BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo

Cardiovascular Pathology

Volumn 25, Issue 3, 2016, Pages 258-269

  Bultman, Scott J ^a,b   Holley, Darcy Wood ^a   G De Ridder, Gustaaf ^c   Pizzo, Salvatore V ^c   Sidorova, Tatiana N ^d   Murray, Katherine T ^d   Jensen, Brian C ^a   Wang, Zhongjing ^a   Bevilacqua, Ariana ^a   Chen, Xin ^e   Quintana, Megan T ^a   Tannu, Manasi ^a   Rosson, Gary B ^a   Pandya, Kumar ^f   Willis, Monte S ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^f Transviragen   (United States)

Author keywords

Autophagy; BRG1; BRM; Cardiomyocyte; CHOP; GRP78; IRE 1; Mitochondrial dynamics; Mitophagy; SWI SNF complex; Unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; AMYLOID; BAFILOMYCIN A1; BECLIN 1; BRG1 PROTEIN; BRM PROTEIN; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; MITOCHONDRIAL DNA; PROTEIN BNIP3; DNA HELICASE; NUCLEAR PROTEIN; SMARCA2 PROTEIN, MOUSE; SMARCA4 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL METABOLISM; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DISEASE COURSE; HEART AMYLOIDOSIS; HEART FAILURE; HEART FUNCTION; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL DYNAMICS; MITOPHAGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; TRANSTHORACIC ECHOCARDIOGRAPHY; UNFOLDED PROTEIN RESPONSE; ANIMAL; CARDIAC MUSCLE CELL; DISEASE MODEL; METABOLISM; MITOCHONDRION; MUTANT MOUSE STRAIN; PATHOLOGY; PHYSIOLOGY;

ANIMALS; DISEASE MODELS, ANIMAL; DNA HELICASES; HEART FAILURE; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; MICE; MICE, MUTANT STRAINS; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MITOCHONDRIAL DYNAMICS; MYOCYTES, CARDIAC; NUCLEAR PROTEINS; TRANSCRIPTION FACTORS;

EID: 84961990835     PISSN: 10548807     EISSN: 18791336     Source Type: Journal    
DOI: 10.1016/j.carpath.2016.02.004     Document Type: Article

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