Myocardial ER chaperone activation and protein degradation occurs due to synergistic, not individual, cold and hypoxic stress

Biochimie

Volumn 95, Issue 10, 2013, Pages 1897-1908

  Jain, Kanika ^a   Suryakumar, Geetha ^a   Prasad, Rajendra ^a   Singh, Som Nath ^a   Ganju, Lilly ^a  

^a DEFENCE INSTITUTE OF PHYSIOLOGY AND ALLIED SCIENCES   (India)

Author keywords

Chaperones; Cold; ER stress; Heart; Hypobaric hypoxia

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CHAPERONE; HEAT SHOCK PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PHOSPHOTRANSFERASE; PROTEASOME; REACTIVE OXYGEN METABOLITE;

ALTITUDE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CELLULAR STRESS RESPONSE; COLD CLIMATE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENVIRONMENTAL STRESS; HEART MUSCLE; HYPOBARISM; HYPOXIA; INDUCED HYPOTHERMIA; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALIA; RATTUS;

CHAPERONES; COLD; ER STRESS; HEART; HYPOBARIC HYPOXIA;

ANIMALS; ANOXIA; APOPTOSIS; COLD TEMPERATURE; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIPID PEROXIDATION; MALE; MYOCARDIUM; OXIDATION-REDUCTION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN CARBONYLATION; PROTEIN DISULFIDE-ISOMERASES; PROTEIN FOLDING; PROTEOLYSIS; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTOR CHOP; TUNICAMYCIN;

EID: 84883210557     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2013.06.018     Document Type: Article

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