메뉴 건너뛰기




Volumn 173, Issue , 2016, Pages 42-54

Distinct mechanisms of the newborn innate immunity

Author keywords

Adaptive immunity; Immune response; Innate immunity; Microbiome; Newborns; Pro inflammatory cytokines

Indexed keywords

ACUTE PHASE PROTEIN; ADENOSINE; FIBRONECTIN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 18; INTERLEUKIN 23; INTERLEUKIN 4; INTERLEUKIN 6; MANNOSE BINDING LECTIN; POLYPEPTIDE ANTIBIOTIC AGENT; PROSTAGLANDIN E2; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; IMMUNOGLOBULIN G;

EID: 84961825270     PISSN: 01652478     EISSN: 18790542     Source Type: Journal    
DOI: 10.1016/j.imlet.2016.03.009     Document Type: Review
Times cited : (60)

References (198)
  • 3
    • 19044363999 scopus 로고    scopus 로고
    • Innate immunity of the human newborn: distinct cytokine responses to LPS and other Toll-like receptor agonists
    • Levy O. Innate immunity of the human newborn: distinct cytokine responses to LPS and other Toll-like receptor agonists. J. Endotoxin Res. 2005, 11:113-116.
    • (2005) J. Endotoxin Res. , vol.11 , pp. 113-116
    • Levy, O.1
  • 4
    • 33646760920 scopus 로고    scopus 로고
    • Developmental regulation of the immune system
    • Clapp W. Developmental regulation of the immune system. Semin. Perinatol. 2006, 30:69-72.
    • (2006) Semin. Perinatol. , vol.30 , pp. 69-72
    • Clapp, W.1
  • 5
    • 0035858127 scopus 로고    scopus 로고
    • Neonatal and early life vaccinology
    • Siegrist C.A. Neonatal and early life vaccinology. Vaccine 2001, 19:3331-3346.
    • (2001) Vaccine , vol.19 , pp. 3331-3346
    • Siegrist, C.A.1
  • 6
    • 0033166040 scopus 로고    scopus 로고
    • T-cell function in newborn mice and humans
    • Adkins B. T-cell function in newborn mice and humans. Immunol. Today 1999, 20:330-335.
    • (1999) Immunol. Today , vol.20 , pp. 330-335
    • Adkins, B.1
  • 7
    • 84919657877 scopus 로고    scopus 로고
    • The role of the microbiome in immune cell development
    • Salzman N.H. The role of the microbiome in immune cell development. Ann. Allergy Asthma Immunol. 2014, 113:593-598.
    • (2014) Ann. Allergy Asthma Immunol. , vol.113 , pp. 593-598
    • Salzman, N.H.1
  • 9
  • 10
    • 84861659935 scopus 로고    scopus 로고
    • Human milk oligosaccharide consumption by intestinal microbiota
    • (s4)
    • Marcobal A., Sonnenburg J.L. Human milk oligosaccharide consumption by intestinal microbiota. Clin. Microbiol. Infect. 2012, 18:12-15. (s4).
    • (2012) Clin. Microbiol. Infect. , vol.18 , pp. 12-15
    • Marcobal, A.1    Sonnenburg, J.L.2
  • 11
    • 84897138296 scopus 로고    scopus 로고
    • Role of the microbiota in immunity and inflammation
    • Belkaid Y., Hand T.W. Role of the microbiota in immunity and inflammation. Cell 2014, 157:121-141.
    • (2014) Cell , vol.157 , pp. 121-141
    • Belkaid, Y.1    Hand, T.W.2
  • 13
    • 33947150385 scopus 로고    scopus 로고
    • Bacterial imprinting of the neonatal immune system: lessons from maternal cells?
    • Perez P.F., Doré J., Leclerc M., Levenez F., Benyacoub J., Serrant P., et al. Bacterial imprinting of the neonatal immune system: lessons from maternal cells?. Pediatrics 2007, 119:e724-32.
    • (2007) Pediatrics , vol.119 , pp. e724-e732
    • Perez, P.F.1    Doré, J.2    Leclerc, M.3    Levenez, F.4    Benyacoub, J.5    Serrant, P.6
  • 14
    • 84889595600 scopus 로고    scopus 로고
    • Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection
    • Elahi S., Ertelt J.M., Kinder J.M., Jiang T.T., Zhang X., Xin L., et al. Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection. Nature 2013, 504:158-162.
    • (2013) Nature , vol.504 , pp. 158-162
    • Elahi, S.1    Ertelt, J.M.2    Kinder, J.M.3    Jiang, T.T.4    Zhang, X.5    Xin, L.6
  • 15
    • 84860216630 scopus 로고    scopus 로고
    • Microbial exposure during early life has persistent effects on natural killer T cell function
    • Olszak T., An D., Zeissig S., Vera M., Richter J., Franke A., et al. Microbial exposure during early life has persistent effects on natural killer T cell function. Science 2012, 336:489-493.
    • (2012) Science , vol.336 , pp. 489-493
    • Olszak, T.1    An, D.2    Zeissig, S.3    Vera, M.4    Richter, J.5    Franke, A.6
  • 16
    • 84892774558 scopus 로고    scopus 로고
    • Sphingolipids from a symbiotic microbe regulate homeostasis of host intestinal natural killer T cells
    • An D., Oh S.F., Olszak T., Neves J.F., Avci F.Y., Erturk-Hasdemir D., et al. Sphingolipids from a symbiotic microbe regulate homeostasis of host intestinal natural killer T cells. Cell 2014, 156:123-133.
    • (2014) Cell , vol.156 , pp. 123-133
    • An, D.1    Oh, S.F.2    Olszak, T.3    Neves, J.F.4    Avci, F.Y.5    Erturk-Hasdemir, D.6
  • 17
    • 33645843063 scopus 로고    scopus 로고
    • Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells
    • Lotz M., Gütle D., Walther S., Ménard S., Bogdan C., Hornef M.W. Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells. J. Exp. Med. 2006, 203:973-984.
    • (2006) J. Exp. Med. , vol.203 , pp. 973-984
    • Lotz, M.1    Gütle, D.2    Walther, S.3    Ménard, S.4    Bogdan, C.5    Hornef, M.W.6
  • 18
    • 84902996531 scopus 로고    scopus 로고
    • The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice
    • Deshmukh H.S., Liu Y., Menkiti O.R., Mei J., Dai N., O'Leary C.E., et al. The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice. Nat. Med. 2014, 20:524-530.
    • (2014) Nat. Med. , vol.20 , pp. 524-530
    • Deshmukh, H.S.1    Liu, Y.2    Menkiti, O.R.3    Mei, J.4    Dai, N.5    O'Leary, C.E.6
  • 19
    • 0036892895 scopus 로고    scopus 로고
    • Innate immune responses of human neonatal cells to bacteria from the normal gastrointestinal flora
    • Karlsson H., Hessle C., Rudin A. Innate immune responses of human neonatal cells to bacteria from the normal gastrointestinal flora. Infect. Immun. 2002, 70:6688-6696.
    • (2002) Infect. Immun. , vol.70 , pp. 6688-6696
    • Karlsson, H.1    Hessle, C.2    Rudin, A.3
  • 20
    • 22144490199 scopus 로고    scopus 로고
    • An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
    • Mazmanian S.K., Liu C.H., Tzianabos A.O., Kasper D.L. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 2005, 122:107-118.
    • (2005) Cell , vol.122 , pp. 107-118
    • Mazmanian, S.K.1    Liu, C.H.2    Tzianabos, A.O.3    Kasper, D.L.4
  • 21
    • 56749146467 scopus 로고    scopus 로고
    • Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
    • Bouskra D., Brézillon C., Bérard M., Werts C., Varona R., Boneca I.G., et al. Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature 2008, 456:507-510.
    • (2008) Nature , vol.456 , pp. 507-510
    • Bouskra, D.1    Brézillon, C.2    Bérard, M.3    Werts, C.4    Varona, R.5    Boneca, I.G.6
  • 22
    • 33847350541 scopus 로고    scopus 로고
    • Murine neonatal CD4+ cells are poised for rapid Th2 effector-like function
    • Rose S., Lichtenheld M., Foote M.R., Adkins B. Murine neonatal CD4+ cells are poised for rapid Th2 effector-like function. J. Immunol. 2007, 178:2667-2678.
    • (2007) J. Immunol. , vol.178 , pp. 2667-2678
    • Rose, S.1    Lichtenheld, M.2    Foote, M.R.3    Adkins, B.4
  • 23
    • 34250773899 scopus 로고    scopus 로고
    • Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma
    • Schoenborn J.R., Dorschner M.O., Sekimata M., Santer D.M., Shnyreva M., Fitzpatrick D.R., et al. Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma. Nat. Immunol. 2007, 8:732-742.
    • (2007) Nat. Immunol. , vol.8 , pp. 732-742
    • Schoenborn, J.R.1    Dorschner, M.O.2    Sekimata, M.3    Santer, D.M.4    Shnyreva, M.5    Fitzpatrick, D.R.6
  • 24
    • 33847005427 scopus 로고    scopus 로고
    • The human IL-13 locus in neonatal CD4+ T cells is refractory to the acquisition of a repressive chromatin architecture
    • Webster R.B., Rodriguez Y., Klimecki W.T., Vercelli D. The human IL-13 locus in neonatal CD4+ T cells is refractory to the acquisition of a repressive chromatin architecture. J. Biol. Chem. 2007, 282:700-709.
    • (2007) J. Biol. Chem. , vol.282 , pp. 700-709
    • Webster, R.B.1    Rodriguez, Y.2    Klimecki, W.T.3    Vercelli, D.4
  • 25
    • 84864152547 scopus 로고    scopus 로고
    • Genome-scale profiling reveals a subset of genes regulated by DNA methylation that program somatic T-cell phenotypes in humans
    • Martino D., Maksimovic J., Joo J.H., Prescott S.L., Saffery R. Genome-scale profiling reveals a subset of genes regulated by DNA methylation that program somatic T-cell phenotypes in humans. Genes Immun. 2012, 13:388-398.
    • (2012) Genes Immun. , vol.13 , pp. 388-398
    • Martino, D.1    Maksimovic, J.2    Joo, J.H.3    Prescott, S.L.4    Saffery, R.5
  • 26
    • 80052555415 scopus 로고    scopus 로고
    • Evidence for age-related and individual-specific changes in DNA methylation profile of mononuclear cells during early immune development in humans
    • Martino D.J., Tulic M.K., Gordon L., Hodder M., Richman T.R., Metcalfe J., et al. Evidence for age-related and individual-specific changes in DNA methylation profile of mononuclear cells during early immune development in humans. Epigenetics 2011, 6:1085-1094.
    • (2011) Epigenetics , vol.6 , pp. 1085-1094
    • Martino, D.J.1    Tulic, M.K.2    Gordon, L.3    Hodder, M.4    Richman, T.R.5    Metcalfe, J.6
  • 27
    • 0037087421 scopus 로고    scopus 로고
    • Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO- T cells
    • White G.P., Watt P.M., Holt B.J., Holt P.G. Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO- T cells. J. Immunol. 2002, 168:2820-2827.
    • (2002) J. Immunol. , vol.168 , pp. 2820-2827
    • White, G.P.1    Watt, P.M.2    Holt, B.J.3    Holt, P.G.4
  • 28
    • 84870767737 scopus 로고    scopus 로고
    • Interindividual variability and co-regulation of DNA methylation differ among blood cell populations
    • Jacoby M., Gohrbandt S., Clausse V., Brons N.H., Muller C.P. Interindividual variability and co-regulation of DNA methylation differ among blood cell populations. Epigenetics 2012, 7:1421-1434.
    • (2012) Epigenetics , vol.7 , pp. 1421-1434
    • Jacoby, M.1    Gohrbandt, S.2    Clausse, V.3    Brons, N.H.4    Muller, C.P.5
  • 29
    • 0029940394 scopus 로고    scopus 로고
    • Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes
    • Luo C., Burgeon E., Carew J.A., McCaffrey P.G., Badalian T.M., Lane W.S., et al. Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes. Mol. Cell. Biol. 1996, 16:3955-3966.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 3955-3966
    • Luo, C.1    Burgeon, E.2    Carew, J.A.3    McCaffrey, P.G.4    Badalian, T.M.5    Lane, W.S.6
  • 30
    • 0032980432 scopus 로고    scopus 로고
    • Requirement for transcription factor NFAT in interleukin-2 expression
    • Chow C.W., Rincón M., Davis R.J. Requirement for transcription factor NFAT in interleukin-2 expression. Mol. Cell. Biol. 1999, 19:2300-2307.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2300-2307
    • Chow, C.W.1    Rincón, M.2    Davis, R.J.3
  • 31
    • 69249208597 scopus 로고    scopus 로고
    • MicroRNA 184 regulates expression of NFAT1 in umbilical cord blood CD4+ T cells
    • Weitzel R.P., Lesniewski M.L., Haviernik P., Kadereit S., Leahy P., Greco N.J., et al. microRNA 184 regulates expression of NFAT1 in umbilical cord blood CD4+ T cells. Blood 2009, 113:6648-6657.
    • (2009) Blood , vol.113 , pp. 6648-6657
    • Weitzel, R.P.1    Lesniewski, M.L.2    Haviernik, P.3    Kadereit, S.4    Leahy, P.5    Greco, N.J.6
  • 33
    • 79251592866 scopus 로고    scopus 로고
    • Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling
    • Nahid M.A., Satoh M., Chan E.K. Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling. J. Immunol. 2011, 186:1723-1734.
    • (2011) J. Immunol. , vol.186 , pp. 1723-1734
    • Nahid, M.A.1    Satoh, M.2    Chan, E.K.3
  • 34
    • 84891493875 scopus 로고    scopus 로고
    • Neonatal immunology: responses to pathogenic microorganisms and epigenetics reveal an immunodiverse developmental state
    • Adkins B. Neonatal immunology: responses to pathogenic microorganisms and epigenetics reveal an immunodiverse developmental state. Immunol. Res. 2013, 57:246-257.
    • (2013) Immunol. Res. , vol.57 , pp. 246-257
    • Adkins, B.1
  • 35
    • 0025281308 scopus 로고
    • Basis and implications of selectively diminished cytokine production in neonatal susceptibility to infection
    • Wilson C.B., Lewis D.B. Basis and implications of selectively diminished cytokine production in neonatal susceptibility to infection. Rev. Infect. Dis. 1990, 12:S410-S420.
    • (1990) Rev. Infect. Dis. , vol.12 , pp. S410-S420
    • Wilson, C.B.1    Lewis, D.B.2
  • 36
    • 0022512243 scopus 로고
    • Decreased production of interferon-gamma by human neonatal cells. Intrinsic and regulatory deficiencies
    • Wilson C.B., Westall J., Johnston L., Lewis D.B., Dower S.K., Alpert A.R. Decreased production of interferon-gamma by human neonatal cells. Intrinsic and regulatory deficiencies. J. Clin. Invest. 1986, 77:860-867.
    • (1986) J. Clin. Invest. , vol.77 , pp. 860-867
    • Wilson, C.B.1    Westall, J.2    Johnston, L.3    Lewis, D.B.4    Dower, S.K.5    Alpert, A.R.6
  • 37
    • 0028104891 scopus 로고
    • Candidacidal mechanisms in the human neonate. Impaired IFN-gamma activation of macrophages in newborn infants
    • Maródi L., Káposzta R., Campbell D.E., Polin R.A., Csongor J., Johnston R.B. Candidacidal mechanisms in the human neonate. Impaired IFN-gamma activation of macrophages in newborn infants. J. Immunol. 1994, 153:5643-5649.
    • (1994) J. Immunol. , vol.153 , pp. 5643-5649
    • Maródi, L.1    Káposzta, R.2    Campbell, D.E.3    Polin, R.A.4    Csongor, J.5    Johnston, R.B.6
  • 38
    • 34247588114 scopus 로고    scopus 로고
    • Innate immunity of the newborn: basic mechanisms and clinical correlates
    • Levy O. Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat. Rev. Immunol. 2007, 7:379-390.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 379-390
    • Levy, O.1
  • 39
    • 32044472547 scopus 로고    scopus 로고
    • Innate cellular immune responses in newborns
    • Maródi L. Innate cellular immune responses in newborns. Clin. Immunol. 2006, 118:137-144.
    • (2006) Clin. Immunol. , vol.118 , pp. 137-144
    • Maródi, L.1
  • 40
    • 70349777300 scopus 로고    scopus 로고
    • Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life
    • Belderbos M.E., van Bleek G.M., Levy O., Blanken M.O., Houben M.L., Schuijff L., et al. Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life. Clin. Immunol. 2009, 133:228-237.
    • (2009) Clin. Immunol. , vol.133 , pp. 228-237
    • Belderbos, M.E.1    van Bleek, G.M.2    Levy, O.3    Blanken, M.O.4    Houben, M.L.5    Schuijff, L.6
  • 41
    • 84913556128 scopus 로고    scopus 로고
    • Targeting regulatory T cells to improve vaccine immunogenicity in early life
    • Ndure J., Flanagan K.L. Targeting regulatory T cells to improve vaccine immunogenicity in early life. Front. Microbiol. 2014, 5:477.
    • (2014) Front. Microbiol. , vol.5 , pp. 477
    • Ndure, J.1    Flanagan, K.L.2
  • 42
    • 84885983093 scopus 로고    scopus 로고
    • TLR2-induced IL-10 production impairs neutrophil recruitment to infected tissues during neonatal bacterial sepsis
    • Andrade E.B., Alves J., Madureira P., Oliveira L., Ribeiro A., Cordeiro-da-Silva A., et al. TLR2-induced IL-10 production impairs neutrophil recruitment to infected tissues during neonatal bacterial sepsis. J. Immunol. 2013, 191:4759-4768.
    • (2013) J. Immunol. , vol.191 , pp. 4759-4768
    • Andrade, E.B.1    Alves, J.2    Madureira, P.3    Oliveira, L.4    Ribeiro, A.5    Cordeiro-da-Silva, A.6
  • 43
    • 0029036806 scopus 로고
    • Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones
    • Piccinni M.P., Giudizi M.G., Biagiotti R., Beloni L., Giannarini L., Sampognaro S., et al. Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones. J. Immunol. 1995, 155:128-133.
    • (1995) J. Immunol. , vol.155 , pp. 128-133
    • Piccinni, M.P.1    Giudizi, M.G.2    Biagiotti, R.3    Beloni, L.4    Giannarini, L.5    Sampognaro, S.6
  • 44
    • 0028931816 scopus 로고
    • Differential modulation of T helper type 1 (Th1) and T helper type 2 (Th2) cytokine secretion by prostaglandin E2 critically depends on interleukin 2
    • Hilkens C.M., Vermeulen H., Neerven R., Snijdewint F.G., Wierenga E.A., Kapsenberg M.L. Differential modulation of T helper type 1 (Th1) and T helper type 2 (Th2) cytokine secretion by prostaglandin E2 critically depends on interleukin 2. Eur. J. Immunol. 1995, 25:59-63.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 59-63
    • Hilkens, C.M.1    Vermeulen, H.2    Neerven, R.3    Snijdewint, F.G.4    Wierenga, E.A.5    Kapsenberg, M.L.6
  • 45
    • 33746609802 scopus 로고    scopus 로고
    • Elevated circulating IL-12 and TNF-alpha, and unaltered IL-6 in first-trimester pregnancies complicated by threatened abortion with an adverse outcome
    • Vitoratos N., Papadias C., Economou E., Makrakis E., Panoulis C., Creatsas G. Elevated circulating IL-12 and TNF-alpha, and unaltered IL-6 in first-trimester pregnancies complicated by threatened abortion with an adverse outcome. Mediators Inflamm. 2006, 2006:30485.
    • (2006) Mediators Inflamm. , vol.2006 , pp. 30485
    • Vitoratos, N.1    Papadias, C.2    Economou, E.3    Makrakis, E.4    Panoulis, C.5    Creatsas, G.6
  • 46
    • 0027207375 scopus 로고
    • Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH 2 phenomenon?
    • Wegmann T.G., Lin H., Guilbert L., Mosmann T.R. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH 2 phenomenon?. Immunol. Today 1993, 14:353-356.
    • (1993) Immunol. Today , vol.14 , pp. 353-356
    • Wegmann, T.G.1    Lin, H.2    Guilbert, L.3    Mosmann, T.R.4
  • 47
    • 2642566198 scopus 로고    scopus 로고
    • Defective macrophage function in neonates and its impact on unresponsiveness of neonates to polysaccharide antigens
    • Chelvarajan R.L., Collins S.M., Doubinskaia I.E., Goes S., Willigen J.V., Flanagan D., et al. Defective macrophage function in neonates and its impact on unresponsiveness of neonates to polysaccharide antigens. J. Leukoc. Biol. 2004, 75:982-994.
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 982-994
    • Chelvarajan, R.L.1    Collins, S.M.2    Doubinskaia, I.E.3    Goes, S.4    Willigen, J.V.5    Flanagan, D.6
  • 48
    • 0042671489 scopus 로고    scopus 로고
    • Defective production of IL-18 and IL-12 by cord blood mononuclear cells influences the T helper-1 interferon gamma response to group B Streptococci
    • Pine L.T., Joyner J.L., Augustine N.H., Kwak S.D., Hill H.R. Defective production of IL-18 and IL-12 by cord blood mononuclear cells influences the T helper-1 interferon gamma response to group B Streptococci. Pediatr. Res. 2003, 54:276-281.
    • (2003) Pediatr. Res. , vol.54 , pp. 276-281
    • Pine, L.T.1    Joyner, J.L.2    Augustine, N.H.3    Kwak, S.D.4    Hill, H.R.5
  • 49
    • 0035012068 scopus 로고    scopus 로고
    • Neonatal bacillus Calmette-Guérin vaccination induces adult-like IFN-gamma production by CD4+ T lymphocytes
    • Vekemans J., Amedei A., Ota M.O., D'Elios M.M., Goetghebuer T., Ismaili J., et al. Neonatal bacillus Calmette-Guérin vaccination induces adult-like IFN-gamma production by CD4+ T lymphocytes. Eur. J. Immunol. 2001, 31:1531-1535.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1531-1535
    • Vekemans, J.1    Amedei, A.2    Ota, M.O.3    D'Elios, M.M.4    Goetghebuer, T.5    Ismaili, J.6
  • 50
    • 33845327856 scopus 로고    scopus 로고
    • Modulation of the infant immune responses by the first pertussis vaccine administrations
    • Mascart F., Hainaut M., Peltier A., Verscheure V., Levy J., Locht C. Modulation of the infant immune responses by the first pertussis vaccine administrations. Vaccine 2007, 25:391-398.
    • (2007) Vaccine , vol.25 , pp. 391-398
    • Mascart, F.1    Hainaut, M.2    Peltier, A.3    Verscheure, V.4    Levy, J.5    Locht, C.6
  • 51
    • 77956397972 scopus 로고    scopus 로고
    • Acquisition of adult-Like TLR4 and TLR9 Responses during the first year of life
    • Nguyen M., Leuridan E., Zhang T., Wit D., Willems F., Damme P.V., et al. Acquisition of adult-Like TLR4 and TLR9 Responses during the first year of life. PLoS One 2010, 5:e10407.
    • (2010) PLoS One , vol.5 , pp. e10407
    • Nguyen, M.1    Leuridan, E.2    Zhang, T.3    Wit, D.4    Willems, F.5    Damme, P.V.6
  • 53
    • 78649764135 scopus 로고    scopus 로고
    • Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells
    • Corbett N.P., Blimkie D., Ho K.C., Cai B., Sutherland D.P., Kallos A., et al. Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells. PLoS One 2010, 5:e15041.
    • (2010) PLoS One , vol.5 , pp. e15041
    • Corbett, N.P.1    Blimkie, D.2    Ho, K.C.3    Cai, B.4    Sutherland, D.P.5    Kallos, A.6
  • 54
    • 78649565977 scopus 로고    scopus 로고
    • Profound lack of interleukin (IL)-12/IL-23p40 in neonates born early in gestation is associated with an increased risk of sepsis
    • Lavoie P.M., Huang Q., Jolette E., Whalen M., Nuyt A.M., Audibert F., et al. Profound lack of interleukin (IL)-12/IL-23p40 in neonates born early in gestation is associated with an increased risk of sepsis. J. Infect. Dis. 2010, 202:1754-1763.
    • (2010) J. Infect. Dis. , vol.202 , pp. 1754-1763
    • Lavoie, P.M.1    Huang, Q.2    Jolette, E.3    Whalen, M.4    Nuyt, A.M.5    Audibert, F.6
  • 55
    • 84869228450 scopus 로고    scopus 로고
    • Innate immune function by Toll-like receptors: distinct responses in newborns and the elderly
    • Kollmann T.R., Levy O., Montgomery R.R., Goriely S. Innate immune function by Toll-like receptors: distinct responses in newborns and the elderly. Immunity 2012, 37:771-783.
    • (2012) Immunity , vol.37 , pp. 771-783
    • Kollmann, T.R.1    Levy, O.2    Montgomery, R.R.3    Goriely, S.4
  • 56
    • 0032956143 scopus 로고    scopus 로고
    • Developmental microbial ecology of the neonatal gastrointestinal tract
    • Mackie R.I., Sghir A., Gaskins R.H. Developmental microbial ecology of the neonatal gastrointestinal tract. Am. J. Clin. Nutr. 1999, 69:1035-1045.
    • (1999) Am. J. Clin. Nutr. , vol.69 , pp. 1035-1045
    • Mackie, R.I.1    Sghir, A.2    Gaskins, R.H.3
  • 57
    • 78650507714 scopus 로고    scopus 로고
    • Mucosal immune system in neonatal period and early infancy
    • Ogra P. Mucosal immune system in neonatal period and early infancy. Ped. Health 2010, 4:637-647.
    • (2010) Ped. Health , vol.4 , pp. 637-647
    • Ogra, P.1
  • 59
    • 66449088641 scopus 로고    scopus 로고
    • Pathogen recognition and inflammatory signaling in innate immune defenses
    • Mogensen T.H. Pathogen recognition and inflammatory signaling in innate immune defenses. Clin. Microbiol. Rev. 2009, 22:240-273.
    • (2009) Clin. Microbiol. Rev. , vol.22 , pp. 240-273
    • Mogensen, T.H.1
  • 60
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S., Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 2004, 4:499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 62
    • 84886736662 scopus 로고    scopus 로고
    • Cord blood monocytes, neutrophils and lymphocytes from preterm and full-term neonates show multiple aberrations in signalling profiles measured using phospho-specific whole-blood flow cytometry
    • Nupponen I., Kuuliala A., Siitonen S., Repo H., Kuuliala K. Cord blood monocytes, neutrophils and lymphocytes from preterm and full-term neonates show multiple aberrations in signalling profiles measured using phospho-specific whole-blood flow cytometry. Scand. J. Immunol. 2013, 78:426-438.
    • (2013) Scand. J. Immunol. , vol.78 , pp. 426-438
    • Nupponen, I.1    Kuuliala, A.2    Siitonen, S.3    Repo, H.4    Kuuliala, K.5
  • 63
    • 0018895768 scopus 로고
    • Exhaustion of mature marrow neutrophils in neonates with sepsis
    • Christensen R.D., Rothstein G. Exhaustion of mature marrow neutrophils in neonates with sepsis. Eur. J. Pediatr. 1980, 96:316-318.
    • (1980) Eur. J. Pediatr. , vol.96 , pp. 316-318
    • Christensen, R.D.1    Rothstein, G.2
  • 64
    • 0018642289 scopus 로고
    • Phagocyte function in the neonate: selected aspects
    • Miller M.E. Phagocyte function in the neonate: selected aspects. Pediatrics 1979, 64:709-712.
    • (1979) Pediatrics , vol.64 , pp. 709-712
    • Miller, M.E.1
  • 65
    • 0031784698 scopus 로고    scopus 로고
    • Passive deformability of mature immature, and active neutrophils in healthy and septicemic neonates
    • Linderkamp O., Ruef P., Brenner B., Gulbins E., Lang F. Passive deformability of mature immature, and active neutrophils in healthy and septicemic neonates. Pediatr. Res. 1998, 44:946-950.
    • (1998) Pediatr. Res. , vol.44 , pp. 946-950
    • Linderkamp, O.1    Ruef, P.2    Brenner, B.3    Gulbins, E.4    Lang, F.5
  • 66
    • 84890497927 scopus 로고    scopus 로고
    • Neutropenia in the newborn
    • Maheshwari A. Neutropenia in the newborn. Curr. Opin. Hematol. 2014, 21:43-49.
    • (2014) Curr. Opin. Hematol. , vol.21 , pp. 43-49
    • Maheshwari, A.1
  • 67
    • 0025869795 scopus 로고
    • Diminished lectin epidermal growth factor, complement binding domain-cell adhesion molecule-1 on neonatal neutrophils underlies their impaired CD18-independent adhesion to endothelial cells in vitro
    • Anderson D.C., Abbassi O., Kishimoto T.K., Koenig J.M., McIntire L.V., Smith C.W. Diminished lectin epidermal growth factor, complement binding domain-cell adhesion molecule-1 on neonatal neutrophils underlies their impaired CD18-independent adhesion to endothelial cells in vitro. J. Immunol. 1991, 146:3372-3379.
    • (1991) J. Immunol. , vol.146 , pp. 3372-3379
    • Anderson, D.C.1    Abbassi, O.2    Kishimoto, T.K.3    Koenig, J.M.4    McIntire, L.V.5    Smith, C.W.6
  • 68
    • 0021227906 scopus 로고
    • Chemotactic peptide modulation of actin assembly and locomotion in neutrophils
    • Howard T.H., Meyer W.H. Chemotactic peptide modulation of actin assembly and locomotion in neutrophils. J. Cell Biol. 1984, 98:1265-1271.
    • (1984) J. Cell Biol. , vol.98 , pp. 1265-1271
    • Howard, T.H.1    Meyer, W.H.2
  • 69
    • 0033805393 scopus 로고    scopus 로고
    • Neutrophil chemotaxis and random migration in preterm and term infants with sepsis
    • Türkmen M., Satar M., Atici A. Neutrophil chemotaxis and random migration in preterm and term infants with sepsis. Am. J. Perinatol. 2000, 17:107-112.
    • (2000) Am. J. Perinatol. , vol.17 , pp. 107-112
    • Türkmen, M.1    Satar, M.2    Atici, A.3
  • 70
    • 84904011922 scopus 로고    scopus 로고
    • Quantitative proteomics reveals differential biological processes in healthy neonatal cord neutrophils and adult neutrophils
    • Zhu J., Zhang H., Guo T., Li W., Li H., Zhu Y., et al. Quantitative proteomics reveals differential biological processes in healthy neonatal cord neutrophils and adult neutrophils. Proteomics 2014, 14:1688-1697.
    • (2014) Proteomics , vol.14 , pp. 1688-1697
    • Zhu, J.1    Zhang, H.2    Guo, T.3    Li, W.4    Li, H.5    Zhu, Y.6
  • 71
    • 84929500766 scopus 로고    scopus 로고
    • Neutrophil chemotaxis in cord blood of term and preterm neonates is reduced in preterm neonates and influenced by the mode of delivery and anaesthesia
    • Birle A., Nebe C.T., Hill S., Hartmann K., Poeschl J., Koch L. Neutrophil chemotaxis in cord blood of term and preterm neonates is reduced in preterm neonates and influenced by the mode of delivery and anaesthesia. PLoS One 2015, 10:e0120341.
    • (2015) PLoS One , vol.10 , pp. e0120341
    • Birle, A.1    Nebe, C.T.2    Hill, S.3    Hartmann, K.4    Poeschl, J.5    Koch, L.6
  • 74
    • 0032714626 scopus 로고    scopus 로고
    • Impaired innate immunity in the newborn: newborn neutrophils are deficient in bactericidal/permeability-increasing protein
    • Levy O., Martin S., Eichenwald E., Ganz T., Valore E., Carroll S.F., et al. Impaired innate immunity in the newborn: newborn neutrophils are deficient in bactericidal/permeability-increasing protein. Pediatrics 1999, 104:1327-1333.
    • (1999) Pediatrics , vol.104 , pp. 1327-1333
    • Levy, O.1    Martin, S.2    Eichenwald, E.3    Ganz, T.4    Valore, E.5    Carroll, S.F.6
  • 75
    • 0030830042 scopus 로고    scopus 로고
    • Impact of prematurity, stress and sepsis on the neutrophil respiratory burst activity of neonates
    • Drossou V., Kanakoudi F., Tzimouli V., Sarafidis K., Taparkou A., Bougiouklis D., et al. Impact of prematurity, stress and sepsis on the neutrophil respiratory burst activity of neonates. Biol. Neonate 1997, 72:201-209.
    • (1997) Biol. Neonate , vol.72 , pp. 201-209
    • Drossou, V.1    Kanakoudi, F.2    Tzimouli, V.3    Sarafidis, K.4    Taparkou, A.5    Bougiouklis, D.6
  • 76
    • 80052182726 scopus 로고    scopus 로고
    • Human neonatal neutrophils are resistant to apoptosis with lower caspase-3 activity
    • Song C., Wang C., Huang L. Human neonatal neutrophils are resistant to apoptosis with lower caspase-3 activity. Tohoku J. Exp. Med. 2011, 225:59-63.
    • (2011) Tohoku J. Exp. Med. , vol.225 , pp. 59-63
    • Song, C.1    Wang, C.2    Huang, L.3
  • 77
    • 67650638848 scopus 로고    scopus 로고
    • Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates
    • Yost C.C., Cody M.J., Harris E.S., Thornton N.L., McInturff A.M., Martinez M.L., et al. Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates. Blood 2009, 113:6419-6427.
    • (2009) Blood , vol.113 , pp. 6419-6427
    • Yost, C.C.1    Cody, M.J.2    Harris, E.S.3    Thornton, N.L.4    McInturff, A.M.5    Martinez, M.L.6
  • 78
    • 74049101676 scopus 로고    scopus 로고
    • Delayed but functional neutrophil extracellular trap formation in neonates
    • Marcos V., Nussbaum C., Vitkov L., Hector A., Wiedenbauer E.M., Roos D., et al. Delayed but functional neutrophil extracellular trap formation in neonates. Blood 2009, 114:4908-4911.
    • (2009) Blood , vol.114 , pp. 4908-4911
    • Marcos, V.1    Nussbaum, C.2    Vitkov, L.3    Hector, A.4    Wiedenbauer, E.M.5    Roos, D.6
  • 80
    • 35148826063 scopus 로고    scopus 로고
    • Human newborn polymorphonuclear neutrophils exhibit decreased levels of MyD88 and attenuated p38 phosphorylation in response to lipopolysaccharide
    • Al-Hertani W., Yan S.R., Byers D.M., Bortolussi R. Human newborn polymorphonuclear neutrophils exhibit decreased levels of MyD88 and attenuated p38 phosphorylation in response to lipopolysaccharide. Clin. Invest. Med. 2007, 30:E44-53.
    • (2007) Clin. Invest. Med. , vol.30 , pp. E44-53
    • Al-Hertani, W.1    Yan, S.R.2    Byers, D.M.3    Bortolussi, R.4
  • 82
    • 33746214770 scopus 로고    scopus 로고
    • The adenosine system selectively inhibits TLR-mediated TNF-alpha production in the human newborn
    • Levy O., Coughlin M., Cronstein B.N., Roy R.M., Desai A., Wessels M.R. The adenosine system selectively inhibits TLR-mediated TNF-alpha production in the human newborn. J. Immunol. 2006, 177:1956-1966.
    • (2006) J. Immunol. , vol.177 , pp. 1956-1966
    • Levy, O.1    Coughlin, M.2    Cronstein, B.N.3    Roy, R.M.4    Desai, A.5    Wessels, M.R.6
  • 83
    • 84908022128 scopus 로고    scopus 로고
    • Intramuscular administration of a synthetic CpG-oligodeoxynucleotide modulates functional responses of neutrophils of neonatal foals
    • Cohen N.D., Bourquin J.R., Bordin A.I., Kuskie K.R., Brake C.N., Weaver K.B., et al. Intramuscular administration of a synthetic CpG-oligodeoxynucleotide modulates functional responses of neutrophils of neonatal foals. PLoS One 2014, 9:e109865.
    • (2014) PLoS One , vol.9 , pp. e109865
    • Cohen, N.D.1    Bourquin, J.R.2    Bordin, A.I.3    Kuskie, K.R.4    Brake, C.N.5    Weaver, K.B.6
  • 84
    • 84856902335 scopus 로고    scopus 로고
    • Toll-like receptor 1/2 stimulation induces elevated interleukin-8 secretion in polymorphonuclear leukocytes isolated from preterm and term newborn infants
    • Thornton N.L., Cody M.J., Yost C.C. Toll-like receptor 1/2 stimulation induces elevated interleukin-8 secretion in polymorphonuclear leukocytes isolated from preterm and term newborn infants. Neonatology 2012, 101:140-146.
    • (2012) Neonatology , vol.101 , pp. 140-146
    • Thornton, N.L.1    Cody, M.J.2    Yost, C.C.3
  • 85
    • 84883643725 scopus 로고    scopus 로고
    • Neutrophilic myeloid-derived suppressor cells in cord blood modulate innate and adaptive immune responses
    • Rieber N., Gille C., Köstlin N., Schäfer I., Spring B., Ost M., et al. Neutrophilic myeloid-derived suppressor cells in cord blood modulate innate and adaptive immune responses. Clin. Exp. Immunol. 2013, 174:45-52.
    • (2013) Clin. Exp. Immunol. , vol.174 , pp. 45-52
    • Rieber, N.1    Gille, C.2    Köstlin, N.3    Schäfer, I.4    Spring, B.5    Ost, M.6
  • 86
    • 84941097059 scopus 로고    scopus 로고
    • Diminished HLA-DR expression on monocyte and dendritic cell subsets indicating impairment of cellular immunity in pre-term neonates: a prospective observational analysis
    • Schefold J.C., Porz L., Uebe B., Poehlmann H., von Haehling S., Jung A., et al. Diminished HLA-DR expression on monocyte and dendritic cell subsets indicating impairment of cellular immunity in pre-term neonates: a prospective observational analysis. J. Perinat. Med. 2015, 43:609-618.
    • (2015) J. Perinat. Med. , vol.43 , pp. 609-618
    • Schefold, J.C.1    Porz, L.2    Uebe, B.3    Poehlmann, H.4    von Haehling, S.5    Jung, A.6
  • 87
    • 77955176728 scopus 로고    scopus 로고
    • Reference ranges for blood concentrations of eosinophils and monocytes during the neonatal period defined from over 63 000 records in a multihospital health-care system
    • Christensen R.D., Jensen J., Maheshwari A., Henry E. Reference ranges for blood concentrations of eosinophils and monocytes during the neonatal period defined from over 63 000 records in a multihospital health-care system. J. Perinatol. 2010, 30:540-545.
    • (2010) J. Perinatol. , vol.30 , pp. 540-545
    • Christensen, R.D.1    Jensen, J.2    Maheshwari, A.3    Henry, E.4
  • 88
    • 84946064371 scopus 로고    scopus 로고
    • Attenuated innate immune defenses in very premature neonates during the neonatal period
    • Marchant E.A., Kan B., Sharma A.A., van Zanten A., Kollmann T.R., Brant R., et al. Attenuated innate immune defenses in very premature neonates during the neonatal period. Pediatr. Res. 2015, 78:492-497.
    • (2015) Pediatr. Res. , vol.78 , pp. 492-497
    • Marchant, E.A.1    Kan, B.2    Sharma, A.A.3    van Zanten, A.4    Kollmann, T.R.5    Brant, R.6
  • 89
    • 0019169911 scopus 로고
    • Chemotactic and random movement of human newborn monocytes
    • Marodi L., Scorba S., Nagy B. Chemotactic and random movement of human newborn monocytes. Eur. J. Pediatr. 1980, 135:73-75.
    • (1980) Eur. J. Pediatr. , vol.135 , pp. 73-75
    • Marodi, L.1    Scorba, S.2    Nagy, B.3
  • 90
    • 78049268621 scopus 로고    scopus 로고
    • Monocytes in neonatal immunity
    • Mahdi M., Maródi L. Monocytes in neonatal immunity. NeoReviews 2010, 11:e558-e565.
    • (2010) NeoReviews , vol.11 , pp. e558-e565
    • Mahdi, M.1    Maródi, L.2
  • 91
    • 0027315505 scopus 로고
    • Diversity in regulation of adhesion molecules (Mac-1 and l-selectin) in monocytes and neutrophils from neonates and adults
    • Török C., Lundahl J., Hed J., Lagercrantz H. Diversity in regulation of adhesion molecules (Mac-1 and l-selectin) in monocytes and neutrophils from neonates and adults. Arch. Dis. Child. 1993, 68:561-565.
    • (1993) Arch. Dis. Child. , vol.68 , pp. 561-565
    • Török, C.1    Lundahl, J.2    Hed, J.3    Lagercrantz, H.4
  • 92
    • 84887464732 scopus 로고    scopus 로고
    • Phagocytosis of neonatal pathogens by peripheral blood neutrophils and monocytes from newborn preterm and term infants
    • Prosser A., Hibbert J., Strunk T., Kok C.H., Simmer K., Richmond P., et al. Phagocytosis of neonatal pathogens by peripheral blood neutrophils and monocytes from newborn preterm and term infants. Pediatr. Res. 2013, 74:503-510.
    • (2013) Pediatr. Res. , vol.74 , pp. 503-510
    • Prosser, A.1    Hibbert, J.2    Strunk, T.3    Kok, C.H.4    Simmer, K.5    Richmond, P.6
  • 94
    • 84900535373 scopus 로고    scopus 로고
    • Differential induction of cytokines by human neonatal, adult, and elderly monocyte/macrophages infected with dengue virus
    • Valero N., Mosquera J., Levy A., Añez G., Marcucci R., Alvarez-Mon M. Differential induction of cytokines by human neonatal, adult, and elderly monocyte/macrophages infected with dengue virus. Viral Immunol. 2014, 27:151-159.
    • (2014) Viral Immunol. , vol.27 , pp. 151-159
    • Valero, N.1    Mosquera, J.2    Levy, A.3    Añez, G.4    Marcucci, R.5    Alvarez-Mon, M.6
  • 95
    • 84921064072 scopus 로고    scopus 로고
    • Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes
    • Sharma A.A., Jen R., Kan B., Sharma A., Marchant E., Tang A., et al. Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes. Eur. J. Immunol. 2015, 45:238-249.
    • (2015) Eur. J. Immunol. , vol.45 , pp. 238-249
    • Sharma, A.A.1    Jen, R.2    Kan, B.3    Sharma, A.4    Marchant, E.5    Tang, A.6
  • 96
    • 84925517597 scopus 로고    scopus 로고
    • An impaired inflammatory cytokine response to gram-negative LPS in human neonates is associated with the defective TLR-mediated signaling pathway
    • Li Y.P., Yu S.L., Huang Z.J., Huang J., Pan J., Feng X., et al. An impaired inflammatory cytokine response to gram-negative LPS in human neonates is associated with the defective TLR-mediated signaling pathway. J. Clin. Immunol. 2015, 35:218-226.
    • (2015) J. Clin. Immunol. , vol.35 , pp. 218-226
    • Li, Y.P.1    Yu, S.L.2    Huang, Z.J.3    Huang, J.4    Pan, J.5    Feng, X.6
  • 97
    • 1342323844 scopus 로고    scopus 로고
    • Role of MyD88 in diminished tumor necrosis factor alpha production by newborn mononuclear cells in response to lipopolysaccharide
    • Yan S.R., Qing G., Byers D.M., Stadnyk A.W., Al-Hertani W., Bortolussi R. Role of MyD88 in diminished tumor necrosis factor alpha production by newborn mononuclear cells in response to lipopolysaccharide. Infect. Immun. 2004, 72:1223-1229.
    • (2004) Infect. Immun. , vol.72 , pp. 1223-1229
    • Yan, S.R.1    Qing, G.2    Byers, D.M.3    Stadnyk, A.W.4    Al-Hertani, W.5    Bortolussi, R.6
  • 98
    • 4644307506 scopus 로고    scopus 로고
    • Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-alpha induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848
    • Levy O., Zarember K.A., Roy R.M., Cywes C., Godowski P.J., Wessels M.R. Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-alpha induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848. J. Immunol. 2004, 173:4627-4634.
    • (2004) J. Immunol. , vol.173 , pp. 4627-4634
    • Levy, O.1    Zarember, K.A.2    Roy, R.M.3    Cywes, C.4    Godowski, P.J.5    Wessels, M.R.6
  • 99
    • 84862900303 scopus 로고    scopus 로고
    • Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways
    • (e9)
    • Philbin V.J., Dowling D.J., Gallington L.C., Cortés G., Tan Z., Suter E.E., et al. Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways. J. Allergy Clin. Immunol. 2012, 130(2012):195-204. (e9).
    • (2012) J. Allergy Clin. Immunol. , vol.130 , Issue.2012 , pp. 195-204
    • Philbin, V.J.1    Dowling, D.J.2    Gallington, L.C.3    Cortés, G.4    Tan, Z.5    Suter, E.E.6
  • 100
    • 84863492212 scopus 로고    scopus 로고
    • MiRNA-125b regulates TNF-α production in CD14+ neonatal monocytes via post-transcriptional regulation
    • Huang H.C., Yu H.R., Huang L.T., Huang H.C., Chen R.F., Lin I.C., et al. miRNA-125b regulates TNF-α production in CD14+ neonatal monocytes via post-transcriptional regulation. J. Leukoc. Biol. 2012, 92:171-182.
    • (2012) J. Leukoc. Biol. , vol.92 , pp. 171-182
    • Huang, H.C.1    Yu, H.R.2    Huang, L.T.3    Huang, H.C.4    Chen, R.F.5    Lin, I.C.6
  • 101
    • 84904668417 scopus 로고    scopus 로고
    • Neonatal monocytes express antiapoptotic pattern of Bcl-2 proteins and show diminished apoptosis upon infection with Escherichia coli
    • Leiber A., Graf B., Spring B., Rudner J., Köstlin N., Orlikowsky T.W., et al. Neonatal monocytes express antiapoptotic pattern of Bcl-2 proteins and show diminished apoptosis upon infection with Escherichia coli. Pediatr. Res. 2014, 76:142-149.
    • (2014) Pediatr. Res. , vol.76 , pp. 142-149
    • Leiber, A.1    Graf, B.2    Spring, B.3    Rudner, J.4    Köstlin, N.5    Orlikowsky, T.W.6
  • 102
    • 84875683791 scopus 로고    scopus 로고
    • The CD95/CD95L pathway is involved in phagocytosis-induced cell death of monocytes and may account for sustained inflammation in neonates
    • Gille C., Dreschers S., Leiber A., Lepiorz F., Krusch M., Grosse-Opphoff J., et al. The CD95/CD95L pathway is involved in phagocytosis-induced cell death of monocytes and may account for sustained inflammation in neonates. Pediatr. Res. 2013, 73:402-408.
    • (2013) Pediatr. Res. , vol.73 , pp. 402-408
    • Gille, C.1    Dreschers, S.2    Leiber, A.3    Lepiorz, F.4    Krusch, M.5    Grosse-Opphoff, J.6
  • 103
    • 84940056692 scopus 로고    scopus 로고
    • Age-related gene expression differences in monocytes from human neonates, young adults, and older adults
    • Lissner M.M., Thomas B.J., Wee K., Tong A.J., Kollmann T.R., Smale S.T. Age-related gene expression differences in monocytes from human neonates, young adults, and older adults. PLoS One 2015, 10:e0132061.
    • (2015) PLoS One , vol.10 , pp. e0132061
    • Lissner, M.M.1    Thomas, B.J.2    Wee, K.3    Tong, A.J.4    Kollmann, T.R.5    Smale, S.T.6
  • 105
    • 0023802007 scopus 로고
    • Phagocytosis-associated functions in neonatal monocyte-derived macrophages
    • Speer C.P., Gahr M., Wieland M., Eber S. Phagocytosis-associated functions in neonatal monocyte-derived macrophages. Pediatr. Res. 1988, 24:213-216.
    • (1988) Pediatr. Res. , vol.24 , pp. 213-216
    • Speer, C.P.1    Gahr, M.2    Wieland, M.3    Eber, S.4
  • 106
    • 84877623748 scopus 로고    scopus 로고
    • Maturation of Toll-like receptor 1-4 responsiveness during early life
    • Liao S.L., Yeh K.W., Lai S.H., Lee W.I., Huang J.L. Maturation of Toll-like receptor 1-4 responsiveness during early life. Early Hum. Dev. 2013, 89:473-478.
    • (2013) Early Hum. Dev. , vol.89 , pp. 473-478
    • Liao, S.L.1    Yeh, K.W.2    Lai, S.H.3    Lee, W.I.4    Huang, J.L.5
  • 107
    • 84864802021 scopus 로고    scopus 로고
    • Alveolar macrophages in neonatal mice are inherently unresponsive to Pneumocystis murina infection
    • Kurkjian C., Hollifield M., Lines J.L., Rogosky A., Empey K.M., Qureshi M., et al. Alveolar macrophages in neonatal mice are inherently unresponsive to Pneumocystis murina infection. Infect. Immun. 2012, 80:2835-2846.
    • (2012) Infect. Immun. , vol.80 , pp. 2835-2846
    • Kurkjian, C.1    Hollifield, M.2    Lines, J.L.3    Rogosky, A.4    Empey, K.M.5    Qureshi, M.6
  • 108
    • 84879825719 scopus 로고    scopus 로고
    • Neonatal macrophages express elevated levels of interleukin-27 that oppose immune responses
    • Kraft J.D., Horzempa J., Davis C., Jung J.Y., Peña M.M., Robinson C.M. Neonatal macrophages express elevated levels of interleukin-27 that oppose immune responses. Immunology 2013, 139:484-493.
    • (2013) Immunology , vol.139 , pp. 484-493
    • Kraft, J.D.1    Horzempa, J.2    Davis, C.3    Jung, J.Y.4    Peña, M.M.5    Robinson, C.M.6
  • 109
    • 84935420202 scopus 로고    scopus 로고
    • Overexpression of Bovine FcRn in mice enhances T-dependent immune responses by amplifying T helper cell frequency and germinal center enlargement in the spleen
    • Schneider Z., Jani P.K.K., Szikora B., Végh A., Kövesdi D., Iliás A., et al. Overexpression of Bovine FcRn in mice enhances T-dependent immune responses by amplifying T helper cell frequency and germinal center enlargement in the spleen. Front. Immunol. 2015, 6:357.
    • (2015) Front. Immunol. , vol.6 , pp. 357
    • Schneider, Z.1    Jani, P.K.K.2    Szikora, B.3    Végh, A.4    Kövesdi, D.5    Iliás, A.6
  • 110
    • 79955024081 scopus 로고    scopus 로고
    • The neonatal FcR-mediated presentation of immune-complexed antigen is associated with endosomal and phagosomal pH and antigen stability in macrophages and dendritic cells
    • Liu X., Lu L., Yang Z., Palaniyandi S., Zeng R., Gao L.Y., et al. The neonatal FcR-mediated presentation of immune-complexed antigen is associated with endosomal and phagosomal pH and antigen stability in macrophages and dendritic cells. J. Immunol. 2011, 186:4674-4686.
    • (2011) J. Immunol. , vol.186 , pp. 4674-4686
    • Liu, X.1    Lu, L.2    Yang, Z.3    Palaniyandi, S.4    Zeng, R.5    Gao, L.Y.6
  • 111
    • 0035653055 scopus 로고    scopus 로고
    • Cytokine receptor signalling in neonatal macrophages: defective STAT-1 phosphorylation in response to stimulation with IFN-γ
    • Maródi L., Goda K., Palicz A., Szabó G. Cytokine receptor signalling in neonatal macrophages: defective STAT-1 phosphorylation in response to stimulation with IFN-γ. Clin. Exp. Immunol. 2001, 126:456-460.
    • (2001) Clin. Exp. Immunol. , vol.126 , pp. 456-460
    • Maródi, L.1    Goda, K.2    Palicz, A.3    Szabó, G.4
  • 112
    • 84863707107 scopus 로고    scopus 로고
    • Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection
    • Empey K.M., Orend J.G., Peebles R.S., Egaña L., Norris K.A., Oury T.D., et al. Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection. PLoS One 2012, 7:e40499.
    • (2012) PLoS One , vol.7 , pp. e40499
    • Empey, K.M.1    Orend, J.G.2    Peebles, R.S.3    Egaña, L.4    Norris, K.A.5    Oury, T.D.6
  • 113
    • 84907483941 scopus 로고    scopus 로고
    • Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
    • Saeed S., Quintin J., Kerstens H.H., Rao N.A., Aghajanirefah A., Matarese F., et al. Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity. Science 2014, 345:1251086.
    • (2014) Science , vol.345 , pp. 1251086
    • Saeed, S.1    Quintin, J.2    Kerstens, H.H.3    Rao, N.A.4    Aghajanirefah, A.5    Matarese, F.6
  • 114
    • 39349114159 scopus 로고    scopus 로고
    • Dendritic cell subsets and toll-like receptors
    • Hochrein H., O'Keeffe M. Dendritic cell subsets and toll-like receptors. Handb. Exp. Pharmacol. 2008, 183:153-179.
    • (2008) Handb. Exp. Pharmacol. , vol.183 , pp. 153-179
    • Hochrein, H.1    O'Keeffe, M.2
  • 116
    • 34250159927 scopus 로고    scopus 로고
    • Development of dendritic-cell lineages
    • Wu L., Liu Y.J. Development of dendritic-cell lineages. Immunity 2007, 26:741-750.
    • (2007) Immunity , vol.26 , pp. 741-750
    • Wu, L.1    Liu, Y.J.2
  • 117
    • 33744473294 scopus 로고    scopus 로고
    • Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes
    • Naik S.H., Metcalf D., van Nieuwenhuijze A., Wicks I., Wu L., O'Keeffe M., et al. Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes. Nat. Immunol. 2006, 7:663-671.
    • (2006) Nat. Immunol. , vol.7 , pp. 663-671
    • Naik, S.H.1    Metcalf, D.2    van Nieuwenhuijze, A.3    Wicks, I.4    Wu, L.5    O'Keeffe, M.6
  • 118
    • 0037625155 scopus 로고    scopus 로고
    • TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection
    • Serbina N.V., Salazar-Mather T.P., Biron C.A., Kuziel W.A., Pamer E.G. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 2003, 19:59-70.
    • (2003) Immunity , vol.19 , pp. 59-70
    • Serbina, N.V.1    Salazar-Mather, T.P.2    Biron, C.A.3    Kuziel, W.A.4    Pamer, E.G.5
  • 119
    • 0034942531 scopus 로고    scopus 로고
    • Identification of both myeloid CD11c+ and lymphoid CD11c- dendritic cell subsets in cord blood
    • Borràs F.E., Matthews N.C., Lowdell M.W., Navarrete C.V. Identification of both myeloid CD11c+ and lymphoid CD11c- dendritic cell subsets in cord blood. Br. J. Haematol. 2001, 113:925-931.
    • (2001) Br. J. Haematol. , vol.113 , pp. 925-931
    • Borràs, F.E.1    Matthews, N.C.2    Lowdell, M.W.3    Navarrete, C.V.4
  • 122
    • 33846455836 scopus 로고    scopus 로고
    • The functional immaturity of dendritic cells can be relevant to increased tolerance associated with cord blood transplantation
    • Encabo A., Solves P., Carbonell-Uberos F., Miñana M.D. The functional immaturity of dendritic cells can be relevant to increased tolerance associated with cord blood transplantation. Transfusion 2007, 47:272-279.
    • (2007) Transfusion , vol.47 , pp. 272-279
    • Encabo, A.1    Solves, P.2    Carbonell-Uberos, F.3    Miñana, M.D.4
  • 123
    • 0028067831 scopus 로고
    • Studies of human cord blood dendritic cells: evidence for functional immaturity
    • Hunt D.W., Huppertz H.I., Jiang H.J., Petty R.E. Studies of human cord blood dendritic cells: evidence for functional immaturity. Blood 1994, 84:4333-4343.
    • (1994) Blood , vol.84 , pp. 4333-4343
    • Hunt, D.W.1    Huppertz, H.I.2    Jiang, H.J.3    Petty, R.E.4
  • 124
    • 1642581673 scopus 로고    scopus 로고
    • Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns
    • De Wit D., Olislagers V., Goriely S., Vermeulen F., Wagner H., Goldman M., et al. Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns. Blood 2004, 103:1030-1032.
    • (2004) Blood , vol.103 , pp. 1030-1032
    • De Wit, D.1    Olislagers, V.2    Goriely, S.3    Vermeulen, F.4    Wagner, H.5    Goldman, M.6
  • 125
    • 0242655092 scopus 로고    scopus 로고
    • Impaired responses to toll-like receptor 4 and toll-like receptor 3 ligands in human cord blood
    • De Wit D., Tonon S., Olislagers V., Goriely S., Boutriaux M., Goldman M., et al. Impaired responses to toll-like receptor 4 and toll-like receptor 3 ligands in human cord blood. J. Autoimmun. 2003, 21:277-281.
    • (2003) J. Autoimmun. , vol.21 , pp. 277-281
    • De Wit, D.1    Tonon, S.2    Olislagers, V.3    Goriely, S.4    Boutriaux, M.5    Goldman, M.6
  • 126
    • 42249109065 scopus 로고    scopus 로고
    • Interferon regulatory factor 7-mediated responses are defective in cord blood plasmacytoid dendritic cells
    • Danis B., George T.C., Goriely S., Dutta B., Renneson J., Gatto L., et al. Interferon regulatory factor 7-mediated responses are defective in cord blood plasmacytoid dendritic cells. Eur. J. Immunol. 2008, 38:507-517.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 507-517
    • Danis, B.1    George, T.C.2    Goriely, S.3    Dutta, B.4    Renneson, J.5    Gatto, L.6
  • 127
    • 33747201640 scopus 로고    scopus 로고
    • Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells
    • Levy O., Suter E.E., Miller R.L., Wessels M.R. Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells. Blood 2006, 108:1284-1290.
    • (2006) Blood , vol.108 , pp. 1284-1290
    • Levy, O.1    Suter, E.E.2    Miller, R.L.3    Wessels, M.R.4
  • 128
    • 0036498917 scopus 로고    scopus 로고
    • Efficient in vivo priming of specific cytotoxic T cell responses by neonatal dendritic cells
    • Dadaglio G., Sun C.M., Lo-Man R., Siegrist C., Leclerc C. Efficient in vivo priming of specific cytotoxic T cell responses by neonatal dendritic cells. J. Immunol. 2002, 168:2219-2224.
    • (2002) J. Immunol. , vol.168 , pp. 2219-2224
    • Dadaglio, G.1    Sun, C.M.2    Lo-Man, R.3    Siegrist, C.4    Leclerc, C.5
  • 129
    • 0141840799 scopus 로고    scopus 로고
    • Efficient priming of antigen-specific cytotoxic T lymphocytes by human cord blood dendritic cells
    • Salio M., Dulphy N., Renneson J., Herbert M., McMichael A., Marchant A., et al. Efficient priming of antigen-specific cytotoxic T lymphocytes by human cord blood dendritic cells. Int. Immunol. 2003, 15:1265-1273.
    • (2003) Int. Immunol. , vol.15 , pp. 1265-1273
    • Salio, M.1    Dulphy, N.2    Renneson, J.3    Herbert, M.4    McMichael, A.5    Marchant, A.6
  • 130
    • 3442877562 scopus 로고    scopus 로고
    • Treatment of neonatal mice with Flt3 ligand leads to changes in dendritic cell subpopulations associated with enhanced IL-12 and IFN-α production
    • Vollstedt S., O'Keeffe M., Odermatt B., Beat R., Glanzmann B., Riesen M., et al. Treatment of neonatal mice with Flt3 ligand leads to changes in dendritic cell subpopulations associated with enhanced IL-12 and IFN-α production. Eur. J. Immunol. 2004, 34:1849-1860.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 1849-1860
    • Vollstedt, S.1    O'Keeffe, M.2    Odermatt, B.3    Beat, R.4    Glanzmann, B.5    Riesen, M.6
  • 131
    • 53349171450 scopus 로고    scopus 로고
    • Delayed maturation of an IL-12-producing dendritic cell subset explains the early Th2 bias in neonatal immunity
    • Lee H.H., Hoeman C.M., Hardaway J.C., Guloglu F.B., Ellis J.S., Jain R., et al. Delayed maturation of an IL-12-producing dendritic cell subset explains the early Th2 bias in neonatal immunity. J. Exp. Med. 2008, 205:2269-2280.
    • (2008) J. Exp. Med. , vol.205 , pp. 2269-2280
    • Lee, H.H.1    Hoeman, C.M.2    Hardaway, J.C.3    Guloglu, F.B.4    Ellis, J.S.5    Jain, R.6
  • 132
    • 15044345461 scopus 로고    scopus 로고
    • Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
    • Takaoka A., Yanai H., Kondo S., Duncan G., Negishi H., Mizutani T., et al. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 2005, 434:243-249.
    • (2005) Nature , vol.434 , pp. 243-249
    • Takaoka, A.1    Yanai, H.2    Kondo, S.3    Duncan, G.4    Negishi, H.5    Mizutani, T.6
  • 133
    • 31544456342 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation
    • Goriely S., Molle C., Nguyen M., Albarani V., Haddou N.O., Lin R., et al. Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation. Blood 2006, 107:1078-1084.
    • (2006) Blood , vol.107 , pp. 1078-1084
    • Goriely, S.1    Molle, C.2    Nguyen, M.3    Albarani, V.4    Haddou, N.O.5    Lin, R.6
  • 134
    • 0036242980 scopus 로고    scopus 로고
    • Neonatal dendritic cells are intrinsically biased against Th-1 immune responses
    • Langrish C.L., Buddle J.C., Thrasher A.J., Goldblatt D. Neonatal dendritic cells are intrinsically biased against Th-1 immune responses. Clin. Exp. Immunol. 2002, 128:118-123.
    • (2002) Clin. Exp. Immunol. , vol.128 , pp. 118-123
    • Langrish, C.L.1    Buddle, J.C.2    Thrasher, A.J.3    Goldblatt, D.4
  • 135
    • 0035253702 scopus 로고    scopus 로고
    • Deficient IL-12(p35) gene expression by dendritic cells derived from neonatal monocytes
    • Goriely S., Vincart B., Stordeur P., Vekemans J., Willems F., Goldman M., et al. Deficient IL-12(p35) gene expression by dendritic cells derived from neonatal monocytes. J. Immunol. 2001, 166:2141-2146.
    • (2001) J. Immunol. , vol.166 , pp. 2141-2146
    • Goriely, S.1    Vincart, B.2    Stordeur, P.3    Vekemans, J.4    Willems, F.5    Goldman, M.6
  • 136
    • 0036857834 scopus 로고    scopus 로고
    • Bordetella pertussis toxin induces the release of inflammatory cytokines and dendritic cell activation in whole blood: impaired responses in human newborns
    • Tonon S., Goriely S., Aksoy E., Pradier O., Del Giudice G., Trannoy E., et al. Bordetella pertussis toxin induces the release of inflammatory cytokines and dendritic cell activation in whole blood: impaired responses in human newborns. Eur. J. Immunol. 2002, 32:3118-3125.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 3118-3125
    • Tonon, S.1    Goriely, S.2    Aksoy, E.3    Pradier, O.4    Del Giudice, G.5    Trannoy, E.6
  • 137
    • 1842732225 scopus 로고    scopus 로고
    • A defect in nucleosome remodeling prevents IL-12(p35) gene transcription in neonatal dendritic cells
    • Goriely S., Van Lint C., Dadkhah R., Libin M., De Wit D., Demonté D., et al. A defect in nucleosome remodeling prevents IL-12(p35) gene transcription in neonatal dendritic cells. J. Exp. Med. 2004, 199:1011-1016.
    • (2004) J. Exp. Med. , vol.199 , pp. 1011-1016
    • Goriely, S.1    Van Lint, C.2    Dadkhah, R.3    Libin, M.4    De Wit, D.5    Demonté, D.6
  • 139
    • 35349008098 scopus 로고    scopus 로고
    • Combined Toll-like receptor agonists synergistically increase production of inflammatory cytokines in human neonatal dendritic cells
    • Krumbiegel D., Zepp F., Meyer C.U. Combined Toll-like receptor agonists synergistically increase production of inflammatory cytokines in human neonatal dendritic cells. Hum. Immunol. 2007, 68:813-822.
    • (2007) Hum. Immunol. , vol.68 , pp. 813-822
    • Krumbiegel, D.1    Zepp, F.2    Meyer, C.U.3
  • 140
    • 84937520916 scopus 로고    scopus 로고
    • Zymosan induces immune responses comparable with those of adults in monocytes, dendritic cells, and monocyte-derived dendritic cells from cord blood
    • (e1-2)
    • Nohmi K., Tokuhara D., Tachibana D., Saito M., Sakashita Y., Nakano A., et al. Zymosan induces immune responses comparable with those of adults in monocytes, dendritic cells, and monocyte-derived dendritic cells from cord blood. J. Pediatr. 2015, 167:155-162. (e1-2).
    • (2015) J. Pediatr. , vol.167 , pp. 155-162
    • Nohmi, K.1    Tokuhara, D.2    Tachibana, D.3    Saito, M.4    Sakashita, Y.5    Nakano, A.6
  • 141
    • 33947606977 scopus 로고    scopus 로고
    • Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells
    • Aksoy E., Albarani V., Nguyen M., Laes J.F., Ruelle J.L., De Wit D., et al. Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells. Blood 2007, 109:2887-2893.
    • (2007) Blood , vol.109 , pp. 2887-2893
    • Aksoy, E.1    Albarani, V.2    Nguyen, M.3    Laes, J.F.4    Ruelle, J.L.5    De Wit, D.6
  • 147
    • 33947590063 scopus 로고    scopus 로고
    • Whatever turns you on: accessory-cell-dependent activation of NK cells by pathogens
    • Newman K.C., Riley E.M. Whatever turns you on: accessory-cell-dependent activation of NK cells by pathogens. Nat. Rev. Immunol. 2007, 7:279-291.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 279-291
    • Newman, K.C.1    Riley, E.M.2
  • 148
    • 77956917869 scopus 로고    scopus 로고
    • Primed antigen-specific CD4+ T cells are required for NK cell activation in vivo upon Leishmania major infection
    • Bihl F., Pecheur J., Bréart B., Poupon G., Cazareth J., Julia V. Primed antigen-specific CD4+ T cells are required for NK cell activation in vivo upon Leishmania major infection. J. Immunol. 2010, 185:2174-2181.
    • (2010) J. Immunol. , vol.185 , pp. 2174-2181
    • Bihl, F.1    Pecheur, J.2    Bréart, B.3    Poupon, G.4    Cazareth, J.5    Julia, V.6
  • 150
    • 0033854779 scopus 로고    scopus 로고
    • Intracellular cytokine profile of cord blood T-, and NK- cells and monocytes
    • Krampera M., Tavecchia L., Benedetti F., Nadali G., Pizzolo G. Intracellular cytokine profile of cord blood T-, and NK- cells and monocytes. Haematologica 2000, 85:675-679.
    • (2000) Haematologica , vol.85 , pp. 675-679
    • Krampera, M.1    Tavecchia, L.2    Benedetti, F.3    Nadali, G.4    Pizzolo, G.5
  • 151
    • 0030064563 scopus 로고    scopus 로고
    • Interleukin-12 induces interferon-gamma expression and natural killer cytotoxicity in cord blood mononuclear cells
    • Lau A.S., Sigaroudinia M., Yeung M.C., Kohl S. Interleukin-12 induces interferon-gamma expression and natural killer cytotoxicity in cord blood mononuclear cells. Pediatr. Res. 1996, 39:150-155.
    • (1996) Pediatr. Res. , vol.39 , pp. 150-155
    • Lau, A.S.1    Sigaroudinia, M.2    Yeung, M.C.3    Kohl, S.4
  • 154
    • 39149085387 scopus 로고    scopus 로고
    • High expression of NKG2A/CD94 and low expression of granzyme B are associated with reduced cord blood NK cell activity
    • Wang Y., Xu H., Zheng X., Wei H., Sun R., Tian Z. High expression of NKG2A/CD94 and low expression of granzyme B are associated with reduced cord blood NK cell activity. Cell. Mol. Immunol. 2007, 4:377-382.
    • (2007) Cell. Mol. Immunol. , vol.4 , pp. 377-382
    • Wang, Y.1    Xu, H.2    Zheng, X.3    Wei, H.4    Sun, R.5    Tian, Z.6
  • 155
    • 17744367418 scopus 로고    scopus 로고
    • Characterization of cord blood natural killer cells: implications for transplantation and neonatal infections
    • Dalle J.H., Menezes J., Wagner É., Blagdon M., Champagne J., Champagne M.A., et al. Characterization of cord blood natural killer cells: implications for transplantation and neonatal infections. Pediatr. Res. 2005, 57:649-655.
    • (2005) Pediatr. Res. , vol.57 , pp. 649-655
    • Dalle, J.H.1    Menezes, J.2    Wagner, É.3    Blagdon, M.4    Champagne, J.5    Champagne, M.A.6
  • 156
    • 39149085387 scopus 로고    scopus 로고
    • High expression of NKG2A/CD94 and low expression of granzyme B are associated with reduced cord blood NK cell activity
    • Wang Y., Xu H., Zheng X., Wei H., Sun R., Tian Z. High expression of NKG2A/CD94 and low expression of granzyme B are associated with reduced cord blood NK cell activity. Cell. Mol. Immunol. 2007, 4:377-382.
    • (2007) Cell. Mol. Immunol. , vol.4 , pp. 377-382
    • Wang, Y.1    Xu, H.2    Zheng, X.3    Wei, H.4    Sun, R.5    Tian, Z.6
  • 157
    • 84863116715 scopus 로고    scopus 로고
    • Effect of influenza A infection on umbilical cord blood natural killer function regulation with interleukin-15
    • Lin S.J., Cheng P.J., Lin T.Y., Lee P.T., Hsiao H.S., Kuo M.L. Effect of influenza A infection on umbilical cord blood natural killer function regulation with interleukin-15. J. Infect. Dis. 2012, 205:745-756.
    • (2012) J. Infect. Dis. , vol.205 , pp. 745-756
    • Lin, S.J.1    Cheng, P.J.2    Lin, T.Y.3    Lee, P.T.4    Hsiao, H.S.5    Kuo, M.L.6
  • 158
    • 0038798483 scopus 로고    scopus 로고
    • Analysis of natural killer (NK) cell activity and adhesion molecules on NK cells from umbilical cord blood
    • Tanaka H., Kai S., Yamaguchi M., Misawa M., Fujimori Y., Yamamoto M., et al. Analysis of natural killer (NK) cell activity and adhesion molecules on NK cells from umbilical cord blood. Eur. J. Haematol. 2003, 71:29-38.
    • (2003) Eur. J. Haematol. , vol.71 , pp. 29-38
    • Tanaka, H.1    Kai, S.2    Yamaguchi, M.3    Misawa, M.4    Fujimori, Y.5    Yamamoto, M.6
  • 159
    • 0032703698 scopus 로고    scopus 로고
    • Adhesion defects of antibody-mediated target cell binding of neonatal natural killer cells
    • Kohl S., Sigouroudinia M., Engleman E.G. Adhesion defects of antibody-mediated target cell binding of neonatal natural killer cells. Pediatr. Res. 1999, 46:755-759.
    • (1999) Pediatr. Res. , vol.46 , pp. 755-759
    • Kohl, S.1    Sigouroudinia, M.2    Engleman, E.G.3
  • 160
    • 0032945045 scopus 로고    scopus 로고
    • NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells
    • Sivori S., Pende D., Bottino C., Marcenaro E., Pessino A., Biassoni R., et al. NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells. Eur. J. Immunol. 1999, 29:1656-1666.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 1656-1666
    • Sivori, S.1    Pende, D.2    Bottino, C.3    Marcenaro, E.4    Pessino, A.5    Biassoni, R.6
  • 161
    • 0032078389 scopus 로고    scopus 로고
    • Interleukin (IL)-15 enhances antibody-dependent cellular cytotoxicity and natural killer activity in neonatal cells
    • Nguyen Q.H., Roberts R.L., Ank B.J., Lin S.J., Thomas E.K., Stiehm E.R. Interleukin (IL)-15 enhances antibody-dependent cellular cytotoxicity and natural killer activity in neonatal cells. Cell. Immunol. 1998, 185:83-92.
    • (1998) Cell. Immunol. , vol.185 , pp. 83-92
    • Nguyen, Q.H.1    Roberts, R.L.2    Ank, B.J.3    Lin, S.J.4    Thomas, E.K.5    Stiehm, E.R.6
  • 162
    • 0028296532 scopus 로고
    • Cytokine-enhanced NK cell-mediated cytotoxicity. Positive modulatory effects of IL-2 and IL-12 on stimulus-dependent granule exocytosis
    • Bonnema J.D., Rivlin K.A., Ting A.T., Schoon R.A., Abraham R.T., Leibson P.J. Cytokine-enhanced NK cell-mediated cytotoxicity. Positive modulatory effects of IL-2 and IL-12 on stimulus-dependent granule exocytosis. J. Immunol. 1994, 152:2098-2104.
    • (1994) J. Immunol. , vol.152 , pp. 2098-2104
    • Bonnema, J.D.1    Rivlin, K.A.2    Ting, A.T.3    Schoon, R.A.4    Abraham, R.T.5    Leibson, P.J.6
  • 163
    • 0028116922 scopus 로고
    • The lack of NK cytotoxicity associated with fresh HUCB may be due to the presence of soluble HLA in the serum
    • Webb B.J., Bochan M.R., Montel A., Padilla L.M., Brahmi Z. The lack of NK cytotoxicity associated with fresh HUCB may be due to the presence of soluble HLA in the serum. Cell. Immunol. 1994, 159:246-261.
    • (1994) Cell. Immunol. , vol.159 , pp. 246-261
    • Webb, B.J.1    Bochan, M.R.2    Montel, A.3    Padilla, L.M.4    Brahmi, Z.5
  • 165
    • 0024505507 scopus 로고
    • Human newborn natural killer cell responses to activation by monoclonal antibodies. Effect of culture with herpes simplex virus
    • Hayward A., Laszlo M., Vafai A. Human newborn natural killer cell responses to activation by monoclonal antibodies. Effect of culture with herpes simplex virus. J. Immunol. 1989, 142:1139-1143.
    • (1989) J. Immunol. , vol.142 , pp. 1139-1143
    • Hayward, A.1    Laszlo, M.2    Vafai, A.3
  • 166
    • 9344222211 scopus 로고    scopus 로고
    • Neonatal natural killer cells produce chemokines and suppress HIV replication in vitro
    • Bernstein H.B., Kinter A.L., Jackson R., Fauci A.S. Neonatal natural killer cells produce chemokines and suppress HIV replication in vitro. AIDS Res. Hum. Retroviruses 2004, 20:1189-1195.
    • (2004) AIDS Res. Hum. Retroviruses , vol.20 , pp. 1189-1195
    • Bernstein, H.B.1    Kinter, A.L.2    Jackson, R.3    Fauci, A.S.4
  • 167
    • 0034815728 scopus 로고    scopus 로고
    • Functional analyses of cord blood natural killer cells and T cells: a distinctive interleukin-18 response
    • Nomura A., Takada H., Jin C.H., Tanaka T., Ohga S., Hara T. Functional analyses of cord blood natural killer cells and T cells: a distinctive interleukin-18 response. Exp. Hematol. 2001, 29:1169-1176.
    • (2001) Exp. Hematol. , vol.29 , pp. 1169-1176
    • Nomura, A.1    Takada, H.2    Jin, C.H.3    Tanaka, T.4    Ohga, S.5    Hara, T.6
  • 168
    • 0035862163 scopus 로고    scopus 로고
    • Prostaglandin E2 suppressed IL-15-mediated human NK cell function through down-regulation of common gamma-chain
    • Joshi P.C., Zhou X., Cuchens M., Jones Q. Prostaglandin E2 suppressed IL-15-mediated human NK cell function through down-regulation of common gamma-chain. J. Immunol. 2001, 166:885-891.
    • (2001) J. Immunol. , vol.166 , pp. 885-891
    • Joshi, P.C.1    Zhou, X.2    Cuchens, M.3    Jones, Q.4
  • 169
    • 4043089285 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells inhibit cytotoxic activity of T CD8+ and NK lymphocytes in the direct cell-to-cell interaction
    • Trzonkowski P., Szmit E., Myśliwska J., Dobyszuk A., Myśliwski A. CD4+CD25+ T regulatory cells inhibit cytotoxic activity of T CD8+ and NK lymphocytes in the direct cell-to-cell interaction. Clin. Immunol. 2004, 112:258-267.
    • (2004) Clin. Immunol. , vol.112 , pp. 258-267
    • Trzonkowski, P.1    Szmit, E.2    Myśliwska, J.3    Dobyszuk, A.4    Myśliwski, A.5
  • 171
    • 84860419978 scopus 로고    scopus 로고
    • Off to a slow start: under-development of the complement system in term newborns is more substantial following premature birth
    • McGreal E.P., Hearne K., Spiller O.B. Off to a slow start: under-development of the complement system in term newborns is more substantial following premature birth. Immunobiology 2012, 217:176-186.
    • (2012) Immunobiology , vol.217 , pp. 176-186
    • McGreal, E.P.1    Hearne, K.2    Spiller, O.B.3
  • 173
    • 0018838613 scopus 로고
    • The complement system of the newborn infant
    • Drew J.H., Arroyave C.M. The complement system of the newborn infant. Biol. Neonate 1980, 37:209-217.
    • (1980) Biol. Neonate , vol.37 , pp. 209-217
    • Drew, J.H.1    Arroyave, C.M.2
  • 175
    • 84858590043 scopus 로고    scopus 로고
    • Neonatal plasma polarizes TLR4-mediated cytokine responses towards low IL-12p70 and high IL-10 production via distinct factors
    • Belderbos M.E., Levy O., Stalpers F., Kimpen J.L., Meyaard L., Bont L. Neonatal plasma polarizes TLR4-mediated cytokine responses towards low IL-12p70 and high IL-10 production via distinct factors. PLoS One 2012, 7:e33419.
    • (2012) PLoS One , vol.7 , pp. e33419
    • Belderbos, M.E.1    Levy, O.2    Stalpers, F.3    Kimpen, J.L.4    Meyaard, L.5    Bont, L.6
  • 176
    • 0034868248 scopus 로고    scopus 로고
    • The mannan-binding lectin pathway of complement activation: biology and disease association
    • Petersen S.V., Thiel S., Jensenius J.C. The mannan-binding lectin pathway of complement activation: biology and disease association. Mol. Immunol. 2001, 38:133-149.
    • (2001) Mol. Immunol. , vol.38 , pp. 133-149
    • Petersen, S.V.1    Thiel, S.2    Jensenius, J.C.3
  • 177
    • 0034999785 scopus 로고    scopus 로고
    • Mannose-binding lectin: targeting the microbial world for complement attack and opsonophagocytosis
    • Jack D.L., Klein N.J., Turner M.W. Mannose-binding lectin: targeting the microbial world for complement attack and opsonophagocytosis. Immunol. Rev. 2001, 180:86-99.
    • (2001) Immunol. Rev. , vol.180 , pp. 86-99
    • Jack, D.L.1    Klein, N.J.2    Turner, M.W.3
  • 178
    • 79955508081 scopus 로고    scopus 로고
    • Serum concentrations of lectin-pathway components in healthy neonates, children and adults: mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2)
    • Sallenbach S., Thiel S., Aebi C., Otth M., Bigler S., Jensenius J.C., et al. Serum concentrations of lectin-pathway components in healthy neonates, children and adults: mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2). Pediatr. Allergy Immunol. 2011, 22:424-430.
    • (2011) Pediatr. Allergy Immunol. , vol.22 , pp. 424-430
    • Sallenbach, S.1    Thiel, S.2    Aebi, C.3    Otth, M.4    Bigler, S.5    Jensenius, J.C.6
  • 179
    • 64149087423 scopus 로고    scopus 로고
    • Mannan-binding lectin-associated serine protease-2 (MASP-2) in a large cohort of neonates and its clinical associations
    • Swierzko A., Cedzynski M., Domzalska-Popadiuk I., MacDonald S.L., Borkowska-Klos M., Atkinson A.P., et al. Mannan-binding lectin-associated serine protease-2 (MASP-2) in a large cohort of neonates and its clinical associations. Mol. Immunol. 2009, 46:1696-1701.
    • (2009) Mol. Immunol. , vol.46 , pp. 1696-1701
    • Swierzko, A.1    Cedzynski, M.2    Domzalska-Popadiuk, I.3    MacDonald, S.L.4    Borkowska-Klos, M.5    Atkinson, A.P.6
  • 180
    • 84859723316 scopus 로고    scopus 로고
    • Factors of the lectin pathway of complement activation and their clinical associations in neonates
    • Cedzynski M., Swierzko A.S., Kilpatrick D.C. Factors of the lectin pathway of complement activation and their clinical associations in neonates. J. Biomed. Biotechnol. 2012, 2012:363246.
    • (2012) J. Biomed. Biotechnol. , vol.2012 , pp. 363246
    • Cedzynski, M.1    Swierzko, A.S.2    Kilpatrick, D.C.3
  • 181
  • 184
    • 0030764936 scopus 로고    scopus 로고
    • Serum fibronectin in neonatal sepsis: is it valuable in early diagnosis and outcome prediction?
    • Koçak U., Ezer U., Vidinlisan S. Serum fibronectin in neonatal sepsis: is it valuable in early diagnosis and outcome prediction?. Acta Paediatr. Jpn. 1997, 39:428-432.
    • (1997) Acta Paediatr. Jpn. , vol.39 , pp. 428-432
    • Koçak, U.1    Ezer, U.2    Vidinlisan, S.3
  • 186
    • 0025351488 scopus 로고
    • Role of fibronectin in diseases of newborn infants and children
    • Polin R.A. Role of fibronectin in diseases of newborn infants and children. Rev. Infect. Dis. 1990, 12(Suppl. 4):S428-38.
    • (1990) Rev. Infect. Dis. , vol.12 , pp. S428-S438
    • Polin, R.A.1
  • 188
    • 0033820684 scopus 로고    scopus 로고
    • Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms
    • Haskó G., Kuhel D.G., Chen J.F., Schwarzschild M.A., Deitch E.A., Mabley J.G., et al. Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms. FASEB J. 2000, 14:2065-2074.
    • (2000) FASEB J. , vol.14 , pp. 2065-2074
    • Haskó, G.1    Kuhel, D.G.2    Chen, J.F.3    Schwarzschild, M.A.4    Deitch, E.A.5    Mabley, J.G.6
  • 189
    • 84937391124 scopus 로고    scopus 로고
    • Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension
    • Karmouty-Quintana H., Philip K., Acero L.F., Chen N.Y., Weng T., Molina J.G., et al. Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension. FASEB J. 2015, 29:50-60.
    • (2015) FASEB J. , vol.29 , pp. 50-60
    • Karmouty-Quintana, H.1    Philip, K.2    Acero, L.F.3    Chen, N.Y.4    Weng, T.5    Molina, J.G.6
  • 190
    • 84864953756 scopus 로고    scopus 로고
    • Different modulating effects of adenosine on neonatal and adult polymorphonuclear leukocytes
    • (Article ID 387923)
    • Hou P.C., Yu H.R., Kuo H.C., Wang L., Lin L.Y., Sheen J.M., et al. Different modulating effects of adenosine on neonatal and adult polymorphonuclear leukocytes. Sci. World J. 2012, 2012. (Article ID 387923).
    • (2012) Sci. World J. , vol.2012
    • Hou, P.C.1    Yu, H.R.2    Kuo, H.C.3    Wang, L.4    Lin, L.Y.5    Sheen, J.M.6
  • 191
    • 0025190892 scopus 로고
    • Interleukin-6 and the acute phase response
    • Heinrich P.C., Castell J.V., Andus T. Interleukin-6 and the acute phase response. Biochem. J. 1990, 265:621-636.
    • (1990) Biochem. J. , vol.265 , pp. 621-636
    • Heinrich, P.C.1    Castell, J.V.2    Andus, T.3
  • 192
    • 33646170919 scopus 로고    scopus 로고
    • Passive and active components of neonatal innate immune defenses
    • Firth M., Shewen P., Hodgins D. Passive and active components of neonatal innate immune defenses. Anim. Health Res. Rev. 2005, 6:143-158.
    • (2005) Anim. Health Res. Rev. , vol.6 , pp. 143-158
    • Firth, M.1    Shewen, P.2    Hodgins, D.3
  • 194
    • 84873595707 scopus 로고    scopus 로고
    • Neonatal levels of acute phase proteins and later risk of non-affective psychosis
    • Gardner R.M., Dalman C., Wicks S., Lee B.K., Karlsson H. Neonatal levels of acute phase proteins and later risk of non-affective psychosis. Transl. Psychiatry 2013, 3:e228.
    • (2013) Transl. Psychiatry , vol.3 , pp. e228
    • Gardner, R.M.1    Dalman, C.2    Wicks, S.3    Lee, B.K.4    Karlsson, H.5
  • 195
    • 84922572664 scopus 로고    scopus 로고
    • Antimicrobial protein and peptide concentrations and activity in human breast milk consumed by preterm infants at risk of late-onset neonatal sepsis
    • Trend S., Strunk T., Hibbert J., Kok C., Zhang G., Doherty D., et al. Antimicrobial protein and peptide concentrations and activity in human breast milk consumed by preterm infants at risk of late-onset neonatal sepsis. PLoS One 2015, 10:e0117038.
    • (2015) PLoS One , vol.10 , pp. e0117038
    • Trend, S.1    Strunk, T.2    Hibbert, J.3    Kok, C.4    Zhang, G.5    Doherty, D.6
  • 197
    • 84929078863 scopus 로고    scopus 로고
    • The role of myeloid-derived suppressor cells in immune ontogeny
    • Gantt S., Gervassi A., Jaspan H., Horton H. The role of myeloid-derived suppressor cells in immune ontogeny. Front. Immunol. 2014, 5:387.
    • (2014) Front. Immunol. , vol.5 , pp. 387
    • Gantt, S.1    Gervassi, A.2    Jaspan, H.3    Horton, H.4
  • 198
    • 84897019347 scopus 로고    scopus 로고
    • Expression profile of cord blood neutrophils and dysregulation of HSPA1A and OLR1 upon challenge by bacterial peptidoglycan
    • Fong O.N., Chan K.Y., Leung K.T., Lam H.S., Cheung H.M., Leung T.Y., et al. Expression profile of cord blood neutrophils and dysregulation of HSPA1A and OLR1 upon challenge by bacterial peptidoglycan. J. Leukoc. Biol. 2014, 95:169-178.
    • (2014) J. Leukoc. Biol. , vol.95 , pp. 169-178
    • Fong, O.N.1    Chan, K.Y.2    Leung, K.T.3    Lam, H.S.4    Cheung, H.M.5    Leung, T.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.