37-kDa laminin receptor precursor mediates GnRH-II-induced MMP-2 expression and invasiveness in ovarian cancer cells

Molecular Endocrinology

Volumn 25, Issue 2, 2011, Pages 327-338

  Poon, Song Ling ^a   Klausen, Christian ^a   Hammond, Geoffrey L ^a   Leung, Peter C K ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GELATINASE B; GONADORELIN; LAMININ; LAMININ RECEPTOR; MATRIGEL; MESSENGER RNA; SMALL INTERFERING RNA;

ARTICLE; CANCER CELL; CELL ADHESION; CELL INVASION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CELL ADHESION; CELL LINE, TUMOR; CELL PROLIFERATION; COLLAGEN; DRUG COMBINATIONS; FEMALE; GENE EXPRESSION; GONADOTROPIN-RELEASING HORMONE; HUMANS; LAMININ; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; OVARIAN NEOPLASMS; PROTEIN PRECURSORS; PROTEOGLYCANS; RECEPTORS, LAMININ; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 79951694549     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2010-0334     Document Type: Article

References (53)

1. So WK, Cheng JC, Poon SL, Leung PC 2008 Gonadotropin-releasing hormone and ovarian cancer: a functional and mechanistic overview. FEBS J 275:5496-5511
2. Cheung LW, Wong AS 2008 Gonadotropin-releasing hormone: GnRH receptor signaling in extrapituitary tissues. FEBS J 275:5479-5495
3. Chen CL, Cheung LW, Lau MT, Choi JH, Auersperg N, Wang HS, Wong AS, Leung PC 2007 Differential role of gonadotropin-releasing hormone on human ovarian epithelial cancer cell invasion. Endocrine 31:311-320 (Pubitemid 47574986)
4. Poon SL, Hammond GT, Leung PC 2009 Epidermal growth factor-induced GnRH-II synthesis contributes to ovarian cancer cell invasion. Mol Endocrinol 23:1646-1656
5. Roy R, Yang J, Moses MA 2009 Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer. J Clin Oncol 27:5287-5297
6. Hijova E 2005 Matrix metalloproteinases: their biological functions and clinical implications. Bratisl Lek Listy 106:127-132
7. Schmalfeldt B, Prechtel D, Harting K, Späthe K, Rutke S, Konik E, Fridman R, Berger U, Schmitt M, Kuhn W, Lengyel E 2001 Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer. Clin Cancer Res 7:2396-2404
8. Murthi P, Barker G, Nowell CJ, Rice GE, Baker MS, Kalionis B, Quinn MA 2004 Plasminogen fragmentation and increased production of extracellular matrix-degrading proteinases are associated with serous epithelial ovarian cancer progression. Gynecol Oncol 92:80-88 (Pubitemid 38147375)
9. Kenny HA, Kaur S, Coussens LM, Lengyel E 2008 The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin. J Clin Invest 118:1367-1379 (Pubitemid 351500430)
10. Roomi MW, Monterrey JC, Kalinovsky T, Rath M, Niedzwiecki A 2010 In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors. Oncol Rep 23:605-614
11. Agarwal A, Covic L, Sevigny LM, Kaneider NC, Lazarides K, Azabdaftari G, Sharifi S, Kuliopulos A 2008 Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer. Mol Cancer Ther 7:2746-2757
12. Cheung LW, Leung PC, Wong AS 2006 Gonadotropin-releasing hormone promotes ovarian cancer cell invasiveness through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9. Cancer Res 66:10902-10910 (Pubitemid 44876988)
13. Berno V, Porrini D, Castiglioni F, Campiglio M, Casalini P, Pupa SM, Balsari A, Ménard S, Tagliabue E 2005 The 67 kDa laminin receptor increases tumor aggressiveness by remodeling laminin-1. Endocr Relat Cancer 12:393-406 (Pubitemid 40896454)
14. Givant-Horwitz V, Davidson B, Reich R 2004 Laminin-induced signaling in tumor cells: the role of the M(r) 67,000 laminin receptor. Cancer Res 64:3572-3579 (Pubitemid 38657934)
15. Romanov VI, Wrathall LS, Simmons TD, Pinto da Silva P, Sobel ME 1995 Protein synthesis is required for laminin-induced expression of the 67-kDa laminin receptor and its 37-kDa precursor. Biochem Biophys Res Commun 208:637-643
16. Rao CN, Castronovo V, Schmitt MC, Wewer UM, Claysmith AP, Liotta LA, Sobel ME 1989 Evidence for a precursor of the high-affinity metastasis- associated murine laminin receptor. Biochemistry 28:7476-7486 (Pubitemid 19227388)
17. Nelson J, McFerran NV, Pivato G, Chambers E, Doherty C, Steele D, Timson DJ 2008 The 67 kDa laminin receptor: structure, function and role in disease. Biosci Rep 28:33-48
18. Liu L, Sun L, Zhao P, Yao L, Jin H, Liang S, Wang Y, Zhang D, Pang Y, Shi Y, Chai N, Zhang H, Zhang H 2010 Hypoxia promotes metastasis in human gastric cancer by up-regulating the 67-kDa laminin receptor. Cancer Sci 101:1653-1660
19. Satoh K, Narumi K, Abe T, Sakai T, Kikuchi T, Tanaka M, Shimo-Oka T, Uchida M, Tezuka F, Isemura M, Nukiwa T 1999 Diminution of 37-kDa laminin binding protein expression reduces tumour formation of murine lung cancer cells. Br J Cancer 80:1115-1122 (Pubitemid 29264068)
20. Canfield SM, Khakoo AY 1999 The nonintegrin laminin binding protein (p67 LBP) is expressed on a subset of activated human T lymphocytes and, together with the integrin very late activation antigen-6, mediates avid cellular adherence to laminin. J Immunol 163:3430-3440 (Pubitemid 29431847)
21. Mafune K, Ravikumar TS 1992 Anti-sense RNA of 32-kDa laminin-binding protein inhibits attachment and invasion of a human colon carcinoma cell line. J Surg Res 52:340-346
22. Vande Broek I, Vanderkerken K, De Greef C, Asosingh K, Straetmans N, Van Camp B, Van Riet I 2001 Laminin-1-induced migration of multiple myeloma cells involves the high-affinity 67 kD laminin receptor. Br J Cancer 85:1387-1395 (Pubitemid 33081937)
23. Tanaka M, Narumi K, Isemura M, Abe M, Sato Y, Abe T, Saijo Y, Nukiwa T, Satoh K 2000 Expression of the 37-kDa laminin binding protein in murine lung tumor cell correlates with tumor angiogenesis. Cancer Lett 153:161-168 (Pubitemid 30209858)
24. Givant-Horwitz V, Davidson B, Reich R 2005 Laminin-induced signaling in tumor cells. Cancer Lett 223:1-10 (Pubitemid 40693705)
25. Hundt C, Peyrin JM, Haïk S, Gauczynski S, Leucht C, Rieger R, Riley ML, Deslys JP, Dormont D, Lasmézas CI, Weiss S 2001 Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor. EMBO J 20:5876-5886 (Pubitemid 33049263)
26. Castronovo V, Taraboletti G, Sobel ME 1991 Functional domains of the 67-kDa laminin receptor precursor. J Biol Chem 266:20440-20446 (Pubitemid 21908479)
27. Castronovo V, Taraboletti G, Sobel ME 1991 Laminin receptor complementary DNA-deduced synthetic peptide inhibits cancer cell attachment to endothelium. Cancer Res 51:5672-5678
28. Magnifico A, Tagliabue E, Butó S, Ardini E, Castronovo V, Colnaghi MI, Ménard S 1996 Peptide G, containing the binding site of the 67-kDa laminin receptor, increases and stabilizes laminin binding to cancer cells. J Biol Chem 271:31179-31184 (Pubitemid 26408560)
29. Chen A, Ganor Y, Rahimipour S, Ben-Aroya N, Koch Y, Levite M 2002 The neuropeptides GnRH-II and GnRH-I are produced by human T cells and trigger laminin receptor gene expression, adhesion, chemotaxis and homing to specific organs. Nat Med 8:1421-1426 (Pubitemid 36019427)
30. Ardini E, Sporchia B, Pollegioni L, Modugno M, Ghirelli C, Castiglioni F, Tagliabue E, Ménard S 2002 Identification of a novel function for 67-kDa laminin receptor: increase in laminin degradation rate and release of motility fragments. Cancer Res 62:1321-1325 (Pubitemid 34407786)
31. Serin IS, Tanriverdi F, Ata CD, Akalin H, Ozcelik B, Ozkul Y, Kelestimur F 2010 GnRH-II mRNA expression in tumor tissue and peripheral blood mononuclear cells (PBMCs) in patients with malignant and benign ovarian tumors. Eur J Obstet Gynecol Reprod Biol 149:92-96
32. Wilkinson SJ, Kucukmetin A, Cross P, Darby S, Gnanapragasam VJ, Calvert AH, Robson CN, Edmondson RJ 2008 Expression of gonadotrophin releasing hormone receptor I is a favorable prognostic factor in epithelial ovarian cancer. Hum Pathol 39:1197-1204
33. van den Brûle FA, Berchuck A, Bast RC, Liu FT, Gillet C, Sobel ME, Castronovo V 1994 Differential expression of the 67-kD laminin receptor and 31-kD human laminin-binding protein in human ovarian carcinomas. Eur J Cancer 30A:1096-1099
34. van den Brûle FA, Castronovo V, Ménard S, Giavazzi R, Marzola M, Belotti D, Taraboletti G 1996 Expression of the 67 kD laminin receptor in human ovarian carcinomas as defined by a monoclonal antibody, MLuC5. Eur J Cancer 32A:1598-1602 (Pubitemid 26279130)
35. Ménard S, Castronovo V, Tagliabue E, Sobel ME 1997 New insights into the metastasis-associated 67 kD laminin receptor. J Cell Biochem 67:155-165 (Pubitemid 27431160)
36. Ménard S, Tagliabue E, Colnaghi MI 1998 The 67 kDa laminin receptor as a prognostic factor in human cancer. Breast Cancer Res Treat 52:137-145 (Pubitemid 29056091)
37. Engbring JA, Kleinman HK 2003 The basement membrane matrix in malignancy. J Pathol 200:465-470 (Pubitemid 36818246)
38. Patarroyo M, Tryggvason K, Virtanen I 2002 Laminin isoforms in tumor invasion, angiogenesis and metastasis. Semin Cancer Biol 12:197-207 (Pubitemid 34833063)
39. Ekblom P, Lonai P, Talts JF 2003 Expression and biological role of laminin-1. Matrix Biol 22:35-47 (Pubitemid 36444505)
40. Määttä M, Bützow R, Luostarinen J, Petäjäniemi N, Pihlajaniemi T, Salo S, Miyazaki K, Autio-Harmainen H, Virtanen I 2005 Differential expression of laminin isoforms in ovarian epithelial carcinomas suggesting different origin and providing tools for differential diagnosis. J Histochem Cytochem 53:1293-1300 (Pubitemid 41331127)
41. Kuwashima Y, Uehara T, Kurosumi M, Kishi K, Shiromizu K, Matsuzawa M, Takayama S 1995 Basement membrane status in undifferentiated carcinomas of the ovary. Immunohistochemical distribution of type IV collagen and laminin. Eur J Gynaecol Oncol 16:181-186
42. Byers LJ, Osborne JL, Carson LF, Carter JR, Haney AF, Weinberg JB, Ramakrishnan S 1995 Increased levels of laminin in ascitic fluid of patients with ovarian cancer. Cancer Lett 88:67-72
43. Capo-Chichi CD, Smith ER, Yang DH, Roland IH, Vanderveer L, Cohen C, Hamilton TC, Godwin AK, Xu XX 2002 Dynamic alterations of the extracellular environment of ovarian surface epithelial cells in premalignant transformation, tumorigenicity, and metastasis. Cancer 95:1802-1815
44. Sasaki T, Fässler R, Hohenester E 2004 Laminin: the crux of basement membrane assembly. J Cell Biol 164:959-963 (Pubitemid 38429121)
45. Ardini E, Tagliabue E, Magnifico A, Butò S, Castronovo V, Colnaghi MI, Ménard S 1997 Co-regulation and physical association of the 67-kDa monomeric laminin receptor and the alpha6beta4 integrin. J Biol Chem 272:2342-2345 (Pubitemid 27058520)
46. Miyamoto S, Teramoto H, Coso OA, Gutkind JS, Burbelo PD, Akiyama SK, Yamada KM 1995 Integrin function: molecular hierarchies of cytoskeletal and signaling molecules. J Cell Biol 131:791-805
47. Hood JD, Cheresh DA 2002 Role of integrins in cell invasion and migration. Nat Rev Cancer 2:91-100 (Pubitemid 37328796)
48. Kleinman HK, Koblinski J, Lee S, Engbring J 2001 Role of basement membrane in tumor growth and metastasis. Surg Oncol Clin N Am 10:329-338, ix
49. Sato H, Takino T, Okada Y, Cao J, Shinagawa A, Yamamoto E, Seiki M 1994 A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature 370:61-65 (Pubitemid 24216953)
50. Strongin AY, Collier I, Bannikov G, Marmer BL, Grant GA, Goldberg GI 1995 Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J Biol Chem 270:5331-5338
51. Poon SL, Lau M-T, Hammond GL, Leung PCK 2011 Gonadotropin-releasing hormone-II increases membrane type I metalloproteinase production via β-catenin signaling in ovarian cancer cells. Endocrinology 10.1210/en.2010-0942
52. Leung EH, Leung PC, Auersperg N 2001 Differentiation and growth potential of human ovarian surface epithelial cells expressing temperature-sensitive SV40 T antigen. In Vitro Cell Dev Biol Anim 37:515-521 (Pubitemid 32973240)
53. Ardini E, Pesole G, Tagliabue E, Magnifico A, Castronovo V, Sobel ME, Colnaghi MI, Ménard S 1998 The 67-kDa laminin receptor originated from a ribosomal protein that acquired a dual function during evolution. Mol Biol Evol 15:1017-1025 (Pubitemid 28364455)