-
1
-
-
41349090663
-
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
-
Michishita, E., McCord, R.A., Berber, E., Kioi, M., Padilla-Nash, H., Damian, M., Cheung, P., Kusumoto, R., Kawahara, T.L., Barrett, J.C. et al. (2008) SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature, 452, 492-496.
-
(2008)
Nature
, vol.452
, pp. 492-496
-
-
Michishita, E.1
McCord, R.A.2
Berber, E.3
Kioi, M.4
Padilla-Nash, H.5
Damian, M.6
Cheung, P.7
Kusumoto, R.8
Kawahara, T.L.9
Barrett, J.C.10
-
2
-
-
69249229772
-
The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability
-
Yang, B., Zwaans, B.M., Eckersdorff, M. and Lombard, D.B. (2009) The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability. Cell Cycle, 8, 2662-2663.
-
(2009)
Cell Cycle
, vol.8
, pp. 2662-2663
-
-
Yang, B.1
Zwaans, B.M.2
Eckersdorff, M.3
Lombard, D.B.4
-
3
-
-
69249221533
-
Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
-
Michishita, E., McCord, R.A., Boxer, L.D., Barber, M.F., Hong, T., Gozani, O. and Chua, K.F. (2009) Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6. Cell Cycle, 8, 2664-2666.
-
(2009)
Cell Cycle
, vol.8
, pp. 2664-2666
-
-
Michishita, E.1
McCord, R.A.2
Boxer, L.D.3
Barber, M.F.4
Hong, T.5
Gozani, O.6
Chua, K.F.7
-
4
-
-
77956550868
-
Human SIRT6 promotes DNA end resection through CtIP deacetylation
-
Kaidi, A., Weinert, B.T., Choudhary, C. and Jackson, S.P. (2010) Human SIRT6 promotes DNA end resection through CtIP deacetylation. Science, 329, 1348-1353.
-
(2010)
Science
, vol.329
, pp. 1348-1353
-
-
Kaidi, A.1
Weinert, B.T.2
Choudhary, C.3
Jackson, S.P.4
-
5
-
-
79959363092
-
SIRT6 promotes DNA repair under stress by activating PARP1
-
Mao, Z., Hine, C., Tian, X., Van Meter, M., Au, M., Vaidya, A., Seluanov, A. and Gorbunova, V. (2011) SIRT6 promotes DNA repair under stress by activating PARP1. Science, 332, 1443-1446.
-
(2011)
Science
, vol.332
, pp. 1443-1446
-
-
Mao, Z.1
Hine, C.2
Tian, X.3
Van Meter, M.4
Au, M.5
Vaidya, A.6
Seluanov, A.7
Gorbunova, V.8
-
6
-
-
39649100868
-
Regulation of SIRT6 protein levels by nutrient availability
-
Kanfi, Y., Shalman, R., Peshti, V., Pilosof, S.N., Gozlan, Y.M., Pearson, K.J., Lerrer, B., Moazed, D., Marine, J.C., de Cabo, R. et al. (2008) Regulation of SIRT6 protein levels by nutrient availability. FEBS Lett., 582, 543-548.
-
(2008)
FEBS Lett
, vol.582
, pp. 543-548
-
-
Kanfi, Y.1
Shalman, R.2
Peshti, V.3
Pilosof, S.N.4
Pearson, M.G.Y.5
Lerrer, K.J.6
Moazed, D.B.7
Marine, J.C.8
De Cabo, R.9
-
7
-
-
77953244349
-
SIRT6 protects against pathological damage caused by diet-induced obesity
-
Kanfi, Y., Peshti, V., Gil, R., Naiman, S., Nahum, L., Levin, E., Kronfeld-Schor, N. and Cohen, H.Y. (2009) SIRT6 protects against pathological damage caused by diet-induced obesity. Aging Cell, 9, 162-732.
-
(2009)
Aging Cell
, vol.9
, pp. 162-732
-
-
Kanfi, Y.1
Peshti, V.2
Gil, R.3
Naiman, S.4
Nahum, L.5
Levin, E.6
Kronfeld-Schor, N.7
Cohen, H.Y.8
-
8
-
-
78650724968
-
Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity
-
Schwer, B., Schumacher, B., Lombard, D.B., Xiao, C., Kurtev, M.V., Gao, J., Schneider, J.I., Chai, H., Bronson, R.T., Tsai, L.H. et al. (2010) Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity. Proc. Natl Acad. Sci. USA, 107, 21790-21794.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 21790-21794
-
-
Schwer, B.1
Schumacher, B.2
Lombard, D.B.3
Xiao, C.4
Kurtev, M.V.5
Gao, J.6
Schneider, J.I.7
Chai, H.8
Bronson, R.T.9
Tsai, L.H.10
-
9
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
Kanfi, Y., Naiman, S., Amir, G., Peshti, V., Zinman, G., Nahum, L., Bar-Joseph, Z. and Cohen, H.Y. (2012) The sirtuin SIRT6 regulates lifespan in male mice. Nature, 483, 218-221.
-
(2012)
Nature
, vol.483
, pp. 218-221
-
-
Kanfi, Y.1
Naiman, S.2
Amir, G.3
Peshti, V.4
Zinman, G.5
Nahum, L.6
Bar-Joseph, Z.7
Cohen, H.Y.8
-
10
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
Mostoslavsky, R., Chua, K.F., Lombard, D.B., Pang, W.W., Fischer, M.R., Gellon, L., Liu, P., Mostoslavsky, G., Franco, S., Murphy, M.M. et al. (2006) Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell, 124, 315-329.
-
(2006)
Cell
, vol.124
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
-
11
-
-
74549142287
-
The histone deacetylase Sirt6 regulates glucose homeostasis via HIF1alpha
-
Zhong, L., D?Urso, A., Toiber, D., Sebastian, C., Henry, R.E., Vadysirisack, D.D., Guimaraes, A., Marinelli, B., Wikstrom, J.D., Nir, T. et al. (2010) The histone deacetylase Sirt6 regulates glucose homeostasis via HIF1alpha. Cell, 140, 280-293.
-
(2010)
Cell
, vol.140
, pp. 280-293
-
-
Zhong, L.1
Durso, A.2
Toiber, D.3
Sebastian, C.4
Henry, R.E.5
Vadysirisack, D.D.6
Guimaraes, A.7
Marinelli, B.8
Wikstrom, J.D.9
Nir, T.10
-
12
-
-
84870874690
-
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism
-
Sebastian, C., Zwaans, B.M., Silberman, D.M., Gymrek, M., Goren, A., Zhong, L., Ram, O., Truelove, J., Guimaraes, A.R., Toiber, D. et al. (2012) The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Cell, 151, 1185-1199.
-
(2012)
Cell
, vol.151
, pp. 1185-1199
-
-
Sebastian, C.1
Zwaans, B.M.2
Silberman, D.M.3
Gymrek, M.4
Goren, A.5
Zhong, L.6
Ram, O.7
Truelove, J.8
Guimaraes, A.R.9
Toiber, D.10
-
13
-
-
77950035354
-
Functional dissection of SIRT6: Identification of domains that regulate histone deacetylase activity and chromatin localization
-
Tennen, R.I., Berber, E. and Chua, K.F. (2010) Functional dissection of SIRT6: Identification of domains that regulate histone deacetylase activity and chromatin localization. Mech. Ageing Dev., 131, 185-192.
-
(2010)
Mech. Ageing Dev
, vol.131
, pp. 185-192
-
-
Tennen, R.I.1
Berber, E.2
Chua, K.F.3
-
14
-
-
58149090925
-
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span
-
Kawahara, T.L., Michishita, E., Adler, A.S., Damian, M., Berber, E., Lin, M., McCord, R.A., Ongaigui, K.C., Boxer, L.D., Chang, H.Y. et al. (2009) SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell, 136, 62-74.
-
(2009)
Cell
, vol.136
, pp. 62-74
-
-
Kawahara, T.L.1
Michishita, E.2
Adler, A.S.3
Damian, M.4
Berber, E.5
Lin, M.6
McCord, R.A.7
Ongaigui, K.C.8
Boxer, L.D.9
Chang, H.Y.10
-
15
-
-
80052399287
-
SIRT6 is required for maintenance of telomere position effect in human cells
-
Tennen, R.I., Bua, D.J., Wright, W.E. and Chua, K.F. (2011) SIRT6 is required for maintenance of telomere position effect in human cells. Nat. Commun., 2, 433.
-
(2011)
Nat. Commun
, vol.2
, pp. 433
-
-
Tennen, R.I.1
Bua, D.J.2
Wright, W.E.3
Chua, K.F.4
-
16
-
-
66049150672
-
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
-
McCord, R.A., Michishita, E., Hong, T., Berber, E., Boxer, L.D., Kusumoto, R., Guan, S., Shi, X., Gozani, O., Burlingame, A.L. et al. (2009) SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. Aging (Albany NY), 1, 109-121.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 109-121
-
-
McCord, R.A.1
Michishita, E.2
Hong, T.3
Berber, E.4
Boxer, L.D.5
Kusumoto, R.6
Guan, S.7
Shi, X.8
Gozani, O.9
Burlingame, A.L.10
-
17
-
-
79954581231
-
Structure and biochemical functions of SIRT6
-
Pan, P.W., Feldman, J.L., Devries, M.K., Dong, A., Edwards, A.M. and Denu, J.M. (2011) Structure and biochemical functions of SIRT6. J. Biol. Chem., 286, 14575-14587.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 14575-14587
-
-
Pan, P.W.1
Feldman, J.L.2
Devries, M.K.3
Dong, A.4
Edwards, A.M.5
Denu, J.M.6
-
18
-
-
84863696106
-
Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFkappaB Responses
-
Grimley, R., Polyakova, O., Vamathevan, J., McKenary, J., Hayes, B., Patel, C., Smith, J., Bridges, A., Fosberr, A., Bhardwaja, A. et al. (2012) Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFkappaB Responses. PLoS One, 7, e39847.
-
(2012)
PLoS One
, vol.7
-
-
Grimley, R.1
Polyakova, O.2
Vamathevan, J.3
McKenary, J.4
Hayes, B.5
Patel, C.6
Smith, J.7
Bridges, A.8
Fosberr, A.9
Bhardwaja, A.10
-
19
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz, K.T., Bitterman, K.J., Cohen, H.Y., Lamming, D.W., Lavu, S., Wood, J.G., Zipkin, R.E., Chung, P., Kisielewski, A., Zhang, L.L. et al. (2003) Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature, 425, 191-196.
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
-
20
-
-
39549115045
-
Assembly of nucleosomal templates by salt dialysis
-
Lee, K.M. and Narlikar, G. (2001) Assembly of nucleosomal templates by salt dialysis. Curr Protoc Mol Biol., 21, mb2106s54.
-
(2001)
Curr Protoc Mol Biol
, vol.21
-
-
Lee, K.M.1
Narlikar, G.2
-
21
-
-
4944245398
-
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
-
Vaquero, A., Scher, M., Lee, D., Erdjument-Bromage, H., Tempst, P. and Reinberg, D. (2004) Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol. Cell, 16, 93-105.
-
(2004)
Mol. Cell
, vol.16
, pp. 93-105
-
-
Vaquero, A.1
Scher, M.2
Lee, D.3
Erdjument-Bromage, H.4
Tempst, P.5
Reinberg, D.6
-
22
-
-
84875881601
-
SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine
-
Jiang, H., Khan, S., Wang, Y., Charron, G., He, B., Sebastian, C., Du, J., Kim, R., Ge, E., Mostoslavsky, R. et al. (2013) SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine. Nature, 496, 110-113.
-
(2013)
Nature
, vol.496
, pp. 110-113
-
-
Jiang, H.1
Khan, S.2
Wang, Y.3
Charron, G.4
He, B.5
Sebastian, C.6
Du, J.7
Kim, R.8
Ge, E.9
Mostoslavsky, R.10
|