메뉴 건너뛰기




Volumn 22, Issue 2, 2017, Pages 296-305

Age and Alzheimer's disease gene expression profiles reversed by the glutamate modulator riluzole

Author keywords

[No Author keywords available]

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER 2; RILUZOLE; GLUTAMIC ACID; NEUROPROTECTIVE AGENT; TRANSCRIPTOME;

EID: 84961743204     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2016.33     Document Type: Article
Times cited : (87)

References (87)
  • 1
    • 5344271854 scopus 로고    scopus 로고
    • Memory and executive function in aging and AD: Multiple factors that cause decline and reserve factors that compensate
    • Buckner RL. Memory and executive function in aging and AD: multiple factors that cause decline and reserve factors that compensate. Neuron 2004; 44: 195-208.
    • (2004) Neuron , vol.44 , pp. 195-208
    • Buckner, R.L.1
  • 2
    • 29244439038 scopus 로고    scopus 로고
    • Neural plasticity in the ageing brain
    • Burke SN, Barnes CA. Neural plasticity in the ageing brain. Nat Rev Neurosci 2006; 7: 30-40.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 30-40
    • Burke, S.N.1    Barnes, C.A.2
  • 4
    • 0030698871 scopus 로고    scopus 로고
    • Life and death of neurons in the aging brain
    • Morrison JH, Hof PR. Life and death of neurons in the aging brain. Science 1997; 278: 412-419.
    • (1997) Science , vol.278 , pp. 412-419
    • Morrison, J.H.1    Hof, P.R.2
  • 5
    • 0036454496 scopus 로고    scopus 로고
    • Selective vulnerability of corticocortical and hippocampal circuits in aging and Alzheimer's disease
    • Morrison JH, Hof PR. Selective vulnerability of corticocortical and hippocampal circuits in aging and Alzheimer's disease. Prog Brain Res 2002; 136: 467-486.
    • (2002) Prog Brain Res , vol.136 , pp. 467-486
    • Morrison, J.H.1    Hof, P.R.2
  • 6
    • 37349016848 scopus 로고    scopus 로고
    • Synaptic plasticity, memory and the hippocampus: A neural network approach to causality
    • Neves G, Cooke SF, Bliss TV. Synaptic plasticity, memory and the hippocampus: a neural network approach to causality. Nat Rev Neurosci 2008; 9: 65-75.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 65-75
    • Neves, G.1    Cooke, S.F.2    Bliss, T.V.3
  • 7
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991; 82: 239-259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 8
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group
    • Bensimon G, Lacomblez L, Meininger V. A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N Engl J Med 1994; 330: 585-591.
    • (1994) N Engl J Med , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 9
    • 84924543911 scopus 로고    scopus 로고
    • Glutamatergic regulation prevents hippocampal-dependent age-related cognitive decline through dendritic spine clustering
    • Pereira AC, Lambert HK, Grossman YS, Dumitriu D, Waldman R, Jannetty SK, et al. Glutamatergic regulation prevents hippocampal-dependent age-related cognitive decline through dendritic spine clustering. Proc Natl Acad Sci USA 2014; 111: 18733-18738.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 18733-18738
    • Pereira, A.C.1    Lambert, H.K.2    Grossman, Y.S.3    Dumitriu, D.4    Waldman, R.5    Jannetty, S.K.6
  • 10
    • 0037180796 scopus 로고    scopus 로고
    • Long-term dendritic spine stability in the adult cortex
    • Grutzendler J, Kasthuri N, Gan WB. Long-term dendritic spine stability in the adult cortex. Nature 2002; 420: 812-816.
    • (2002) Nature , vol.420 , pp. 812-816
    • Grutzendler, J.1    Kasthuri, N.2    Gan, W.B.3
  • 11
    • 53949085530 scopus 로고    scopus 로고
    • Synaptic clustering by dendritic signalling mechanisms
    • Larkum ME, Nevian T. Synaptic clustering by dendritic signalling mechanisms. Curr Opin Neurobiol 2008; 18: 321-331.
    • (2008) Curr Opin Neurobiol , vol.18 , pp. 321-331
    • Larkum, M.E.1    Nevian, T.2
  • 12
    • 2542476020 scopus 로고    scopus 로고
    • Computational subunits in thin dendrites of pyramidal cells
    • Polsky A, Mel BW, Schiller J. Computational subunits in thin dendrites of pyramidal cells. Nat Neurosci 2004; 7: 621-627.
    • (2004) Nat Neurosci , vol.7 , pp. 621-627
    • Polsky, A.1    Mel, B.W.2    Schiller, J.3
  • 13
    • 0033607275 scopus 로고    scopus 로고
    • Activity-dependent regulation of synaptic clustering in a hippocampal culture system
    • Kavalali ET, Klingauf J, Tsien RW. Activity-dependent regulation of synaptic clustering in a hippocampal culture system. Proc Natl Acad Sci USA 1999; 96: 12893-12900.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12893-12900
    • Kavalali, E.T.1    Klingauf, J.2    Tsien, R.W.3
  • 14
    • 84155183279 scopus 로고    scopus 로고
    • Activitydependent clustering of functional synaptic inputs on developing hippocampal dendrites
    • Kleindienst T, Winnubst J, Roth-Alpermann C, Bonhoeffer T, Lohmann C. Activitydependent clustering of functional synaptic inputs on developing hippocampal dendrites. Neuron 2011; 72: 1012-1024.
    • (2011) Neuron , vol.72 , pp. 1012-1024
    • Kleindienst, T.1    Winnubst, J.2    Roth-Alpermann, C.3    Bonhoeffer, T.4    Lohmann, C.5
  • 15
    • 54749084700 scopus 로고    scopus 로고
    • LTP promotes a selective long-term stabilization and clustering of dendritic spines
    • De Roo M, Klauser P, Muller D. LTP promotes a selective long-term stabilization and clustering of dendritic spines. PLoS Biol 2008; 6: e219.
    • (2008) PLoS Biol , vol.6 , pp. e219
    • De Roo, M.1    Klauser, P.2    Muller, D.3
  • 16
    • 33751268411 scopus 로고    scopus 로고
    • Pro-survival signalling from the NMDA receptor
    • Hardingham GE. Pro-survival signalling from the NMDA receptor. Biochem Soc Trans 2006; 34: 936-938.
    • (2006) Biochem Soc Trans , vol.34 , pp. 936-938
    • Hardingham, G.E.1
  • 17
    • 77956917231 scopus 로고    scopus 로고
    • Synaptic versus extrasynaptic NMDA receptor signalling: Implications for neurodegenerative disorders
    • Hardingham GE, Bading H. Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat Rev Neurosci 2010; 11: 682-696.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 682-696
    • Hardingham, G.E.1    Bading, H.2
  • 18
    • 0032079863 scopus 로고    scopus 로고
    • Extrasynaptic glutamate diffusion in the hippocampus: Ultrastructural constraints, uptake, and receptor activation
    • Rusakov DA, Kullmann DM. Extrasynaptic glutamate diffusion in the hippocampus: ultrastructural constraints, uptake, and receptor activation. J Neurosci 1998; 18: 3158-3170.
    • (1998) J Neurosci , vol.18 , pp. 3158-3170
    • Rusakov, D.A.1    Kullmann, D.M.2
  • 19
    • 0030782403 scopus 로고    scopus 로고
    • Glutamate transporter protein subtypes are expressed differentially during rat CNS development
    • Furuta A, Rothstein JD, Martin LJ. Glutamate transporter protein subtypes are expressed differentially during rat CNS development. J Neurosci 1997; 17: 8363-8375.
    • (1997) J Neurosci , vol.17 , pp. 8363-8375
    • Furuta, A.1    Rothstein, J.D.2    Martin, L.J.3
  • 20
    • 36348975209 scopus 로고    scopus 로고
    • Glutamate transporters: Confining runaway excitation by shaping synaptic transmission
    • Tzingounis AV, Wadiche JI. Glutamate transporters: confining runaway excitation by shaping synaptic transmission. Nat Rev Neurosci 2007; 8: 935-947.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 935-947
    • Tzingounis, A.V.1    Wadiche, J.I.2
  • 21
    • 78349291932 scopus 로고    scopus 로고
    • Reduction in glutamate uptake is associated with extrasynaptic NMDA and metabotropic glutamate receptor activation at the hippocampal CA1 synapse of aged rats
    • Potier B, Billard JM, Riviere S, Sinet PM, Denis I, Champeil-Potokar G, et al. Reduction in glutamate uptake is associated with extrasynaptic NMDA and metabotropic glutamate receptor activation at the hippocampal CA1 synapse of aged rats. Aging Cell 2010; 9: 722-735.
    • (2010) Aging Cell , vol.9 , pp. 722-735
    • Potier, B.1    Billard, J.M.2    Riviere, S.3    Sinet, P.M.4    Denis, I.5    Champeil-Potokar, G.6
  • 22
    • 84891371475 scopus 로고    scopus 로고
    • Riluzole partially rescues age-associated, but not LPS-induced, loss of glutamate transporters and spatial memory
    • Brothers HM, Bardou I, Hopp SC, Kaercher RM, Corona AW, Fenn AM, et al. Riluzole partially rescues age-associated, but not LPS-induced, loss of glutamate transporters and spatial memory. J Neuroimmune Pharmacol 2013; 8: 1098-1105.
    • (2013) J Neuroimmune Pharmacol , vol.8 , pp. 1098-1105
    • Brothers, H.M.1    Bardou, I.2    Hopp, S.C.3    Kaercher, R.M.4    Corona, A.W.5    Fenn, A.M.6
  • 23
    • 33847725506 scopus 로고    scopus 로고
    • Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease
    • Jacob CP, Koutsilieri E, Bartl J, Neuen-Jacob E, Arzberger T, Zander N, et al. Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease. J Alzheimers Dis 2007; 11: 97-116.
    • (2007) J Alzheimers Dis , vol.11 , pp. 97-116
    • Jacob, C.P.1    Koutsilieri, E.2    Bartl, J.3    Neuen-Jacob, E.4    Arzberger, T.5    Zander, N.6
  • 24
    • 0029811226 scopus 로고    scopus 로고
    • Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease
    • Masliah E, Alford M, DeTeresa R, Mallory M, Hansen L. Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease. Ann Neurol 1996; 40: 759-766.
    • (1996) Ann Neurol , vol.40 , pp. 759-766
    • Masliah, E.1    Alford, M.2    DeTeresa, R.3    Mallory, M.4    Hansen, L.5
  • 25
    • 2942575981 scopus 로고    scopus 로고
    • Glutamate transporters bring competition to the synapse
    • Huang YH, Bergles DE. Glutamate transporters bring competition to the synapse. Curr Opin Neurobiol 2004; 14: 346-352.
    • (2004) Curr Opin Neurobiol , vol.14 , pp. 346-352
    • Huang, Y.H.1    Bergles, D.E.2
  • 26
    • 77951880669 scopus 로고    scopus 로고
    • Glial pathology in an animal model of depression: Reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole
    • Banasr M, Chowdhury GM, Terwilliger R, Newton SS, Duman RS, Behar KL, et al. Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole. Mol Psychiatry 2010; 15: 501-511.
    • (2010) Mol Psychiatry , vol.15 , pp. 501-511
    • Banasr, M.1    Chowdhury, G.M.2    Terwilliger, R.3    Newton, S.S.4    Duman, R.S.5    Behar, K.L.6
  • 27
    • 84943585417 scopus 로고    scopus 로고
    • Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression
    • Hunsberger HC, Weitzner DS, Rudy CC, Hickman JE, Libell EM, Speer RR, et al. Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression. J Neurochem 2015; 135: 381-394.
    • (2015) J Neurochem , vol.135 , pp. 381-394
    • Hunsberger, H.C.1    Weitzner, D.S.2    Rudy, C.C.3    Hickman, J.E.4    Libell, E.M.5    Speer, R.R.6
  • 28
    • 84856677157 scopus 로고    scopus 로고
    • Antidepressant-like properties of oral riluzole and utility of incentive disengagement models of depression in mice
    • Gourley SL, Espitia JW, Sanacora G, Taylor JR. Antidepressant-like properties of oral riluzole and utility of incentive disengagement models of depression in mice. Psychopharmacology 2012; 219: 805-814.
    • (2012) Psychopharmacology , vol.219 , pp. 805-814
    • Gourley, S.L.1    Espitia, J.W.2    Sanacora, G.3    Taylor, J.R.4
  • 30
    • 37349063346 scopus 로고    scopus 로고
    • Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1
    • Fumagalli E, Funicello M, Rauen T, Gobbi M, Mennini T. Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1. Eur J Pharmacol 2008; 578: 171-176.
    • (2008) Eur J Pharmacol , vol.578 , pp. 171-176
    • Fumagalli, E.1    Funicello, M.2    Rauen, T.3    Gobbi, M.4    Mennini, T.5
  • 31
    • 84989225670 scopus 로고    scopus 로고
    • Evaluating whole transcriptome amplification for gene profiling experiments using RNA-Seq
    • Faherty SL, Campbell CR, Larsen PA, Yoder AD. Evaluating whole transcriptome amplification for gene profiling experiments using RNA-Seq. BMC Biotechnol 2015; 15: 65.
    • (2015) BMC Biotechnol , vol.15 , pp. 65
    • Faherty, S.L.1    Campbell, C.R.2    Larsen, P.A.3    Yoder, A.D.4
  • 33
    • 84908555837 scopus 로고    scopus 로고
    • Hippocampal gene expression changes underlying stress sensitization and recovery
    • Gray JD, Rubin TG, Hunter RG, McEwen BS. Hippocampal gene expression changes underlying stress sensitization and recovery. Mol Psychiatry 2014; 19: 1171-1178.
    • (2014) Mol Psychiatry , vol.19 , pp. 1171-1178
    • Gray, J.D.1    Rubin, T.G.2    Hunter, R.G.3    McEwen, B.S.4
  • 34
    • 77955801615 scopus 로고    scopus 로고
    • Galaxy: A comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
    • Goecks J, Nekrutenko A, Taylor J. Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences. Genome Biol 2010; 11: R86.
    • (2010) Genome Biol , vol.11 , pp. R86
    • Goecks, J.1    Nekrutenko, A.2    Taylor, J.3
  • 36
    • 84876996918 scopus 로고    scopus 로고
    • TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
    • Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol 2013; 14: R36.
    • (2013) Genome Biol , vol.14 , pp. R36
    • Kim, D.1    Pertea, G.2    Trapnell, C.3    Pimentel, H.4    Kelley, R.5    Salzberg, S.L.6
  • 37
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 38
    • 84906987763 scopus 로고    scopus 로고
    • Altered expression of diabetes-related genes in Alzheimer's disease brains: The Hisayama study
    • Hokama M, Oka S, Leon J, Ninomiya T, Honda H, Sasaki K, et al. Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study. Cereb Cortex 2014; 24: 2476-2488.
    • (2014) Cereb Cortex , vol.24 , pp. 2476-2488
    • Hokama, M.1    Oka, S.2    Leon, J.3    Ninomiya, T.4    Honda, H.5    Sasaki, K.6
  • 39
    • 34247202571 scopus 로고    scopus 로고
    • Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain
    • Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Walker DG, et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiol Genomics 2007; 28: 311-322.
    • (2007) Physiol Genomics , vol.28 , pp. 311-322
    • Liang, W.S.1    Dunckley, T.2    Beach, T.G.3    Grover, A.4    Mastroeni, D.5    Walker, D.G.6
  • 40
    • 84875262338 scopus 로고    scopus 로고
    • Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease
    • Berchtold NC, Coleman PD, Cribbs DH, Rogers J, Gillen DL, Cotman CW. Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease. Neurobiol Aging 2013; 34: 1653-1661.
    • (2013) Neurobiol Aging , vol.34 , pp. 1653-1661
    • Berchtold, N.C.1    Coleman, P.D.2    Cribbs, D.H.3    Rogers, J.4    Gillen, D.L.5    Cotman, C.W.6
  • 41
    • 84868680722 scopus 로고    scopus 로고
    • Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease
    • Silva AR, Grinberg LT, Farfel JM, Diniz BS, Lima LA, Silva PJ, et al. Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease. PLoS One 2012; 7: e48751.
    • (2012) PLoS One , vol.7 , pp. e48751
    • Silva, A.R.1    Grinberg, L.T.2    Farfel, J.M.3    Diniz, B.S.4    Lima, L.A.5    Silva, P.J.6
  • 42
    • 35448984980 scopus 로고    scopus 로고
    • A SAGE study of apolipoprotein E3/3 E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease
    • Xu PT, Li YJ, Qin XJ, Kroner C, Green-Odlum A, Xu H, et al. A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. Mol Cell Neurosci 2007; 36: 313-331.
    • (2007) Mol Cell Neurosci , vol.36 , pp. 313-331
    • Xu, P.T.1    Li, Y.J.2    Qin, X.J.3    Kroner, C.4    Green-Odlum, A.5    Xu, H.6
  • 44
    • 80052099172 scopus 로고    scopus 로고
    • Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease
    • Blalock EM, Buechel HM, Popovic J, Geddes JW, Landfield PW. Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease. J Chem Neuroanat 2011; 42: 118-126.
    • (2011) J Chem Neuroanat , vol.42 , pp. 118-126
    • Blalock, E.M.1    Buechel, H.M.2    Popovic, J.3    Geddes, J.W.4    Landfield, P.W.5
  • 45
    • 27744576858 scopus 로고    scopus 로고
    • Model-Guided microarray implicates the retromer complex in Alzheimer's disease
    • Small SA, Kent K, Pierce A, Leung C, Kang MS, Okada H, et al. Model-guided microarray implicates the retromer complex in Alzheimer's disease. Ann Neurol 2005; 58: 909-919.
    • (2005) Ann Neurol , vol.58 , pp. 909-919
    • Small, S.A.1    Kent, K.2    Pierce, A.3    Leung, C.4    Kang, M.S.5    Okada, H.6
  • 46
    • 60849111389 scopus 로고    scopus 로고
    • Hippocampal and cognitive aging across the lifespan: A bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment
    • Kadish I, Thibault O, Blalock EM, Chen KC, Gant JC, Porter NM, et al. Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment. J Neurosci 2009; 29: 1805-1816.
    • (2009) J Neurosci , vol.29 , pp. 1805-1816
    • Kadish, I.1    Thibault, O.2    Blalock, E.M.3    Chen, K.C.4    Gant, J.C.5    Porter, N.M.6
  • 47
    • 33947534891 scopus 로고    scopus 로고
    • Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats
    • Rowe WB, Blalock EM, Chen KC, Kadish I, Wang D, Barrett JE, et al. Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats. J Neurosci 2007; 27: 3098-3110.
    • (2007) J Neurosci , vol.27 , pp. 3098-3110
    • Rowe, W.B.1    Blalock, E.M.2    Chen, K.C.3    Kadish, I.4    Wang, D.5    Barrett, J.E.6
  • 48
    • 34047250333 scopus 로고    scopus 로고
    • Maintenance of superior learning and memory function in NR2B transgenic mice during ageing
    • Cao X, Cui Z, Feng R, Tang YP, Qin Z, Mei B, et al. Maintenance of superior learning and memory function in NR2B transgenic mice during ageing. Eur J Neurosci 2007; 25: 1815-1822.
    • (2007) Eur J Neurosci , vol.25 , pp. 1815-1822
    • Cao, X.1    Cui, Z.2    Feng, R.3    Tang, Y.P.4    Qin, Z.5    Mei, B.6
  • 49
    • 36648999558 scopus 로고    scopus 로고
    • Time-dependent molecular memory in single voltage-gated sodium channel
    • Nayak TK, Sikdar SK. Time-dependent molecular memory in single voltage-gated sodium channel. J Membr Biol 2007; 219: 19-36.
    • (2007) J Membr Biol , vol.219 , pp. 19-36
    • Nayak, T.K.1    Sikdar, S.K.2
  • 50
    • 0033860922 scopus 로고    scopus 로고
    • Molecular memory by reversible translocation of calcium/calmodulin-dependent protein kinase II
    • Shen K, Teruel MN, Connor JH, Shenolikar S, Meyer T. Molecular memory by reversible translocation of calcium/calmodulin-dependent protein kinase II. Nat Neurosci 2000; 3: 881-886.
    • (2000) Nat Neurosci , vol.3 , pp. 881-886
    • Shen, K.1    Teruel, M.N.2    Connor, J.H.3    Shenolikar, S.4    Meyer, T.5
  • 51
    • 0033850155 scopus 로고    scopus 로고
    • The role of alpha-CaMKII autophosphorylation in neocortical experience-dependent plasticity
    • Glazewski S, Giese KP, Silva A, Fox K. The role of alpha-CaMKII autophosphorylation in neocortical experience-dependent plasticity. Nat Neurosci 2000; 3: 911-918.
    • (2000) Nat Neurosci , vol.3 , pp. 911-918
    • Glazewski, S.1    Giese, K.P.2    Silva, A.3    Fox, K.4
  • 52
    • 0029875401 scopus 로고    scopus 로고
    • Expression of a phosphorylated isoform of MAP1B is maintained in adult central nervous system areas that retain capacity for structural plasticity
    • Nothias F, Fischer I, Murray M, Mirman S, Vincent JD. Expression of a phosphorylated isoform of MAP1B is maintained in adult central nervous system areas that retain capacity for structural plasticity. J Comp Neurol 1996; 368: 317-334.
    • (1996) J Comp Neurol , vol.368 , pp. 317-334
    • Nothias, F.1    Fischer, I.2    Murray, M.3    Mirman, S.4    Vincent, J.D.5
  • 53
    • 79960111638 scopus 로고    scopus 로고
    • Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3
    • Wang X, McCoy PA, Rodriguiz RM, Pan Y, Je HS, Roberts AC, et al. Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3. Hum Mol Genet 2011; 20: 3093-3108.
    • (2011) Hum Mol Genet , vol.20 , pp. 3093-3108
    • Wang, X.1    McCoy, P.A.2    Rodriguiz, R.M.3    Pan, Y.4    Je, H.S.5    Roberts, A.C.6
  • 55
    • 84856043816 scopus 로고    scopus 로고
    • GABA(A) receptor blockade enhances memory consolidation by increasing hippocampal BDNF levels
    • Kim DH, Kim JM, Park SJ, Cai M, Liu X, Lee S, et al. GABA(A) receptor blockade enhances memory consolidation by increasing hippocampal BDNF levels. Neuropsychopharmacology 2012; 37: 422-433.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 422-433
    • Kim, D.H.1    Kim, J.M.2    Park, S.J.3    Cai, M.4    Liu, X.5    Lee, S.6
  • 56
    • 0025873435 scopus 로고
    • The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3
    • Klein R, Nanduri V, Jing SA, Lamballe F, Tapley P, Bryant S, et al. The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell 1991; 66: 395-403.
    • (1991) Cell , vol.66 , pp. 395-403
    • Klein, R.1    Nanduri, V.2    Jing, S.A.3    Lamballe, F.4    Tapley, P.5    Bryant, S.6
  • 57
    • 84954538622 scopus 로고    scopus 로고
    • Main path and byways: Non-vesicular glutamate release by system x as an important modifier of glutamatergic neurotransmission
    • Massie A, Boillee S, Hewett S, Knackstedt L, Lewerenz J. Main path and byways: non-vesicular glutamate release by system x as an important modifier of glutamatergic neurotransmission. J Neurochem 2015; 135: 1062-1079.
    • (2015) J Neurochem , vol.135 , pp. 1062-1079
    • Massie, A.1    Boillee, S.2    Hewett, S.3    Knackstedt, L.4    Lewerenz, J.5
  • 58
    • 84908223216 scopus 로고    scopus 로고
    • Psychiatric risk factor ANK3/ankyrin-G nanodomains regulate the structure and function of glutamatergic synapses
    • Smith KR, Kopeikina KJ, Fawcett-Patel JM, Leaderbrand K, Gao R, Schurmann B, et al. Psychiatric risk factor ANK3/ankyrin-G nanodomains regulate the structure and function of glutamatergic synapses. Neuron 2014; 84: 399-415.
    • (2014) Neuron , vol.84 , pp. 399-415
    • Smith, K.R.1    Kopeikina, K.J.2    Fawcett-Patel, J.M.3    Leaderbrand, K.4    Gao, R.5    Schurmann, B.6
  • 59
    • 0036513485 scopus 로고    scopus 로고
    • The molecular basis of CaMKII function in synaptic and behavioural memory
    • Lisman J, Schulman H, Cline H. The molecular basis of CaMKII function in synaptic and behavioural memory. Nat Rev Neurosci 2002; 3: 175-190.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 175-190
    • Lisman, J.1    Schulman, H.2    Cline, H.3
  • 60
    • 0035448892 scopus 로고    scopus 로고
    • Rab3A is required for brain-derived neurotrophic factor-induced synaptic plasticity: Transcriptional analysis at the population and single-cell levels
    • Thakker-Varia S, Alder J, Crozier RA, Plummer MR, Black IB. Rab3A is required for brain-derived neurotrophic factor-induced synaptic plasticity: transcriptional analysis at the population and single-cell levels. J Neurosci 2001; 21: 6782-6790.
    • (2001) J Neurosci , vol.21 , pp. 6782-6790
    • Thakker-Varia, S.1    Alder, J.2    Crozier, R.A.3    Plummer, M.R.4    Black, I.B.5
  • 62
    • 0031046153 scopus 로고    scopus 로고
    • Extrasynaptic glutamate spillover in the hippocampus: Dependence on temperature and the role of active glutamate uptake
    • Asztely F, Erdemli G, Kullmann DM. Extrasynaptic glutamate spillover in the hippocampus: dependence on temperature and the role of active glutamate uptake. Neuron 1997; 18: 281-293.
    • (1997) Neuron , vol.18 , pp. 281-293
    • Asztely, F.1    Erdemli, G.2    Kullmann, D.M.3
  • 63
    • 54549086447 scopus 로고    scopus 로고
    • A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: New insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2)
    • Furness DN, Dehnes Y, Akhtar AQ, Rossi DJ, Hamann M, Grutle NJ, et al. A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: new insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2). Neuroscience 2008; 157: 80-94.
    • (2008) Neuroscience , vol.157 , pp. 80-94
    • Furness, D.N.1    Dehnes, Y.2    Akhtar, A.Q.3    Rossi, D.J.4    Hamann, M.5    Grutle, N.J.6
  • 64
    • 84929379714 scopus 로고    scopus 로고
    • Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes
    • Petr GT, Sun Y, Frederick NM, Zhou Y, Dhamne SC, Hameed MQ, et al. Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes. J Neurosci 2015; 35: 5187-5201.
    • (2015) J Neurosci , vol.35 , pp. 5187-5201
    • Petr, G.T.1    Sun, Y.2    Frederick, N.M.3    Zhou, Y.4    Dhamne, S.C.5    Hameed, M.Q.6
  • 65
    • 0842325647 scopus 로고    scopus 로고
    • The glutamate transporter GLT1a is expressed in excitatory axon terminals of mature hippocampal neurons
    • Chen W, Mahadomrongkul V, Berger UV, Bassan M, DeSilva T, Tanaka K, et al. The glutamate transporter GLT1a is expressed in excitatory axon terminals of mature hippocampal neurons. J Neurosci 2004; 24: 1136-1148.
    • (2004) J Neurosci , vol.24 , pp. 1136-1148
    • Chen, W.1    Mahadomrongkul, V.2    Berger, U.V.3    Bassan, M.4    DeSilva, T.5    Tanaka, K.6
  • 66
    • 0026539793 scopus 로고
    • An [Na++K+]coupled L-glutamate transporter purified from rat brain is located in glial cell processes
    • Danbolt NC, Storm-Mathisen J, Kanner BI. An [Na++K+]coupled L-glutamate transporter purified from rat brain is located in glial cell processes. Neuroscience 1992; 51: 295-310.
    • (1992) Neuroscience , vol.51 , pp. 295-310
    • Danbolt, N.C.1    Storm-Mathisen, J.2    Kanner, B.I.3
  • 67
    • 0028958939 scopus 로고
    • Differential expression of two glial glutamate transporters in the rat brain: Quantitative and immunocytochemical observations
    • Lehre KP, Levy LM, Ottersen OP, Storm-Mathisen J, Danbolt NC. Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations. J Neurosci 1995; 15: 1835-1853.
    • (1995) J Neurosci , vol.15 , pp. 1835-1853
    • Lehre, K.P.1    Levy, L.M.2    Ottersen, O.P.3    Storm-Mathisen, J.4    Danbolt, N.C.5
  • 68
  • 69
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe DJ. Alzheimer's disease is a synaptic failure. Science 2002; 298: 789-791.
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 70
    • 0025269152 scopus 로고
    • Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity
    • DeKosky ST, Scheff SW. Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity. Ann Neurol 1990; 27: 457-464.
    • (1990) Ann Neurol , vol.27 , pp. 457-464
    • DeKosky, S.T.1    Scheff, S.W.2
  • 71
    • 67249087641 scopus 로고    scopus 로고
    • Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake
    • Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D. Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron 2009; 62: 788-801.
    • (2009) Neuron , vol.62 , pp. 788-801
    • Li, S.1    Hong, S.2    Shepardson, N.E.3    Walsh, D.M.4    Shankar, G.M.5    Selkoe, D.6
  • 72
    • 79955769953 scopus 로고    scopus 로고
    • Soluble Abeta oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors
    • Li S, Jin M, Koeglsperger T, Shepardson NE, Shankar GM, Selkoe DJ. Soluble Abeta oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors. J Neurosci 2011; 31: 6627-6638.
    • (2011) J Neurosci , vol.31 , pp. 6627-6638
    • Li, S.1    Jin, M.2    Koeglsperger, T.3    Shepardson, N.E.4    Shankar, G.M.5    Selkoe, D.J.6
  • 73
    • 63049085885 scopus 로고    scopus 로고
    • Amyloid beta-protein fragments 25-35 and 31-35 potentiate long-term depression in hippocampal CA1 region of rats in vivo
    • Cheng L, Yin WJ, Zhang JF, Qi JS. Amyloid beta-protein fragments 25-35 and 31-35 potentiate long-term depression in hippocampal CA1 region of rats in vivo. Synapse 2009; 63: 206-214.
    • (2009) Synapse , vol.63 , pp. 206-214
    • Cheng, L.1    Yin, W.J.2    Zhang, J.F.3    Qi, J.S.4
  • 77
    • 84876459364 scopus 로고    scopus 로고
    • Physiological release of endogenous tau is stimulated by neuronal activity
    • Pooler AM, Phillips EC, Lau DH, Noble W, Hanger DP. Physiological release of endogenous tau is stimulated by neuronal activity. EMBO Rep 2013; 14: 389-394.
    • (2013) EMBO Rep , vol.14 , pp. 389-394
    • Pooler, A.M.1    Phillips, E.C.2    Lau, D.H.3    Noble, W.4    Hanger, D.P.5
  • 78
    • 0028173843 scopus 로고
    • Glutamate increases tau phosphorylation in primary neuronal cultures from fetal rat cerebral cortex
    • Sindou P, Lesort M, Couratier P, Yardin C, Esclaire F, Hugon J. Glutamate increases tau phosphorylation in primary neuronal cultures from fetal rat cerebral cortex. Brain Res 1994; 646: 124-128.
    • (1994) Brain Res , vol.646 , pp. 124-128
    • Sindou, P.1    Lesort, M.2    Couratier, P.3    Yardin, C.4    Esclaire, F.5    Hugon, J.6
  • 79
    • 0030769436 scopus 로고    scopus 로고
    • Glutamate toxicity enhances tau gene expression in neuronal cultures
    • Esclaire F, Lesort M, Blanchard C, Hugon J. Glutamate toxicity enhances tau gene expression in neuronal cultures. J Neurosci Res 1997; 49: 309-318.
    • (1997) J Neurosci Res , vol.49 , pp. 309-318
    • Esclaire, F.1    Lesort, M.2    Blanchard, C.3    Hugon, J.4
  • 81
    • 84924709722 scopus 로고    scopus 로고
    • Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease
    • Takahashi K, Kong Q, Lin Y, Stouffer N, Schulte DA, Lai L, et al. Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease. J Exp Med 2015; 212: 319-332.
    • (2015) J Exp Med , vol.212 , pp. 319-332
    • Takahashi, K.1    Kong, Q.2    Lin, Y.3    Stouffer, N.4    Schulte, D.A.5    Lai, L.6
  • 82
    • 0028349645 scopus 로고
    • Glial contributions to excitatory neurotransmission in cultured hippocampal cells
    • Mennerick S, Zorumski CF. Glial contributions to excitatory neurotransmission in cultured hippocampal cells. Nature 1994; 368: 59-62.
    • (1994) Nature , vol.368 , pp. 59-62
    • Mennerick, S.1    Zorumski, C.F.2
  • 83
    • 0028061339 scopus 로고
    • Block of glutamate transporters potentiates postsynaptic excitation
    • Tong G, Jahr CE. Block of glutamate transporters potentiates postsynaptic excitation. Neuron 1994; 13: 1195-1203.
    • (1994) Neuron , vol.13 , pp. 1195-1203
    • Tong, G.1    Jahr, C.E.2
  • 87
    • 85010276111 scopus 로고    scopus 로고
    • Data obtained from the Accelerating Medicines Partnership for Alzheimer's Disease (AMP-AD) Target Discovery Consortium data portal and can be accessed at HYPERLINK. doi:10.7303/syn2580853
    • Data obtained from the Accelerating Medicines Partnership for Alzheimer's Disease (AMP-AD) Target Discovery Consortium data portal and can be accessed at HYPERLINK. http://dx.doi.org/doi:10.7303/syn2580853; doi:10.7303/syn2580853.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.