Zymosan induces immune responses comparable with those of adults in monocytes, dendritic cells, and monocyte-derived dendritic cells from cord blood

Journal of Pediatrics

Volumn 167, Issue 1, 2015, Pages 155-162.e2

  Nohmi, Kyoko ^a   Tokuhara, Daisuke ^a   Tachibana, Daisuke ^a   Saito, Mika ^a   Sakashita, Yuko ^a   Nakano, Akemi ^a   Terada, Hiroyuki ^a   Katayama, Hiroko ^a   Koyama, Masayasu ^a   Shintaku, Haruo ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FLAGELLIN; IMIQUIMOD; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; ZYMOSAN; AMINOQUINOLINE DERIVATIVE; CPG-OLIGONUCLEOTIDE; CYTOKINE; IMMUNOLOGICAL ADJUVANT; LIPOPEPTIDE; OLIGODEOXYRIBONUCLEOTIDE; PAM(3)CSK(4) PEPTIDE;

ADULT; ARTICLE; BLOOD; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INNATE IMMUNITY; MALE; MONOCYTE; MONOCYTE DERIVED DENDRITIC CELL; NEWBORN; PRIORITY JOURNAL; UMBILICAL CORD BLOOD; CELL CULTURE; CYTOLOGY; FETUS BLOOD; FLOW CYTOMETRY; IMMUNOLOGY; METABOLISM;

ADJUVANTS, IMMUNOLOGIC; ADULT; AMINOQUINOLINES; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; FETAL BLOOD; FLAGELLIN; FLOW CYTOMETRY; HUMANS; INFANT, NEWBORN; LIPOPEPTIDES; LIPOPOLYSACCHARIDES; MONOCYTES; OLIGODEOXYRIBONUCLEOTIDES; POLY I-C; ZYMOSAN;

EID: 84937520916     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2015.03.035     Document Type: Article

References (40)

1. J.E. Lawn, S. Cousens, and J. Zupan Lancet Neonatal Survival Steering Team. 4 million neonatal deaths: when? Where? Why? Lancet 365 2005 891 900
2. H. Nair, D.J. Nokes, B.D. Gessner, M. Dherani, S.A. Madhi, R.J. Singleton, and et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis Lancet 375 2010 1545 1555
3. D.I. Bernstein, R.I. Glass, G. Rodgers, B.L. Davidson, and D.A. Sack Evaluation of rhesus rotavirus monovalent and tetravalent reassortant vaccines in US children. US Rotavirus Vaccine Efficacy Group JAMA 273 1995 1191 1196
4. R.B. Belshe, P.M. Mendelman, J. Treanor, J. King, W.C. Gruber, P. Piedra, and et al. The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children N Engl J Med 338 1998 1405 1412
5. P.M. Mendelman, J. Cordova, and I. Cho Safety, efficacy and effectiveness of the influenza virus vaccine, trivalent, types A and B, live, cold-adapted (CAIV-T) in healthy children and healthy adults Vaccine 19 2001 2221 2226
6. D.R. Hill, L. Ford, and D.G. Lalloo Oral cholera vaccines: use in clinical practice Lancet Infect Dis 6 2006 361 373
7. World Health Organization Young Infants Study Group Conclusions from the WHO multicenter study of serious infections in young infants Pediatr Infect Dis J 18 1999 S32 S34
8. J. Klinge, S. Lugauer, K. Korn, U. Heininger, and K. Stehr Comparison of immunogenicity and reactogenicity of a measles, mumps and rubella (MMR) vaccine in German children vaccinated at 9-11, 12-14 or 15-17 months of age Vaccine 18 2000 3134 3140
9. J.M. Lieberman, D.P. Greenberg, V.K. Wong, S. Partridge, S.J. Chang, C.Y. Chiu, and et al. Effect of neonatal immunization with diphtheria and tetanus toxoids on antibody responses to Haemophilus influenzae type b conjugate vaccines J Pediatr 126 1995 198 205
10. H.A. Gans, Y. Maldonado, L.L. Yasukawa, J. Beeler, S. Audet, M.M. Rinki, and et al. IL-12, IFN-gamma, and T cell proliferation to measles in immunized infants J Immunol 162 1999 5569 5575
11. A. Iwasaki, and R. Medzhitov Toll-like receptor control of the adaptive immune responses Nat Immunol 5 2004 987 995
12. M. Nguyen, E. Leuridan, T. Zhang, D. De Wit, F. Willems, P. Van Damme, and et al. Acquisition of adult-like TLR4 and TLR9 responses during the first year of life PLoS One 5 2010 e10407
13. T.R. Kollmann, J. Crabtree, A. Rein-Weston, D. Blimkie, F. Thommai, X.Y. Wang, and et al. Neonatal innate TLR-mediated responses are distinct from those of adults J Immunol 183 2009 7150 7160
14. O. Levy, K.A. Zarember, R.M. Roy, C. Cywes, P.J. Godowski, and M.R. Wessels Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-alpha induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848 J Immunol 173 2004 4627 4634
15. D.D. Wit, S. Tonon, V. Olislagers, S. Goriely, M. Boutriaux, M. Goldman, and et al. Impaired responses to Toll-like receptor 4 and Toll-like receptor 3 ligands in human cord blood J Autoimmun 21 2003 277 281
16. M.E. Belderbos, G.M. van Bleek, O. Levy, M.O. Blanken, M.L. Houben, L. Schuijff, and et al. Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life Clin Immunol 133 2009 228 237
17. T.R. Kollmann, O. Levy, R.R. Montgomery, and S. Goriely Innate immune function by Toll-like receptors: distinct responses in newborns and the elderly Immunity 37 2012 771 783
18. + monocyte subset with high Toll-like receptor 4 expression in cord blood compared to adult blood contributes to lipopolysaccharide hyporesponsiveness in newborns Clin Vaccine Immunol 20 2013 962 971
19. + leukocytes acquire the phenotype and function of antigen-presenting dendritic cells when cultured in GM-CSF and IL-4 J Leukoc Biol 59 1996 208 218
20. R.D. Weeratna, S.R. Makinen, M.J. McCluskie, and H.L. Davis TLR agonists as vaccine adjuvants: comparison of CpG ODN and Resiquimod (R-848) Vaccine 23 2005 5263 5270
21. C. Cuadros, F.J. Lopez-Hernandez, A.L. Dominguez, M. McClelland, and J. Lustgarten Flagellin fusion proteins as adjuvants or vaccines induce specific immune responses Infect Immun 72 2004 2810 2816
22. Y. Ara, T. Saito, T. Takagi, E. Hagiwara, Y. Miyagi, M. Sugiyama, and et al. Zymosan enhances the immune response to DNA vaccine for human immunodeficiency virus type-1 through the activation of complement system Immunology 103 2001 98 105
23. A. Ainai, T. Ichinohe, S. Tamura, T. Kurata, T. Sata, M. Tashiro, and et al. Zymosan enhances the mucosal adjuvant activity of poly(I: C) in a nasal influenza vaccine J Med Virol 82 2010 476 484
24. S. Dillon, S. Agrawal, K. Banerjee, J. Letterio, T.L. Denning, K. Oswald-Richter, and et al. Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance J Clin Invest 116 2006 916 928
25. A. Mullard Vaccine failure explained Nature 2008 www.nature.com/news/2008/081212/full/news.2008.1302.html. Accessed April 27, 2015.
26. H.W. Kim, J.G. Canchola, C.D. Brandt, G. Pyles, R.M. Chanock, K. Jensen, and et al. Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine Am J Epidemiol 89 1969 422 434
27. P.J. Openshaw, F.J. Culley, and W. Olszewska Immunopathogenesis of vaccine-enhanced RSV disease Vaccine 20 2001 S27 S31
28. M.F. Delgado, S. Coviello, A.C. Monsalvo, G.A. Melendi, J.Z. Hernandez, J.P. Batalle, and et al. Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease Nat Med 15 2009 34 41
29. M.R. Murawski, G.N. Bowen, A.M. Cerny, L.J. Anderson, L.M. Haynes, R.A. Tripp, and et al. Respiratory syncytial virus activates innate immunity through Toll-like receptor 2 J Virol 83 2009 1492 1500
30. J.A. Talcott, D.B. Ness, and F.C. Grumet Adjuvant effect of LPS on in vivo antibody response: genetic defect in C3H/HeJ mice Immunogenetics 2 1975 507 515
31. E.M. Coccia, M. Severa, E. Giacomini, D. Monneron, M.E. Remoli, I. Julkunen, and et al. Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells Eur J Immunol 34 2004 796 805
32. F. Geissmann, M.G. Manz, S. Jung, M.H. Sieweke, M. Merad, and K. Ley Development of monocytes, macrophages, and dendritic cells Science 327 2010 656 661
33. J. Banchereau, and R.M. Steinman Dendritic cells and the control of immunity Nature 392 1998 245 252
34. M. Cella, A. Engering, V. Pinet, J. Pieters, and A. Lanzavecchia Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells Nature 388 1997 782 787
35. T.E. Singleton, P. Massari, and L.M. Wetzler Neisserial porin-induced dendritic cell activation is MyD88 and TLR2 dependent J Immunol 174 2005 3545 3550
36. D.P. Simmons, D.H. Canaday, Y. Liu, Q. Li, A. Huang, W.H. Boom, and et al. Mycobacterium tuberculosis and TLR2 agonists inhibit induction of type I IFN and class I MHC antigen cross-processing by TLR9 J Immunol 185 2010 2405 2415
37. A. Dolganiuc, S. Chang, K. Kodys, P. Mandrekar, G. Bakis, M. Cormier, and et al. Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection J Immunol 177 2006 6758 6768
38. L. Alexopoulou, V. Thomas, M. Schnare, Y. Lobet, J. Anguita, R.T. Schoen, and et al. Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice Nat Med 8 2002 878 884
39. K.B. Weatherstone, and E.A. Rich Tumor necrosis factor/cachectin and interleukin-1 secretion by cord blood monocytes from premature and term neonates Pediatr Res 25 1989 342 346
40. G. Buonocore, M. De Filippo, D. Gioia, E. Picciolini, E. Luzzi, V. Bocci, and et al. Maternal and neonatal plasma cytokine levels in relation to mode of delivery Biol Neonate 68 1995 104 110