-
1
-
-
78649336706
-
The DNA damage response: making it safe to play with knives
-
Ciccia A., Elledge S.J. The DNA damage response: making it safe to play with knives. Mol. Cell 2010, 40:179-204.
-
(2010)
Mol. Cell
, vol.40
, pp. 179-204
-
-
Ciccia, A.1
Elledge, S.J.2
-
2
-
-
36749022214
-
The DNA damage response: ten years after
-
Harper J.W., Elledge S.J. The DNA damage response: ten years after. Mol. Cell 2007, 28:739-745.
-
(2007)
Mol. Cell
, vol.28
, pp. 739-745
-
-
Harper, J.W.1
Elledge, S.J.2
-
3
-
-
79952235291
-
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
-
Polo S.E., Jackson S.P. Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev. 2011, 25:409-433.
-
(2011)
Genes Dev.
, vol.25
, pp. 409-433
-
-
Polo, S.E.1
Jackson, S.P.2
-
5
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
Huen M.S., Grant R., Manke I., Minn K., Yu X., Yaffe M.B., Chen J. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 2007, 131:901-914.
-
(2007)
Cell
, vol.131
, pp. 901-914
-
-
Huen, M.S.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
Yaffe, M.B.6
Chen, J.7
-
6
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
Kolas N.K., Chapman J.R., Nakada S., Ylanko J., Chahwan R., Sweeney F.D., Panier S., Mendez M., Wildenhain J., Thomson T.M., Pelletier L., Jackson S.P., Durocher D. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science 2007, 318:1637-1640.
-
(2007)
Science
, vol.318
, pp. 1637-1640
-
-
Kolas, N.K.1
Chapman, J.R.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
Sweeney, F.D.6
Panier, S.7
Mendez, M.8
Wildenhain, J.9
Thomson, T.M.10
Pelletier, L.11
Jackson, S.P.12
Durocher, D.13
-
7
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand N., Bekker-Jensen S., Faustrup H., Melander F., Bartek J., Lukas C., Lukas J. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 2007, 131:887-900.
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
Lukas, J.7
-
8
-
-
36749025467
-
S.J. Rnf8 ubiquitin/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage
-
B. Wang, S.J. Rnf8 ubiquitin/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage, Proc. Nat. Acad. Sci. U. S. A. 104 (2007) 20759-20763.
-
(2007)
Proc. Nat. Acad. Sci. U. S. A.
, vol.104
, pp. 20759-20763
-
-
Wang, B.1
-
9
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil C., Mailand N., Bekker-Jensen S., Menard P., Larsen D.H., Pepperkok R., Ellenberg J., Panier S., Durocher D., Bartek J., Lukas J., Lukas C. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 2009, 136:435-446.
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
Pepperkok, R.6
Ellenberg, J.7
Panier, S.8
Durocher, D.9
Bartek, J.10
Lukas, J.11
Lukas, C.12
-
10
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
Stewart G.S., Panier S., Townsend K., Al-Hakim A.K., Kolas N.K., Miller E.S., Nakada S., Ylanko J., Olivarius S., Mendez M., Oldreive C., Wildenhain J., Tagliaferro A., Pelletier L., Taubenheim N., Durandy A., Byrd P.J., Stankovic T., Taylor A.M., Durocher D. The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 2009, 136:420-434.
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
Miller, E.S.6
Nakada, S.7
Ylanko, J.8
Olivarius, S.9
Mendez, M.10
Oldreive, C.11
Wildenhain, J.12
Tagliaferro, A.13
Pelletier, L.14
Taubenheim, N.15
Durandy, A.16
Byrd, P.J.17
Stankovic, T.18
Taylor, A.M.19
Durocher, D.20
more..
-
11
-
-
77955867565
-
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1
-
Nakada S., Tai I., Panier S., Al-Hakim A., Iemura S., Juang Y.C., O'Donnell L., Kumakubo A., Munro M., Sicheri F., Gingras A.C., Natsume T., Suda T., Durocher D. Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature 2010, 466:941-946.
-
(2010)
Nature
, vol.466
, pp. 941-946
-
-
Nakada, S.1
Tai, I.2
Panier, S.3
Al-Hakim, A.4
Iemura, S.5
Juang, Y.C.6
O'Donnell, L.7
Kumakubo, A.8
Munro, M.9
Sicheri, F.10
Gingras, A.C.11
Natsume, T.12
Suda, T.13
Durocher, D.14
-
12
-
-
66849138419
-
Solving the RIDDLE of 53BP1 recruitment to sites of damage
-
Stewart G.S. Solving the RIDDLE of 53BP1 recruitment to sites of damage. Cell Cycle 2009, 8:1532-1538.
-
(2009)
Cell Cycle
, vol.8
, pp. 1532-1538
-
-
Stewart, G.S.1
-
13
-
-
36749029369
-
RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling
-
Stewart G.S., Stankovic T., Byrd P.J., Wechsler T., Miller E.S., Huissoon A., Drayson M.T., West S.C., Elledge S.J., Taylor A.M. RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling. Proc. Natl. Acad. Sci. U S A 2007, 104:16910-16915.
-
(2007)
Proc. Natl. Acad. Sci. U S A
, vol.104
, pp. 16910-16915
-
-
Stewart, G.S.1
Stankovic, T.2
Byrd, P.J.3
Wechsler, T.4
Miller, E.S.5
Huissoon, A.6
Drayson, M.T.7
West, S.C.8
Elledge, S.J.9
Taylor, A.M.10
-
14
-
-
76249097153
-
The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination
-
Ramachandran S., Chahwan R., Nepal R.M., Frieder D., Panier S., Roa S., Zaheen A., Durocher D., Scharff M.D., Martin A. The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination. Proc. Natl. Acad. Sci. U S A 2010, 107:809-814.
-
(2010)
Proc. Natl. Acad. Sci. U S A
, vol.107
, pp. 809-814
-
-
Ramachandran, S.1
Chahwan, R.2
Nepal, R.M.3
Frieder, D.4
Panier, S.5
Roa, S.6
Zaheen, A.7
Durocher, D.8
Scharff, M.D.9
Martin, A.10
-
15
-
-
77952318450
-
Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer
-
Li L., Halaby M.J., Hakem A., Cardoso R., El Ghamrasni S., Harding S., Chan N., Bristow R., Sanchez O., Durocher D., Hakem R. Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer. J. Exp. Med. 2010, 207:983-997.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 983-997
-
-
Li, L.1
Halaby, M.J.2
Hakem, A.3
Cardoso, R.4
El Ghamrasni, S.5
Harding, S.6
Chan, N.7
Bristow, R.8
Sanchez, O.9
Durocher, D.10
Hakem, R.11
-
16
-
-
33646117239
-
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
-
Bekker-Jensen S., Lukas C., Kitagawa R., Melander F., Kastan M.B., Bartek J., Lukas J. Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J. Cell Biol. 2006, 173:195-206.
-
(2006)
J. Cell Biol.
, vol.173
, pp. 195-206
-
-
Bekker-Jensen, S.1
Lukas, C.2
Kitagawa, R.3
Melander, F.4
Kastan, M.B.5
Bartek, J.6
Lukas, J.7
-
17
-
-
75949124023
-
Assembly of checkpoint and repair machineries at DNA damage sites
-
Huen M.S., Chen J. Assembly of checkpoint and repair machineries at DNA damage sites. Trends Biochem. Sci. 2009, 35:101-108.
-
(2009)
Trends Biochem. Sci.
, vol.35
, pp. 101-108
-
-
Huen, M.S.1
Chen, J.2
-
18
-
-
78649336111
-
The nucleolus under stress
-
Boulon S., Westman B.J., Hutten S., Boisvert F.M., Lamond A.I. The nucleolus under stress. Mol. Cell 2010, 40:216-227.
-
(2010)
Mol. Cell
, vol.40
, pp. 216-227
-
-
Boulon, S.1
Westman, B.J.2
Hutten, S.3
Boisvert, F.M.4
Lamond, A.I.5
-
19
-
-
39849092543
-
Regulation of mitotic exit by the RNF8 ubiquitin ligase
-
Plans V., Guerra-Rebollo M., Thomson T.M. Regulation of mitotic exit by the RNF8 ubiquitin ligase. Oncogene 2008, 27:1355-1365.
-
(2008)
Oncogene
, vol.27
, pp. 1355-1365
-
-
Plans, V.1
Guerra-Rebollo, M.2
Thomson, T.M.3
-
20
-
-
33144459648
-
The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation
-
Plans V., Scheper J., Soler M., Loukili N., Okano Y., Thomson T.M. The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation. J. Cell. Biochem. 2006, 97:572-582.
-
(2006)
J. Cell. Biochem.
, vol.97
, pp. 572-582
-
-
Plans, V.1
Scheper, J.2
Soler, M.3
Loukili, N.4
Okano, Y.5
Thomson, T.M.6
-
21
-
-
0037039159
-
Directed proteomic analysis of the human nucleolus
-
Andersen J.S., Lyon C.E., Fox A.H., Leung A.K., Lam Y.W., Steen H., Mann M., Lamond A.I. Directed proteomic analysis of the human nucleolus. Curr. Biol. 2002, 12:1-11.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1-11
-
-
Andersen, J.S.1
Lyon, C.E.2
Fox, A.H.3
Leung, A.K.4
Lam, Y.W.5
Steen, H.6
Mann, M.7
Lamond, A.I.8
-
22
-
-
58149197604
-
NOPdb: nucleolar proteome database-2008 update
-
Ahmad Y., Boisvert F.M., Gregor P., Cobley A., Lamond A.I. NOPdb: nucleolar proteome database-2008 update. Nucleic Acids Res. 2009, 37:D181-184.
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Ahmad, Y.1
Boisvert, F.M.2
Gregor, P.3
Cobley, A.4
Lamond, A.I.5
-
23
-
-
70449084692
-
Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities
-
Hjerpe R., Aillet F., Lopitz-Otsoa F., Lang V., England P., Rodriguez M.S. Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities. EMBO Rep. 2009, 10:1250-1258.
-
(2009)
EMBO Rep.
, vol.10
, pp. 1250-1258
-
-
Hjerpe, R.1
Aillet, F.2
Lopitz-Otsoa, F.3
Lang, V.4
England, P.5
Rodriguez, M.S.6
-
24
-
-
11244269445
-
The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
-
Aylon Y., Liefshitz B., Kupiec M. The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle. EMBO J. 2004, 23:4868-4875.
-
(2004)
EMBO J.
, vol.23
, pp. 4868-4875
-
-
Aylon, Y.1
Liefshitz, B.2
Kupiec, M.3
-
25
-
-
77449086623
-
DNA resection in eukaryotes: deciding how to fix the break
-
Huertas P. DNA resection in eukaryotes: deciding how to fix the break. Nat. Struct. Mol. Biol. 2010, 17:11-16.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 11-16
-
-
Huertas, P.1
-
26
-
-
7244220162
-
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
-
Ira G., Pellicioli A., Balijja A., Wang X., Fiorani S., Carotenuto W., Liberi G., Bressan D., Wan L., Hollingsworth N.M., Haber J.E., Foiani M. DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1. Nature 2004, 431:1011-1017.
-
(2004)
Nature
, vol.431
, pp. 1011-1017
-
-
Ira, G.1
Pellicioli, A.2
Balijja, A.3
Wang, X.4
Fiorani, S.5
Carotenuto, W.6
Liberi, G.7
Bressan, D.8
Wan, L.9
Hollingsworth, N.M.10
Haber, J.E.11
Foiani, M.12
-
27
-
-
11944274520
-
Nucleolar proteome dynamics
-
Andersen J.S., Lam Y.W., Leung A.K., Ong S.E., Lyon C.E., Lamond A.I., Mann M. Nucleolar proteome dynamics. Nature 2005, 433:77-83.
-
(2005)
Nature
, vol.433
, pp. 77-83
-
-
Andersen, J.S.1
Lam, Y.W.2
Leung, A.K.3
Ong, S.E.4
Lyon, C.E.5
Lamond, A.I.6
Mann, M.7
-
28
-
-
0031830066
-
Nucleolar localization of BRCA1 protein in human breast cancer
-
Tulchin N., Ornstein L., Bleiweiss I.J., Mendlowitz M., Weinstein E., Dikman S.H. Nucleolar localization of BRCA1 protein in human breast cancer. Int. J. Oncol. 1998, 13:513-518.
-
(1998)
Int. J. Oncol.
, vol.13
, pp. 513-518
-
-
Tulchin, N.1
Ornstein, L.2
Bleiweiss, I.J.3
Mendlowitz, M.4
Weinstein, E.5
Dikman, S.H.6
-
29
-
-
33845286542
-
BRCA1 foci in normal S-phase nuclei are linked to interphase centromeres and replication of pericentric heterochromatin
-
Pageau G.J., Lawrence J.B. BRCA1 foci in normal S-phase nuclei are linked to interphase centromeres and replication of pericentric heterochromatin. J. Cell Biol. 2006, 175:693-701.
-
(2006)
J. Cell Biol.
, vol.175
, pp. 693-701
-
-
Pageau, G.J.1
Lawrence, J.B.2
-
30
-
-
84861800872
-
Three-dimensional imaging reveals the spatial separation of gammaH2AX-MDC1-53BP1 and RNF8-RNF168-BRCA1-A complexes at ionizing radiation-induced foci
-
Mok M.T., Henderson B.R. Three-dimensional imaging reveals the spatial separation of gammaH2AX-MDC1-53BP1 and RNF8-RNF168-BRCA1-A complexes at ionizing radiation-induced foci. Radiother. Oncol. 2012, 103:415-420.
-
(2012)
Radiother. Oncol.
, vol.103
, pp. 415-420
-
-
Mok, M.T.1
Henderson, B.R.2
-
31
-
-
34249946686
-
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
-
Wang B., Matsuoka S., Ballif B.A., Zhang D., Smogorzewska A., Gygi S.P., Elledge S.J. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science 2007, 316:1194-1198.
-
(2007)
Science
, vol.316
, pp. 1194-1198
-
-
Wang, B.1
Matsuoka, S.2
Ballif, B.A.3
Zhang, D.4
Smogorzewska, A.5
Gygi, S.P.6
Elledge, S.J.7
-
32
-
-
78649375395
-
Translational regulation of gene expression during conditions of cell stress
-
Spriggs K.A., Bushell M., Willis A.E. Translational regulation of gene expression during conditions of cell stress. Mol. Cell 2010, 40:228-237.
-
(2010)
Mol. Cell
, vol.40
, pp. 228-237
-
-
Spriggs, K.A.1
Bushell, M.2
Willis, A.E.3
-
33
-
-
66149137639
-
Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes
-
Powley I.R., Kondrashov A., Young L.A., Dobbyn H.C., Hill K., Cannell I.G., Stoneley M., Kong Y.W., Cotes J.A., Smith G.C., Wek R., Hayes C., Gant T.W., Spriggs K.A., Bushell M., Willis A.E. Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes. Genes Dev. 2009, 23:1207-1220.
-
(2009)
Genes Dev.
, vol.23
, pp. 1207-1220
-
-
Powley, I.R.1
Kondrashov, A.2
Young, L.A.3
Dobbyn, H.C.4
Hill, K.5
Cannell, I.G.6
Stoneley, M.7
Kong, Y.W.8
Cotes, J.A.9
Smith, G.C.10
Wek, R.11
Hayes, C.12
Gant, T.W.13
Spriggs, K.A.14
Bushell, M.15
Willis, A.E.16
-
34
-
-
0026554288
-
A 33-kDa polypeptide with homology to the laminin receptor: component of translation machinery
-
Auth D., Brawerman G. A 33-kDa polypeptide with homology to the laminin receptor: component of translation machinery. Proc. Natl. Acad. Sci. U S A 1992, 89:4368-4372.
-
(1992)
Proc. Natl. Acad. Sci. U S A
, vol.89
, pp. 4368-4372
-
-
Auth, D.1
Brawerman, G.2
-
35
-
-
0030600537
-
Analysis of nuclear localization of laminin binding protein precursor p40 (LBP/p40)
-
Sato M., Kinoshita K., Kaneda Y., Saeki Y., Iwamatsu A., Tanaka K. Analysis of nuclear localization of laminin binding protein precursor p40 (LBP/p40). Biochem. Biophys. Res. Commun. 1996, 229:896-901.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.229
, pp. 896-901
-
-
Sato, M.1
Kinoshita, K.2
Kaneda, Y.3
Saeki, Y.4
Iwamatsu, A.5
Tanaka, K.6
-
36
-
-
41249088465
-
Crystal structure of the human laminin receptor precursor
-
Jamieson K.V., Wu J., Hubbard S.R., Meruelo D. Crystal structure of the human laminin receptor precursor. J. Biol. Chem. 2008, 283:3002-3005.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 3002-3005
-
-
Jamieson, K.V.1
Wu, J.2
Hubbard, S.R.3
Meruelo, D.4
-
37
-
-
78650418551
-
Structure-guided identification of a laminin binding site on the laminin receptor precursor
-
Jamieson K.V., Hubbard S.R., Meruelo D. Structure-guided identification of a laminin binding site on the laminin receptor precursor. J. Mol. Biol. 2010, 405:24-32.
-
(2010)
J. Mol. Biol.
, vol.405
, pp. 24-32
-
-
Jamieson, K.V.1
Hubbard, S.R.2
Meruelo, D.3
-
38
-
-
78650414544
-
Extraribosomal functions associated with the C terminus of the 37/67kDa laminin receptor are required for maintaining cell viability
-
Scheiman J., Jamieson K.V., Ziello J., Tseng J.C., Meruelo D. Extraribosomal functions associated with the C terminus of the 37/67kDa laminin receptor are required for maintaining cell viability. Cell Death Diff. 2010, 1:e42.
-
(2010)
Cell Death Diff.
, vol.1
-
-
Scheiman, J.1
Jamieson, K.V.2
Ziello, J.3
Tseng, J.C.4
Meruelo, D.5
-
39
-
-
79251569266
-
Interactions between laminin receptor and the cytoskeleton during translation and cell motility
-
Venticinque L., Jamieson K.V., Meruelo D. Interactions between laminin receptor and the cytoskeleton during translation and cell motility. PLoS One 2011, 6:e15895.
-
(2011)
PLoS One
, vol.6
-
-
Venticinque, L.1
Jamieson, K.V.2
Meruelo, D.3
-
40
-
-
34250836327
-
The multifunctional nucleolus
-
Boisvert F.M., van Koningsbruggen S., Navascues J., Lamond A.I. The multifunctional nucleolus. Nat. Rev. Mol. Cell Biol. 2007, 8:574-585.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 574-585
-
-
Boisvert, F.M.1
van Koningsbruggen, S.2
Navascues, J.3
Lamond, A.I.4
-
41
-
-
34948859424
-
Identification of a common subnuclear localization signal
-
Mekhail K., Rivero-Lopez L., Al-Masri A., Brandon C., Khacho M., Lee S. Identification of a common subnuclear localization signal. Mol. Biol. Cell 2007, 18:3966-3977.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 3966-3977
-
-
Mekhail, K.1
Rivero-Lopez, L.2
Al-Masri, A.3
Brandon, C.4
Khacho, M.5
Lee, S.6
|