Neonatal natural killer cells produce chemokines and suppress HIV replication in vitro

AIDS Research and Human Retroviruses

Volumn 20, Issue 11, 2004, Pages 1189-1195

  Bernstein, Helene B ^a,b   Kinter, Audrey L ^a   Jackson, Robert ^a   Fauci, Anthony S ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE;

ARTICLE; CELL KILLING; CONTROLLED STUDY; CYTOLYSIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE SYSTEM; LIGAND BINDING; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS REPLICATION;

ADULT; CD4-POSITIVE T-LYMPHOCYTES; CHEMOKINES; COCULTURE TECHNIQUES; FETAL BLOOD; HIV INFECTIONS; HIV-1; HUMANS; INFANT, NEWBORN; KILLER CELLS, NATURAL; MACROPHAGE INFLAMMATORY PROTEIN-1; RANTES; VIRUS REPLICATION;

EID: 9344222211     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/0889222042544983     Document Type: Article

References (34)

1. Connor EM, Sperling RS, Gelber R, Kiselev P, Scott G, O'Sullivan MJ, VanDyke R, Bey M, Shearer W, Jacobson RL, et al.: Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group. N Engl J Med 1994;331:1173-1180.
2. Peckham C and Gibb D: Mother-to-child transmission of the human immunodeficiency virus. N Engl J Med 1995;333:298-302.
3. Mofenson LM, Lambert JS, Stiehm ER, Bethel J, Meyer WA 3rd, Whitehouse J, Moye J Jr, Reichelderfer P, Harris DR, Fowler MG, Mathieson BJ, and Nemo GJ: Risk factors for perinatal transmission of human immunodeficiency virus type 1 in women treated with zidovudine. Pediatric AIDS Clinical Trials Group Study 185 Team. N Engl J Med 1999;341:385-393.
4. Kuhn L, Coutsoudis A, Moodley D, Trabattoni D, Mngqundaniso N, Shearer GM, Clerici M, Coovadia HM, and Stein Z: T-helper cell responses to HIV envelope peptides in cord blood: Protection against intrapartum and breast-feeding transmission. AIDS 2001; 15:1-9.
5. Rowland-Jones SL, Nixon DF, Aldhous MC, Gotch F, Ariyoshi K, Hallam N, Kroll JS, Froebel K, and McMichael A: HIV-specific cytotoxic T-cell activity in an HIV-exposed but uninfected infant. Lancet 1993;341:860-861.
6. Wasik TJ, Bratosiewicz J, Wierzbicki A, Whiteman VE, Rutstein RR, Starr SE, Douglas SD, Kaufman D, Sison AV, Polansky M, Lischner HW, and Kozbor D: Protective role of beta-chemokines associated with HIV-specific Th responses against perinatal HIV transmission. J Immunol 1999;162:4355-4364.
7. Economides A, Schmid I, Anisman-Posner DJ, Plaeger S, Bryson YJ, and Uittenbogaart CH: Apoptosis in cord blood T lymphocytes from infants of human immunodeficiency virus-infected mothers. Clin Diagn Lab Immunol 1998;5:230-234.
8. Rich KC, Siegel JN, Jennings C, Rydman RJ, and Landay AL: Function and phenotype of immature CD4+ lymphocytes in healthy infants and early lymphocyte activation in uninfected infants of human immunodeficiency virus-infected mothers. Clin Diagn Lab Immunol 1997;4:358-361.
9. Kuhn L, Coutsoudis A, Moodley D, Mngqundaniso N, Trabattoni D, Shearer GM, Clerici M, and Coovadia HM: Interferon-gamma and interleukin-10 production among HIV-1-infected and uninfected infants of HIV-1-infected mothers. Pediatr Res 2001;50:412-416.
10. Chougnet C, Kovacs A, Baker R, Mueller BU, Luban NL, Liewehr DJ, Steinberg SM, Thomas EK, and Shearer GM: Influence of human immunodeficiency virus-infected maternal environment on development of infant interleukin-12 production. J Infect Dis 2000; 181:1590-1597.
11. Rungruengthanakit K, Duerr A, Suriyanon V, Flowers L, Nagachinta T, Tansuhaj A, Kunangern D, de Boer M, and Nelson KE: Immune parameters among highly exposed, persistently seronegative (HEPS) Thai women. Abstracts XI International Conference on AIDS 1996;1:13.
12. Ahmad A and Menezes J: Positive correlation between the natural killer and gp 120/41-specific antibody-dependent cellular cytotoxic effector functions in HIV-infected individuals. J Acquir Immune Defic Syndr Hum Retrovirol 1995;10:115-119.
13. Brenner BG, Gornitsky M, and Wainberg MA: Interleukin-2-inducible natural immune (lymphokine-activated killer cell) responses as a functional correlate of progression to AIDS. Clin Diagn Lab Immunol 1994;1:538-544.
14. Ratcliffe LT, Lukey PT, MacKenzie CR, and Ress SR: Reduced NK activity correlates with active disease in HIV-patients with multidrug-resistant pulmonary tuberculosis. Clin Exp Immunol 1994; 97:373-379.
15. Zlotnik A and Yoshie O: Chemokines: A new classification system and their role in immunity. Immunity 2000;12:121-127.
16. Oliva A, Kinter AL, Vaccarezza M, Rubbert A, Catanzaro A, Moir S, Monaco J, Ehler L, Mizell S, Jackson R, Li Y, Romano JW, and Fauci AS: Natural killer cells from human immunodeficiency virus (HIV)-infected individuals are an important source of CC-chemokines and suppress HIV-1 entry and replication in vitro. J Clin Invest 1998;102:223-231.
17. Forthal DN, Landucci G, and Daar ES: Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cells. J Virol 2001;75:6953-6961.
18. Hariharan D, Ho W, Cutilli J, Campbell DE, and Douglas SD: C-C chemokine profile of cord blood mononuclear cells: Selective defect in RANTES production. Blood 2000;95:715-718.
19. Ziegner U, Campbell D, Weinhold K, Frank I, Rutstein R, and Starr SE: Deficient antibody-dependent cellular cytotoxicity against human immunodeficiency virus (HIV)-expressing target cells in perinatal HIV infection. Clin Diagn Lab Immunol 1999;6:718-724.
20. Jenkins M, Mills J, and Kohl S: Natural killer cytotoxicity and antibody-dependent cellular cytotoxicity of human immunodeficiency virus-infected cells by leukocytes from human neonates and adults. Pediatr Res 1993;33:469-474.
21. Kohl S, Loo LS, and Gonik B: Analysis in human neonates of defective antibody-dependent cellular cytotoxicity and natural killer cytotoxicity to herpes simplex virus-infected cells. J Infect Dis 1984;150:14-19.
22. Chun TW, Engel D, Berrey MM, Shea T, Corey L, and Fauci AS: Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection. Proc Natl Acad Sci USA 1998;95:8869-8873.
23. Willey RL, Smith DH, Lasky LA, Theodore TS, Earl PL, Moss B, Capon DJ, and Martin MA: In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity. J Virol 1988;62:139-147.
24. Shore SL, Milgrom H, Wood PA, and Nahmias AJ: Antibody-dependent cellular cytotoxicity to target cells infected with herpes simplex viruses: Functional adequacy in the neonate. Pediatrics 1977;59:22-28.
25. McConnachie PR, Rachelefsky G, Stiehm ER, and Terasaki PI: Antibody-dependent lymphocyte killer function and age. Pediatrics 1973;52:795-800.
26. Kohl S, Shaban SS, Starr SE, Wood PA, and Nahmias AJ: Human neonatal and maternal monocyte-macrophage and lymphocyte-mediated antibody-dependent cytotoxicity to cells infected with herpes simplex. J Pediatr 1978;93:206-210.
27. Kohl S, Frazier JJ, Greenberg SB, Pickering LK, and Loo LS: Interferon induction of natural killer cytotoxicity in human neonates. J Pediatr 1981;98:379-384.
28. Ching C and Lopez C: Natural killing of herpes simplex virus type 1-infected target cells: Normal human responses and influence of antiviral antibody. Infect Immun 1979;26:49-56.
29. Kottilil S, Chun TW, Moir S, Liu S, McLaughlin M, Hallahan CW, Maldarelli F, Corey L, and Fauci AS: Innate immunity in human immunodeficiency virus infection: Effect of viremia on natural killer cell function. J Infect Dis 2003;187:1038-1045.
30. Zhang L, Yu W, He T, Yu J, Caffrey RE, Dalmasso EA, Fu S, Pham T, Mei J, Ho JJ, Zhang W, Lopez P, and Ho DD: Contribution of human alpha-defensin 1, 2, and 3 to the anti-HIV-1 activity of CD8 antiviral factor. Science 2002;298:995-1000.
31. Pal R, Garzino-Demo A, Markham PD, Burns J, Brown M, Gallo RC, and DeVico AL: Inhibition of HIV-1 infection by the beta-chemokine MDC. Science 1997;278:695-698.
32. Yang OO and Walker BD: CD8+ cells in human immunodeficiency virus type I pathogenesis: Cytolytic and noncytolytic inhibition of viral replication. Adv Immunol 1997;66:273-311.
33. Moriuchi H, Moriuchi M, Combadiere C, Murphy PM, and Fauci AS: CD8+ T-cell-derived soluble factor(s), but not beta-chemokines RANTES, MIP-1 alpha, and MIP-1 beta, suppress HIV-1 replication in monocyte/macrophages. Proc Natl Acad Sci USA 1996;93:15341-15345.
34. Chun TW, Justement JS, Moir S, Hallahan CW, Ehler LA, Liu S, McLaughlin M, Dybul M, Mican JM, and Fauci AS: Suppression of HIV replication in the resting CD4+ T cell reservoir by autologous CD8+ T cells: Implications for the development of therapeutic strategies. Proc Natl Acad Sci USA 2001;98:253-258.