbis virus. Archives of Virology. Supplementum 9, 473-484.
212. Susantad, T. & Smith, D. R. (2008). siRNA-mediated silencing of the 37/67-kDa high affinity laminin receptor in Hep3B cells induces apoptosis. Cellular & Molecular Biology Letters 13, 452-464.
213. Tabb-Massey, A., Caffrey, J. M., Logsden, P., Taylor, S., Trent, J. O. & Ellis, S. R. (2003). Ribosomal proteins Rps0 and Rps21 of Saccharomyces cerevisiae have overlapping functions in the maturation of the 3' end of 18S rRNA. Nucleic Acids Research 31, 6798-6805.
214. Tachibana, H., Koga, K., Fujimura, Y. & Yamada, K. (2004). A receptor for green tea polyphenol EGCG. Nature Structural & Molecular Biology 11, 380-381.
215. Tagliabue, E. & Pastorino, U. (1996). Re: killing of laminin receptor-positive human lung cancers by tumor-infiltrating lymphocytes bearing gamma delta + T-cell receptors. Journal of the National Cancer Institute 88, 1241-1242.
216. Tandon, N. N., Holland, E. A., Kralisz, U., Kleinman, H. K., Robey, F. A. & Jamieson, G. A. (1991). Interaction of human platelets with laminin and identification of the 67 kDa laminin receptor on platelets. Biochemical Journal 274 (Pt. 2), 535-542.
217. Taraboletti, G., Belotti, D., Giavazzi, R., Sobel, M. E. & Castronovo, V. (1993). Enhancement of metastatic potential of murine and human melanoma cells by laminin receptor peptide G: attachment of cancer cells to subendothelial matrix as a pathway for hematogenous metastasis. Journal of the National Cancer Institute 85, 235-240.
218. Terranova, V. P. & Lyall, R. M. (1986). Chemotaxis of human gingival epithelial cells to laminin. A mechanism for epithelial cell apical migration. Journal of Periodontology 57, 311-317.
219. Thepparit, C. & Smith, D. R. (2004). Serotype-specific entry of dengue virus into liver cells: identification of the 37-kilodalton/67-kilodalton high-affinity laminin receptor as a dengue virus serotype 1 receptor. Journal of Virology 78, 12647-12656.
220. Thongtan, T., Wikan, N., Wintachai, P., Rattanarungsan, C., Srisomsap, C., Cheepsunthorn, P. & Smith, D. R. (2012). Characterization of putative Japanese encephalitis virus receptor molecules on microglial cells. Journal of Medical Virology 84, 615-623.
221. Tohgo, A., Takasawa, S., Munakata, H., Yonekura, H., Hayashi, N. & Okamoto, H. (1994). Structural determination and characterization of a 40 kDa protein isolated from rat 40 S ribosomal subunit. FEBS Letters 340, 133-138.
222. Turpeenniemi-Hujanen, T., Thorgeirsson, U. P., Rao, C. N. & Liotta, L. A. (1986). Laminin increases the release of type IV collagenase from malignant cells. Journal of Biological Chemistry 261, 1883-1889.
223. Umeda, D., Tachibana, H. & Yamada, K. (2005). Epigallocatechin-3-O-gallate disrupts stress fibers and the contractile ring by reducing myosin regulatory light chain phosphorylation mediated through the target molecule 67 kDa laminin receptor. Biochemical and Biophysical Research Communications 333, 628-635.
224. Umeda, D., Yano, S., Yamada, K. & Tachibana, H. (2008a). Green tea polyphenol epigallocatechin-3-gallate signaling pathway through 67-kDa laminin receptor. Journal of Biological Chemistry 283, 3050-3058.
225. Umeda, D., Yano, S., Yamada, K. & Tachibana, H. (2008b). Involvement of 67-kDa laminin receptor-mediated myosin phosphatase activation in antiproliferative effect of epigallocatechin-3-O-gallate at a physiological concentration on Caco-2 colon cancer cells. Biochemical and Biophysical Research Communications 371, 172-176.
226. Uversky, V. N. (2013). The most important thing is the tail: multitudinous functionalities of intrinsically disordered protein termini. FEBS Letters 587, 1891-1901.
227. Valasek, L., Mathew, A. A., Shin, B. S., Nielsen, K. H., Szamecz, B. & Hinnebusch, A. G. (2003). The yeast eIF3 subunits TIF32/a, NIP1/c, and eIF5 make critical connections with the 40S ribosome in vivo. Genes and Development 17, 786-799.
228. Vana, K., Zuber, C., Pflanz, H., Kolodziejczak, D., Zemora, G., Bergmann, A. K. & Weiss, S. (2009). LRP/LR as an alternative promising target in therapy of prion diseases, Alzheimer's disease and cancer. Infectious Disorders Drug Targets 9, 69-80.
229. van der Veen, A. G. & Ploegh, H. L. (2012). Ubiquitin-like proteins. Annual Review of Biochemistry 81, 323-357.
230. Venticinque, L., Jamieson, K. V. & Meruelo, D. (2011). Interactions between laminin receptor and the cytoskeleton during translation and cell motility. PLoS One 6, e15895.
231. Venticinque, L. & Meruelo, D. (2012). Comprehensive proteomic analysis of nonintegrin laminin receptor interacting proteins. Journal of Proteome Research 11, 4863-4872.
232. Viacava, P., Naccarato, A. G., Collecchi, P., Menard, S., Castronovo, V. & Bevilacqua, G. (1997). The spectrum of 67-kD laminin receptor expression in breast carcinoma progression. Journal of Pathology 182, 36-44.
233. Wang, K. S., Kuhn, R. J., Strauss, E. G., Ou, S. & Strauss, J. H. (1992). High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells. Journal of Virology 66, 4992-5001.
234. Weeks, B. S., DiSalvo, J. & Kleinman, H. K. (1990). Laminin-mediated process formation in neuronal cells involves protein dephosphorylation. Journal of Neuroscience Research 27, 418-426.
235. Weeks, B. S., Kopp, J. B., Horikoshi, S., Cannon, F. B., Garrett, M., Kleinman, H. K. & Klotman, P. E. (1991). Adult and fetal human mesangial cells interact with specific laminin domains. American Journal of Physiology 261, F688-F695.
236. Weisser, M., Voigts-Hoffmann, F., Rabl, J., Leibundgut, M. & Ban, N. (2013). The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A. Nature Structural & Molecular Biology 20, 1015-1017.
237. Wenzel, S., Henning, K., Habbig, A., Forst, S., Schreckenberg, R., Heger, J., Maxeiner, H. & Schluter, K. D. (2010). TGF-beta1 improves cardiac performance via up-regulation of laminin receptor 37/67 in adult ventricular cardiomyocytes. Basic Research in Cardiology 105, 621-629.
238. Wewer, U. M., Liotta, L. A., Jaye, M., Ricca, G. A., Drohan, W. N., Claysmith, A. P., Rao, C. N., Wirth, P., Coligan, J. E., Albrechtsen, R., Mudryj, M. & Sobel, M. E. (1986). Altered levels of laminin receptor mRNA in various human carcinoma cells that have different abilities to bind laminin. Proceedings of the National Academy of Sciences of the United States of America 83, 7137-7141.
239. Wewer, U. M., Taraboletti, G., Sobel, M. E., Albrechtsen, R. & Liotta, L. A. (1987). Role of laminin receptor in tumor cell migration. Cancer Research 47, 5691-5698.
240. Wilkinson, K. A. & Henley, J. M. (2010). Mechanisms, regulation and consequences of protein SUMOylation. Biochemical Journal 428, 133-145.
241. Wimberly, B. T., Brodersen, D. E., Clemons, W. M. Jr., Morgan-Warren, R. J., Carter, A. P., Vonrhein, C., Hartsch, T. & Ramakrishnan, V. (2000). Structure of the 30S ribosomal subunit. Nature 407, 327-339.
242. Wohlschlegel, J. A., Johnson, E. S., Reed, S. I. & Yates, J. R. III (2004). Global analysis of protein sumoylation in Saccharomyces cerevisiae. Journal of Biological Chemistry 279, 45662-45668.
243. Xu, D. & Zhang, Y. (2012). Ab initio protein structure assembly using continuous structure fragments and optimized knowledge-based force field. Proteins 80, 1715-1735.
244. Yamada, K. M., Kennedy, D. W., Yamada, S. S., Gralnick, H., Chen, W. T. & Akiyama, S. K. (1990). Monoclonal antibody and synthetic peptide inhibitors of human tumor cell migration. Cancer Research 50, 4485-4496.
245. Yamamura, K., Kibbey, M. C., Jun, S. H. & Kleinman, H. K. (1993). Effect of Matrigel and laminin peptide YIGSR on tumor growth and metastasis. Seminars in Cancer Biology 4, 259-265.
246. Yannariello-Brown, J., Wewer, U., Liotta, L. & Madri, J. A. (1988). Distribution of a 69-kD laminin-binding protein in aortic and microvascular endothelial cells: modulation during cell attachment, spreading, and migration. Journal of Cell Biology 106, 1773-1786.
247. Yow, H. K., Wong, J. M., Chen, H. S., Lee, C. G., Davis, S., Steele, G. D. Jr. & Chen, L. B. (1988). Increased mRNA expression of a laminin-binding protein in human colon carcinoma: complete sequence of a full-length cDNA encoding the protein. Proceedings of the National Academy of Sciences of the United States of America 85, 6394-6398.
248. Yurchenco, P. D. (2011). Basement membranes: cell scaffoldings and signaling platforms. Cold Spring Harbor Perspectives in Biology 3(2)-a004911, 1-27.
249. Zhang, L., Leggatt, G. R., Kalinna, B. H., Piva, T. J. & McManus, D. P. (1997). Cloning and expression of a cDNA encoding a nonintegrin laminin-binding protein from Echinococcus granulosus with localization of the laminin-binding domain. Molecular and Biochemical Parasitology 87, 183-192.
250. Zhang, J., Liang, Y. & Zhang, Y. (2011). Atomic-level protein structure refinement using fragment-guided molecular dynamics conformation sampling. Structure 19, 1784-1795.
251. Zidane, N., Ould-Abeih, M. B., Petit-Topin, I. & Bedouelle, H. (2013). The folded and disordered domains of human ribosomal protein SA have both idiosyncratic and shared functions as membrane receptors. Bioscience Reports 33, 113-124.
252. Zuber, C., Knackmuss, S., Rey, C., Reusch, U., Rottgen, P., Frohlich, T., Arnold, G. J., Pace, C., Mitteregger, G., Kretzschmar, H. A., Little, M. & Weiss, S. (2008a). Single chain Fv antibodies directed against the 37 kDa/67 kDa laminin receptor as therapeutic tools in prion diseases. Molecular Immunology 45, 144-151.
253. Zuber, C., Mitteregger, G., Schuhmann, N., Rey, C., Knackmuss, S., Rupprecht, W., Reusch, U., Kretzschmar, H. A., Hallek, M., Buning, H. & Weiss, S. (2008b). Delivery of single-chain antibodies (scFvs) directed against the 37/67 kDa laminin receptor into mice via recombinant adeno-associated viral vectors for prion disease gene therapy. Journal of General Virology 89, 2055-2061.