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Volumn 5, Issue 12, 2013, Pages 867-883

Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues

Author keywords

Aging; Chromatin; Epigenetics; Transposable elements

Indexed keywords

DEOXYRIBONUCLEASE; MESSENGER RNA; MICROSATELLITE DNA;

EID: 84891506556     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100621     Document Type: Article
Times cited : (254)

References (69)
  • 1
    • 70349859881 scopus 로고    scopus 로고
    • DNA damage, aging, and cancer
    • Hoeijmakers JH. DNA damage, aging, and cancer. N Engl J Med 2009; 361:1475-1485.
    • (2009) N Engl J Med , vol.361 , pp. 1475-1485
    • Hoeijmakers, J.H.1
  • 2
    • 45449083227 scopus 로고    scopus 로고
    • DNA double-strand breaks: a potential causative factor for mammalian aging?
    • Li H, Mitchell JR, Hasty P. DNA double-strand breaks: a potential causative factor for mammalian aging? Mech Ageing Dev 2008; 129:416-424.
    • (2008) Mech Ageing Dev , vol.129 , pp. 416-424
    • Li, H.1    Mitchell, J.R.2    Hasty, P.3
  • 3
    • 34548150187 scopus 로고    scopus 로고
    • The role of nuclear architecture in genomic instability and ageing
    • Oberdoerffer P, Sinclair DA. The role of nuclear architecture in genomic instability and ageing. Nat. Rev. Mol. Cell. Biol. 2007; 8:692-702.
    • (2007) Nat. Rev. Mol. Cell. Biol. , vol.8 , pp. 692-702
    • Oberdoerffer, P.1    Sinclair, D.A.2
  • 4
    • 84867907645 scopus 로고    scopus 로고
    • The great unravelling: chromatin as a modulator of the aging process
    • O'Sullivan RJ, Karlseder J. The great unravelling: chromatin as a modulator of the aging process. Trends Biochem Sci 2012; 37:466-476.
    • (2012) Trends Biochem Sci , vol.37 , pp. 466-476
    • O'Sullivan, R.J.1    Karlseder, J.2
  • 5
    • 84860879005 scopus 로고    scopus 로고
    • Human transposon tectonics
    • Burns KH, Boeke JD. Human transposon tectonics. Cell 2012; 149:740-752.
    • (2012) Cell , vol.149 , pp. 740-752
    • Burns, K.H.1    Boeke, J.D.2
  • 7
    • 80051997952 scopus 로고    scopus 로고
    • Dynamic interactions between transposable elements and their hosts
    • Levin HL, Moran JV. Dynamic interactions between transposable elements and their hosts. Nat Rev Genet 2011; 12:615-627.
    • (2011) Nat Rev Genet , vol.12 , pp. 615-627
    • Levin, H.L.1    Moran, J.V.2
  • 8
    • 84875313166 scopus 로고    scopus 로고
    • Revisiting the evolution of mouse LINE-1 in the genomic era
    • Sookdeo A, Hepp CM, McClure MA, Boissinot S. Revisiting the evolution of mouse LINE-1 in the genomic era. Mob DNA 2013; 4:3.
    • (2013) Mob DNA , vol.4 , pp. 3
    • Sookdeo, A.1    Hepp, C.M.2    McClure, M.A.3    Boissinot, S.4
  • 10
    • 67650142756 scopus 로고    scopus 로고
    • Dynamics of transposable elements: towards a community ecology of the genome
    • Venner S, Feschotte C, Biemont C. Dynamics of transposable elements: towards a community ecology of the genome. Trends Genet 2009; 25:317-323.
    • (2009) Trends Genet , vol.25 , pp. 317-323
    • Venner, S.1    Feschotte, C.2    Biemont, C.3
  • 11
    • 84874957633 scopus 로고    scopus 로고
    • How do mammalian transposons induce genetic variation? A conceptual framework: the age, structure, allele frequency, and genome context of transposable elements may define their wide-ranging biological impacts
    • Akagi K, Li J, Symer DE. How do mammalian transposons induce genetic variation? A conceptual framework: the age, structure, allele frequency, and genome context of transposable elements may define their wide-ranging biological impacts. Bioessays 2013; 35:397-407.
    • (2013) Bioessays , vol.35 , pp. 397-407
    • Akagi, K.1    Li, J.2    Symer, D.E.3
  • 12
    • 33646814901 scopus 로고    scopus 로고
    • Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells
    • Belgnaoui SM, Gosden RG, Semmes OJ, Haoudi A. Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells. Cancer Cell Int 2006; 6:13.
    • (2006) Cancer Cell Int , vol.6 , pp. 13
    • Belgnaoui, S.M.1    Gosden, R.G.2    Semmes, O.J.3    Haoudi, A.4
  • 13
    • 33645068168 scopus 로고    scopus 로고
    • The human LINE-1 retrotransposon creates DNA double-strand breaks
    • Gasior SL, Wakeman TP, Xu B, Deininger PL. The human LINE-1 retrotransposon creates DNA double-strand breaks. J Mol Biol 2006; 357:1383-1393.
    • (2006) J Mol Biol , vol.357 , pp. 1383-1393
    • Gasior, S.L.1    Wakeman, T.P.2    Xu, B.3    Deininger, P.L.4
  • 15
    • 84862507347 scopus 로고    scopus 로고
    • Active human retrotransposons: variation and disease
    • Hancks DC, Kazazian HH, Jr. Active human retrotransposons: variation and disease. Curr Opin Genet Dev 2012; 22:191-203.
    • (2012) Curr Opin Genet Dev , vol.22 , pp. 191-203
    • Hancks, D.C.1    Kazazian Jr., H.H.2
  • 22
    • 84875999688 scopus 로고    scopus 로고
    • Long interspersed element-1 (LINE-1): passenger or driver in human neoplasms?
    • Rodic N, Burns KH. Long interspersed element-1 (LINE-1): passenger or driver in human neoplasms? PLoS Genet 2013; 9:e1003402.
    • (2013) PLoS Genet , vol.9
    • Rodic, N.1    Burns, K.H.2
  • 29
    • 55549096355 scopus 로고    scopus 로고
    • Murine endogenous retroviruses
    • Stocking C, Kozak CA. Murine endogenous retroviruses. Cell Mol Life Sci 2008; 65:3383-3398.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3383-3398
    • Stocking, C.1    Kozak, C.A.2
  • 33
    • 77953081850 scopus 로고    scopus 로고
    • A LINE-1 component to human aging: do LINE elements exact a longevity cost for evolutionary advantage?
    • St Laurent G, 3rd, Hammell N, McCaffrey TA. A LINE-1 component to human aging: do LINE elements exact a longevity cost for evolutionary advantage? Mech Ageing Dev 2010; 131:299-305.
    • (2010) Mech Ageing Dev , vol.131 , pp. 299-305
    • St Laurent III, G.1    Hammell, N.2    McCaffrey, T.A.3
  • 34
    • 84879890507 scopus 로고    scopus 로고
    • Functional impact of the human mobilome
    • Babatz TD, Burns KH. Functional impact of the human mobilome. Curr Opin Genet Dev 2013; 23:264-270.
    • (2013) Curr Opin Genet Dev , vol.23 , pp. 264-270
    • Babatz, T.D.1    Burns, K.H.2
  • 36
    • 77957814604 scopus 로고    scopus 로고
    • Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres
    • O'Sullivan RJ, Kubicek S, Schreiber SL, Karlseder J. Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres. Nat Struct Mol Biol 2010; 17:1218-1225.
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 1218-1225
    • O'Sullivan, R.J.1    Kubicek, S.2    Schreiber, S.L.3    Karlseder, J.4
  • 39
    • 33846090789 scopus 로고    scopus 로고
    • Accumulation of senescent cells in mitotic tissue of aging primates
    • Jeyapalan JC, Ferreira M, Sedivy JM, Herbig U. Accumulation of senescent cells in mitotic tissue of aging primates. Mech Ageing Dev 2007; 128:36-44.
    • (2007) Mech Ageing Dev , vol.128 , pp. 36-44
    • Jeyapalan, J.C.1    Ferreira, M.2    Sedivy, J.M.3    Herbig, U.4
  • 41
    • 84855496921 scopus 로고    scopus 로고
    • Retrotransposition is associated with genome instability during chronological aging
    • Maxwell PH, Burhans WC, Curcio MJ. Retrotransposition is associated with genome instability during chronological aging. Proc Natl Acad Sci U S A 2011; 108:20376-20381.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 20376-20381
    • Maxwell, P.H.1    Burhans, W.C.2    Curcio, M.J.3
  • 44
    • 40449139336 scopus 로고    scopus 로고
    • Mammalian non-LTR retrotransposons: for better or worse, in sickness and in health
    • Belancio VP, Hedges DJ, Deininger P. Mammalian non-LTR retrotransposons: for better or worse, in sickness and in health. Genome Res 2008; 18:343-358.
    • (2008) Genome Res , vol.18 , pp. 343-358
    • Belancio, V.P.1    Hedges, D.J.2    Deininger, P.3
  • 46
    • 0242329885 scopus 로고    scopus 로고
    • Human Alu element retrotransposition induced by genotoxic stress
    • Hagan CR, Sheffield RF, Rudin CM. Human Alu element retrotransposition induced by genotoxic stress. Nat. Genet. 2003; 35:219-220.
    • (2003) Nat. Genet. , vol.35 , pp. 219-220
    • Hagan, C.R.1    Sheffield, R.F.2    Rudin, C.M.3
  • 47
    • 19644391725 scopus 로고    scopus 로고
    • Structural and functional characterization of noncoding repetitive RNAs transcribed in stressed human cells
    • Valgardsdottir R, Chiodi I, Giordano M, Cobianchi F, Riva S, Biamonti G. Structural and functional characterization of noncoding repetitive RNAs transcribed in stressed human cells. Mol. Biol. Cell 2005; 16:2597-2604.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 2597-2604
    • Valgardsdottir, R.1    Chiodi, I.2    Giordano, M.3    Cobianchi, F.4    Riva, S.5    Biamonti, G.6
  • 49
    • 79955552036 scopus 로고    scopus 로고
    • Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition
    • Dai L, Huang Q, Boeke JD. Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition. BMC Biochem 2011; 12:18.
    • (2011) BMC Biochem , vol.12 , pp. 18
    • Dai, L.1    Huang, Q.2    Boeke, J.D.3
  • 50
    • 0025107556 scopus 로고
    • A deletion of the human betaglobin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus
    • Forrester WC, Epner E, Driscoll MC, Enver T, Brice M, Papayannopoulou T, Groudine M. A deletion of the human betaglobin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus. Genes Dev 1990; 4:1637-1649.
    • (1990) Genes Dev , vol.4 , pp. 1637-1649
    • Forrester, W.C.1    Epner, E.2    Driscoll, M.C.3    Enver, T.4    Brice, M.5    Papayannopoulou, T.6    Groudine, M.7
  • 53
    • 77957739239 scopus 로고    scopus 로고
    • Positive regulation of euchromatic gene expression by HP1
    • Piacentini L, Pimpinelli S. Positive regulation of euchromatic gene expression by HP1. Fly (Austin) 2010; 4:299-301.
    • (2010) Fly (Austin) , vol.4 , pp. 299-301
    • Piacentini, L.1    Pimpinelli, S.2
  • 55
    • 80855144457 scopus 로고    scopus 로고
    • Nuclear protein accumulation in cellular senescence and organismal aging revealed with a novel single-cell resolution fluorescence microscopy assay
    • De Cecco M, Jeyapalan J, Zhao X, Tamamori-Adachi M, Sedivy JM. Nuclear protein accumulation in cellular senescence and organismal aging revealed with a novel single-cell resolution fluorescence microscopy assay. Aging (Albany NY) 2011; 3:955-967.
    • (2011) Aging (Albany NY) , vol.3 , pp. 955-967
    • De Cecco, M.1    Jeyapalan, J.2    Zhao, X.3    Tamamori-Adachi, M.4    Sedivy, J.M.5
  • 56
    • 40349098062 scopus 로고    scopus 로고
    • macroH2A1-dependent silencing of endogenous murine leukemia viruses
    • Changolkar LN, Singh G, Pehrson JR. macroH2A1-dependent silencing of endogenous murine leukemia viruses. Mol. Cell. Biol. 2008; 28:2059-2065.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 2059-2065
    • Changolkar, L.N.1    Singh, G.2    Pehrson, J.R.3
  • 57
    • 79960058683 scopus 로고    scopus 로고
    • Amplification-free library preparation for paired-end Illumina sequencing
    • Kozarewa I, Turner DJ. Amplification-free library preparation for paired-end Illumina sequencing. Methods Mol. Biol. 2011; 733:257-266.
    • (2011) Methods Mol. Biol. , vol.733 , pp. 257-266
    • Kozarewa, I.1    Turner, D.J.2
  • 61
    • 77955801615 scopus 로고    scopus 로고
    • Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
    • Goecks J, Nekrutenko A, Taylor J. Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences. Genome Biol. 2010; 11:R86.
    • (2010) Genome Biol , vol.11
    • Goecks, J.1    Nekrutenko, A.2    Taylor, J.3
  • 62
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-Seq
    • Trapnell C, Pachter L, Salzberg SL. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 2009; 25:1105-1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 64
    • 77953935308 scopus 로고    scopus 로고
    • Estimating enrichment of repetitive elements from high-throughput sequence data
    • Day DS, Luquette LJ, Park PJ, Kharchenko PV. Estimating enrichment of repetitive elements from high-throughput sequence data. Genome Biol. 2010; 11:R69.
    • (2010) Genome Biol , vol.11
    • Day, D.S.1    Luquette, L.J.2    Park, P.J.3    Kharchenko, P.V.4
  • 65
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B, Trapnell C, Pop M, Salzberg SL. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 2009; 10:R25.
    • (2009) Genome Biol , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 66
    • 50649089207 scopus 로고    scopus 로고
    • RNAseq: an assessment of technical reproducibility and comparison with gene expression arrays
    • Marioni JC, Mason CE, Mane SM, Stephens M, Gilad Y. RNAseq: an assessment of technical reproducibility and comparison with gene expression arrays. Genome Res. 2008; 18:1509-1517.
    • (2008) Genome Res , vol.18 , pp. 1509-1517
    • Marioni, J.C.1    Mason, C.E.2    Mane, S.M.3    Stephens, M.4    Gilad, Y.5
  • 67
    • 75249087100 scopus 로고    scopus 로고
    • edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson MD, McCarthy DJ, Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 2010; 26:139-140.
    • (2010) Bioinformatics , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 68
    • 77958471357 scopus 로고    scopus 로고
    • Differential expression analysis for sequence count data
    • Anders S, Huber W. Differential expression analysis for sequence count data. Genome. Biol. 2010; 11:R106.
    • (2010) Genome. Biol. , vol.11
    • Anders, S.1    Huber, W.2
  • 69
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc. Natl. Acad. Sci. USA 2003; 100:9440-9445.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.