메뉴 건너뛰기




Volumn 21, Issue 3, 2016, Pages 439-448

Airway epithelial repair in health and disease: Orchestrator or simply a player?

Author keywords

Airway epithelium; Asthma; Cystic fibrosis; Epithelial cell migration; Wound repair

Indexed keywords

ASTHMA; CELL ASSAY; CELL COMMUNICATION; CELL FUNCTION; CELL MIGRATION; CELL REGENERATION; CYSTIC FIBROSIS; DISEASE ACTIVITY; DISEASE ASSOCIATION; EXTRACELLULAR MATRIX; HUMAN; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; REVIEW; SIGNAL TRANSDUCTION; CELLULAR IMMUNITY; CYTOLOGY; EPITHELIUM CELL; IMMUNOLOGY; PATHOLOGY; PHYSIOLOGY; RESPIRATORY MUCOSA; RESPIRATORY TRACT DISEASE;

EID: 84961615511     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/resp.12731     Document Type: Review
Times cited : (24)

References (107)
  • 4
    • 84887007017 scopus 로고    scopus 로고
    • Type 2 innate lymphoid cells constitutively express arginase-I in the naive and inflamed lung
    • Bando JK, Nussbaum JC, Liang HE, Locksley RM,. Type 2 innate lymphoid cells constitutively express arginase-I in the naive and inflamed lung. J. Leukoc. Biol. 2013; 94: 877-884.
    • (2013) J. Leukoc. Biol. , vol.94 , pp. 877-884
    • Bando, J.K.1    Nussbaum, J.C.2    Liang, H.E.3    Locksley, R.M.4
  • 7
    • 84899008777 scopus 로고    scopus 로고
    • Chronic granulomatous disease
    • Leiding J.W. Holland S.M. (eds). University of Washington, Seattle, 1993-2015. [Accessed 29 Jun 2015.] Available from URL
    • Leiding JW, Holland SM,. Chronic granulomatous disease. In:, Leiding JW, Holland SM, (eds) GeneReviews. University of Washington, Seattle, 2012; 1993-2015. [Accessed 29 Jun 2015.] Available from URL: http://www.ncbi.nlm.nih.gov/books/NBK99496
    • (2012) GeneReviews
    • Leiding, J.W.1    Holland, S.M.2
  • 8
    • 84869879700 scopus 로고    scopus 로고
    • Repair of tracheal epithelium by basal cells after chlorine-induced injury
    • Musah S, Chen J, Hoyle GW,. Repair of tracheal epithelium by basal cells after chlorine-induced injury. Respir. Res. 2012; 13: 107.
    • (2012) Respir. Res. , vol.13 , pp. 107
    • Musah, S.1    Chen, J.2    Hoyle, G.W.3
  • 10
    • 0029902823 scopus 로고    scopus 로고
    • Fibronectin and its alpha 5 beta 1-integrin receptor are involved in the wound-repair process of airway epithelium
    • Herard AL, Pierrot D, Hinnrasky J, Kaplan H, Sheppard D, Puchelle E, Zahm JM,. Fibronectin and its alpha 5 beta 1-integrin receptor are involved in the wound-repair process of airway epithelium. Am. J. Physiol. 1996; 271 (5 Pt 1): L726-733.
    • (1996) Am. J. Physiol. , vol.271 , Issue.5 , pp. L726-L733
    • Herard, A.L.1    Pierrot, D.2    Hinnrasky, J.3    Kaplan, H.4    Sheppard, D.5    Puchelle, E.6    Zahm, J.M.7
  • 12
    • 84864741030 scopus 로고    scopus 로고
    • Advances in wound-healing assays for probing collective cell migration
    • Riahi R, Yang Y, Zhang DD, Wong PK,. Advances in wound-healing assays for probing collective cell migration. J. Lab. Autom. 2012; 17: 59-65.
    • (2012) J. Lab. Autom. , vol.17 , pp. 59-65
    • Riahi, R.1    Yang, Y.2    Zhang, D.D.3    Wong, P.K.4
  • 13
    • 84887102273 scopus 로고    scopus 로고
    • Altered microRNA expression profile during epithelial wound repair in bronchial epithelial cells
    • Szczepankiewicz A, Lackie PM, Holloway JW,. Altered microRNA expression profile during epithelial wound repair in bronchial epithelial cells. BMC Pulm. Med. 2013; 13: 63.
    • (2013) BMC Pulm. Med. , vol.13 , pp. 63
    • Szczepankiewicz, A.1    Lackie, P.M.2    Holloway, J.W.3
  • 14
    • 42049084004 scopus 로고    scopus 로고
    • Maintenance and repair of the bronchiolar epithelium
    • Stripp BR, Reynolds SD,. Maintenance and repair of the bronchiolar epithelium. Proc. Am. Thorac. Soc. 2008; 5: 328-333.
    • (2008) Proc. Am. Thorac. Soc. , vol.5 , pp. 328-333
    • Stripp, B.R.1    Reynolds, S.D.2
  • 17
    • 0038676822 scopus 로고    scopus 로고
    • Fibronectin matrix polymerization regulates small airway epithelial cell migration
    • Hocking DC, Chang CH,. Fibronectin matrix polymerization regulates small airway epithelial cell migration. Am. J. Physiol. Lung Cell. Mol. Physiol. 2003; 285: L169-179.
    • (2003) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.285 , pp. L169-L179
    • Hocking, D.C.1    Chang, C.H.2
  • 19
    • 84908350153 scopus 로고    scopus 로고
    • Revisiting the matricellular concept
    • Murphy-Ullrich JE, Sage EH,. Revisiting the matricellular concept. Matrix Biol. 2014; 37: 1-14.
    • (2014) Matrix Biol. , vol.37 , pp. 1-14
    • Murphy-Ullrich, J.E.1    Sage, E.H.2
  • 21
    • 77049098424 scopus 로고    scopus 로고
    • Differential regulation of galectin expression/reactivity during wound healing in porcine skin and in cultures of epidermal cells with functional impact on migration
    • Klima J, Lacina L, Dvorankova B, Herrmann D, Carnwath JW, Niemann H, Kaltner H, Andre S, Motlik J, Gabius HJ, et al. Differential regulation of galectin expression/reactivity during wound healing in porcine skin and in cultures of epidermal cells with functional impact on migration. Physiol. Res. 2009; 58: 873-884.
    • (2009) Physiol. Res. , vol.58 , pp. 873-884
    • Klima, J.1    Lacina, L.2    Dvorankova, B.3    Herrmann, D.4    Carnwath, J.W.5    Niemann, H.6    Kaltner, H.7    Andre, S.8    Motlik, J.9    Gabius, H.J.10
  • 22
    • 36849067117 scopus 로고    scopus 로고
    • The role of galectin-3 in promotion of the inflammatory response
    • Liu FT, Hsu DK,. The role of galectin-3 in promotion of the inflammatory response. Drug News Perspect. 2007; 20: 455-460.
    • (2007) Drug News Perspect. , vol.20 , pp. 455-460
    • Liu, F.T.1    Hsu, D.K.2
  • 23
    • 84908278609 scopus 로고    scopus 로고
    • Proteomics of bronchial biopsies: Galectin-3 as a predictive biomarker of airway remodelling modulation in omalizumab-treated severe asthma patients
    • Mauri P, Riccio AM, Rossi R, Di Silvestre D, Benazzi L, De Ferrari L, Dal Negro RW, Holgate ST, Canonica GW,. Proteomics of bronchial biopsies: galectin-3 as a predictive biomarker of airway remodelling modulation in omalizumab-treated severe asthma patients. Immunol. Lett. 2014; 162 (1 Pt A): 2-10.
    • (2014) Immunol. Lett. , vol.162 , Issue.1 , pp. 2-10
    • Mauri, P.1    Riccio, A.M.2    Rossi, R.3    Di Silvestre, D.4    Benazzi, L.5    De Ferrari, L.6    Dal Negro, R.W.7    Holgate, S.T.8    Canonica, G.W.9
  • 24
    • 0022448122 scopus 로고
    • Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin
    • Tamkun JW, DeSimone DW, Fonda D, Patel RS, Buck C, Horwitz AF, Hynes RO,. Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin. Cell 1986; 46: 271-282.
    • (1986) Cell , vol.46 , pp. 271-282
    • Tamkun, J.W.1    DeSimone, D.W.2    Fonda, D.3    Patel, R.S.4    Buck, C.5    Horwitz, A.F.6    Hynes, R.O.7
  • 27
    • 0037662109 scopus 로고    scopus 로고
    • Functions of pulmonary epithelial integrins: From development to disease
    • Sheppard D,. Functions of pulmonary epithelial integrins: from development to disease. Physiol. Rev. 2003; 83: 673-686.
    • (2003) Physiol. Rev. , vol.83 , pp. 673-686
    • Sheppard, D.1
  • 28
    • 0033109382 scopus 로고    scopus 로고
    • Role of very late adhesion integrins in mediating repair of human airway epithelial cell monolayers after mechanical injury
    • White SR, Dorscheid DR, Rabe KF, Wojcik KR, Hamann KJ,. Role of very late adhesion integrins in mediating repair of human airway epithelial cell monolayers after mechanical injury. Am. J. Respir. Cell Mol. Biol. 1999; 20: 787-796.
    • (1999) Am. J. Respir. Cell Mol. Biol. , vol.20 , pp. 787-796
    • White, S.R.1    Dorscheid, D.R.2    Rabe, K.F.3    Wojcik, K.R.4    Hamann, K.J.5
  • 30
    • 0037568364 scopus 로고    scopus 로고
    • Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium
    • McGuire JK, Li Q, Parks WC,. Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium. Am. J. Pathol. 2003; 162: 1831-1843.
    • (2003) Am. J. Pathol. , vol.162 , pp. 1831-1843
    • McGuire, J.K.1    Li, Q.2    Parks, W.C.3
  • 31
    • 68749110934 scopus 로고    scopus 로고
    • MMP7 shedding of syndecan-1 facilitates re-epithelialization by affecting alpha(2)beta(1) integrin activation
    • Chen P, Abacherli LE, Nadler ST, Wang Y, Li Q, Parks WC,. MMP7 shedding of syndecan-1 facilitates re-epithelialization by affecting alpha(2)beta(1) integrin activation. PLoS ONE 2009; 4: e6565.
    • (2009) PLoS ONE , vol.4 , pp. e6565
    • Chen, P.1    Abacherli, L.E.2    Nadler, S.T.3    Wang, Y.4    Li, Q.5    Parks, W.C.6
  • 33
    • 0029965504 scopus 로고    scopus 로고
    • Wound repair-induced expression of a stromelysins is associated with the acquisition of a mesenchymal phenotype in human respiratory epithelial cells
    • Buisson AC, Gilles C, Polette M, Zahm JM, Birembaut P, Tournier JM,. Wound repair-induced expression of a stromelysins is associated with the acquisition of a mesenchymal phenotype in human respiratory epithelial cells. Lab. Invest. 1996; 74: 658-669.
    • (1996) Lab. Invest. , vol.74 , pp. 658-669
    • Buisson, A.C.1    Gilles, C.2    Polette, M.3    Zahm, J.M.4    Birembaut, P.5    Tournier, J.M.6
  • 34
    • 34548383843 scopus 로고    scopus 로고
    • Membrane type 1 matrix metalloproteinase is necessary for distal airway epithelial repair and keratinocyte growth factor receptor expression after acute injury
    • Atkinson JJ, Toennies HM, Holmbeck K, Senior RM,. Membrane type 1 matrix metalloproteinase is necessary for distal airway epithelial repair and keratinocyte growth factor receptor expression after acute injury. Am. J. Physiol. Lung Cell. Mol. Physiol. 2007; 293: L600-610.
    • (2007) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.293 , pp. L600-L610
    • Atkinson, J.J.1    Toennies, H.M.2    Holmbeck, K.3    Senior, R.M.4
  • 36
    • 84863878959 scopus 로고    scopus 로고
    • Cross talk among TGF-beta signaling pathways, integrins, and the extracellular matrix
    • Munger JS, Sheppard D,. Cross talk among TGF-beta signaling pathways, integrins, and the extracellular matrix. Cold Spring Harb. Perspect. Biol. 2011; 3: A005017.
    • (2011) Cold Spring Harb. Perspect. Biol. , vol.3 , pp. A005017
    • Munger, J.S.1    Sheppard, D.2
  • 37
    • 33847619244 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activator
    • Crippa MP,. Urokinase-type plasminogen activator. Int. J. Biochem. Cell Biol. 2007; 39: 690-694.
    • (2007) Int. J. Biochem. Cell Biol. , vol.39 , pp. 690-694
    • Crippa, M.P.1
  • 39
    • 56549126795 scopus 로고    scopus 로고
    • Dysregulated repair in asthmatic paediatric airway epithelial cells: The role of plasminogen activator inhibitor-1
    • Stevens PT, Kicic A, Sutanto EN, Knight DA, Stick SM,. Dysregulated repair in asthmatic paediatric airway epithelial cells: the role of plasminogen activator inhibitor-1. Clin. Exp. Allergy 2008; 38: 1901-1910.
    • (2008) Clin. Exp. Allergy , vol.38 , pp. 1901-1910
    • Stevens, P.T.1    Kicic, A.2    Sutanto, E.N.3    Knight, D.A.4    Stick, S.M.5
  • 40
    • 79957922264 scopus 로고    scopus 로고
    • The three R's of lung health and disease: Repair, remodeling, and regeneration
    • Beers MF, Morrisey EE,. The three R's of lung health and disease: repair, remodeling, and regeneration. J. Clin. Invest. 2011; 121: 2065-2073.
    • (2011) J. Clin. Invest. , vol.121 , pp. 2065-2073
    • Beers, M.F.1    Morrisey, E.E.2
  • 44
    • 83655190177 scopus 로고    scopus 로고
    • Cigarette smoke impairs airway epithelial barrier function and cell-cell contact recovery
    • Heijink IH, Brandenburg SM, Postma DS, van Oosterhout AJ,. Cigarette smoke impairs airway epithelial barrier function and cell-cell contact recovery. Eur. Respir. J. 2012; 39: 419-428.
    • (2012) Eur. Respir. J. , vol.39 , pp. 419-428
    • Heijink, I.H.1    Brandenburg, S.M.2    Postma, D.S.3    Van Oosterhout, A.J.4
  • 45
    • 79958120387 scopus 로고    scopus 로고
    • Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury
    • Zhou F, Onizawa S, Nagai A, Aoshiba K,. Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury. Respir. Res. 2011; 12: 78.
    • (2011) Respir. Res. , vol.12 , pp. 78
    • Zhou, F.1    Onizawa, S.2    Nagai, A.3    Aoshiba, K.4
  • 48
    • 85031965880 scopus 로고    scopus 로고
    • Asthmatic airway epithelial cells exhibit delayed wound closure and cell proliferation, effects enhanced by IL-13
    • Hideki I, Takeshi H, Xiuxia Z, Haizhen H, John BT, Sally EW,. Asthmatic airway epithelial cells exhibit delayed wound closure and cell proliferation, effects enhanced by IL-13. Am. J. Resp. Crit. Care Med. 2015; 257: A5976.
    • (2015) Am. J. Resp. Crit. Care Med. , vol.257 , pp. A5976
    • Hideki, I.1    Takeshi, H.2    Xiuxia, Z.3    Haizhen, H.4    John, B.T.5    Sally, E.W.6
  • 49
    • 84861870816 scopus 로고    scopus 로고
    • UPAR regulates bronchial epithelial repair in vitro and is elevated in asthmatic epithelium
    • Stewart CE, Nijmeh HS, Brightling CE, Sayers I,. uPAR regulates bronchial epithelial repair in vitro and is elevated in asthmatic epithelium. Thorax 2012; 67: 477-487.
    • (2012) Thorax , vol.67 , pp. 477-487
    • Stewart, C.E.1    Nijmeh, H.S.2    Brightling, C.E.3    Sayers, I.4
  • 53
    • 78349273579 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane conductance regulator is involved in airway epithelial wound repair
    • Schiller KR, Maniak PJ, O'Grady SM,. Cystic fibrosis transmembrane conductance regulator is involved in airway epithelial wound repair. Am. J. Physiol. Lung Cell. Mol. Physiol. 2010; 299: C912-921.
    • (2010) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.299 , pp. C912-C921
    • Schiller, K.R.1    Maniak, P.J.2    O'Grady, S.M.3
  • 58
    • 84894034462 scopus 로고    scopus 로고
    • Alveolar epithelial cells in idiopathic pulmonary fibrosis display upregulation of TRAIL, DR4 and DR5 expression with simultaneous preferential over-expression of pro-apoptotic marker p53
    • Akram KM, Lomas NJ, Forsyth NR, Spiteri MA,. Alveolar epithelial cells in idiopathic pulmonary fibrosis display upregulation of TRAIL, DR4 and DR5 expression with simultaneous preferential over-expression of pro-apoptotic marker p53. Int. J. Clin. Exp. Pathol. 2014; 7: 552-564.
    • (2014) Int. J. Clin. Exp. Pathol. , vol.7 , pp. 552-564
    • Akram, K.M.1    Lomas, N.J.2    Forsyth, N.R.3    Spiteri, M.A.4
  • 59
    • 80155134142 scopus 로고    scopus 로고
    • Extracellular matrix powder protects against bleomycin-induced pulmonary fibrosis
    • Manni ML, Czajka CA, Oury TD, Gilbert TW,. Extracellular matrix powder protects against bleomycin-induced pulmonary fibrosis. Tissue Eng Part A 2011; 17: 2795-2804.
    • (2011) Tissue Eng Part A , vol.17 , pp. 2795-2804
    • Manni, M.L.1    Czajka, C.A.2    Oury, T.D.3    Gilbert, T.W.4
  • 60
    • 0026769303 scopus 로고
    • The site of disruption of the bronchial epithelium in asthmatic and non-asthmatic subjects
    • Montefort S, Roberts JA, Beasley R, Holgate ST, Roche WR,. The site of disruption of the bronchial epithelium in asthmatic and non-asthmatic subjects. Thorax 1992; 47: 499-503.
    • (1992) Thorax , vol.47 , pp. 499-503
    • Montefort, S.1    Roberts, J.A.2    Beasley, R.3    Holgate, S.T.4    Roche, W.R.5
  • 61
    • 77956623567 scopus 로고    scopus 로고
    • A look at the pathogenesis of asthma: The need for a change in direction
    • Holgate ST,. A look at the pathogenesis of asthma: the need for a change in direction. Discov. Med. 2010; 9: 439-447.
    • (2010) Discov. Med. , vol.9 , pp. 439-447
    • Holgate, S.T.1
  • 62
    • 84865145614 scopus 로고    scopus 로고
    • Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
    • Pavord ID, Korn S, Howarth P, Bleecker ER, Buhl R, Keene ON, Ortega H, Chanez P,. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet 2012; 380: 651-659.
    • (2012) Lancet , vol.380 , pp. 651-659
    • Pavord, I.D.1    Korn, S.2    Howarth, P.3    Bleecker, E.R.4    Buhl, R.5    Keene, O.N.6    Ortega, H.7    Chanez, P.8
  • 64
    • 33751082383 scopus 로고    scopus 로고
    • Intrinsic biochemical and functional differences in bronchial epithelial cells of children with asthma
    • Kicic A, Sutanto EN, Stevens PT, Knight DA, Stick SM,. Intrinsic biochemical and functional differences in bronchial epithelial cells of children with asthma. Am. J. Respir. Crit. Care Med. 2006; 174: 1110-1118.
    • (2006) Am. J. Respir. Crit. Care Med. , vol.174 , pp. 1110-1118
    • Kicic, A.1    Sutanto, E.N.2    Stevens, P.T.3    Knight, D.A.4    Stick, S.M.5
  • 68
    • 84887129738 scopus 로고    scopus 로고
    • Responses of airway epithelium to environmental injury: Role in the induction phase of childhood asthma
    • Kumar RK, Siegle JS, Kaiko GE, Herbert C, Mattes JE, Foster PS,. Responses of airway epithelium to environmental injury: role in the induction phase of childhood asthma. J. Allergy (Cairo) 2011; 2011: 257017.
    • (2011) J. Allergy (Cairo) , vol.2011 , pp. 257017
    • Kumar, R.K.1    Siegle, J.S.2    Kaiko, G.E.3    Herbert, C.4    Mattes, J.E.5    Foster, P.S.6
  • 69
    • 84860691114 scopus 로고    scopus 로고
    • The airway epithelium in asthma
    • Lambrecht BN, Hammad H,. The airway epithelium in asthma. Nat. Med. 2012; 18: 684-692.
    • (2012) Nat. Med. , vol.18 , pp. 684-692
    • Lambrecht, B.N.1    Hammad, H.2
  • 70
    • 40949121542 scopus 로고    scopus 로고
    • The airway epithelium is central to the pathogenesis of asthma
    • Holgate ST,. The airway epithelium is central to the pathogenesis of asthma. Allergol. Int. 2008; 57: 1-10.
    • (2008) Allergol. Int. , vol.57 , pp. 1-10
    • Holgate, S.T.1
  • 72
    • 14644412828 scopus 로고    scopus 로고
    • Markers of eosinophilic inflammation and tissue re-modelling in children before clinically diagnosed bronchial asthma
    • Pohunek P, Warner JO, Turzikova J, Kudrmann J, Roche WR,. Markers of eosinophilic inflammation and tissue re-modelling in children before clinically diagnosed bronchial asthma. Pediatr. Allergy Immunol. 2005; 16: 43-51.
    • (2005) Pediatr. Allergy Immunol. , vol.16 , pp. 43-51
    • Pohunek, P.1    Warner, J.O.2    Turzikova, J.3    Kudrmann, J.4    Roche, W.R.5
  • 79
    • 74049121313 scopus 로고    scopus 로고
    • IL-33: A tissue derived cytokine pathway involved in allergic inflammation and asthma
    • Smith DE,. IL-33: a tissue derived cytokine pathway involved in allergic inflammation and asthma. Clin. Exp. Allergy 2010; 40: 200-208.
    • (2010) Clin. Exp. Allergy , vol.40 , pp. 200-208
    • Smith, D.E.1
  • 84
    • 0032433707 scopus 로고    scopus 로고
    • Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
    • Matsui H, Grubb BR, Tarran R, Randell SH, Gatzy JT, Davis CW, Boucher RC,. Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease. Cell 1998; 95: 1005-1015.
    • (1998) Cell , vol.95 , pp. 1005-1015
    • Matsui, H.1    Grubb, B.R.2    Tarran, R.3    Randell, S.H.4    Gatzy, J.T.5    Davis, C.W.6    Boucher, R.C.7
  • 86
    • 84876531002 scopus 로고    scopus 로고
    • The level of p38α mitogen-activated protein kinase activation in airway epithelial cells determines the onset of innate immune responses to planktonic and biofilm Pseudomonas aeruginosa
    • Beaudoin T, LaFayette S, Roussel L, Bérubé J, Desrosiers M, Nguyen D, Rousseau S,. The level of p38α mitogen-activated protein kinase activation in airway epithelial cells determines the onset of innate immune responses to planktonic and biofilm Pseudomonas aeruginosa. J. Infect. Dis. 2013; 207: 1544-1555.
    • (2013) J. Infect. Dis. , vol.207 , pp. 1544-1555
    • Beaudoin, T.1    LaFayette, S.2    Roussel, L.3    Bérubé, J.4    Desrosiers, M.5    Nguyen, D.6    Rousseau, S.7
  • 87
    • 84961652030 scopus 로고    scopus 로고
    • Exaggerated innate immune responses to rhinovirus infection in airway epithelial cells (AEC) from children with cystic fibrosis
    • CF A, AREST CF.
    • Saferali A, Gill E, Sandford AJ, Hancock REW, Kicic A, Stick SM, Turvey SE, CF A, AREST CF. Exaggerated innate immune responses to rhinovirus infection in airway epithelial cells (AEC) from children with cystic fibrosis. Pediatr. Pulmonol. 2015; 50 (S41): 242.
    • (2015) Pediatr. Pulmonol. , vol.50 , Issue.S41 , pp. 242
    • Saferali, A.1    Gill, E.2    Sandford, A.J.3    Hancock, R.E.W.4    Kicic, A.5    Stick, S.M.6    Turvey, S.E.7
  • 90
    • 75849161721 scopus 로고    scopus 로고
    • Cystic fibrosis lung disease starts in the small airways: Can we treat it more effectively?
    • Tiddens HAWM, Donaldson SH, Rosenfeld M, Paré PD,. Cystic fibrosis lung disease starts in the small airways: can we treat it more effectively? Pediatr. Pulmonol. 2010; 45: 107-117.
    • (2010) Pediatr. Pulmonol. , vol.45 , pp. 107-117
    • Tiddens, H.A.W.M.1    Donaldson, S.H.2    Rosenfeld, M.3    Paré, P.D.4
  • 91
    • 0030053047 scopus 로고    scopus 로고
    • Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention
    • Pahl HL, Sester M, Burgert HG, Baeuerle PA,. Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention. J. Cell Biol. 1996; 132: 511-522.
    • (1996) J. Cell Biol. , vol.132 , pp. 511-522
    • Pahl, H.L.1    Sester, M.2    Burgert, H.G.3    Baeuerle, P.A.4
  • 92
    • 33846570486 scopus 로고    scopus 로고
    • Human airway surface epithelial regeneration is delayed and abnormal in cystic fibrosis
    • Hajj R, Lesimple P, Nawrocki-Raby B, Birembaut P, Puchelle E, Coraux C,. Human airway surface epithelial regeneration is delayed and abnormal in cystic fibrosis. J. Pathol. 2007; 211: 340-350.
    • (2007) J. Pathol. , vol.211 , pp. 340-350
    • Hajj, R.1    Lesimple, P.2    Nawrocki-Raby, B.3    Birembaut, P.4    Puchelle, E.5    Coraux, C.6
  • 93
    • 0030836678 scopus 로고    scopus 로고
    • Expression of integrin cell adhesion receptors during human airway epithelial repair in vivo
    • Pilewski JM, Latoche JD, Arcasoy SM, Albelda SM,. Expression of integrin cell adhesion receptors during human airway epithelial repair in vivo. Am. J. Physiol. 1997; 273 (1 Pt 1): L256-263.
    • (1997) Am. J. Physiol. , vol.273 , Issue.1 , pp. L256-L263
    • Pilewski, J.M.1    Latoche, J.D.2    Arcasoy, S.M.3    Albelda, S.M.4
  • 96
    • 84900563188 scopus 로고    scopus 로고
    • Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair
    • Itokazu Y, Pagano RE, Schroeder AS, O'Grady SM, Limper AH, Marks DL,. Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair. Am. J. Physiol. Cell Physiol. 2014; 306: C819-830.
    • (2014) Am. J. Physiol. Cell Physiol. , vol.306 , pp. C819-C830
    • Itokazu, Y.1    Pagano, R.E.2    Schroeder, A.S.3    O'Grady, S.M.4    Limper, A.H.5    Marks, D.L.6
  • 97
    • 0035888715 scopus 로고    scopus 로고
    • Airway inflammation in children with cystic fibrosis and healthy children assessed by sputum induction
    • Sagel SD, Kapsner R, Osberg I, Sontag MK, Accurso FJ,. Airway inflammation in children with cystic fibrosis and healthy children assessed by sputum induction. Am. J. Respir. Crit. Care Med. 2001; 164: 1425-1431.
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , pp. 1425-1431
    • Sagel, S.D.1    Kapsner, R.2    Osberg, I.3    Sontag, M.K.4    Accurso, F.J.5
  • 104
    • 16244368754 scopus 로고    scopus 로고
    • Induced sputum matrix metalloproteinase-9 correlates with lung function and airway inflammation in children with cystic fibrosis
    • Sagel SD, Kapsner RK, Osberg I,. Induced sputum matrix metalloproteinase-9 correlates with lung function and airway inflammation in children with cystic fibrosis. Pediatr. Pulmonol. 2005; 39: 224-232.
    • (2005) Pediatr. Pulmonol. , vol.39 , pp. 224-232
    • Sagel, S.D.1    Kapsner, R.K.2    Osberg, I.3
  • 106
    • 0028104433 scopus 로고
    • Matrilysin is much more efficient than other matrix metalloproteinases in the proteolytic inactivation of alpha 1-antitrypsin
    • Sires UI, Murphy G, Baragi VM, Fliszar CJ, Welgus HG, Senior RM,. Matrilysin is much more efficient than other matrix metalloproteinases in the proteolytic inactivation of alpha 1-antitrypsin. Biochem. Biophys. Res. Commun. 1994; 204: 613-620.
    • (1994) Biochem. Biophys. Res. Commun. , vol.204 , pp. 613-620
    • Sires, U.I.1    Murphy, G.2    Baragi, V.M.3    Fliszar, C.J.4    Welgus, H.G.5    Senior, R.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.